高综合性能低碱微膨胀中热硅酸盐水泥的设计与生产制备

针对低碱微胀中热硅酸盐熟料及水泥生产制备长期存在各项主要技术指标顾此失彼的问题,通过实际生产产品技术数据的总结分析,查找不足,梳理技术原理及应用,按照平衡性原则设计低碱微膨胀中热硅酸盐熟料及水泥主要技术指标,经过工业生产制备的实施,全面大幅度地提升低碱微膨胀中热水泥的综合性能,收到显著的效果。

高综合性能无色透明聚酰亚胺薄膜的制备

以2,2’-双(三氟甲氧基)联苯-4,4’-二胺(TFMOB)/2,2’-双(三氟甲基)联苯-4,4’-二胺(TFMB)为二胺单体,分别与六氟异丙基邻苯二甲酸酐(6FDA)和4,4’-(4,4’-异丙基二苯氧基)双(邻苯二甲酸酐)(BPADA)2种二酐单体聚合,制备了含三氟甲氧基(―OCF_(3))的新型无色透明聚酰亚胺(CPI)薄膜.实验结果表明:―OCF_(3)的引入明显提高了CPI薄膜的综合性能,TFMOB与TFMB的摩尔比为3:7时,在400~760 nm可见光波长范围内,透光率大于85%;5%质量损失对应的热分解温度(N2氛围)在530℃以上;10 GHz频率下的介电常数为2.647,介电损耗为0.00525;拉伸强度达(111.2±1.1)MPa,断裂伸长率为(67.0±5.0)%,吸湿率最低可达0.29%.证明含―OCF_(3)基团的TFMOB单体为高综合性能CPI薄膜的制备提供了可能,在柔性光学材料方面具有良好的应用前景.

一种超低表面张力高性能起泡剂的制备方法与性能测试

此高性能起泡剂适用于油气田开发领域,其起泡量高、泡沫稳定性好、高温条件下也能达到理想效果,可以很好地应运用于油气田钻井、洗井、压裂、排水采气等多个环节,包括如下重量百分比的组分,烷基糖苷20%~30%,椰子油脂肪酸丙氨酸钠3%~10%,月桂酰胺丙基氧化胺5%~10%,椰油酰胺丙基氧化胺1.0%~1.5%,十二烷基二甲基氧化胺5%~15%,硅树脂聚醚乳液0.5%~2%和去离子水35%~60%,其中综合最优配方为烷基糖苷25%,椰子油脂肪酸丙氨酸钠10%,月桂酰胺丙基氧化胺10%,椰油酰胺丙基氧化胺1%,十二烷基二甲基氧化胺10%,硅树脂聚醚乳液1%和去离子水43%。

新型高性能钛合金研究与应用

随着钛合金在我国航空、航天、兵器、海洋和化工等领域用量和应用范围的不断扩大,对钛合金高综合力学性能、低成本和加工工艺性能提出了更加苛刻的要求。通过基于组织参数设计的合金化、细晶强化、相变强化和强韧化工艺控制等综合强韧化技术,研制出具有高强韧、抗疲劳、耐损伤、抗冲击等综合性能良好匹配的新型高性能钛合金,是扩大钛合金在高端领域的用量与应用水平,实现产业升级转型,满足下一代应用需求的重要保障。

磁悬浮高速铁路球墨铸铁连接件的研制和生产

详细介绍了有特殊力学性能要求的磁悬浮高速铁路复合梁球墨铸铁连接件的研制和生产过程。为了达到高强度、高塑性、并符合低温冲击韧性要求的综合力学性能,进行大量试验比较了各种合金化方案,根据大量实验和研究数据分据,查明了大量生产条件下,该合金球墨铸铁件可能达到的抗拉强度、伸长率和低温冲击值范围,为最终确定该铸件力学性能要求提供了科学依据;进而确定化学成分和铸造工艺,成功试制并大量生产出该铸件。

我国航空用钛合金技术研究现状及发展

我国海绵钛和钛加工材的产能已经跃居世界第一位,但与发达国家相比,在技术水平和高端应用上仍存在较大差距。综述我国航空用钛合金的技术研究现状,提出未来钛合金发展应从综合性能优化、规格品种齐全、应用规模扩大、规范标准完善、考核验证数据充分等方面提高主干钛合金技术成熟度,按体系发展原则,建立航空用钛合金材料系列,实现产业结构升级、技术成熟度提升、减能增效、低成本制造及扩大用量等产业化应用目标。

浅谈医院的建筑设计

本文介绍了设计现代化医院所应注意的问题，提出对我国现代化医院的建筑设计的构想。

Investigation on Risk Factors of Cerebrocardiac Vascular Thrombotic Diseases in Patients with Obstructive Sleep Apnea Hypopnea Syndrome

Objective: To observe the risk factors of thrombosis in patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods: From February 2001 to April 2003, 24 patients with moderate and severe OSAHS (OSAHS group) and 19 healthy adults (control group) were recruited. Their blood samples were drawn at 6∶00 and 16∶00 respectively for testing hemocrit, platelet aggregation (PAG), whole blood viscosity (WBV), prothrombin time (PT), activated partial thromboplastin time (APTT), plasma fibrinogen (Fng) and endothelin (ET).Results: There was a significantly higher hemocrit, WBV, Fng and ET as well as a significant shortening of PT and APTT at 6∶00 than that at 16∶00 in OSAHS group. However, there was no significant difference in all testing items between 6∶00 and 16∶00 in control group. The hemocrit, WBV, PAG, plasma Fng and ET were significantly higher, and PT and APTT were obviously shorter at 6∶00 in OSAHS group than those at 6∶00 in control group. A higher hemocrit, PAG, plasma Fng and ET, a longer PT and APTT were observed at 16∶00 in OSAHS group, compared with those at 16∶00 in control group.Conclusion: In OSAHS patients there were striking risk factors of thrombosis, which is more remarkable in the early morning than in the afternoon.

Pathological and High Resolution CT Findings in Churg-Strauss Syndrome

Objective To investigate the Churg-Strauss syndrome （CSS） associated lung involvement, concentrating on clinical characteristics, pathological findings of tung involvements, response to treatment, and prognosis. Methods We retrospectively analyzed the characters of the clinical manifestations, thin-section CT and pathological findings of CSS. The study involved 16 patients. Clinical data were obtained by chart review All patients underwent transbronchial lung biopsy （TBLB）. Six of them underwent surgical lung biopsy as well. Results The patients included 7 men and 9 women, aged from 14 to 61 years （median, 47.5 years）. Extrathoracic organs involved included nervous system （7/16） and skin （5/16）. Respiratory symptoms included cough （12/16）, exertional dyspnea （11/16）, hemoptysis （4/16）, and chest pain （3/16）. CT findings included bilateral ground-glass opacities （12 / 16）, bilateral patchy opacities （12 / 16）, and centrilobular nodules （6/16）. The pathological findings of TBLB demonstrated increased eosinophils （3/16）, vasculitis （3/16）, and interstitial pneumonia （16/16）. The pathological fmdings of surgical lung biopsy of 6 cases showed necrotizing vasculitis in 4 cases, capillaries in 5, eosinophilic pneumonia in 3, granulomas in 2, and airway abnormalities in 3. All patients improved in symptoms after therapy during the study period （range, 3 to 51 months; median, 15 months）. Conclusions Asthma may be present in CSS patient when there is bronchial involvement. Grotmd-glass opacities and consolidation seen on high-resolution CT reflect the presence of eosinophilic pneumonia, vasculitis, and pulmonary alveolar hemorrhage. TBLB has significant limitations for the diagnosis of CSS. Early diagnosis and therapy can result in satisfactory prognosis.

Relationship of serum vitamin D level on geriatric syndromes and physical performance impairment in elderly hypertensive patients

Objective To investigate the relationship among serum vitamin D levels, physical performance impairment, and geriatric syndromes in elders with hypertension. Methods According to the concentration of vitamin D levels, a total of 143 elderly patients with hypertension were classified into vitamin D deficient group （vitamin D 〈 20 ng/mL, n = 94） and vitamin D appropriate group （vitamin D 〉 20 ng/rnL, n = 49）. Geriatric syndromes and physical performance were assessed by using comprehensive geriatric assessment （CGA）. Correlation among vitamin D levels, geriatric syndromes and physical performance was analyzed. Results No statistical differences were found in various aspects of geriatric syndromes between the two groups （P 〉 0.05）. While correlation analysis indicated that vitamin D levels had a positive association with ADL score （r = 0.235, P 〈 0.01） and a negative association with Morse fall scale score （r = 0.238, P 〈 0.01）. Patients with deficient vitamin D level had longer time both in the Five Time Sit to Stand Test （5tSTS）, （15.765 ± 5.593） and the four-meter walk test [7.440 （5.620, 9.200）], a weaker hand-grip in the grip strength test （28.049 ± 9.522）, and a lower Tinetti performance-oriented mobility assessment （Tinetti POMA） [26 （22, 27）] and Balance subscale of the Tinetti performance-oriented mobility assessment （B-POMA） score [ 14 （12, 16）], compared with appropriate vitamin D level [（13.275 ± 3.692）; 5.810 （4.728, 7.325）]; （31.989 ± 10.217）; [26.5 （25, 28）]; [15 （14, 16）, respectively, all P 〈 0.05]. Furthermore, results of logistic regression indicated that vitamin D was significantly associated with 5tSTS （OR = 1.2, 95% CI = 1.050-1.331, P 〈 0.01）, Tinetti POMA （OR = 3.7, 95% CI：1.284-10.830, P 〈 0.05） and B-POMA （OR = 0.8, 95% CI：0.643-0.973, P 〈 0.05）. Conclusions In elderly hypertensive patients, serum vitamin D deficient level is associated with physical performance impairment. However, no statistical significance was found between vitamin D and geriatric syndromes. Further study is required to investigate possible mechanisms for the association between vitamin D and physical performance.

The application study of polycarboxylates water-reducing admixture in passenger dedicated line engineering

Polycarboxylate water-reducing admixture possesses the capability which could meet with the comprehensive performance of high performance concrete used in passenger dedicated line engineering.The problems of polycarboxylates water-reducing admixtures existed in the engineering application of were analyzed.At present the key for polycarboxylates application was to settle the compatibility between the water-reducing admixture and the cement and to keep the quality retention of this admixture.

Germline mutation analysis of MLH1 and MSH2 in Malaysian Lynch syndrome patients

AIM: To investigate the protein expression profi le of mismatch repair (MMR) genes in suspected cases of Lynch syndrome and to characterize the associated germline mutations. METHODS: Immunohistochemical analysis of tumor samples was performed to determine the protein expression profile of MMR protein. Germline mutation screening was carried out on peripheral blood samples. The entire exon regions of MLH1 and MSH2 geneswere amplifi ed by polymerase chain reaction, screened by denaturing high performance liquid chromatography (dHPLC) and analyzed by DNA sequencing to characterize the germline mutations. RESULTS: Three out of 34 tissue samples (8.8%) and four out of 34 tissue samples (11.8%) showed loss of nuclear staining by immunohistochemistry, indicating the absence of MLH1 and MSH2 protein expression in carcinoma cells, respectively. dHPLC analysis followed by DNA sequencing showed these samples to have germline mutations of MSH2 gene. However, no deleterious mutations were identifi ed in any of the 19 exons or coding regions of MLH1 gene, but we were able to identify MLH1 promoter polymorphism, -93G > A (rs1800734), in 21 out of 34 patients (61.8%). We identified one novel mutation, transversion mutation c.2005G > C, which resulted in a missense mutation (Gly669Arg), a transversion mutation in exon 1, c.142G > T, which resulted in a nonsense mutation (Glu48Stop) and splice-site mutation, c.2006-6T > C, which was adjacent to exon 13 of MSH2 gene. CONCLUSION: Germline mutations were identified in four Malaysian Lynch syndrome patients. Immunohistochemical analysis of tumor tissue proved to be a good pre-screening test before proceeding to germline mutation analysis of DNA MMR genes.

Changes in Plasma Angiotensin II and Circadian Rhythm of Blood Pressure in Hypertensive Patients with Sleep Apnea Syndrome Before and After Treatment

Objective To explore the changes in plasma angiotensin II （Ang Ⅱ） and circadian rhythm of blood pressure among hypertensive patients with sleep apnea syndrome （SAS） before and after continuous positive airway pressure （CPAP） or surgical treatment. Methods A total of 180 essential hypertension patients were enrolled in our study. The determination of plasma Ang Ⅱ concentration, ambulatory blood pressure （ABP）, and polysomnography （PSG） monitoring were performed before and 3 months after CPAP or surgical treatment. Results Patients were classified into three groups by their apnea-hypopnea index （AHI）： essential hypertension group （EH group, n=72; AHI〈5）, essential hypertension with mild SAS group （EH＋mild SAS group, n=60, 5≤AHI〈20）, and essential hypertension with moderate and severe SAS group （EH＋moderate-severe SAS group, n=48, AHI_〉20）. The concentrations of plasma AngⅡ in the above three groups were 13.42±3.27, 16.17±3.82, and 18.73±4.05 ng/mL respectively before treatment, and AngⅡ concentration in EH patients combined with SAS was significantly higher than that in EH group （all P〈0.05）. After treatment the values in the latter two groups significantly decreased to 14.67±2.56 and 15.03±3.41 ng/mL respectively （P〈0.05）. The incidence of non-dipper blood pressure curve in EH patients was 31.9%, and those in hypertensive patients with mild SAS and moderate-severe SAS were 51.7% and 58.3%, respectively before treatment. The incidence of non-dipper blood pressure curve in the EH patients with mild SAS was significantly higher than that of patients with EH alone （P〈0.05）. After CPAP treatment or surgery, the incidence of non-dipper blood pressure curve in the two SAS groups was significantly decreased to 38.3% and 39.6%, respectively （P〈0.05）. Conclusions Ang Ⅱ might play a role in blood pressure variability in patients with obstructive SAS. CPAP or surgical treatment can improve blood pressure disorder and decrease plasma Ang Ⅱ level in patients with obstructive SAS.

High resolution 3D nonlinear integrated inversion

The high resolution 3D nonlinear integrated inversion method is based on nonlinear theory. Under layer control, the log data from several wells （or all wells） in the study area and seismic trace data adjacent to the wells are input to a network with multiple inputs and outputs and are integratedly trained to obtain an adaptive weight function of the entire study area. Integrated nonlinear mapping relationships are built and updated by the lateral and vertical geologic variations of the reservoirs. Therefore, the inversion process and its inversion results can be constrained and controlled and a stable seismic inversion section with high resolution with velocity inversion, impedance inversion, and density inversion sections, can be gained. Good geologic effects have been obtained in model computation tests and real data processing, which verified that this method has high precision, good practicality, and can be used for quantitative reservoir analysis.

Rong Shuan Jiao Nang in the treatment of acute mountain sickness and high altitude myocardial ischemic syndrome in Yushu

To evaluate the therapeutic effects of Rong Shuan Jiao Nang （RSJN） on treatment of acute mountain sickness （AMS） and high altitude myocardial ischemic syndrome in workers in Yushu, three groups were studied： group A （60 patients with AMS, given RSJN）, group B （15 patients with altitude myocardial ischemic syndrome, given RSJN）, and group C （control, without drugs）. All studied subjects were lowland workers who were first time entry to Yushu for work at an altitude of 4 250 m. During the course of treatment, a routing physical examina- tion was performed, AMS Lake Louise Scores were estimated, arterial oxygen saturation （SaO2）, electrocardiography and hemoglobin concentration were measured before and after using RSJN for 10 days. In group A, the effective rate was 68 %, symptomatic improvement in 54 cases （90 %） within 5 days. In group B, the effective rate was 93 %, episodes of angina pectoris stopped in 12 patients within 3 - 7 days, one lasted 8 days. After treatment, the level of SaO2 increased 15.5 %, 21.8 % and 5.6 % in group A, group B and group C, respectively. RSJN tak- en at the start of the arrival at Yushu can decrease AMS scores and facilitate cure. If taken after the illness has begun, RSJN may help lessen symptoms, especially effectively improved angina pectoris of the high altitude myocardial ischemic syndrome. Symptoms usually subside after 3 - 8 days. RSJN should be continually used lbr at least 7 days after ascent.

The innovation of the ideological and political lesson＇s practical teaching model in colleges and universities

Strengthen the practical teaching is an important way to improve effectiveness of colleges＇ ideological and political lessons. It has an important role to stimulate the students＇ individuality development, cultivate students＇ innovative spirit, help students improve their ability of analyzing and solving problems, and improve students＇ comprehensive quality. This paper will analyze the problems existing in practical teaching model of ideological and political lessons, and put forward the corresponding reform measures, hoping to innovate and perfect the practical teaching model.

Study on Vaccination Efficacy against Avian Influenza in Rajshahi, Bangladesh

Vaccines are used in integrated control strategies to guard poultry against H5N1 high-pathogenicity avian influenza （AI）. This study was to evaluate the efficacy of AI vaccine against AI in poultry. About 400 serum samples were collected from the selected 130 farms located at Rajshahi region, Bangladesh. The study was carried out from January, 2013 to January, 2015. The AI vaccine titres were compared in different breed of layer, environmental temperature, feed and egg production. Result showed that the value of titres （mean ± SD） in Hyline brown, Hyline white, Bovans white and Novogen white were 6.71 ± 0.05, 6.67 ± 0.06, 6.79 ± 0.03 and 6.43 ± 0.04, respectively. The highest serum antibody titres were 6.61 ± 0.24 against AI antibody in 〉 26 ℃ environment temperature. The highest and lowest serum antibody value of AI against feed brand （nutrient） were 7.75 ± 0.08 and 5.58 ± 0.22 for Aftab and Quality brand feed, respectively.

Systematic review and meta analysis of randomized controlled trials on Tianmagouteng decoction in treatment of primary hypertension with liverYang hyperactivity syndrome

OBJECTIVE： To assess the efficacy of Tianma- gouteng decoction in the treatment of primary hypertension with liver yang hyperactivity syndrome. METHODS： The databases of MEDLINE （1950- 2012）, EMbase （1980-2012）, China biology medicine （CBM） （1994-2012）, China national knowledge infrastructure （CNKI） （1989-2012）, Weipu （VIP） （1995-2012） and Wanfang （1989-2012） were searched and we performed manual searches for conference proceedings to select randomized controlled trials （RCTs） on Tianmagouteng decoction for the treatment of primary hypertension with liver Yang hyperactivity syndrome. Studies were en- rolled according to the study-selecting criteria. The methodological quality was evaluated, data were extracted and meta-analyses were conducted with RevMan 4.2 software. RESULTS： Nine RCTs were selected involving 784 patients with no significant difference in decrease in systolic blood pressure （SBP）[0R=1.02, 9.5% CI （-0.24, 2.29）, P=0.10] and diastolic blood pressure（DBP） [OR=0.56, 95% CI （-0.10,1.23）, P=0.11] between the Tianmagouteng group and the control group. While there was a significantly larger increase in serum superoxide dismutase （SOD）[OR= 6.26, 95% CI （1.27,11.66）, P=0. 01] in the Tianmagouteng group than that in the control group CONCLUSION： Tianmagouteng decoction can decrease both systolic and diastolic blood pressure and greatly increase serum SOD. Due to poor quality of included studies, the efficacy needs to be further assessed.