Effect of Implanted Chip System on Blood Pressure Regulation in Rabbits

Objective: To evaluate the efficiency of an implanted chip system on blood pressure regulation. Methods: The mean arterial pressure (MAP) and heart rate (HR) were recorded in anesthetized rabbits. Based on the set point theory, an implanted chip system was designed to regulate the blood pressure by stimulating the aortic depressor nerve (ADN) according to the feedback of blood pressure. The blood pressure regulation induced by the implanted chip system was carried out twice (lasted for 15 min and 60 min respectively) and the change of MAP and HR during the regulation was compared with the control. Results: There was a significant decrease of MAP during the first regulation ([-32.0 ± 6.6] mmHg) and second regulation ([-27.4 ± 6.2] mmHg) compared with the control (P<0.01). The HR was also significantly decreased during regulation compared with the control. Both MAP and HR returned to the baseline immediately without rebound after the regulation ceased. Conclusion: The implanted chip system can regulate the blood pressure successfully and keep the blood pressure in a lower constant level without adaptation.

以吐治病话藜芦

在《本草纲目》藜芦条下记载着这样的故事:在金代,有一位妇女患风痫(癫痫)数十年未愈,此妇人是在六、七岁时因外感风寒而患惊风,迁延未愈,此后,每一、二年发作一次,并且是逐年增多,五至七年后每年发作5～7次,在妇人30～40岁时此病已是每日发作,严重时一日发作10余次。发作时病人往往突然昏倒,不省人事,项强直颈、牙关紧闭,口吐白沫,甚是痛苦。曾经四方求医诊治均未痊愈,此妇及其家人对该病治疗已无信心,早已放弃治疗,只求早死。刚好有一年闹饥荒,无粮可食。