目的:探讨颏下高频超声波(SUS)检查在儿童口咽期吞咽障碍评估中的价值。方法:选取20名口咽期吞咽障碍的儿童(8名依赖管饲进食,12名常规经口进食)和25名吞咽功能正常儿童,应用SUS测量吞咽5 m L水时舌肌厚度变化值和舌骨位移幅度。以经口...目的:探讨颏下高频超声波(SUS)检查在儿童口咽期吞咽障碍评估中的价值。方法:选取20名口咽期吞咽障碍的儿童(8名依赖管饲进食,12名常规经口进食)和25名吞咽功能正常儿童,应用SUS测量吞咽5 m L水时舌肌厚度变化值和舌骨位移幅度。以经口摄食功能量表(FOIS)评估结果为参照,绘制ROC,评估舌肌厚度变化值和舌骨位移幅度对管饲依赖性吞咽障碍的诊断效能。结果:口咽期吞咽障碍的儿童舌肌厚度变化值和舌骨位移幅度均大于正常儿童(P<0.05)。以舌肌厚度变化值诊断管饲依赖性吞咽障碍的ROC的AUC(95%CI)为0.853(0.689~1.000),诊断界值为0.95 cm时灵敏度和特异度分别为73.0%和87.5%,约登指数为0.605。以舌骨位移幅度诊断管饲依赖性吞咽障碍的ROC的AUC(95%CI)为0.829(0.609~1.000),诊断界值为1.35 cm时灵敏度和特异度分别为86.5%和75.0%,约登指数为0.615。结论:SUS检查能够辅助评估口咽期吞咽障碍儿童的吞咽功能。展开更多
Purpose To evaluate the long-term effects of intraoperative application of mitomycin C on the scleral thickness and the conjunctival epithelium at the surg ical site of pterygium excision.Design Prospective observatio...Purpose To evaluate the long-term effects of intraoperative application of mitomycin C on the scleral thickness and the conjunctival epithelium at the surg ical site of pterygium excision.Design Prospective observational case series.Participants Twenty-four patients who underwent excision of primary pterygiumwith intraoperative mitomycin C in our department during the year 1996.Methods Patients were evaluated by slit-lamp biomicroscopy,impression cytology,and high-frequency ultrasonograph y.Impression cytology was performed by applying a small nit rocellulose filter paper for a few seconds at the excision area and for a few seconds at the opposite perilimbal area,and subjecting the speci-mens to the periodic acid-Schiff-Gi ll modified Papanico-laou staining protocol.The morphology of the conjunctival epithelium and goblet cell density(GCD)-were record-ed.High-frequency ultrasound was p erformed at the same sites,and the scleral thickness was measured at a distance of 1mm from the limbus.Main outcome measures Goblet cell density,conjunetival epithelialmorphology,and the scleral thickness at the operated an d nonoperated sites. Results All patients had successful pterygium removal with no corneal recurrence after a mean fo llow-up of 77.2±3.9months(range,72-84).Impression cytology revealed normal nongoblet conjunctival epithelial cells at the excision area,with a 4-fold decrease in the GCD at the excision area when compared with the contrala teral nonoperated site(296±120cells /mm 2 and 1183±310cells /mm 2 ,re-spectively;P=0.0036).No differences were noted be-tween the scleral thicknesses at the operated site(750±70μm)and the opposite site(740±80μm)(P=0.84).Conclusions A single application of mitomyein C after pterygium excision is not associate d with reduction in sel-eral thickness more than 6years postoperatively.The eonjunetival epithelium retains its normal phenotype,with a marked reduction of the GCD.展开更多
文摘目的:探讨颏下高频超声波(SUS)检查在儿童口咽期吞咽障碍评估中的价值。方法:选取20名口咽期吞咽障碍的儿童(8名依赖管饲进食,12名常规经口进食)和25名吞咽功能正常儿童,应用SUS测量吞咽5 m L水时舌肌厚度变化值和舌骨位移幅度。以经口摄食功能量表(FOIS)评估结果为参照,绘制ROC,评估舌肌厚度变化值和舌骨位移幅度对管饲依赖性吞咽障碍的诊断效能。结果:口咽期吞咽障碍的儿童舌肌厚度变化值和舌骨位移幅度均大于正常儿童(P<0.05)。以舌肌厚度变化值诊断管饲依赖性吞咽障碍的ROC的AUC(95%CI)为0.853(0.689~1.000),诊断界值为0.95 cm时灵敏度和特异度分别为73.0%和87.5%,约登指数为0.605。以舌骨位移幅度诊断管饲依赖性吞咽障碍的ROC的AUC(95%CI)为0.829(0.609~1.000),诊断界值为1.35 cm时灵敏度和特异度分别为86.5%和75.0%,约登指数为0.615。结论:SUS检查能够辅助评估口咽期吞咽障碍儿童的吞咽功能。
文摘Purpose To evaluate the long-term effects of intraoperative application of mitomycin C on the scleral thickness and the conjunctival epithelium at the surg ical site of pterygium excision.Design Prospective observational case series.Participants Twenty-four patients who underwent excision of primary pterygiumwith intraoperative mitomycin C in our department during the year 1996.Methods Patients were evaluated by slit-lamp biomicroscopy,impression cytology,and high-frequency ultrasonograph y.Impression cytology was performed by applying a small nit rocellulose filter paper for a few seconds at the excision area and for a few seconds at the opposite perilimbal area,and subjecting the speci-mens to the periodic acid-Schiff-Gi ll modified Papanico-laou staining protocol.The morphology of the conjunctival epithelium and goblet cell density(GCD)-were record-ed.High-frequency ultrasound was p erformed at the same sites,and the scleral thickness was measured at a distance of 1mm from the limbus.Main outcome measures Goblet cell density,conjunetival epithelialmorphology,and the scleral thickness at the operated an d nonoperated sites. Results All patients had successful pterygium removal with no corneal recurrence after a mean fo llow-up of 77.2±3.9months(range,72-84).Impression cytology revealed normal nongoblet conjunctival epithelial cells at the excision area,with a 4-fold decrease in the GCD at the excision area when compared with the contrala teral nonoperated site(296±120cells /mm 2 and 1183±310cells /mm 2 ,re-spectively;P=0.0036).No differences were noted be-tween the scleral thicknesses at the operated site(750±70μm)and the opposite site(740±80μm)(P=0.84).Conclusions A single application of mitomyein C after pterygium excision is not associate d with reduction in sel-eral thickness more than 6years postoperatively.The eonjunetival epithelium retains its normal phenotype,with a marked reduction of the GCD.
