The repeated DNA in the genomes of three fish species (Dario rerio, Monopterus albus and Mastacembelus aculeatus), were compared with those in human Y chromosome-specific heterochromatin by genomic comparative in situ...The repeated DNA in the genomes of three fish species (Dario rerio, Monopterus albus and Mastacembelus aculeatus), were compared with those in human Y chromosome-specific heterochromatin by genomic comparative in situ hybridization.The results showed that the repeated DNA in the genomes of three fish species could not hybridize with those in human Y chromosome-specific heterochromatin region and the human Y chromosome had its specific repeated DNA sequence.Some problems about the evolution of the repeated DNA in human Y chromosome-specific heterochromatin region were discussed.展开更多
Aquaculture is one of the fastest developing agricultural industries worldwide.One of the most important factors for sustainable aquaculture is the development of high performing culture strains.Genome manipulation of...Aquaculture is one of the fastest developing agricultural industries worldwide.One of the most important factors for sustainable aquaculture is the development of high performing culture strains.Genome manipulation offers a powerful method to achieve rapid and directional breeding in fish.We review the history of fish breeding methods based on classical genome manipulation,including polyploidy breeding and nuclear transfer.Then,we discuss the advances and applications of fish directional breeding based on transgenic technology and recently developed genome editing technologies.These methods offer increased efficiency,precision and predictability in genetic improvement over traditional methods.展开更多
The traits of cultured fish must continually be genetically improved to supply high-quality animal protein for human consumption.Economically important fish traits are controlled by multiple gene quantitative trait lo...The traits of cultured fish must continually be genetically improved to supply high-quality animal protein for human consumption.Economically important fish traits are controlled by multiple gene quantitative trait loci(QTL),most of which have minor effects,but a few genes may have major effects useful for molecular breeding.In this review,we chose relevant studies on some of the most intensively cultured fish and concisely summarize progress on identifying and verifying QTLs for such traits as growth,disease and stress resistance and sex in recent decades.The potential applications of these major-effect genes and their associated markers in marker-assisted selection and molecular breeding,as well as future research directions are also discussed.These genetic and genomic analyses will be valuable for elucidating the mechanisms modulating economically important traits and to establish more effective molecular breeding techniques in fish.展开更多
文摘The repeated DNA in the genomes of three fish species (Dario rerio, Monopterus albus and Mastacembelus aculeatus), were compared with those in human Y chromosome-specific heterochromatin by genomic comparative in situ hybridization.The results showed that the repeated DNA in the genomes of three fish species could not hybridize with those in human Y chromosome-specific heterochromatin region and the human Y chromosome had its specific repeated DNA sequence.Some problems about the evolution of the repeated DNA in human Y chromosome-specific heterochromatin region were discussed.
基金supported by the National Basic Research Program of China(2010CB126306,2012CB944504)the National Science Fund for Excellent Young Scholars of the National Natural Science Foundation of China(31222052)+1 种基金the Chinese Academy of Sciences Grant KSCX2-EW-N-004-4the State Key Laboratory of Freshwater Ecology and Biotechnology grant 2011FBZ23
文摘Aquaculture is one of the fastest developing agricultural industries worldwide.One of the most important factors for sustainable aquaculture is the development of high performing culture strains.Genome manipulation offers a powerful method to achieve rapid and directional breeding in fish.We review the history of fish breeding methods based on classical genome manipulation,including polyploidy breeding and nuclear transfer.Then,we discuss the advances and applications of fish directional breeding based on transgenic technology and recently developed genome editing technologies.These methods offer increased efficiency,precision and predictability in genetic improvement over traditional methods.
基金supported by the National Basic Research Program of China(2010CB126305)
文摘The traits of cultured fish must continually be genetically improved to supply high-quality animal protein for human consumption.Economically important fish traits are controlled by multiple gene quantitative trait loci(QTL),most of which have minor effects,but a few genes may have major effects useful for molecular breeding.In this review,we chose relevant studies on some of the most intensively cultured fish and concisely summarize progress on identifying and verifying QTLs for such traits as growth,disease and stress resistance and sex in recent decades.The potential applications of these major-effect genes and their associated markers in marker-assisted selection and molecular breeding,as well as future research directions are also discussed.These genetic and genomic analyses will be valuable for elucidating the mechanisms modulating economically important traits and to establish more effective molecular breeding techniques in fish.
