Objective The research aimed to provide theoretical basis for studying anti-MDV mechanism of ginsenoside and its derivatives in vitro. Method Effects of ginsenoside and its derivatives on proliferation activity of c...Objective The research aimed to provide theoretical basis for studying anti-MDV mechanism of ginsenoside and its derivatives in vitro. Method Effects of ginsenoside and its derivatives on proliferation activity of chick embryo fibroblast （CEF） in vitro were determined by using neutral red dye absorption method. Result The results showed the proliferation effects of different drugs are not completely same, and are more obvious with low toxic drugs. Detected at different action times, the differences of OD values was biggest at 72 h when compared with normal control group, while there was no significant difference at 24 h. Conclusion Ginsenoside and its derivatives could promote the proliferation of CEF cells in medium as low concentrations, which have time-dependent characteristic.展开更多
基金Supported by the National Natural Science Foundation of China(No.30471272)~~
文摘Objective The research aimed to provide theoretical basis for studying anti-MDV mechanism of ginsenoside and its derivatives in vitro. Method Effects of ginsenoside and its derivatives on proliferation activity of chick embryo fibroblast （CEF） in vitro were determined by using neutral red dye absorption method. Result The results showed the proliferation effects of different drugs are not completely same, and are more obvious with low toxic drugs. Detected at different action times, the differences of OD values was biggest at 72 h when compared with normal control group, while there was no significant difference at 24 h. Conclusion Ginsenoside and its derivatives could promote the proliferation of CEF cells in medium as low concentrations, which have time-dependent characteristic.
