Thyroid hormone deficiency was created artificially in chick embryos by injecting propyl-thiouracil (PTU).The tubulin was quantified by ~3H-colchicine assay(expressed as colchicine binding activity).Thyroid hormone de...Thyroid hormone deficiency was created artificially in chick embryos by injecting propyl-thiouracil (PTU).The tubulin was quantified by ~3H-colchicine assay(expressed as colchicine binding activity).Thyroid hormone deficiency resulted in 16％ to 28％ decline of the tubulin level in the developing chick brain from 15 to 19 days of embryonic age as compared with the control,whereas the total protein amount was not significantly affected.It suggests that thyroid hormone specifically affected the synthesis of brain tubulin.展开更多
文摘Thyroid hormone deficiency was created artificially in chick embryos by injecting propyl-thiouracil (PTU).The tubulin was quantified by ~3H-colchicine assay(expressed as colchicine binding activity).Thyroid hormone deficiency resulted in 16％ to 28％ decline of the tubulin level in the developing chick brain from 15 to 19 days of embryonic age as compared with the control,whereas the total protein amount was not significantly affected.It suggests that thyroid hormone specifically affected the synthesis of brain tubulin.
