Background:To report the occurrence of a full thickness macular hole in association with idiopathic parafoveal telangiectasia.Methods:Observational case report.Results:A 60-year-old female with a history of bilateral ...Background:To report the occurrence of a full thickness macular hole in association with idiopathic parafoveal telangiectasia.Methods:Observational case report.Results:A 60-year-old female with a history of bilateral idiopathic parafoveal telangiectasia presented with acute complaints of decreased vision and metamorphopsia in her right eye.The patient’s retinal examination was significant for idiopathic parafoveal telangiectasia bilaterally,and a new,full-thickness macular hole in the right eye which was confirmed by optical coherence tomography.Conclusions:Full-thickness macular hole formation may occur in conjunction with idiopathic parafoveal telangiectasia,which has not been reported to date.Idiopathic parafoveal telangiectasia,IPT,is a clinical entity with distinct biomicroscopic and fluorescein angiographic findings which may be divided into developmental and acquired forms.Idiopathic macular hole formation is a relatively common condition,which tends to occur more frequently in females in their 7th and 8th decades of life.Idiopathic parafoveal telangiectasia has been reported in association with lamellar macular holes,but,to our knowledge,not with a full thickness macular hole.Here in we report the case of a patient with bilateral idiopathic parafoveal telangiectasia who developed a full-thickness macular hole.展开更多
To report combined treatment of photodynamic therapy (PDT) with verteporfin an d intravitreal triamcinolone acetonide injection for subfoveal neovascularizatio n secondary to bilateral idiopathic juxtafoveal telangiec...To report combined treatment of photodynamic therapy (PDT) with verteporfin an d intravitreal triamcinolone acetonide injection for subfoveal neovascularizatio n secondary to bilateral idiopathic juxtafoveal telangiectasis. Interventional c ase report. A patient with a subfoveal neovascularization secondary to bilateral idiopathic juxtafoveal telangiectasis was treated with PDT plus an intravitreal injection of 4 mg of triamcinolone acetonide. Leakage in the late phase of flu orescein angiography resolved with attenuation of telangiectatic vessels and imp rovement in visual acuity from 20/200 to 20/50. At 9 months post treatment, rec urrent leakage was treated with repeat PDT and intravitreal triamcinolone. One y ear after initial presentation, visual acuity was 20/60 with no leakage on fluor escein. Combined treatment with PDT and intravitreal triamcinolone acetonide res ulted in regression of a subfoveal neovascular membrane and improvement in visua l acuity during the course of follow up.展开更多
Objective: To investigate the capabilities of ultrahighreso-lution optical coherence tomography (UHR OCT); to compare with the commercially available OCT standard-resolution system, StratusOCT, for imaging of idiopath...Objective: To investigate the capabilities of ultrahighreso-lution optical coherence tomography (UHR OCT); to compare with the commercially available OCT standard-resolution system, StratusOCT, for imaging of idiopathic juxtafoveal retinal telangiectasis (IJT); and to demonstrate that UHROCT provides additional information on disease morphology, pathogenesis, and management. Design: Retrospective, observational, interventional case series. Participants: Nineteen eyes of 10 patients diagnosed with IJT in at least one eye. Method: All patients were imaged with UHR OCT and StratusOCT at the same visit. A subset of patients was also imaged before and after treatment of IJT. Main Outcome Measures: Ultrahigh-and standard-resolution cross-sectional tomograms of IJT pathology. Results: Using both standard-and ultrahigh-resolution OCT, we identified the following features of IJT: (1) a lack of correlation between retinal thickening on OCT and leakage on fluorescein angiography, (2) loss and disruption of the photoreceptor layer, (3) cystlike structures in the foveola and within internal retinal layers such as the inner nuclear or ganglion cell layers, (4) a unique internal limiting membrane draping across the foveola related to an underlying loss of tissue, (5) intraretinal neovascularization near the fovea, and (6) central intraretinal deposits and plaques. In 63%of cases, the presence of abnormal vessels and a discontinuity of the photoreceptor layer correlatedwith visual acuity. Conclusions: Ultrahigh-resolution OCT improves visualization of the retinal pathology associated with IJT and allows identification of new features associated with it. Some of these features, such as discontinuity of the photoreceptor layer, are revealed only by UHR OCT.展开更多
文摘Background:To report the occurrence of a full thickness macular hole in association with idiopathic parafoveal telangiectasia.Methods:Observational case report.Results:A 60-year-old female with a history of bilateral idiopathic parafoveal telangiectasia presented with acute complaints of decreased vision and metamorphopsia in her right eye.The patient’s retinal examination was significant for idiopathic parafoveal telangiectasia bilaterally,and a new,full-thickness macular hole in the right eye which was confirmed by optical coherence tomography.Conclusions:Full-thickness macular hole formation may occur in conjunction with idiopathic parafoveal telangiectasia,which has not been reported to date.Idiopathic parafoveal telangiectasia,IPT,is a clinical entity with distinct biomicroscopic and fluorescein angiographic findings which may be divided into developmental and acquired forms.Idiopathic macular hole formation is a relatively common condition,which tends to occur more frequently in females in their 7th and 8th decades of life.Idiopathic parafoveal telangiectasia has been reported in association with lamellar macular holes,but,to our knowledge,not with a full thickness macular hole.Here in we report the case of a patient with bilateral idiopathic parafoveal telangiectasia who developed a full-thickness macular hole.
文摘To report combined treatment of photodynamic therapy (PDT) with verteporfin an d intravitreal triamcinolone acetonide injection for subfoveal neovascularizatio n secondary to bilateral idiopathic juxtafoveal telangiectasis. Interventional c ase report. A patient with a subfoveal neovascularization secondary to bilateral idiopathic juxtafoveal telangiectasis was treated with PDT plus an intravitreal injection of 4 mg of triamcinolone acetonide. Leakage in the late phase of flu orescein angiography resolved with attenuation of telangiectatic vessels and imp rovement in visual acuity from 20/200 to 20/50. At 9 months post treatment, rec urrent leakage was treated with repeat PDT and intravitreal triamcinolone. One y ear after initial presentation, visual acuity was 20/60 with no leakage on fluor escein. Combined treatment with PDT and intravitreal triamcinolone acetonide res ulted in regression of a subfoveal neovascular membrane and improvement in visua l acuity during the course of follow up.
文摘Objective: To investigate the capabilities of ultrahighreso-lution optical coherence tomography (UHR OCT); to compare with the commercially available OCT standard-resolution system, StratusOCT, for imaging of idiopathic juxtafoveal retinal telangiectasis (IJT); and to demonstrate that UHROCT provides additional information on disease morphology, pathogenesis, and management. Design: Retrospective, observational, interventional case series. Participants: Nineteen eyes of 10 patients diagnosed with IJT in at least one eye. Method: All patients were imaged with UHR OCT and StratusOCT at the same visit. A subset of patients was also imaged before and after treatment of IJT. Main Outcome Measures: Ultrahigh-and standard-resolution cross-sectional tomograms of IJT pathology. Results: Using both standard-and ultrahigh-resolution OCT, we identified the following features of IJT: (1) a lack of correlation between retinal thickening on OCT and leakage on fluorescein angiography, (2) loss and disruption of the photoreceptor layer, (3) cystlike structures in the foveola and within internal retinal layers such as the inner nuclear or ganglion cell layers, (4) a unique internal limiting membrane draping across the foveola related to an underlying loss of tissue, (5) intraretinal neovascularization near the fovea, and (6) central intraretinal deposits and plaques. In 63%of cases, the presence of abnormal vessels and a discontinuity of the photoreceptor layer correlatedwith visual acuity. Conclusions: Ultrahigh-resolution OCT improves visualization of the retinal pathology associated with IJT and allows identification of new features associated with it. Some of these features, such as discontinuity of the photoreceptor layer, are revealed only by UHR OCT.
