Chemical constituents of the whole herb of Bidens pilosa L. were investigated. By using various column chromatography (CC) and spectroscopic methods, 13 flavonoids were isolated and identified as follows: 2′-hydro...Chemical constituents of the whole herb of Bidens pilosa L. were investigated. By using various column chromatography (CC) and spectroscopic methods, 13 flavonoids were isolated and identified as follows: 2′-hydroxy-4,4′-dimethoxy-chalcone (1), isoliquiritigenin (2), 3,2′,4′-trihydroxy-4-methoxy-chalcone (3), licochalcone A (4),4′-O-β-D-glucopyranosyl-2′,3-dihydroxy-4-methoxy-chalcone (5), butein (6), apigenin (7), luteolin (8), diosmetin (9), chrysoeriol (10), 3,5,6,7,3′,4′,5′-heptamethoxyflavone (11), 7-O-β-D-glucopyranosyt-5,3′dihydroxy-3,6,4′-trimethoxyfiavone (12), sulfuretin (13). Compounds 1-5, 9, 11 were obtained from the genus Bidens for the first time.展开更多
基金Research Platform for Quality Standard of TCM and Information System Building(Grant No.2009ZX09308-04)National S&T Major Project-Created Major New Drugs Projects (Grant No.2009ZX09311-004)
文摘Chemical constituents of the whole herb of Bidens pilosa L. were investigated. By using various column chromatography (CC) and spectroscopic methods, 13 flavonoids were isolated and identified as follows: 2′-hydroxy-4,4′-dimethoxy-chalcone (1), isoliquiritigenin (2), 3,2′,4′-trihydroxy-4-methoxy-chalcone (3), licochalcone A (4),4′-O-β-D-glucopyranosyl-2′,3-dihydroxy-4-methoxy-chalcone (5), butein (6), apigenin (7), luteolin (8), diosmetin (9), chrysoeriol (10), 3,5,6,7,3′,4′,5′-heptamethoxyflavone (11), 7-O-β-D-glucopyranosyt-5,3′dihydroxy-3,6,4′-trimethoxyfiavone (12), sulfuretin (13). Compounds 1-5, 9, 11 were obtained from the genus Bidens for the first time.