In the present paper, the ethyl acetate extract from the fruiting bodies of Tirmania pinoyi （Maire） was obtained by Soxhlet extraction. Six fractions were separated from this extract using two chromatographic method...In the present paper, the ethyl acetate extract from the fruiting bodies of Tirmania pinoyi （Maire） was obtained by Soxhlet extraction. Six fractions were separated from this extract using two chromatographic methods. All these fractions were submitted to antimicrobial activity against four clinically important bacteria Staphylococcus aureus ATCC6538, Enterococcusfaecalis ATCC6538 Pseudomonas aeruginosa ATCC14028, Escherichia coli ATCC25922 and one pathogenic fungus Candida albicans ATCCI0231. The in vitro antimicrobial activity was performed by agar disc diffusion method. The fractions with the greatest antimicrobial activity were fractions 02 and 06 which inhibited growth of both Gram negative and Gram positive bacteria and had significant antifungal activity against Candida albicans. The present study validates the folk use of the boiled truffle water-extract and indicates that it could be effective potential candidates for the development of new strategies to treat bacterial or fungal infections.展开更多
文摘In the present paper, the ethyl acetate extract from the fruiting bodies of Tirmania pinoyi （Maire） was obtained by Soxhlet extraction. Six fractions were separated from this extract using two chromatographic methods. All these fractions were submitted to antimicrobial activity against four clinically important bacteria Staphylococcus aureus ATCC6538, Enterococcusfaecalis ATCC6538 Pseudomonas aeruginosa ATCC14028, Escherichia coli ATCC25922 and one pathogenic fungus Candida albicans ATCCI0231. The in vitro antimicrobial activity was performed by agar disc diffusion method. The fractions with the greatest antimicrobial activity were fractions 02 and 06 which inhibited growth of both Gram negative and Gram positive bacteria and had significant antifungal activity against Candida albicans. The present study validates the folk use of the boiled truffle water-extract and indicates that it could be effective potential candidates for the development of new strategies to treat bacterial or fungal infections.
