Magnetic resonance imaging (MRI) findings in three patients with primary anorectal malignant melanoma are described. Two patients had melanotic and one had amelanotic anorectal melanoma. The findings of MRI with a pel...Magnetic resonance imaging (MRI) findings in three patients with primary anorectal malignant melanoma are described. Two patients had melanotic and one had amelanotic anorectal melanoma. The findings of MRI with a pelvic coil and an endorectal coil were consistent with pathologic findings. MRI with a pelvic coil demonstrated the melanotic component as high signal intensity on T1-weighted imaging. MRI with a pelvic coil and an endorectal coil was useful for staging anorectal melanoma. This article describes the initial report of the use of an endorectal coil for malignant melanoma of the anorectum.展开更多
Objective To report the spectrum and frequency of melanocytic and nonmelanocyt ic conjunctival tumors in an ocular oncology practice. Design Retrospective noninterventional case series. Participants One thousand six h...Objective To report the spectrum and frequency of melanocytic and nonmelanocyt ic conjunctival tumors in an ocular oncology practice. Design Retrospective noninterventional case series. Participants One thousand six hundred forty-three consecutive patients with a c onjunctival mass evaluated at an ocular oncology department. Methods A chart rev iew was conducted to obtain the clinical features of the patient and tumor and t o tabulate and categorize the diagnoses. Main outcome measures Tumor diagnosis o verall and relative to patient age, race, and gender and relative to tumor locat ion and laterality. Results In 1643 consecutive patients, the tumor was classifi ed as melanocytic in 872 cases (53%) and nonmelanocytic in 771 cases (47%). Th e nonmelanocytic categories included congenital choristomatous (n=40 2%), epi thelial (n=219 13%), vascular (n=63 4%), fibrous (n=7 < 1%), neural (n= 1 < 1%), xanthomatous (n=1 < 1%), myxomatous (n=1 < 1%), lipomatous (n=2 3 1%), lacrimal gland origin (n=12 < 1%), lymphoid (n=128 8%), leukemic (n=3 < 1%), metastatic (n=13 < 1%), secondary (n=54 3%) tumors, and no n-neoplastic lesions simulating a tumor (n=206 13%). Of the 872 melanocytic lesions, the specific tumor diagnosis was nevus in 454 cases (52%), melanoma in 215 (25%), and primary acquired melanosis in 180 (21%). Patients with chorist omatous, vascular, fibrous, xanthomatous, and myxomatous tumors presented at a m ean age of< 40 years, and those with malignant epithelial, lipomatous, leukemic, and secondary tumors presented at a mean age of >60. Of the 219 patients with e pithelial tumors, 80%occurred inmales, whereas the incidence of melanocytic les ions was equal in males and females. African-American patients represented only 7%of epithelial tumors,< 1%of melanomas, and 8%of lymphoid tumors. Conclusio n Conjunctival tumors were of melanocytic origin in 53%of cases and nonmelanocy tic origin in 47%. Overall, melanocytic tumors, epithelial tumors, and lymphoid tumors accounted for 74%of all cases. These tumors were far more common in Cau casian patients, and epithelial tumors were found more frequently in men.展开更多
文摘Magnetic resonance imaging (MRI) findings in three patients with primary anorectal malignant melanoma are described. Two patients had melanotic and one had amelanotic anorectal melanoma. The findings of MRI with a pelvic coil and an endorectal coil were consistent with pathologic findings. MRI with a pelvic coil demonstrated the melanotic component as high signal intensity on T1-weighted imaging. MRI with a pelvic coil and an endorectal coil was useful for staging anorectal melanoma. This article describes the initial report of the use of an endorectal coil for malignant melanoma of the anorectum.
文摘Objective To report the spectrum and frequency of melanocytic and nonmelanocyt ic conjunctival tumors in an ocular oncology practice. Design Retrospective noninterventional case series. Participants One thousand six hundred forty-three consecutive patients with a c onjunctival mass evaluated at an ocular oncology department. Methods A chart rev iew was conducted to obtain the clinical features of the patient and tumor and t o tabulate and categorize the diagnoses. Main outcome measures Tumor diagnosis o verall and relative to patient age, race, and gender and relative to tumor locat ion and laterality. Results In 1643 consecutive patients, the tumor was classifi ed as melanocytic in 872 cases (53%) and nonmelanocytic in 771 cases (47%). Th e nonmelanocytic categories included congenital choristomatous (n=40 2%), epi thelial (n=219 13%), vascular (n=63 4%), fibrous (n=7 < 1%), neural (n= 1 < 1%), xanthomatous (n=1 < 1%), myxomatous (n=1 < 1%), lipomatous (n=2 3 1%), lacrimal gland origin (n=12 < 1%), lymphoid (n=128 8%), leukemic (n=3 < 1%), metastatic (n=13 < 1%), secondary (n=54 3%) tumors, and no n-neoplastic lesions simulating a tumor (n=206 13%). Of the 872 melanocytic lesions, the specific tumor diagnosis was nevus in 454 cases (52%), melanoma in 215 (25%), and primary acquired melanosis in 180 (21%). Patients with chorist omatous, vascular, fibrous, xanthomatous, and myxomatous tumors presented at a m ean age of< 40 years, and those with malignant epithelial, lipomatous, leukemic, and secondary tumors presented at a mean age of >60. Of the 219 patients with e pithelial tumors, 80%occurred inmales, whereas the incidence of melanocytic les ions was equal in males and females. African-American patients represented only 7%of epithelial tumors,< 1%of melanomas, and 8%of lymphoid tumors. Conclusio n Conjunctival tumors were of melanocytic origin in 53%of cases and nonmelanocy tic origin in 47%. Overall, melanocytic tumors, epithelial tumors, and lymphoid tumors accounted for 74%of all cases. These tumors were far more common in Cau casian patients, and epithelial tumors were found more frequently in men.
