Objective To explore the feasibility of electroacupuncture compound anesthesia in radiofrequency ablation for hypertrophic inferior turbinate.Methods The patients confirmed to the enrolled criteria were randomly divid...Objective To explore the feasibility of electroacupuncture compound anesthesia in radiofrequency ablation for hypertrophic inferior turbinate.Methods The patients confirmed to the enrolled criteria were randomly divided into an observation group(n=31) and a control group(n=30).In the observation group,electroacupuncture was applied to Sìbái(四白 ST 2),Xiàguān(下关 ST 7),Hégǔ(合谷 LI 4) and Zhīgōu(支沟 TE 6) on the left side for the anesthesia and the routine local anesthesia was done on the right side.In the control group,the routine local anesthesia was adopted on both sides.The feelings of pain,circulatory index and operation effect were observed and compared between the two groups.Results During radiofrequency ablation,the pain grades of two measurements on the left side and the 2nd measurement on the right in the observation group were all lower than those in the control group(all P〈0.05).In the observation group,the pain grade on the left side was lower than that on the right side(P〈0.05),and the systolic blood pressure and the heart rate were lower than those in the control group when undergoing the 2nd radiofrequency ablation on the right side and on the left side,respectively(all P〈0.05).There was no significant difference in operation effect between the two groups.Conclusion Electroacupuncture compound anesthesia can meet the analgesia requirement of radiofrequency ablation for hypertrophic inferior turbinate,and would be helpful to prevent cyclic fluctuation during the operation at the same time.展开更多
Objective: To investigate effects of different treatment on celiac mast cell degranulation in mice with allergic rhinitis induced with ovum albumin (OVA). Methods: 60 female mice were randomly divided into five gr...Objective: To investigate effects of different treatment on celiac mast cell degranulation in mice with allergic rhinitis induced with ovum albumin (OVA). Methods: 60 female mice were randomly divided into five groups, 12 mice in each, which were treated with different methods. Then, the celiac mast cells were separated and degranulation rate was calculated after stained with neutral red. Results: the rates of mast cell degranulation were (15±6)%, (53±11)%, (37±13)%, (31±15)%, and (47±14)% in normal group, OVA group, point application group, hormone group, and PBS group. There is obvious degranulation in the celiac mast cells of mice with OVA-induced allergic rhinitis. Point application and dexamethasone treatment could relieve the mast cell degranulation, whereas, PBS has no effect on the mast cell degranulation. Conclusion: the mechanism of antianaphylaxis of point application may lie on stabilizing the mast cell membrane, and inhibiting degranulation to reduce the inflammatory mediator.展开更多
Objective:To observe the clinical efficacy of Zhen'ai needling method in Nei Jing(Classic of Internal Medicine)for children with allergic rhinitis(AR)accompanied by adenoid hypertrophy(AH).Methods:A total of 74 ch...Objective:To observe the clinical efficacy of Zhen'ai needling method in Nei Jing(Classic of Internal Medicine)for children with allergic rhinitis(AR)accompanied by adenoid hypertrophy(AH).Methods:A total of 74 children who met the screening criteria were divided into a Zhen'ai group and a control group by the random number table method,with 37 cases in each group.The control group was treated with acupuncture at Zusanli(ST 36),Hegu(LI 4),Yingxiang(LI 20),Juliao(ST 3),Yintang(GV 29),Shangxing(GV 23)and Baihui(GV 20).The Zhen'ai group added points of Zhen'ai needling method{Shanglianquan[Extra,located at 1 cun above Lianquan(CV 23)],Tianrong(SI 17)and Lieque(LU 7)}in addition to the points in the control group.The needles were retained for 30 min.The treatment was performed twice a week.The total nasal symptom score(TNSS),sino-nasal outcome test-20(SNOT-20)and symptom scale for AH(SSAH)were assessed before and after 10 treatments.The clinical efficacy of the two groups was compared after treatment.Results:During the treatment,5 cases dropped out in the control group and 2 cases in the Zhen'ai group.After treatment,the total effective rate of the Zhen'ai group was 94.3%,versus 93.8%in the control group.There was no significant difference between the two groups(P>0.05).The markedly effective rate of the Zhen'ai group was 42.9%,versus 12.5%in the control group,and the difference was statistically significant(P<0.05).After treatment,there were significant intra-group differences in the scores of TNSS,SNOT-20 and SSAH in both groups(all P<0.05);the scores of SNOT-20 and SSAH in the Zhen'ai group were lower than those in the control group,and the differences between the groups were statistically significant(both P<0.05).Conclusion:Both conventional acupuncture and conventional acupuncture plus Zhen'ai needling method can improve clinical symptoms of children with AR accompanied by AH;and conventional acupuncture plus Zhen'ai needling method has a better effect than conventional acupuncture in improving AH symptoms.展开更多
基金Supported by Foundation Project in Guang'anmen Hospital,China Academy of Chinese Medical Sciences:2006 S 195
文摘Objective To explore the feasibility of electroacupuncture compound anesthesia in radiofrequency ablation for hypertrophic inferior turbinate.Methods The patients confirmed to the enrolled criteria were randomly divided into an observation group(n=31) and a control group(n=30).In the observation group,electroacupuncture was applied to Sìbái(四白 ST 2),Xiàguān(下关 ST 7),Hégǔ(合谷 LI 4) and Zhīgōu(支沟 TE 6) on the left side for the anesthesia and the routine local anesthesia was done on the right side.In the control group,the routine local anesthesia was adopted on both sides.The feelings of pain,circulatory index and operation effect were observed and compared between the two groups.Results During radiofrequency ablation,the pain grades of two measurements on the left side and the 2nd measurement on the right in the observation group were all lower than those in the control group(all P〈0.05).In the observation group,the pain grade on the left side was lower than that on the right side(P〈0.05),and the systolic blood pressure and the heart rate were lower than those in the control group when undergoing the 2nd radiofrequency ablation on the right side and on the left side,respectively(all P〈0.05).There was no significant difference in operation effect between the two groups.Conclusion Electroacupuncture compound anesthesia can meet the analgesia requirement of radiofrequency ablation for hypertrophic inferior turbinate,and would be helpful to prevent cyclic fluctuation during the operation at the same time.
文摘Objective: To investigate effects of different treatment on celiac mast cell degranulation in mice with allergic rhinitis induced with ovum albumin (OVA). Methods: 60 female mice were randomly divided into five groups, 12 mice in each, which were treated with different methods. Then, the celiac mast cells were separated and degranulation rate was calculated after stained with neutral red. Results: the rates of mast cell degranulation were (15±6)%, (53±11)%, (37±13)%, (31±15)%, and (47±14)% in normal group, OVA group, point application group, hormone group, and PBS group. There is obvious degranulation in the celiac mast cells of mice with OVA-induced allergic rhinitis. Point application and dexamethasone treatment could relieve the mast cell degranulation, whereas, PBS has no effect on the mast cell degranulation. Conclusion: the mechanism of antianaphylaxis of point application may lie on stabilizing the mast cell membrane, and inhibiting degranulation to reduce the inflammatory mediator.
文摘Objective:To observe the clinical efficacy of Zhen'ai needling method in Nei Jing(Classic of Internal Medicine)for children with allergic rhinitis(AR)accompanied by adenoid hypertrophy(AH).Methods:A total of 74 children who met the screening criteria were divided into a Zhen'ai group and a control group by the random number table method,with 37 cases in each group.The control group was treated with acupuncture at Zusanli(ST 36),Hegu(LI 4),Yingxiang(LI 20),Juliao(ST 3),Yintang(GV 29),Shangxing(GV 23)and Baihui(GV 20).The Zhen'ai group added points of Zhen'ai needling method{Shanglianquan[Extra,located at 1 cun above Lianquan(CV 23)],Tianrong(SI 17)and Lieque(LU 7)}in addition to the points in the control group.The needles were retained for 30 min.The treatment was performed twice a week.The total nasal symptom score(TNSS),sino-nasal outcome test-20(SNOT-20)and symptom scale for AH(SSAH)were assessed before and after 10 treatments.The clinical efficacy of the two groups was compared after treatment.Results:During the treatment,5 cases dropped out in the control group and 2 cases in the Zhen'ai group.After treatment,the total effective rate of the Zhen'ai group was 94.3%,versus 93.8%in the control group.There was no significant difference between the two groups(P>0.05).The markedly effective rate of the Zhen'ai group was 42.9%,versus 12.5%in the control group,and the difference was statistically significant(P<0.05).After treatment,there were significant intra-group differences in the scores of TNSS,SNOT-20 and SSAH in both groups(all P<0.05);the scores of SNOT-20 and SSAH in the Zhen'ai group were lower than those in the control group,and the differences between the groups were statistically significant(both P<0.05).Conclusion:Both conventional acupuncture and conventional acupuncture plus Zhen'ai needling method can improve clinical symptoms of children with AR accompanied by AH;and conventional acupuncture plus Zhen'ai needling method has a better effect than conventional acupuncture in improving AH symptoms.