AIM： To compare the combination of fluorometholone0.1% and levofloxacin 0.5% to tobramycin/dexamethasone eye drops in controlling inflammation and preventing infection after phacoemulsification with an intraocular le...AIM： To compare the combination of fluorometholone0.1% and levofloxacin 0.5% to tobramycin/dexamethasone eye drops in controlling inflammation and preventing infection after phacoemulsification with an intraocular lens implantation.METHODS： Sixty eyes from 60 patients undergoing cataract phacoemulsification were randomized into two groups; half of the patients were treated with fluorometholone（6 times/d） combined with levofloxacin（4 times/d）, while the other half were treated with tobramycin/dexamethasone（4 times/d） eye drops for one week. Preoperative and postoperative intraocular pressure, aqueous flare, corneal thickness, and signs and symptoms were recorded before the operation and1 wk following treatments. RESULTS： There were no statistically significant differences between the two groups in corneal thickness（P ≥0.629）, aqueous flare（P ≥0.398）, and signs and symptoms scores（P ≥0.350） at each time point. Ocular hypertension was only observed in two eyes in the tobramycin/dexamethasone group. CONCLUSION： Fluorometholone combined with levofloxacin treatment shows comparable efficacy but without the tendency to increase intraocular pressure;thus, it might be a better regimen for postoperative use.展开更多
目的:探讨准分子激光角膜原位磨镶术(Laser in situ keratomileusis,LASIK)术后分别使用典必殊及氟美童滴眼液,术后1周、2周、1月、3月眼压的变化。方法:180例(360只眼)近视眼患者,进行LASIK手术,术后分成典必殊和氟美童两个组各90例(18...目的:探讨准分子激光角膜原位磨镶术(Laser in situ keratomileusis,LASIK)术后分别使用典必殊及氟美童滴眼液,术后1周、2周、1月、3月眼压的变化。方法:180例(360只眼)近视眼患者,进行LASIK手术,术后分成典必殊和氟美童两个组各90例(180只眼),每组又分为:A组低度近视组(0^-3.0D);B组中度近视组(-3.25^-6.0D);C组高度近视组(≥-6.25D)。观察术后1周、2周、1月及3个月眼压的变化。结果:典必殊组眼压明显大于氟美童组,典必殊组术后1周高眼压比率分别为26.7%、25%、20%,术后2周比率明显降低,术后1月比率稍有增高,术后3月眼压几乎恢复正常,氟美童组术后1周高眼压比率分别为10%、5%、6.7%,其余月份为0。结论:典必殊与氟美童均能很好的控制LASIK术后炎症反应,氟美童较典必殊更安全,术后早期应监测眼压。展开更多
文摘AIM： To compare the combination of fluorometholone0.1% and levofloxacin 0.5% to tobramycin/dexamethasone eye drops in controlling inflammation and preventing infection after phacoemulsification with an intraocular lens implantation.METHODS： Sixty eyes from 60 patients undergoing cataract phacoemulsification were randomized into two groups; half of the patients were treated with fluorometholone（6 times/d） combined with levofloxacin（4 times/d）, while the other half were treated with tobramycin/dexamethasone（4 times/d） eye drops for one week. Preoperative and postoperative intraocular pressure, aqueous flare, corneal thickness, and signs and symptoms were recorded before the operation and1 wk following treatments. RESULTS： There were no statistically significant differences between the two groups in corneal thickness（P ≥0.629）, aqueous flare（P ≥0.398）, and signs and symptoms scores（P ≥0.350） at each time point. Ocular hypertension was only observed in two eyes in the tobramycin/dexamethasone group. CONCLUSION： Fluorometholone combined with levofloxacin treatment shows comparable efficacy but without the tendency to increase intraocular pressure;thus, it might be a better regimen for postoperative use.
文摘目的:探讨准分子激光角膜原位磨镶术(Laser in situ keratomileusis,LASIK)术后分别使用典必殊及氟美童滴眼液,术后1周、2周、1月、3月眼压的变化。方法:180例(360只眼)近视眼患者,进行LASIK手术,术后分成典必殊和氟美童两个组各90例(180只眼),每组又分为:A组低度近视组(0^-3.0D);B组中度近视组(-3.25^-6.0D);C组高度近视组(≥-6.25D)。观察术后1周、2周、1月及3个月眼压的变化。结果:典必殊组眼压明显大于氟美童组,典必殊组术后1周高眼压比率分别为26.7%、25%、20%,术后2周比率明显降低,术后1月比率稍有增高,术后3月眼压几乎恢复正常,氟美童组术后1周高眼压比率分别为10%、5%、6.7%,其余月份为0。结论:典必殊与氟美童均能很好的控制LASIK术后炎症反应,氟美童较典必殊更安全,术后早期应监测眼压。
