Gallbladder cancer(GBC)is a rare and lethal malignancy;however,it represents the most common type of biliary tract cancer.Patients with GBC are often diagnosed at an advanced stage,thus,unfortunately,losing the opport...Gallbladder cancer(GBC)is a rare and lethal malignancy;however,it represents the most common type of biliary tract cancer.Patients with GBC are often diagnosed at an advanced stage,thus,unfortunately,losing the opportunity for curative surgical intervention.This situation leads to lower quality of life and higher mortality rates.In recent years,the rapid development of endoscopic equipment and techniques has provided new avenues and possibilities for the early and minimally invasive diagnosis and treatment of GBC.This editorial comments on the article by Pavlidis et al.Building upon their work,we explore the new needs and corresponding models for managing GBC from the endoscopic diagnosis and treatment perspective.展开更多
BACKGROUND Circular RNAs(circRNAs)are involved in the pathogenesis of many diseases through competing endogenous RNA(ceRNA)regulatory mechanisms.AIM To investigate a circRNA-related ceRNA regulatory network and a new ...BACKGROUND Circular RNAs(circRNAs)are involved in the pathogenesis of many diseases through competing endogenous RNA(ceRNA)regulatory mechanisms.AIM To investigate a circRNA-related ceRNA regulatory network and a new predictive model by circRNA to understand the diagnostic mechanism of circRNAs in ulcerative colitis(UC).METHODS We obtained gene expression profiles of circRNAs,miRNAs,and mRNAs in UC from the Gene Expression Omnibus dataset.The circRNA-miRNA-mRNA network was constructed based on circRNA-miRNA and miRNA-mRNA interactions.Functional enrichment analysis was performed to identify the biological mechanisms involved in circRNAs.We identified the most relevant differential circRNAs for diagnosing UC and constructed a new predictive nomogram,whose efficacy was tested with the C-index,receiver operating characteristic curve(ROC),and decision curve analysis(DCA).RESULTS A circRNA-miRNA-mRNA regulatory network was obtained,containing 12 circRNAs,three miRNAs,and 38 mRNAs.Two optimal prognostic-related differentially expressed circRNAs,hsa_circ_0085323 and hsa_circ_0036906,were included to construct a predictive nomogram.The model showed good discrimination,with a C-index of 1(>0.9,high accuracy).ROC and DCA suggested that the nomogram had a beneficial diagnostic ability.CONCLUSION This novel predictive nomogram incorporating hsa_circ_0085323 and hsa_circ_0036906 can be conveniently used to predict the risk of UC.The circRNa-miRNA-mRNA network in UC could be more clinically significant.展开更多
The synchronous virtual machine uses inverter power to imitate the performance of the conventional synchronous machine.It also has the same inertia,damping,frequency,voltage regulation,and other external performance a...The synchronous virtual machine uses inverter power to imitate the performance of the conventional synchronous machine.It also has the same inertia,damping,frequency,voltage regulation,and other external performance as the generator.It is the key technology to realize new energy grid connections’stable and reliable operation.This project studies a dynamic simulation model of an extensive new energy power system based on the virtual synchronous motor.A new energy storage method is proposed.The mathematical energy storage model is established by combining the fixed rotor model of a synchronous virtual machine with the charge-discharge power,state of charge,operation efficiency,dead zone,and inverter constraint.The rapid conversion of energy storage devices absorbs the excess instantaneous kinetic energy caused by interference.The branch transient of the critical cut set in the system can be confined to a limited area.Thus,the virtual synchronizer’s kinetic and potential energy can be efficiently converted into an instantaneous state.The simulation of power system analysis software package(PSASP)verifies the correctness of the theory and algorithm in this paper.This paper provides a theoretical basis for improving the transient stability of new energy-connected power grids.展开更多
Objective:To explore the impact of the construction of a clinical midwifery teaching faculty and the development of an evaluation system under the new nursing model on the current teaching quality.Methods:From July 20...Objective:To explore the impact of the construction of a clinical midwifery teaching faculty and the development of an evaluation system under the new nursing model on the current teaching quality.Methods:From July 2022 to March 2023,10 clinical teaching teachers and 20 midwifery interns from Beijing Anzhen Hospital affiliated with Capital Medical University were selected as the subjects of this study.The clinical teaching teachers and midwifery interns were divided into an observation group and a control group,with each group including 5 clinical teaching teachers and 10 midwifery interns.The observation group received daily management and evaluation under the new nursing model,while the control group received management and evaluation under the traditional nursing model.The teaching quality evaluation of clinical midwifery teaching teachers by midwifery interns,the exit exam scores of midwifery interns,and the scores of clinical teaching teachers’internship lectures and teaching rounds were compared between the two groups.Results:In the observation group,the scores for teaching attitude,teaching skills,and teaching management in the teaching quality evaluation of clinical midwifery teaching teachers were higher than those in the control group.The professional theory scores(91.28±3.64)and overall nursing comprehensive scores(92.56±4.38)of midwifery interns in the observation group were higher than those of midwifery interns in the control group(81.58±2.27 and 80.29±3.33,respectively).The scores for internship lectures(89.32±4.15)and teaching rounds(90.64±5.52)in the observation group were also significantly higher than those in the control group(80.46±3.28 and 81.24±4.38,respectively),and the differences were statistically significant(P<0.05).Conclusion:The management of the clinical midwifery teaching faculty under the new nursing model effectively improved the quality of clinical teaching.It significantly enhanced the teaching effectiveness of clinical teaching teachers and the proficiency of midwifery interns in clinical operations,making it worthy of promotion and use.展开更多
New energy vehicles represent the inevitable trend of future development.Compared to traditional fuel vehicles,they are more energy-saving and environmentally friendly,effectively reducing air pollution and mitigating...New energy vehicles represent the inevitable trend of future development.Compared to traditional fuel vehicles,they are more energy-saving and environmentally friendly,effectively reducing air pollution and mitigating excessive exploitation of oil resources,a stance strongly supported by governments.However,new energy vehicles possess certain drawbacks in terms of price and usability compared to traditional counterparts.Therefore,external support is imperative for their development.This paper delineates four main sections:the background of new energy vehicle promotion and application,a comparative analysis of domestic and foreign promotion models,specific promotion suggestions,and future development prospects.By leveraging insights from economic analysis,the optimal promotion model for new energy vehicles is elucidated.展开更多
The described structural model tries to answer some open questions such as: Why do quarks not exist in the open state? Where are the antiparticles from the Big Bang?
New energy vehicles have better clean and environmental protection characteristics than traditional fuel vehicles.The new energy engine cooling technology is critical in the design of new energy vehicles.This paper us...New energy vehicles have better clean and environmental protection characteristics than traditional fuel vehicles.The new energy engine cooling technology is critical in the design of new energy vehicles.This paper used oneand three-way joint simulation methods to simulate the refrigeration system of new energy vehicles.Firstly,a k-εturbulent flow model for the cooling pump flow field is established based on the principle of computational fluid dynamics.Then,the CFD commercial fluid analysis software FLUENT is used to simulate the flow field of the cooling pump under different inlet flow conditions.This paper proposes an optimization scheme for new energy vehicle engines’“boiling”phenomenon under high temperatures and long-time climbing conditions.The simulation results show that changing the radiator’s structure and adjusting the thermostat’s parameters can solve the problem of a“boiling pot.”The optimized new energy vehicle engine can maintain a better operating temperature range.The algorithm model can reference each cryogenic system component hardware selection and control strategy in the new energy vehicle’s engine.展开更多
This paper focuses on the problems,opportunities,and challenges faced by software engineering education in the new era.We have studied the core ideas of the new model and reform,the specific measures implemented,and t...This paper focuses on the problems,opportunities,and challenges faced by software engineering education in the new era.We have studied the core ideas of the new model and reform,the specific measures implemented,and the challenges and solutions faced.The new model and reform must focus on cultivating practical abilities,introducing interdisciplinary knowledge,and strengthening innovation awareness and entrepreneurial spirit.The process of reform and innovation is carried out from the aspects of teaching methods,teaching means,and course performance evaluation in the teaching practice of software engineering courses.We adopt a method of“question guiding,simple and easy to understand,flexible and diverse,and emphasizing practical results”,optimizing the curriculum design,providing diverse learning opportunities,and establishing a platform for the industry-university-research cooperation.Our teaching philosophy is to adhere to the viewpoint of innovative teaching ideas,optimizing teaching methods and teaching means,and comprehensively improving the teaching quality and level of software engineering education.展开更多
Study on crack propagation process of brittle rock is of most significance for cracking-arrest design and cracking-network optimization in rock engineering.Phase-field model(PFM)has advantages of simplicity and high c...Study on crack propagation process of brittle rock is of most significance for cracking-arrest design and cracking-network optimization in rock engineering.Phase-field model(PFM)has advantages of simplicity and high convergence over the common numerical methods(e.g.finite element method,discrete element method,and particle manifold method)in dealing with three-dimensional and multicrack problems.However,current PFMs are mainly used to simulate mode-I(tensile)crack propagation but difficult to effectively simulate mode-II(shear)crack propagation.In this paper,a new mixed-mode PFM is established to simulate both mode-I and mode-II crack propagation of brittle rock by distinguishing the volumetric elastic strain energy and deviatoric elastic strain energy in the total elastic strain energy and considering the effect of compressive stress on mode-II crack propagation.Numerical solution method of the new mixed-mode PFM is proposed based on the staggered solution method with self-programmed subroutines UMAT and HETVAL of ABAQUS software.Three examples calculated using different PFMs as well as test results are presented for comparison.The results show that compared with the conventional PFM(which only simulates the tensile wing crack but not mode-II crack propagation)and the modified mixed-mode PFM(which has difficulty in simulating the shear anti-wing crack),the new mixed-mode PFM can successfully simulate the whole trajectories of mixed-mode crack propagation(including the tensile wing crack,shear secondary crack,and shear anti-wing crack)and mode-II crack propagation,which are close to the test results.It can be further extended to simulate multicrack propagation of anisotropic rock under multi-field coupling loads.展开更多
Clastic rock reservoir is the main reservoir type in the oil and gas field.Archie formula or various conductive models developed on the basis of Archie’s formula are usually used to interpret this kind of reservoir,a...Clastic rock reservoir is the main reservoir type in the oil and gas field.Archie formula or various conductive models developed on the basis of Archie’s formula are usually used to interpret this kind of reservoir,and the three-water model is widely used as well.However,there are many parameters in the threewater model,and some of them are difficult to determine.Most of the determination methods are based on the statistics of large amount of experimental data.In this study,the authors determine the value of the parameters of the new three-water model based on the nuclear magnetic data and the genetic optimization algorithm.The relative error between the resistivity calculated based on these parameters and the resistivity measured experimentally at 100%water content is 0.9024.The method studied in this paper can be easily applied without much experimental data.It can provide reference for other regions to determine the parameters of the new three-water model.展开更多
Concrete slabs are widely used in modern railways to increase the inherent resilient quality of the tracks,provide safe and smooth rides,and reduce the maintenance frequency.In this paper,the elastic performance of a ...Concrete slabs are widely used in modern railways to increase the inherent resilient quality of the tracks,provide safe and smooth rides,and reduce the maintenance frequency.In this paper,the elastic performance of a novel slab trackform for high-speed railways is investigated using three-dimensional finite element modelling in Abaqus.It is then compared to the performance of a ballasted track.First,slab and ballasted track models are developed to replicate the full-scale testing of track sections.Once the models are calibrated with the experimental results,the novel slab model is developed and compared against the calibrated slab track results.The slab and ballasted track models are then extended to create linear dynamic models,considering the track geodynamics,and simulating train passages at various speeds,for which the Ledsgard documented case was used to validate the models.Trains travelling at low and high speeds are analysed to investigate the track deflections and the wave propagation in the soil,considering the issues associated with critical speeds.Various train loading methods are discussed,and the most practical approach is retained and described.Moreover,correlations are made between the geotechnical parameters of modern high-speed rail and conventional standards.It is found that considering the same ground condition,the slab track deflections are considerably smaller than those of the ballasted track at high speeds,while they show similar behaviour at low speeds.展开更多
Under the background of counter economic globalization,the Group of Twenty(G20)has become the primary platform for the east and west powers to seek consultation and dialogue.And the coordination mechanism of the new g...Under the background of counter economic globalization,the Group of Twenty(G20)has become the primary platform for the east and west powers to seek consultation and dialogue.And the coordination mechanism of the new global powers has come into being slowly.As a multilateral regional bank,the BRICsBank takes the interests of developing countries as the leading factor.Based on international economic cooperation ground,it will broaden the South-South cooperation to create more convenient conditions for foreign direct investment,as well as bilateral and multilateral financial cooperation.From new power coordination perspective,with global economy governance structure transformation as the starting point,this research accurately defines the concept of coordination mechanism,systematically analyzes the evolution of global economic governance structure,intensively interprets the current characteristics of big power coordination mode in global economic governance structure,and objective assesses trends of global political and economic pattern.It is of important policy reference implications for the BRICS member countries to effectively promote the BRICs Bank institutionalization and global governance of new power coordination nature.展开更多
THE ninth BRICS Summit will soon take place in September in Xiamen.The concept of"BRIC"was formed 10 years ago.In reviewing the past and looking to the future,it is expected that BRICS will continue to grow ...THE ninth BRICS Summit will soon take place in September in Xiamen.The concept of"BRIC"was formed 10 years ago.In reviewing the past and looking to the future,it is expected that BRICS will continue to grow and strengthen in the coming decade with more pragmatic cooperation.Essential展开更多
Recently,e-commerce develops rapidly,advancing express delivery services,but the whole logistics are incomplete,especially for the issue of "the last one-kilometer ".For example,the research reviewed status quo and ...Recently,e-commerce develops rapidly,advancing express delivery services,but the whole logistics are incomplete,especially for the issue of "the last one-kilometer ".For example,the research reviewed status quo and problems of Tianjin Agricultural University and made improvements on campus delivery services to explore the status quo and resolving ways,exploit the hint business opportunity in campus express model,improve efficiency and service attitude and get doublewin of both parties involved.展开更多
In this study, a new lumped-mass-stick model (LMSM) is developed based on the modal characteristics of a structure such as eigenvalues and eigenvectors. The simplified model, named the "frequency adaptive lumped-ma...In this study, a new lumped-mass-stick model (LMSM) is developed based on the modal characteristics of a structure such as eigenvalues and eigenvectors. The simplified model, named the "frequency adaptive lumped-massstick model," hasonly a small number of stick elements and nodes to provide the same natural frequencies of the structure and is applied to a nuclear containment building. To investigate the numerical performance of the LMSM, a time history analysis is carried out on both the LMSM and the finite element model (FEM) for a nuclear containment building. A comparison of the results shows that the dynamic responses of the LMSM in terms of displacement and acceleration are almost identical to those of the FEM. In addition, the results in terms of floor response spectra at certain elevations are also in good agreement.展开更多
Studies on the selective retinal degeneration induced by sodium iodate (NaIO3) date back to 1941; Sorsby (1941) described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3...Studies on the selective retinal degeneration induced by sodium iodate (NaIO3) date back to 1941; Sorsby (1941) described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3-induced retinal degeneration has been described in different mammalian species including sheep, rabbit, rat and mouse with varying doses and routes of administration. At the present time,展开更多
Based on a first order nonlinear ordinary differential equation with at most a sixth-degree nonlinear term which is extended from a type of elliptic equation, and by converting it into a new expansion form, this paper...Based on a first order nonlinear ordinary differential equation with at most a sixth-degree nonlinear term which is extended from a type of elliptic equation, and by converting it into a new expansion form, this paper proposes a new algebraic method to construct exact solutions for nonlinear evolution equations. Being concise and straightforward, the method is applied to modified Benjamin-Bona-Mahony (mBBM) model, and some new exact solutions to the system are obtained. The algorithm is of important significance in exploring exact solutions for other nonlinear evolution equations.展开更多
On the basis of a detailed discussion of the development of total ionizing dose (TID) effect model, a new commercial-model-independent TID modeling approach for partially depleted silicon-on-insulator metal-oxide- s...On the basis of a detailed discussion of the development of total ionizing dose (TID) effect model, a new commercial-model-independent TID modeling approach for partially depleted silicon-on-insulator metal-oxide- semiconductor field effect transistors is developed. An exponential approximation is proposed to simplify the trap charge calculation. Irradiation experiments with 60Co gamma rays for IO and core devices are performed to validate the simulation results. An excellent agreement of measurement with the simulation results is observed.展开更多
基金the Education and Teaching Reform Project of the First Clinical College of Chongqing Medical University,No.CMER202305the Program for Youth Innovation in Future Medicine,Chongqing Medical University,No.W0138.
文摘Gallbladder cancer(GBC)is a rare and lethal malignancy;however,it represents the most common type of biliary tract cancer.Patients with GBC are often diagnosed at an advanced stage,thus,unfortunately,losing the opportunity for curative surgical intervention.This situation leads to lower quality of life and higher mortality rates.In recent years,the rapid development of endoscopic equipment and techniques has provided new avenues and possibilities for the early and minimally invasive diagnosis and treatment of GBC.This editorial comments on the article by Pavlidis et al.Building upon their work,we explore the new needs and corresponding models for managing GBC from the endoscopic diagnosis and treatment perspective.
基金Supported by the National Natural Science Foundation of China,No.81774093,No.81904009,No.81974546 and No.82174182Key R&D Project of Hubei Province,No.2020BCB001.
文摘BACKGROUND Circular RNAs(circRNAs)are involved in the pathogenesis of many diseases through competing endogenous RNA(ceRNA)regulatory mechanisms.AIM To investigate a circRNA-related ceRNA regulatory network and a new predictive model by circRNA to understand the diagnostic mechanism of circRNAs in ulcerative colitis(UC).METHODS We obtained gene expression profiles of circRNAs,miRNAs,and mRNAs in UC from the Gene Expression Omnibus dataset.The circRNA-miRNA-mRNA network was constructed based on circRNA-miRNA and miRNA-mRNA interactions.Functional enrichment analysis was performed to identify the biological mechanisms involved in circRNAs.We identified the most relevant differential circRNAs for diagnosing UC and constructed a new predictive nomogram,whose efficacy was tested with the C-index,receiver operating characteristic curve(ROC),and decision curve analysis(DCA).RESULTS A circRNA-miRNA-mRNA regulatory network was obtained,containing 12 circRNAs,three miRNAs,and 38 mRNAs.Two optimal prognostic-related differentially expressed circRNAs,hsa_circ_0085323 and hsa_circ_0036906,were included to construct a predictive nomogram.The model showed good discrimination,with a C-index of 1(>0.9,high accuracy).ROC and DCA suggested that the nomogram had a beneficial diagnostic ability.CONCLUSION This novel predictive nomogram incorporating hsa_circ_0085323 and hsa_circ_0036906 can be conveniently used to predict the risk of UC.The circRNa-miRNA-mRNA network in UC could be more clinically significant.
文摘The synchronous virtual machine uses inverter power to imitate the performance of the conventional synchronous machine.It also has the same inertia,damping,frequency,voltage regulation,and other external performance as the generator.It is the key technology to realize new energy grid connections’stable and reliable operation.This project studies a dynamic simulation model of an extensive new energy power system based on the virtual synchronous motor.A new energy storage method is proposed.The mathematical energy storage model is established by combining the fixed rotor model of a synchronous virtual machine with the charge-discharge power,state of charge,operation efficiency,dead zone,and inverter constraint.The rapid conversion of energy storage devices absorbs the excess instantaneous kinetic energy caused by interference.The branch transient of the critical cut set in the system can be confined to a limited area.Thus,the virtual synchronizer’s kinetic and potential energy can be efficiently converted into an instantaneous state.The simulation of power system analysis software package(PSASP)verifies the correctness of the theory and algorithm in this paper.This paper provides a theoretical basis for improving the transient stability of new energy-connected power grids.
基金Capital Medical University 2023 Education and Teaching Reform Research Project“Study on the Construction and Evaluation System of Clinical Midwifery Teaching Faculty under the New Nursing Model”(Project No.2023JYZ028)。
文摘Objective:To explore the impact of the construction of a clinical midwifery teaching faculty and the development of an evaluation system under the new nursing model on the current teaching quality.Methods:From July 2022 to March 2023,10 clinical teaching teachers and 20 midwifery interns from Beijing Anzhen Hospital affiliated with Capital Medical University were selected as the subjects of this study.The clinical teaching teachers and midwifery interns were divided into an observation group and a control group,with each group including 5 clinical teaching teachers and 10 midwifery interns.The observation group received daily management and evaluation under the new nursing model,while the control group received management and evaluation under the traditional nursing model.The teaching quality evaluation of clinical midwifery teaching teachers by midwifery interns,the exit exam scores of midwifery interns,and the scores of clinical teaching teachers’internship lectures and teaching rounds were compared between the two groups.Results:In the observation group,the scores for teaching attitude,teaching skills,and teaching management in the teaching quality evaluation of clinical midwifery teaching teachers were higher than those in the control group.The professional theory scores(91.28±3.64)and overall nursing comprehensive scores(92.56±4.38)of midwifery interns in the observation group were higher than those of midwifery interns in the control group(81.58±2.27 and 80.29±3.33,respectively).The scores for internship lectures(89.32±4.15)and teaching rounds(90.64±5.52)in the observation group were also significantly higher than those in the control group(80.46±3.28 and 81.24±4.38,respectively),and the differences were statistically significant(P<0.05).Conclusion:The management of the clinical midwifery teaching faculty under the new nursing model effectively improved the quality of clinical teaching.It significantly enhanced the teaching effectiveness of clinical teaching teachers and the proficiency of midwifery interns in clinical operations,making it worthy of promotion and use.
文摘New energy vehicles represent the inevitable trend of future development.Compared to traditional fuel vehicles,they are more energy-saving and environmentally friendly,effectively reducing air pollution and mitigating excessive exploitation of oil resources,a stance strongly supported by governments.However,new energy vehicles possess certain drawbacks in terms of price and usability compared to traditional counterparts.Therefore,external support is imperative for their development.This paper delineates four main sections:the background of new energy vehicle promotion and application,a comparative analysis of domestic and foreign promotion models,specific promotion suggestions,and future development prospects.By leveraging insights from economic analysis,the optimal promotion model for new energy vehicles is elucidated.
文摘The described structural model tries to answer some open questions such as: Why do quarks not exist in the open state? Where are the antiparticles from the Big Bang?
文摘New energy vehicles have better clean and environmental protection characteristics than traditional fuel vehicles.The new energy engine cooling technology is critical in the design of new energy vehicles.This paper used oneand three-way joint simulation methods to simulate the refrigeration system of new energy vehicles.Firstly,a k-εturbulent flow model for the cooling pump flow field is established based on the principle of computational fluid dynamics.Then,the CFD commercial fluid analysis software FLUENT is used to simulate the flow field of the cooling pump under different inlet flow conditions.This paper proposes an optimization scheme for new energy vehicle engines’“boiling”phenomenon under high temperatures and long-time climbing conditions.The simulation results show that changing the radiator’s structure and adjusting the thermostat’s parameters can solve the problem of a“boiling pot.”The optimized new energy vehicle engine can maintain a better operating temperature range.The algorithm model can reference each cryogenic system component hardware selection and control strategy in the new energy vehicle’s engine.
基金supported in part by the postgraduate demonstration course of Guangdong Province Department of Education Programmed Trading(No.2023SFKC_022)the Computer Architecture First Class Course Project,South China Normal University-Baidu Pineapple Talent Training Practice Basethe 2023 Project of Computer Education Research Association of Chinese Universities(No.CERACU2023R02)。
文摘This paper focuses on the problems,opportunities,and challenges faced by software engineering education in the new era.We have studied the core ideas of the new model and reform,the specific measures implemented,and the challenges and solutions faced.The new model and reform must focus on cultivating practical abilities,introducing interdisciplinary knowledge,and strengthening innovation awareness and entrepreneurial spirit.The process of reform and innovation is carried out from the aspects of teaching methods,teaching means,and course performance evaluation in the teaching practice of software engineering courses.We adopt a method of“question guiding,simple and easy to understand,flexible and diverse,and emphasizing practical results”,optimizing the curriculum design,providing diverse learning opportunities,and establishing a platform for the industry-university-research cooperation.Our teaching philosophy is to adhere to the viewpoint of innovative teaching ideas,optimizing teaching methods and teaching means,and comprehensively improving the teaching quality and level of software engineering education.
基金supports by National Natural Science Foundation of China(Grant Nos.51874351 and 52078495)Excellent Postdoctoral Innovative Talents Project of Hunan Province,China(Grant No.2020RC2001).
文摘Study on crack propagation process of brittle rock is of most significance for cracking-arrest design and cracking-network optimization in rock engineering.Phase-field model(PFM)has advantages of simplicity and high convergence over the common numerical methods(e.g.finite element method,discrete element method,and particle manifold method)in dealing with three-dimensional and multicrack problems.However,current PFMs are mainly used to simulate mode-I(tensile)crack propagation but difficult to effectively simulate mode-II(shear)crack propagation.In this paper,a new mixed-mode PFM is established to simulate both mode-I and mode-II crack propagation of brittle rock by distinguishing the volumetric elastic strain energy and deviatoric elastic strain energy in the total elastic strain energy and considering the effect of compressive stress on mode-II crack propagation.Numerical solution method of the new mixed-mode PFM is proposed based on the staggered solution method with self-programmed subroutines UMAT and HETVAL of ABAQUS software.Three examples calculated using different PFMs as well as test results are presented for comparison.The results show that compared with the conventional PFM(which only simulates the tensile wing crack but not mode-II crack propagation)and the modified mixed-mode PFM(which has difficulty in simulating the shear anti-wing crack),the new mixed-mode PFM can successfully simulate the whole trajectories of mixed-mode crack propagation(including the tensile wing crack,shear secondary crack,and shear anti-wing crack)and mode-II crack propagation,which are close to the test results.It can be further extended to simulate multicrack propagation of anisotropic rock under multi-field coupling loads.
文摘Clastic rock reservoir is the main reservoir type in the oil and gas field.Archie formula or various conductive models developed on the basis of Archie’s formula are usually used to interpret this kind of reservoir,and the three-water model is widely used as well.However,there are many parameters in the threewater model,and some of them are difficult to determine.Most of the determination methods are based on the statistics of large amount of experimental data.In this study,the authors determine the value of the parameters of the new three-water model based on the nuclear magnetic data and the genetic optimization algorithm.The relative error between the resistivity calculated based on these parameters and the resistivity measured experimentally at 100%water content is 0.9024.The method studied in this paper can be easily applied without much experimental data.It can provide reference for other regions to determine the parameters of the new three-water model.
基金Engineering and Physical Sciences Research Council (EPSRC) is also acknowledged for funding this work under Grant Number EP/N009207/1.
文摘Concrete slabs are widely used in modern railways to increase the inherent resilient quality of the tracks,provide safe and smooth rides,and reduce the maintenance frequency.In this paper,the elastic performance of a novel slab trackform for high-speed railways is investigated using three-dimensional finite element modelling in Abaqus.It is then compared to the performance of a ballasted track.First,slab and ballasted track models are developed to replicate the full-scale testing of track sections.Once the models are calibrated with the experimental results,the novel slab model is developed and compared against the calibrated slab track results.The slab and ballasted track models are then extended to create linear dynamic models,considering the track geodynamics,and simulating train passages at various speeds,for which the Ledsgard documented case was used to validate the models.Trains travelling at low and high speeds are analysed to investigate the track deflections and the wave propagation in the soil,considering the issues associated with critical speeds.Various train loading methods are discussed,and the most practical approach is retained and described.Moreover,correlations are made between the geotechnical parameters of modern high-speed rail and conventional standards.It is found that considering the same ground condition,the slab track deflections are considerably smaller than those of the ballasted track at high speeds,while they show similar behaviour at low speeds.
文摘Under the background of counter economic globalization,the Group of Twenty(G20)has become the primary platform for the east and west powers to seek consultation and dialogue.And the coordination mechanism of the new global powers has come into being slowly.As a multilateral regional bank,the BRICsBank takes the interests of developing countries as the leading factor.Based on international economic cooperation ground,it will broaden the South-South cooperation to create more convenient conditions for foreign direct investment,as well as bilateral and multilateral financial cooperation.From new power coordination perspective,with global economy governance structure transformation as the starting point,this research accurately defines the concept of coordination mechanism,systematically analyzes the evolution of global economic governance structure,intensively interprets the current characteristics of big power coordination mode in global economic governance structure,and objective assesses trends of global political and economic pattern.It is of important policy reference implications for the BRICS member countries to effectively promote the BRICs Bank institutionalization and global governance of new power coordination nature.
文摘THE ninth BRICS Summit will soon take place in September in Xiamen.The concept of"BRIC"was formed 10 years ago.In reviewing the past and looking to the future,it is expected that BRICS will continue to grow and strengthen in the coming decade with more pragmatic cooperation.Essential
文摘Recently,e-commerce develops rapidly,advancing express delivery services,but the whole logistics are incomplete,especially for the issue of "the last one-kilometer ".For example,the research reviewed status quo and problems of Tianjin Agricultural University and made improvements on campus delivery services to explore the status quo and resolving ways,exploit the hint business opportunity in campus express model,improve efficiency and service attitude and get doublewin of both parties involved.
基金Energy Efficiency & Resources of the Korea Institute of Energy Technology Evaluation and Planning (KETEP), Ministry of Knowledge Economy, Republic of Korea under Grant No. 2010T100101066
文摘In this study, a new lumped-mass-stick model (LMSM) is developed based on the modal characteristics of a structure such as eigenvalues and eigenvectors. The simplified model, named the "frequency adaptive lumped-massstick model," hasonly a small number of stick elements and nodes to provide the same natural frequencies of the structure and is applied to a nuclear containment building. To investigate the numerical performance of the LMSM, a time history analysis is carried out on both the LMSM and the finite element model (FEM) for a nuclear containment building. A comparison of the results shows that the dynamic responses of the LMSM in terms of displacement and acceleration are almost identical to those of the FEM. In addition, the results in terms of floor response spectra at certain elevations are also in good agreement.
基金supported in part by grants EY01545 and by core grant EY03040the Arnold and Mabel Beckman Foundationan unrestricted grant to the Department of Ophthalmology from Research to Prevent Blindness Inc.,New York,NY
文摘Studies on the selective retinal degeneration induced by sodium iodate (NaIO3) date back to 1941; Sorsby (1941) described the effect of intravenously injected NaIO3 solution on the rabbit retina. Since then, NaIO3-induced retinal degeneration has been described in different mammalian species including sheep, rabbit, rat and mouse with varying doses and routes of administration. At the present time,
基金Project supported by the Science and Technology Foundation of Guizhou Province,China (Grant No 20072009)
文摘Based on a first order nonlinear ordinary differential equation with at most a sixth-degree nonlinear term which is extended from a type of elliptic equation, and by converting it into a new expansion form, this paper proposes a new algebraic method to construct exact solutions for nonlinear evolution equations. Being concise and straightforward, the method is applied to modified Benjamin-Bona-Mahony (mBBM) model, and some new exact solutions to the system are obtained. The algorithm is of important significance in exploring exact solutions for other nonlinear evolution equations.
基金Supported by the National Natural Science Foundation of China under Grant Nos 61404151 and 61574153
文摘On the basis of a detailed discussion of the development of total ionizing dose (TID) effect model, a new commercial-model-independent TID modeling approach for partially depleted silicon-on-insulator metal-oxide- semiconductor field effect transistors is developed. An exponential approximation is proposed to simplify the trap charge calculation. Irradiation experiments with 60Co gamma rays for IO and core devices are performed to validate the simulation results. An excellent agreement of measurement with the simulation results is observed.