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基于改进Event模型的通用航空器碰撞风险分析
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作者 黄晋 焦瑶瑶 +1 位作者 李云飞 刘厚荣 《火力与指挥控制》 CSCD 北大核心 2024年第10期191-196,共6页
随着通用航空的发展,空中交通流量将持续扩大,航空器碰撞风险增加。对Event模型进行改进,将拼接四棱锥碰撞盒代替原长方体碰撞盒,曲面间隔层代替平面间隔层,建立通用航空器碰撞风险模型。最后将塞斯纳172及运5B通用航空器作为实例对所... 随着通用航空的发展,空中交通流量将持续扩大,航空器碰撞风险增加。对Event模型进行改进,将拼接四棱锥碰撞盒代替原长方体碰撞盒,曲面间隔层代替平面间隔层,建立通用航空器碰撞风险模型。最后将塞斯纳172及运5B通用航空器作为实例对所建模型进行验证,结果表明,在两组均采用广义帕累托分布的条件下,改进后Event模型碰撞风险值分别为改进前的31.65%、14.98%,碰撞风险值较改进前大大减少,结果精度更高,能更好地评估交叉航路碰撞风险。 展开更多
关键词 event模型 碰撞风险 曲面间隔层 广义帕累托分布
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Plasma big endothelin-1 is an effective predictor for ventricular arrythmias and end-stage events in primary prevention implantable cardioverter-defibrillator indication patients 被引量:1
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作者 Xiao-Yao LI Shuang ZHAO +6 位作者 Xiao-Han FAN Ke-Ping CHEN Wei HUA Zhi-Min LIU Xiao-Di XUE Bin ZHOU Shu ZHANG 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2020年第7期427-433,共7页
Objective To investigate whether plasma big endothelin-1(ET-1) predicts ventricular arrythmias(VAs) and end-stage events in primary prevention implantable cardioverter-defibrillator(ICD) indication patigents. Methods ... Objective To investigate whether plasma big endothelin-1(ET-1) predicts ventricular arrythmias(VAs) and end-stage events in primary prevention implantable cardioverter-defibrillator(ICD) indication patigents. Methods In total, 207 patients fulfilling the inclusion criteria from Fuwai Hospital between January 2013 and December 2015 were retrospectively analyzed. The cohort was divided into three groups according to baseline plasma big ET-1 tertiles: tertile 1(< 0.38 pmol/L, n = 68), tertile 2(0.38–0.7 pmol/L, n = 69), and tertile 3(> 0.7 pmol/L, n = 70). The primary endpoints were VAs. The secondary endpoints were end-stage events comprising all-cause mortality and heart transplantation. Results During a mean follow-up period of 25.6 ± 13.9 months, 38(18.4%) VAs and 78(37.7%) end-stage events occurred. Big ET-1 was positively correlated with NYHA class(r = 0.165, P = 0.018), serum creatinine concentration(Scr;r = 0.147, P = 0.034), high-sensitivity C-reactive protein(hs-CRP;r = 0.217, P = 0.002), Lg NT-pro BNP(r = 0.463, P < 0.001), left ventricular end diastolic diameter(LVEDD;r = 0.234, P = 0.039) and negatively correlated with left ventricular ejection fraction(LVEF;r =-0.181, P = 0.032). Kaplan-Meier analysis showed that elevated big ET-1 was associated with increased risk of VAs and end-stage events(P < 0.05). In multivariate Cox regression models, big ET-1 was an independent risk factor for VAs(hazard ratio(HR) = 3.477, 95% confidence interval(CI): 1.352–8.940, P = 0.010, tertile 2 vs. tertile 1;HR = 4.112, 95% CI: 1.604–10.540, P = 0.003, tertile 3 vs. tertile 1) and end-stage events(HR = 2.804, 95% CI: 1.354–5.806, P = 0.005, tertile 2 vs. tertile 1;HR = 4.652, 95% CI: 2.288–9.459, P < 0.001, tertile 3 vs. tertile 1). Conclusions In primary prevention ICD indication patients, plasma big ET-1 levels can predict VAs and end-stage events and may facilitate ICD-implantation risk stratification. 展开更多
关键词 big endothelin-1 End-stage events Implantable cardioverter-defibrillator implantation Primary prevention Ventricular arrythmias
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Impact of Big Events on Urban Renewal Based on Urban Catalyst Theory: A Case Study of 2016 Rio Summer Olympics and 2010 Shanghai World Expo
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作者 BAI Mei ZHOU Yang TAO Danyang 《Journal of Landscape Research》 2022年第6期57-60,共4页
With the acceleration of the process of economic globalization and information synchronization, every major event is accompanied by the simultaneous renewal of the city. In the era of urban development, the launch of ... With the acceleration of the process of economic globalization and information synchronization, every major event is accompanied by the simultaneous renewal of the city. In the era of urban development, the launch of major events is also for the renewal and development of the city. 2016 Rio Summer Olympics and 2010 Shanghai World Expo are taken as the research objects. Through the analysis of urban renewal from the perspective of the role of big event catalyst, it is verified that the big event catalyst has a positive impact on urban renewal, transportation, industrial transformation and other aspects. Moreover, it tries to combine the theory of urban catalyst to analyze its inspiration for the Beijing Winter Olympic Games, hoping to play a catalytic role in accelerating the urban renewal and transformation of Beijing and the reorganization of urban structure. 展开更多
关键词 big event CATALYST Urban renewal
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Projecting Spring Consecutive Rainfall Events in the Three Gorges Reservoir Based on Triple-Nested Dynamical Downscaling 被引量:2
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作者 Yanxin ZHENG Shuanglin LI +2 位作者 Noel KEENLYSIDE Shengping HE Lingling SUO 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第8期1539-1558,共20页
Spring consecutive rainfall events(CREs) are key triggers of geological hazards in the Three Gorges Reservoir area(TGR), China. However, previous projections of CREs based on the direct outputs of global climate model... Spring consecutive rainfall events(CREs) are key triggers of geological hazards in the Three Gorges Reservoir area(TGR), China. However, previous projections of CREs based on the direct outputs of global climate models(GCMs) are subject to considerable uncertainties, largely caused by their coarse resolution. This study applies a triple-nested WRF(Weather Research and Forecasting) model dynamical downscaling, driven by a GCM, MIROC6(Model for Interdisciplinary Research on Climate, version 6), to improve the historical simulation and reduce the uncertainties in the future projection of CREs in the TGR. Results indicate that WRF has better performances in reproducing the observed rainfall in terms of the daily probability distribution, monthly evolution and duration of rainfall events, demonstrating the ability of WRF in simulating CREs. Thus, the triple-nested WRF is applied to project the future changes of CREs under the middle-of-the-road and fossil-fueled development scenarios. It is indicated that light and moderate rainfall and the duration of continuous rainfall spells will decrease in the TGR, leading to a decrease in the frequency of CREs. Meanwhile, the duration, rainfall amount, and intensity of CREs is projected to regional increase in the central-west TGR. These results are inconsistent with the raw projection of MIROC6. Observational diagnosis implies that CREs are mainly contributed by the vertical moisture advection. Such a synoptic contribution is captured well by WRF, which is not the case in MIROC6,indicating larger uncertainties in the CREs projected by MIROC6. 展开更多
关键词 triple-nested downscaling Three Gorges Reservoir area consecutive rainfall events geological hazards PROJECTION
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Reliability evaluation of IGBT power module on electric vehicle using big data 被引量:1
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作者 Li Liu Lei Tang +5 位作者 Huaping Jiang Fanyi Wei Zonghua Li Changhong Du Qianlei Peng Guocheng Lu 《Journal of Semiconductors》 EI CAS CSCD 2024年第5期50-60,共11页
There are challenges to the reliability evaluation for insulated gate bipolar transistors(IGBT)on electric vehicles,such as junction temperature measurement,computational and storage resources.In this paper,a junction... There are challenges to the reliability evaluation for insulated gate bipolar transistors(IGBT)on electric vehicles,such as junction temperature measurement,computational and storage resources.In this paper,a junction temperature estimation approach based on neural network without additional cost is proposed and the lifetime calculation for IGBT using electric vehicle big data is performed.The direct current(DC)voltage,operation current,switching frequency,negative thermal coefficient thermistor(NTC)temperature and IGBT lifetime are inputs.And the junction temperature(T_(j))is output.With the rain flow counting method,the classified irregular temperatures are brought into the life model for the failure cycles.The fatigue accumulation method is then used to calculate the IGBT lifetime.To solve the limited computational and storage resources of electric vehicle controllers,the operation of IGBT lifetime calculation is running on a big data platform.The lifetime is then transmitted wirelessly to electric vehicles as input for neural network.Thus the junction temperature of IGBT under long-term operating conditions can be accurately estimated.A test platform of the motor controller combined with the vehicle big data server is built for the IGBT accelerated aging test.Subsequently,the IGBT lifetime predictions are derived from the junction temperature estimation by the neural network method and the thermal network method.The experiment shows that the lifetime prediction based on a neural network with big data demonstrates a higher accuracy than that of the thermal network,which improves the reliability evaluation of system. 展开更多
关键词 IGBT junction temperature neural network electric vehicles big data
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Hadoop-based secure storage solution for big data in cloud computing environment 被引量:1
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作者 Shaopeng Guan Conghui Zhang +1 位作者 Yilin Wang Wenqing Liu 《Digital Communications and Networks》 SCIE CSCD 2024年第1期227-236,共10页
In order to address the problems of the single encryption algorithm,such as low encryption efficiency and unreliable metadata for static data storage of big data platforms in the cloud computing environment,we propose... In order to address the problems of the single encryption algorithm,such as low encryption efficiency and unreliable metadata for static data storage of big data platforms in the cloud computing environment,we propose a Hadoop based big data secure storage scheme.Firstly,in order to disperse the NameNode service from a single server to multiple servers,we combine HDFS federation and HDFS high-availability mechanisms,and use the Zookeeper distributed coordination mechanism to coordinate each node to achieve dual-channel storage.Then,we improve the ECC encryption algorithm for the encryption of ordinary data,and adopt a homomorphic encryption algorithm to encrypt data that needs to be calculated.To accelerate the encryption,we adopt the dualthread encryption mode.Finally,the HDFS control module is designed to combine the encryption algorithm with the storage model.Experimental results show that the proposed solution solves the problem of a single point of failure of metadata,performs well in terms of metadata reliability,and can realize the fault tolerance of the server.The improved encryption algorithm integrates the dual-channel storage mode,and the encryption storage efficiency improves by 27.6% on average. 展开更多
关键词 big data security Data encryption HADOOP Parallel encrypted storage Zookeeper
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Anthropogenic Influence on Decadal Changes in Concurrent Hot and Dry Events over China around the Mid-1990s 被引量:1
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作者 Qin SU Buwen DONG +1 位作者 Fangxing TIAN Nicholas P.KLINGAMAN 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第2期233-246,共14页
The frequency and duration of observed concurrent hot and dry events(HDEs) over China during the growing season(April–September) exhibit significant decadal changes across the mid-1990s. These changes are characteriz... The frequency and duration of observed concurrent hot and dry events(HDEs) over China during the growing season(April–September) exhibit significant decadal changes across the mid-1990s. These changes are characterized by increases in HDE frequency and duration over most of China, with relatively large increases over southeastern China(SEC), northern China(NC), and northeastern China(NEC). The frequency of HDEs averaged over China in the present day(PD,1994–2011) is double that in the early period(EP, 1964–81);the duration of HDEs increases by 60%. Climate experiments with the Met Office Unified Model(MetUM-GOML2) are used to estimate the contributions of anthropogenic forcing to HDE decadal changes over China. Anthropogenic forcing changes can explain 60%–70% of the observed decadal changes,suggesting an important anthropogenic influence on HDE changes over China across the mid-1990s. Single-forcing experiments indicate that the increase in greenhouse gas(GHG) concentrations dominates the simulated decadal changes,increasing the frequency and duration of HDEs throughout China. The change in anthropogenic aerosol(AA) emissions significantly decreases the frequency and duration of HDEs over SEC and NC, but the magnitude of the decrease is much smaller than the increase induced by GHGs. The changes in HDEs in response to anthropogenic forcing are mainly due to the response of climatological mean surface air temperatures. The contributions from changes in variability and changes in climatological mean soil moisture and evapotranspiration are relatively small. The physical processes associated with the response of HDEs to GHG and AA changes are also revealed. 展开更多
关键词 concurrent hot and dry events decadal variation greenhouse gases aerosol emissions
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Prediabetes: An overlooked risk factor for major adverse cardiac and cerebrovascular events in atrial fibrillation patients 被引量:2
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作者 Rupak Desai Nishanth Katukuri +9 位作者 Sumaja Reddy Goguri Azra Kothawala Naga Ruthvika Alle Meena Kumari Bellamkonda Debankur Dey Sharmila Ganesan Minakshi Biswas Kuheli Sarkar Pramoda Prattipati Shaylika Chauhan 《World Journal of Diabetes》 SCIE 2024年第1期24-33,共10页
BACKGROUND Prediabetes is a well-established risk factor for major adverse cardiac and cerebrovascular events(MACCE).However,the relationship between prediabetes and MACCE in atrial fibrillation(AF)patients has not be... BACKGROUND Prediabetes is a well-established risk factor for major adverse cardiac and cerebrovascular events(MACCE).However,the relationship between prediabetes and MACCE in atrial fibrillation(AF)patients has not been extensively studied.Therefore,this study aimed to establish a link between prediabetes and MACCE in AF patients.AIM To investigate a link between prediabetes and MACCE in AF patients.METHODS We used the National Inpatient Sample(2019)and relevant ICD-10 CM codes to identify hospitalizations with AF and categorized them into groups with and without prediabetes,excluding diabetics.The primary outcome was MACCE(all-cause inpatient mortality,cardiac arrest including ventricular fibrillation,and stroke)in AF-related hospitalizations.RESULTS Of the 2965875 AF-related hospitalizations for MACCE,47505(1.6%)were among patients with prediabetes.The prediabetes cohort was relatively younger(median 75 vs 78 years),and often consisted of males(56.3%vs 51.4%),blacks(9.8%vs 7.9%),Hispanics(7.3%vs 4.3%),and Asians(4.7%vs 1.6%)than the non-prediabetic cohort(P<0.001).The prediabetes group had significantly higher rates of hypertension,hyperlipidemia,smoking,obesity,drug abuse,prior myocardial infarction,peripheral vascular disease,and hyperthyroidism(all P<0.05).The prediabetes cohort was often discharged routinely(51.1%vs 41.1%),but more frequently required home health care(23.6%vs 21.0%)and had higher costs.After adjusting for baseline characteristics or comorbidities,the prediabetes cohort with AF admissions showed a higher rate and significantly higher odds of MACCE compared to the non-prediabetic cohort[18.6%vs 14.7%,odds ratio(OR)1.34,95%confidence interval 1.26-1.42,P<0.001].On subgroup analyses,males had a stronger association(aOR 1.43)compared to females(aOR 1.22),whereas on the race-wise comparison,Hispanics(aOR 1.43)and Asians(aOR 1.36)had a stronger association with MACCE with prediabetes vs whites(aOR 1.33)and blacks(aOR 1.21).CONCLUSION This population-based study found a significant association between prediabetes and MACCE in AF patients.Therefore,there is a need for further research to actively screen and manage prediabetes in AF to prevent MACCE. 展开更多
关键词 PREDIABETES Atrial fibrillation Cardiovascular disease risk Major adverse cardiovascular and cerebrovascular events Stroke MORTALITY
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Study of primordial deuterium abundance in Big Bang nucleosynthesis 被引量:1
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作者 Zhi-Lin Shen Jian-Jun He 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第3期208-215,共8页
Big Bang nucleosynthesis(BBN)theory predicts the primordial abundances of the light elements^(2) H(referred to as deuterium,or D for short),^(3)He,^(4)He,and^(7) Li produced in the early universe.Among these,deuterium... Big Bang nucleosynthesis(BBN)theory predicts the primordial abundances of the light elements^(2) H(referred to as deuterium,or D for short),^(3)He,^(4)He,and^(7) Li produced in the early universe.Among these,deuterium,the first nuclide produced by BBN,is a key primordial material for subsequent reactions.To date,the uncertainty in predicted deuterium abundance(D/H)remains larger than the observational precision.In this study,the Monte Carlo simulation code PRIMAT was used to investigate the sensitivity of 11 important BBN reactions to deuterium abundance.We found that the reaction rate uncertainties of the four reactions d(d,n)^(3)He,d(d,p)t,d(p,γ)^(3)He,and p(n,γ)d had the largest influence on the calculated D/H uncertainty.Currently,the calculated D/H uncertainty cannot reach observational precision even with the recent LUNA precise d(p,γ)^(3) He rate.From the nuclear physics aspect,there is still room to largely reduce the reaction-rate uncertainties;hence,further measurements of the important reactions involved in BBN are still necessary.A photodisintegration experiment will be conducted at the Shanghai Laser Electron Gamma Source Facility to precisely study the deuterium production reaction of p(n,γ)d. 展开更多
关键词 big Bang nucleosynthesis Abundance of deuterium Reaction cross section Reaction rate Monte Carlo method
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Increased retinal venule diameter as a prognostic indicator for recurrent cerebrovascular events:a prospective observational study 被引量:1
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作者 Ying Zhao Dawei Dong +5 位作者 Ding Yan Bing Yang Weirong Gui Man Ke Anding Xu Zefeng Tan 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第5期1156-1160,共5页
Microvasculature of the retina is considered an alternative marker of cerebral vascular risk in healthy populations.However,the ability of retinal vasculature changes,specifically focusing on retinal vessel diameter,t... Microvasculature of the retina is considered an alternative marker of cerebral vascular risk in healthy populations.However,the ability of retinal vasculature changes,specifically focusing on retinal vessel diameter,to predict the recurrence of cerebrovascular events in patients with ischemic stroke has not been determined comprehensively.While previous studies have shown a link between retinal vessel diameter and recurrent cerebrovascular events,they have not incorporated this information into a predictive model.Therefore,this study aimed to investigate the relationship between retinal vessel diameter and subsequent cerebrovascular events in patients with acute ischemic stroke.Additionally,we sought to establish a predictive model by combining retinal veessel diameter with traditional risk factors.We performed a prospective observational study of 141 patients with acute ischemic stroke who were admitted to the First Affiliated Hospital of Jinan University.All of these patients underwent digital retinal imaging within 72 hours of admission and were followed up for 3 years.We found that,after adjusting for related risk factors,patients with acute ischemic stroke with mean arteriolar diameter within 0.5-1.0 disc diameters of the disc margin(MAD_(0.5-1.0DD))of≥74.14μm and mean venular diameter within 0.5-1.0 disc diameters of the disc margin(MVD_(0.5-1.0DD))of≥83.91μm tended to experience recurrent cerebrovascular events.We established three multivariate Cox proportional hazard regression models:model 1 included traditional risk factors,model 2 added MAD_(0.5-1.0DD)to model 1,and model 3 added MVD0.5-1.0DD to model 1.Model 3 had the greatest potential to predict subsequent cerebrovascular events,followed by model 2,and finally model 1.These findings indicate that combining retinal venular or arteriolar diameter with traditional risk factors could improve the prediction of recurrent cerebrovascular events in patients with acute ischemic stroke,and that retinal imaging could be a useful and non-invasive method for identifying high-risk patients who require closer monitoring and more aggressive management. 展开更多
关键词 acute ischemic stroke arteriolar cerebrovascular events DIAMETER digital retinal imaging MICROVASCULATURE prediction RECURRENT RETINA venular
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Nadam Fair—A Big Event on the Grassland
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《China & The World Cultural Exchange》 1997年第4期11-12,共2页
关键词 A big event on the Grassland Nadam Fair
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Impact of body mass index on adverse kidney events in diabetes mellitus patients: A systematic-review and meta-analysis 被引量:1
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作者 Jing-Fang Wan Yan Chen +2 位作者 Tian-Hua Yao Ya-Zhou Wu Huan-Zi Dai 《World Journal of Clinical Cases》 SCIE 2024年第3期538-550,共13页
BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However... BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However,no previous meta-analysis has assessed the effects of body mass index(BMI)on adverse kidney events in patients with DM.AIM To determine the impact of BMI on adverse kidney events in patients with DM.METHODS A systematic literature search was performed on the PubMed,ISI Web of Science,Scopus,Ovid,Google Scholar,EMBASE,and BMJ databases.We included trials with the following characteristics:(1)Type of study:Prospective,retrospective,randomized,and non-randomized in design;(2)participants:Restricted to patients with DM aged≥18 years;(3)intervention:No intervention;and(4)kidney adverse events:Onset of diabetic kidney disease[estimated glomerular filtration rate(eGFR)of<60 mL/min/1.73 m2 and/or microalbuminuria value of≥30 mg/g Cr],serum creatinine increase of more than double the baseline or end-stage renal disease(eGFR<15 mL/min/1.73 m2 or dialysis),or death.RESULTS Overall,11 studies involving 801 patients with DM were included.High BMI(≥25 kg/m2)was significantly associated with higher blood pressure(BP)[systolic BP by 0.20,95%confidence interval(CI):0.15–0.25,P<0.00001;diastolic BP by 0.21 mmHg,95%CI:0.04–0.37,P=0.010],serum albumin,triglycerides[standard mean difference(SMD)=0.35,95%CI:0.29–0.41,P<0.00001],low-density lipoprotein(SMD=0.12,95%CI:0.04–0.20,P=0.030),and lower high-density lipoprotein(SMD=–0.36,95%CI:–0.51 to–0.21,P<0.00001)in patients with DM compared with those with low BMIs(<25 kg/m2).Our analysis showed that high BMI was associated with a higher risk ratio of adverse kidney events than low BMI(RR:1.22,95%CI:1.01–1.43,P=0.036).CONCLUSION The present analysis suggested that high BMI was a risk factor for adverse kidney events in patients with DM. 展开更多
关键词 Obesity Body mass index Diabetes mellitus Adverse kidney events Systematic-review META-ANALYSIS
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Sex and racial disparities in non-alcoholic fatty liver disease-related cardiovascular events: National inpatient sample analysis (2019) 被引量:2
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作者 Rupak Desai Ali Tariq Alvi +5 位作者 Advait Vasavada Yashwitha Sai Pulakurthi Bhavin Patel Adil Sarvar Mohammed Shreyans Doshi Ikechukwu Ogbu 《World Journal of Cardiology》 2024年第3期137-148,共12页
BACKGROUND Non-alcoholic fatty liver disease(NAFLD)increases cardiovascular disease(CVD)risk irrespective of other risk factors.However,large-scale cardiovascular sex and race differences are poorly understood.AIM To ... BACKGROUND Non-alcoholic fatty liver disease(NAFLD)increases cardiovascular disease(CVD)risk irrespective of other risk factors.However,large-scale cardiovascular sex and race differences are poorly understood.AIM To investigate the relationship between NAFLD and major cardiovascular and cerebrovascular events(MACCE)in subgroups using a nationally representative United States inpatient sample.METHODS We examined National Inpatient Sample(2019)to identify adult hospitalizations with NAFLD by age,sex,and race using ICD-10-CM codes.Clinical and demographic characteristics,comorbidities,and MACCE-related mortality,acute myocardial infarction(AMI),cardiac arrest,and stroke were compared in NAFLD cohorts by sex and race.Multivariable regression analyses were adjusted for sociodemographic characteristics,hospitalization features,and comorbidities.RESULTS We examined 409130 hospitalizations[median 55(IQR 43-66)years]with NFALD.NAFLD was more common in females(1.2%),Hispanics(2%),and Native Americans(1.9%)than whites.Females often reported non-elective admissions,Medicare enrolment,the median age of 55(IQR 42-67),and poor income.Females had higher obesity and uncomplicated diabetes but lower hypertension,hyperlipidemia,and complicated diabetes than males.Hispanics had a median age of 48(IQR 37-60),were Medicaid enrollees,and had non-elective admissions.Hispanics had greater diabetes and obesity rates than whites but lower hypertension and hyperlipidemia.MACCE,all-cause mortality,AMI,cardiac arrest,and stroke were all greater in elderly individuals(P<0.001).MACCE,AMI,and cardiac arrest were more common in men(P<0.001).Native Americans(aOR 1.64)and Asian Pacific Islanders(aOR 1.18)had higher all-cause death risks than whites.CONCLUSION Increasing age and male sex link NAFLD with adverse MACCE outcomes;Native Americans and Asian Pacific Islanders face higher mortality,highlighting a need for tailored interventions and care. 展开更多
关键词 Non-alcoholic fatty liver disease Cardiovascular disease Major cardiovascular and cerebrovascular events Sex/gender disparities MORTALITY
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Predicting major adverse cardiovascular events after orthotopic liver transplantation using a supervised machine learning model:A cohort study 被引量:1
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作者 Jonathan Soldera Leandro Luis Corso +8 位作者 Matheus Machado Rech Vinícius Remus Ballotin Lucas Goldmann Bigarella Fernanda Tomé Nathalia Moraes Rafael Sartori Balbinot Santiago Rodriguez Ajacio Bandeira de Mello Brandão Bruno Hochhegger 《World Journal of Hepatology》 2024年第2期193-210,共18页
BACKGROUND Liver transplant(LT)patients have become older and sicker.The rate of post-LT major adverse cardiovascular events(MACE)has increased,and this in turn raises 30-d post-LT mortality.Noninvasive cardiac stress... BACKGROUND Liver transplant(LT)patients have become older and sicker.The rate of post-LT major adverse cardiovascular events(MACE)has increased,and this in turn raises 30-d post-LT mortality.Noninvasive cardiac stress testing loses accuracy when applied to pre-LT cirrhotic patients.AIM To assess the feasibility and accuracy of a machine learning model used to predict post-LT MACE in a regional cohort.METHODS This retrospective cohort study involved 575 LT patients from a Southern Brazilian academic center.We developed a predictive model for post-LT MACE(defined as a composite outcome of stroke,new-onset heart failure,severe arrhythmia,and myocardial infarction)using the extreme gradient boosting(XGBoost)machine learning model.We addressed missing data(below 20%)for relevant variables using the k-nearest neighbor imputation method,calculating the mean from the ten nearest neighbors for each case.The modeling dataset included 83 features,encompassing patient and laboratory data,cirrhosis complications,and pre-LT cardiac assessments.Model performance was assessed using the area under the receiver operating characteristic curve(AUROC).We also employed Shapley additive explanations(SHAP)to interpret feature impacts.The dataset was split into training(75%)and testing(25%)sets.Calibration was evaluated using the Brier score.We followed Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis guidelines for reporting.Scikit-learn and SHAP in Python 3 were used for all analyses.The supplementary material includes code for model development and a user-friendly online MACE prediction calculator.RESULTS Of the 537 included patients,23(4.46%)developed in-hospital MACE,with a mean age at transplantation of 52.9 years.The majority,66.1%,were male.The XGBoost model achieved an impressive AUROC of 0.89 during the training stage.This model exhibited accuracy,precision,recall,and F1-score values of 0.84,0.85,0.80,and 0.79,respectively.Calibration,as assessed by the Brier score,indicated excellent model calibration with a score of 0.07.Furthermore,SHAP values highlighted the significance of certain variables in predicting postoperative MACE,with negative noninvasive cardiac stress testing,use of nonselective beta-blockers,direct bilirubin levels,blood type O,and dynamic alterations on myocardial perfusion scintigraphy being the most influential factors at the cohort-wide level.These results highlight the predictive capability of our XGBoost model in assessing the risk of post-LT MACE,making it a valuable tool for clinical practice.CONCLUSION Our study successfully assessed the feasibility and accuracy of the XGBoost machine learning model in predicting post-LT MACE,using both cardiovascular and hepatic variables.The model demonstrated impressive performance,aligning with literature findings,and exhibited excellent calibration.Notably,our cautious approach to prevent overfitting and data leakage suggests the stability of results when applied to prospective data,reinforcing the model’s value as a reliable tool for predicting post-LT MACE in clinical practice. 展开更多
关键词 Liver transplantation Major adverse cardiac events Machine learning Myocardial perfusion imaging Stress test
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BIG评分对接受去骨瓣减压术的中重度创伤性脑损伤儿童早期脑功能的预测价值
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作者 徐静静 党红星 《临床医学进展》 2024年第4期2631-2640,共10页
目的:探讨BIG评分(由格拉斯哥评分、国际标准化比值、碱剩余组成)对接受去骨瓣减压术(DC)的中重度创伤性脑损伤(TBI)患儿脑功能早期预后的预测价值。方法:回顾性分析2014年3月至2023年7月于我院接受DC治疗的所有中重度TBI患儿,以出院时... 目的:探讨BIG评分(由格拉斯哥评分、国际标准化比值、碱剩余组成)对接受去骨瓣减压术(DC)的中重度创伤性脑损伤(TBI)患儿脑功能早期预后的预测价值。方法:回顾性分析2014年3月至2023年7月于我院接受DC治疗的所有中重度TBI患儿,以出院时儿童脑功能分类(PCPC)为结局,分为预后良好组(PCPC 1~2)和预后不良组(PCPC 3~6)。通过病历资料回顾,提取患儿的临床信息,并使用Logistic回归分析评估BIG评分的预测价值。结果:共纳入55例接受DC治疗的中重度TBI患儿,其中25例出院时脑功能良好,30例预后不良(包括9例死亡)。患儿入院时的高BIG评分(p < 0.001)、瞳孔对光反射差(p = 0.027),存在失血性休克(p = 0.042)及多发伤(p = 0.043)、脑水肿(p = 0.007),高血糖(p = 0.042)、高乳酸血症(p = 0.029)均与出院时脑功能不良相关。Logistic回归分析显示,入院时的高BIG评分是出院时脑功能不良的独立危险因素。ROC曲线分析确定的最佳BIG评分阈值为17.5,以此预测不良预后的敏感性为66.7%,特异性为88.0%。结论:接受DC的中重度TBI患儿出院时的总体脑功能不良比例为54.5%。入院时的BIG评分能够预测这些患儿出院时的早期脑功能预后,具有较高的敏感性和特异性。 展开更多
关键词 创伤性脑损伤 去骨瓣减压术 big评分 儿童 预后
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EVENT联合思政教学模式在提升护理实习生人文关怀能力中的应用研究 被引量:1
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作者 柳丹 王芷彤 《卫生职业教育》 2024年第5期68-71,共4页
目的探讨EVENT联合思政教学模式在提升护理实习生人文关怀能力中的应用效果。方法随机抽取2022年7月至2023年7月在甲状腺疝小儿外科进行实习的护生为研究对象,对照组采用常规教学模式,实验组在对照组的基础上采用EVENT联合思政教学模式... 目的探讨EVENT联合思政教学模式在提升护理实习生人文关怀能力中的应用效果。方法随机抽取2022年7月至2023年7月在甲状腺疝小儿外科进行实习的护生为研究对象,对照组采用常规教学模式,实验组在对照组的基础上采用EVENT联合思政教学模式。比较两组理论成绩、自主学习能力、工作投入度及人文关怀能力。结果教学后,实验组理论成绩、自主学习能力、工作投入度及人文关怀能力均高于对照组(P<0.05)。结论EVENT联合思政教学模式能提升护理实习生理论成绩、自主学习能力、工作投入度及人文关怀能力,值得在教学中推广应用。 展开更多
关键词 event教学模式 思政教学 护理实习生 人文关怀能力
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A Time Series Short-Term Prediction Method Based on Multi-Granularity Event Matching and Alignment
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作者 Haibo Li Yongbo Yu +1 位作者 Zhenbo Zhao Xiaokang Tang 《Computers, Materials & Continua》 SCIE EI 2024年第1期653-676,共24页
Accurate forecasting of time series is crucial across various domains.Many prediction tasks rely on effectively segmenting,matching,and time series data alignment.For instance,regardless of time series with the same g... Accurate forecasting of time series is crucial across various domains.Many prediction tasks rely on effectively segmenting,matching,and time series data alignment.For instance,regardless of time series with the same granularity,segmenting them into different granularity events can effectively mitigate the impact of varying time scales on prediction accuracy.However,these events of varying granularity frequently intersect with each other,which may possess unequal durations.Even minor differences can result in significant errors when matching time series with future trends.Besides,directly using matched events but unaligned events as state vectors in machine learning-based prediction models can lead to insufficient prediction accuracy.Therefore,this paper proposes a short-term forecasting method for time series based on a multi-granularity event,MGE-SP(multi-granularity event-based short-termprediction).First,amethodological framework for MGE-SP established guides the implementation steps.The framework consists of three key steps,including multi-granularity event matching based on the LTF(latest time first)strategy,multi-granularity event alignment using a piecewise aggregate approximation based on the compression ratio,and a short-term prediction model based on XGBoost.The data from a nationwide online car-hailing service in China ensures the method’s reliability.The average RMSE(root mean square error)and MAE(mean absolute error)of the proposed method are 3.204 and 2.360,lower than the respective values of 4.056 and 3.101 obtained using theARIMA(autoregressive integratedmoving average)method,as well as the values of 4.278 and 2.994 obtained using k-means-SVR(support vector regression)method.The other experiment is conducted on stock data froma public data set.The proposed method achieved an average RMSE and MAE of 0.836 and 0.696,lower than the respective values of 1.019 and 0.844 obtained using the ARIMA method,as well as the values of 1.350 and 1.172 obtained using the k-means-SVR method. 展开更多
关键词 Time series short-term prediction multi-granularity event ALIGNMENT event matching
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Grassland-type ecosystem stability in China differs under the influence of drought and wet events
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作者 CAO Wenyu BAI Jianjun YU Leshan 《Journal of Arid Land》 SCIE CSCD 2024年第5期615-631,共17页
Ecological stability is a core issue in ecological research and holds significant implications forhumanity. The increased frequency and intensity of drought and wet climate events resulting from climatechange pose a m... Ecological stability is a core issue in ecological research and holds significant implications forhumanity. The increased frequency and intensity of drought and wet climate events resulting from climatechange pose a major threat to global ecological stability. Variations in stability among different ecosystemshave been confirmed, but it remains unclear whether there are differences in stability within the sameterrestrial vegetation ecosystem under the influence of climate events in different directions and intensities.China's grassland ecosystem includes most grassland types and is a good choice for studying this issue.This study used the Standardized Precipitation Evapotranspiration Index-12 (SPEI-12) to identify thedirections and intensities of different types of climate events, and based on Normalized DifferenceVegetation Index (NDVI), calculated the resistance and resilience of different grassland types for 30consecutive years from 1990 to 2019 (resistance and resilience are important indicators to measurestability). Based on a traditional regression model, standardized methods were integrated to analyze theimpacts of the intensity and duration of drought and wet events on vegetation stability. The resultsshowed that meadow steppe exhibited the highest stability, while alpine steppe and desert steppe had thelowest overall stability. The stability of typical steppe, alpine meadow, temperate meadow was at anintermediate level. Regarding the impact of the duration and intensity of climate events on vegetationecosystem stability for the same grassland type, the resilience of desert steppe during drought was mainlyaffected by the duration. In contrast, the impact of intensity was not significant. However, alpine steppewas mainly affected by intensity in wet environments, and duration had no significant impact. Ourconclusions can provide decision support for the future grassland ecosystem governance. 展开更多
关键词 grassland ecosystem stability resistance RESILIENCE different climate types drought climate event wet climate event
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IJO Press Event Photos
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《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第10期F0003-F0004,共2页
Pof.G.H.Naumamn,Pesidet ofICO and Pror Bruce Spivey,Peidenr-Elet of iCO moct Prof Xiu-Wen Hu midle Chier Eaitor of JOIES a Woc 2006 in Sao Paulo,Brazil.
关键词 BRUCE event Brazil
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Big Data Access Control Mechanism Based on Two-Layer Permission Decision Structure
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作者 Aodi Liu Na Wang +3 位作者 Xuehui Du Dibin Shan Xiangyu Wu Wenjuan Wang 《Computers, Materials & Continua》 SCIE EI 2024年第4期1705-1726,共22页
Big data resources are characterized by large scale, wide sources, and strong dynamics. Existing access controlmechanisms based on manual policy formulation by security experts suffer from drawbacks such as low policy... Big data resources are characterized by large scale, wide sources, and strong dynamics. Existing access controlmechanisms based on manual policy formulation by security experts suffer from drawbacks such as low policymanagement efficiency and difficulty in accurately describing the access control policy. To overcome theseproblems, this paper proposes a big data access control mechanism based on a two-layer permission decisionstructure. This mechanism extends the attribute-based access control (ABAC) model. Business attributes areintroduced in the ABAC model as business constraints between entities. The proposed mechanism implementsa two-layer permission decision structure composed of the inherent attributes of access control entities and thebusiness attributes, which constitute the general permission decision algorithm based on logical calculation andthe business permission decision algorithm based on a bi-directional long short-term memory (BiLSTM) neuralnetwork, respectively. The general permission decision algorithm is used to implement accurate policy decisions,while the business permission decision algorithm implements fuzzy decisions based on the business constraints.The BiLSTM neural network is used to calculate the similarity of the business attributes to realize intelligent,adaptive, and efficient access control permission decisions. Through the two-layer permission decision structure,the complex and diverse big data access control management requirements can be satisfied by considering thesecurity and availability of resources. Experimental results show that the proposed mechanism is effective andreliable. In summary, it can efficiently support the secure sharing of big data resources. 展开更多
关键词 big data access control data security BiLSTM
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