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SlWRKY30 and SlWRKY81 synergistically modulate tomato immunity to Ralstonia solanacearum by directly regulating SlPR-STH2 被引量:2
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作者 Fengfeng Dang Jinhui Lin +5 位作者 Yajing Li Ruoyun Jiang Yudong Fang Fei Ding Shuilin He Yanfeng Wang 《Horticulture Research》 SCIE CSCD 2023年第5期99-111,共13页
Bacterial wilt is a devastating disease of tomato(Solanum lycopersicum)caused by Ralstonia solanacearum that severely threatens tomato production.Group III WRKY transcription factors(TFs)are implicated in the plant re... Bacterial wilt is a devastating disease of tomato(Solanum lycopersicum)caused by Ralstonia solanacearum that severely threatens tomato production.Group III WRKY transcription factors(TFs)are implicated in the plant response to pathogen infection;however,their roles in the response of tomato to R.solanacearum infection(RSI)remain largely unexplored.Here,we report the crucial role of SlWRKY30,a group III SlWRKY TF,in the regulation of tomato response to RSI.SlWRKY30 was strongly induced by RSI.SlWRKY30 overexpression reduced tomato susceptibility to RSI,and also increased H2O2 accumulation and cell necrosis,suggesting that SlWRKY30 positively regulates tomato resistance to RSI.RNA sequencing and reverse transcription–quantitative PCR revealed that SlWRKY30 overexpression significantly upregulated pathogenesis-related protein(SlPR-STH2)genes SlPR-STH2a,SlPR-STH2b,SlPR-STH2c,and SlPR-STH2d(hereafter SlPR-STH2a/b/c/d)in tomato,and these SlPR-STH2 genes were directly targeted by SlWRKY30.Moreover,four group III WRKY proteins(SlWRKY52,SlWRKY59,SlWRKY80,and SlWRKY81)interacted with SlWRKY30,and SlWRKY81 silencing increased tomato susceptibility to RSI.Both SlWRKY30 and SlWRKY81 activated SlPR-STH2a/b/c/d expression by directly binding to their promoters.Taking these results together,SlWRKY30 and SlWRKY81 synergistically regulate resistance to RSI by activating SlPR-STH2a/b/c/d expression in tomato.Our results also highlight the potential of SlWRKY30 to improve tomato resistance to RSI via genetic manipulations. 展开更多
关键词 directly SYNERGISTIC IMMUNITY
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Anisotropic time-dependent behaviors of shale under direct shearing and associated empirical creep models 被引量:2
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作者 Yachen Xie Michael Z.Hou +1 位作者 Hejuan Liu Cunbao Li 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第4期1262-1279,共18页
Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging issue.In this context,we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.0°,... Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging issue.In this context,we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.0°,30°,45°,60°,and 90°),under multiple levels of direct shearing for the first time.The results show that the anisotropic creep of shale exhibits a significant stress-dependent behavior.Under a low shear stress,the creep compliance of shale increases linearly with the logarithm of time at all bedding orientations,and the increase depends on the bedding orientation and creep time.Under high shear stress conditions,the creep compliance of shale is minimal when the bedding orientation is 0°,and the steady-creep rate of shale increases significantly with increasing bedding orientations of 30°,45°,60°,and 90°.The stress-strain values corresponding to the inception of the accelerated creep stage show an increasing and then decreasing trend with the bedding orientation.A semilogarithmic model that could reflect the stress dependence of the steady-creep rate while considering the hardening and damage process is proposed.The model minimizes the deviation of the calculated steady-state creep rate from the observed value and reveals the behavior of the bedding orientation's influence on the steady-creep rate.The applicability of the five classical empirical creep models is quantitatively evaluated.It shows that the logarithmic model can well explain the experimental creep strain and creep rate,and it can accurately predict long-term shear creep deformation.Based on an improved logarithmic model,the variations in creep parameters with shear stress and bedding orientations are discussed.With abovementioned findings,a mathematical method for constructing an anisotropic shear creep model of shale is proposed,which can characterize the nonlinear dependence of the anisotropic shear creep behavior of shale on the bedding orientation. 展开更多
关键词 Rock anisotropy direct shear creep Creep compliance Steady-creep rate Empirical model Creep constitutive model
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Early Triassic Volcanic Rocks in the Western Yarlung Zangbo Suture Zone:Implications for the Opening of the Neo-Tethys Ocean 被引量:1
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作者 HE Juan LI Yalin +4 位作者 HOU Yunling ZHOU Aorigele WEI Yushuai CHEN Xi DAI Jingen 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2024年第2期324-336,共13页
In this study,zircon U-Pb dating of volcanic rocks from the Zhongba ophiolite of the Yarlung Zangbo Suture Zone(YZSZ)in southern Xizang(Tibet)yielded an age of 247±3 Ma.According to whole rock geochemical and Sr-... In this study,zircon U-Pb dating of volcanic rocks from the Zhongba ophiolite of the Yarlung Zangbo Suture Zone(YZSZ)in southern Xizang(Tibet)yielded an age of 247±3 Ma.According to whole rock geochemical and Sr-NdPb isotopic data,the Early Triassic samples could be divided into two groups:Group 1 with P-MORB affinity,showing initial^(87)Sr/^(86)Sr ratios of 0.70253–0.70602,ε_(Nd)(t)values of 4.2–5.3,(^(206)Pb/^(204)Pb)_(t)ratios of 16.353–18.222,(^(207)Pb/^(204)Pb)_(t)ratios of 15.454–15.564,and(^(208)Pb/^(204)Pb)_(t)ratios of 35.665–38.136;Group 2 with OIB affinity,showing initial^(87)Sr/^(86)Sr ratios of 0.70249–0.70513,ε_(Nd)(t)values of 4.4–4.9,(^(206)Pb/^(204)Pb)_(t)ratios of 17.140–18.328,(^(207)Pb/^(204)Pb)_(t)ratios of 15.491–15.575,and(^(208)Pb/^(204)Pb)_(t)ratios of 36.051–38.247.Group 2 rocks formed by partial melting of the mantle source enriched by a former plume,and assimilated continental crustal material during melt ascension.The formation of Group 1 rocks corresponds to the mixing of OIB melts,with the same components as Group 2 and N-MORBs.The Zhongba Early Triassic rocks belong to the continental margin type ophiolite and formed in the continental–oceanic transition zone during the initial opening of the Neo-Tethys in southern Xizang(Tibet). 展开更多
关键词 RIFT Early Triassic magmatism Yarlung Zangbo Suture zone NEO-TETHYS Southern Xizang TIBET
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Complication rates after direct anterior vs posterior approach for hip hemiarthroplasty in elderly individuals with femoral neck fractures 被引量:2
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作者 Tatiana Charles Nicolas Bloemers +1 位作者 Bilal Kapanci Marc Jayankura 《World Journal of Orthopedics》 2024年第1期22-29,共8页
BACKGROUND Dislocation rates after hemiarthroplasty reportedly vary from 1%to 17%.This serious complication is associated with increased morbidity and mortality rates.Approaches to this surgery are still debated,with ... BACKGROUND Dislocation rates after hemiarthroplasty reportedly vary from 1%to 17%.This serious complication is associated with increased morbidity and mortality rates.Approaches to this surgery are still debated,with no consensus regarding the superiority of any single approach.AIM To compare early postoperative complications after implementing the direct anterior and posterior approaches(PL)for hip hemiarthroplasty after femoral neck fractures.METHODS This is a comparative,retrospective,single-center cohort study conducted at a university hospital.Between March 2008 and December 2018,273 patients(a total of 280 hips)underwent bipolar hemiarthroplasties(n=280)for displaced femoral neck fractures using either the PL(n=171)or the minimally invasive direct anterior approach(DAA)(n=109).The choice of approach was related to the surgeons’practices;the implant types were similar and unrelated to the approach.Dislocation rates and other complications were reviewed after a minimum followup of 6 mo.RESULTS Both treatment groups had similarly aged patients(mean age:82 years),sex ratios,patient body mass indexes,and patient comorbidities.Surgical data(surgery delay time,operative time,and blood loss volume)did not differ significantly between the groups.The 30 d mortality rate was higher in the PL group(9.9%)than in the DAA group(3.7%),but the difference was not statistically significant(P=0.052).Among the one-month survivors,a significantly higher rate of dislocation was observed in the PL group(14/154;9.1%)than in the DAA group(0/105;0%)(P=0.002).Of the 14 patients with dislocation,8 underwent revision surgery for recurrent instability(posterior group),and one of them had 2 additional procedures due to a deep infection.The rate of other complications(e.g.,perioperative and early postoperative periprosthetic fractures and infection-related complications)did not differ significantly between the groups.CONCLUSION These findings suggest that the DAA to bipolar hemiarthroplasty for patients with femoral neck fractures is associated with a lower dislocation rate(<1%)than the PL. 展开更多
关键词 HEMIARTHROPLASTY Femoral neck fracture direct anterior approach Posterior approach DISLOCATION MORTALITY
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Vibration Control of A Flexible Marine Riser System Subject to Input Dead Zone and Extraneous Disturbances 被引量:1
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作者 ZHOU Li WANG Guo-rong WAN Min 《China Ocean Engineering》 SCIE EI CSCD 2024年第2期271-284,共14页
An observer-based adaptive backstepping boundary control is proposed for vibration control of flexible offshore riser systems with unknown nonlinear input dead zone and uncertain environmental disturbances.The control... An observer-based adaptive backstepping boundary control is proposed for vibration control of flexible offshore riser systems with unknown nonlinear input dead zone and uncertain environmental disturbances.The control algorithm can update the control law online through real-time data to make the controller adapt to the environment and improve the control precision.Specifically,based on the adaptive backstepping framework,virtual control laws and Lyapunov functions are designed for each subsystem.Three direction interference observers are designed to track the timevarying boundary disturbance.On this basis,the inverse of the dead zone and linear state transformation are used to compensate for the original system and eliminate the adverse effects of the dead zone.In addition,the stability of the closed-loop system is proven by Lyapunov stability theory.All the system states are bounded,and the vibration offset of the riser converges to a small area of the initial position.Finally,four examples of flexible marine risers are simulated in MATLAB to verify the effectiveness of the proposed controller. 展开更多
关键词 adaptive backstepping control disturbance observer flexible marine riser input dead zone vibration control
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Review on laser directed energy deposited aluminum alloys 被引量:2
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作者 Tian-Shu Liu Peng Chen +7 位作者 Feng Qiu Hong-Yu Yang Nicholas Tan Yew Jin Youxiang Chew Di Wang Ruidi Li Qi-Chuan Jiang Chaolin Tan 《International Journal of Extreme Manufacturing》 SCIE EI CAS CSCD 2024年第2期84-131,共48页
Lightweight aluminum(Al)alloys have been widely used in frontier fields like aerospace and automotive industries,which attracts great interest in additive manufacturing(AM)to process high-value Al parts.As a mainstrea... Lightweight aluminum(Al)alloys have been widely used in frontier fields like aerospace and automotive industries,which attracts great interest in additive manufacturing(AM)to process high-value Al parts.As a mainstream AM technique,laser-directed energy deposition(LDED)shows good scalability to meet the requirements for large-format component manufacturing and repair.However,LDED Al alloys are highly challenging due to their inherent poor printability(e.g.low laser absorption,high oxidation sensitivity and cracking tendency).To further promote the development of LDED high-performance Al alloys,this review offers a deep understanding of the challenges and strategies to improve printability in LDED Al alloys.The porosity,cracking,distortion,inclusions,element evaporation and resultant inferior mechanical properties(worse than laser powder bed fusion)are the key challenges in LDED Al alloys.Processing parameter optimizations,in-situ alloy design,reinforcing particle addition and field assistance are the efficient approaches to improving the printability and performance of LDED Al alloys.The underlying correlations between processes,alloy innovation,characteristic microstructures,and achievable performances in LDED Al alloys are discussed.The benchmark mechanical properties and primary strengthening mechanism of LDED Al alloys are summarized.This review aims to provide a critical and in-depth evaluation of current progress in LDED Al alloys.Future opportunities and perspectives in LDED high-performance Al alloys are also outlined. 展开更多
关键词 additive manufacturing laser directed energy deposition(LDED) aluminum alloys PRINTABILITY aluminum matrix composite auxiliary fields mechanical properties
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Post-transcriptional mechanisms controlling neurogenesis and direct neuronal reprogramming 被引量:1
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作者 Elsa Papadimitriou Dimitra Thomaidou 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第9期1929-1939,共11页
Neurogenesis is a tightly regulated process in time and space both in the developing embryo and in adult neurogenic niches.A drastic change in the transcriptome and proteome of radial glial cells or neural stem cells ... Neurogenesis is a tightly regulated process in time and space both in the developing embryo and in adult neurogenic niches.A drastic change in the transcriptome and proteome of radial glial cells or neural stem cells towards the neuronal state is achieved due to sophisticated mechanisms of epigenetic,transcriptional,and post-transcriptional regulation.Understanding these neurogenic mechanisms is of major importance,not only for shedding light on very complex and crucial developmental processes,but also for the identification of putative reprogramming factors,that harbor hierarchically central regulatory roles in the course of neurogenesis and bare thus the capacity to drive direct reprogramming towards the neuronal fate.The major transcriptional programs that orchestrate the neurogenic process have been the focus of research for many years and key neurogenic transcription factors,as well as repressor complexes,have been identified and employed in direct reprogramming protocols to convert non-neuronal cells,into functional neurons.The post-transcriptional regulation of gene expression during nervous system development has emerged as another important and intricate regulatory layer,strongly contributing to the complexity of the mechanisms controlling neurogenesis and neuronal function.In particular,recent advances are highlighting the importance of specific RNA binding proteins that control major steps of mRNA life cycle during neurogenesis,such as alternative splicing,polyadenylation,stability,and translation.Apart from the RNA binding proteins,microRNAs,a class of small non-coding RNAs that block the translation of their target mRNAs,have also been shown to play crucial roles in all the stages of the neurogenic process,from neural stem/progenitor cell proliferation,neuronal differentiation and migration,to functional maturation.Here,we provide an overview of the most prominent post-transcriptional mechanisms mediated by RNA binding proteins and microRNAs during the neurogenic process,giving particular emphasis on the interplay of specific RNA binding proteins with neurogenic microRNAs.Taking under consideration that the molecular mechanisms of neurogenesis exert high similarity to the ones driving direct neuronal reprogramming,we also discuss the current advances in in vitro and in vivo direct neuronal reprogramming approaches that have employed microRNAs or RNA binding proteins as reprogramming factors,highlighting the so far known mechanisms of their reprogramming action. 展开更多
关键词 direct neuronal reprogramming in vivo glia-to-neuron conversion microRNAs NEUROGENESIS post-transcriptional regulation RNA binding proteins
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One-year results for myopia control of orthokeratology with different back optic zone diameters: a randomized trial using a novel multispectral-based topographer 被引量:1
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作者 Wen-Ting Tang Xiang-Ning Luo +4 位作者 Wen-Jing Zhao Jia Liao Xin-Yue Xu Hui-Dan Zhang Li Zhang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第2期324-330,共7页
AIM:To present the 1-year results of a prospective cohort study investigating the efficacy,potential mechanism,and safety of orthokeratology(ortho-k)with different back optic zone diameters(BOZD)for myopia control in ... AIM:To present the 1-year results of a prospective cohort study investigating the efficacy,potential mechanism,and safety of orthokeratology(ortho-k)with different back optic zone diameters(BOZD)for myopia control in children.METHODS:This randomized clinical study was performed between Dec.2020 and Dec.2021.Participants were randomly assigned to three groups wearing ortho-k:5 mm BOZD(5-MM group),5.5 mm BOZD(5.5-MM group),and 6 mm BOZD(6-MM group).The 1-year data were recorded,including axial length,relative peripheral refraction(RPR,measured by multispectral refractive topography,MRT),and visual quality.The contrast sensitivity(CS)was evaluated by CSV-1000 instrument with spatial frequencies of 3,6,12,and 18 cycles/degree(c/d);the corneal higher-order aberrations(HOAs)were measured by iTrace aberration analyzer.The one-way ANOVA was performed to assess the differences between the three groups.The correlation between the change in AL and RPR was calculated by Pearson’s correlation coefficient.RESULTS:The 1-year results of 20,21,and 21 subjects in the 5-MM,5.5-MM,and 6-MM groups,respectively,were presented.There were no statistical differences in baseline age,sex,or ocular parameters between the three groups(all P>0.05).At the 1-year visit,the 5-MM group had lower axial elongation than the 6-MM group(0.07±0.09 vs 0.18±0.11 mm,P=0.001).The 5-MM group had more myopic total RPR(TRPR,P=0.014),with RPR in the 15°–30°(RPR 15–30,P=0.015),30°–45°(RPR 30–45,P=0.011),temporal(RPR-T,P=0.008),and nasal area(RPR-N,P<0.001)than the 6-MM group.RPR 15–30 in the 5.5-MM group was more myopic than that in the 6-MM group(P=0.002),and RPR-N in the 5-MM group was more myopic than that in the 5.5-MM group(P<0.001).There were positive correlations between the axial elongation and the change in TRPR(r=0.756,P<0.001),RPR 15–30(r=0.364,P=0.004),RPR 30–45(r=0.306,P=0.016),and RPR-N(r=0.253,P=0.047).The CS decreased at 3 c/d(P<0.001),and the corneal HOAs increased in the 5-MM group(P=0.030).CONCLUSION:Ortho-k with 5 mm BOZD can control myopia progression more effectively.The mechanism may be associated with greater myopic shifts in RPR. 展开更多
关键词 relative peripheral refraction ORTHOKERATOLOGY MYOPIA back optic zone diameter axial length multispectral refractive topography
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Kinetics of the direct reaction between ozone and phenol by high-gravity intensified heterogeneous catalytic ozonation
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作者 Kechang Gao Shengjuan Shao +3 位作者 Zhixing Li Jiaxin Jing Weizhou Jiao Youzhi Liu 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第1期317-323,共7页
In this study,high-gravity intensified heterogeneous catalytic ozonation is utilized for treatment of phenol-containing wastewater,and the kinetics of the direct reaction between ozone and phenol in the presence of ex... In this study,high-gravity intensified heterogeneous catalytic ozonation is utilized for treatment of phenol-containing wastewater,and the kinetics of the direct reaction between ozone and phenol in the presence of excess tertiary butanol(TBA)is investigated.It is revealed that the direct reaction between ozone and phenol in the rotating packed bed(RPB)follows the pseudo-first-order kinetics with a reaction rate constant higher than that in the conventional bubbling reactor(BR).Under different conditions of temperature,initial pH,high-gravity factor,and gaseous ozone concentration,the apparent reaction rate constant varies in the range of 0.0160–0.115 min-1.An empirical power-exponential model is established to characterize the effects of these parameters on the direct reaction between ozone and phenol by high-gravity intensified heterogeneous catalytic ozonation. 展开更多
关键词 High-gravity technique Heterogeneous catalysis Ozone PHENOL Kinetics of the direct reaction
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New direction for surgery:Super minimally invasive surgery 被引量:1
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作者 En-Qiang Linghu 《World Journal of Gastroenterology》 SCIE CAS 2024年第12期1676-1679,共4页
The top goal of modern medicine is treating disease without destroying organ structures and making patients as healthy as they were before their sickness.Minimally invasive surgery(MIS)has dominated the surgical realm... The top goal of modern medicine is treating disease without destroying organ structures and making patients as healthy as they were before their sickness.Minimally invasive surgery(MIS)has dominated the surgical realm because of its lesser invasiveness.However,changes in anatomical structures of the body and reconstruction of internal organs or different organs are common after traditional surgery or MIS,decreasing the quality of life of patients post-operation.Thus,I propose a new treatment mode,super MIS(SMIS),which is defined as“curing a disease or lesion which used to be treated by MIS while preserving the integrity of the organs”.In this study,I describe the origin,definition,operative channels,advantages,and future perspectives of SMIS. 展开更多
关键词 Super minimally invasive surgery Minimally invasive surgery Treatment mode Traditional Surgery New direction for surgery
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Two-photon live imaging of direct glia-to-neuron conversion in the mouse cortex 被引量:1
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作者 Zongqin Xiang Shu He +13 位作者 Rongjie Chen Shanggong Liu Minhui Liu Liang Xu Jiajun Zheng Zhouquan Jiang Long Ma Ying Sun Yongpeng Qin Yi Chen Wen Li Xiangyu Wang Gong Chen Wenliang Lei 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第8期1781-1788,共8页
Over the past decade,a growing number of studies have reported transcription factor-based in situ reprogramming that can directly conve rt endogenous glial cells into functional neurons as an alternative approach for ... Over the past decade,a growing number of studies have reported transcription factor-based in situ reprogramming that can directly conve rt endogenous glial cells into functional neurons as an alternative approach for n euro regeneration in the adult mammalian central ne rvous system.Howeve r,many questions remain regarding how a terminally differentiated glial cell can transform into a delicate neuron that forms part of the intricate brain circuitry.In addition,concerns have recently been raised around the absence of astrocyte-to-neuron conversion in astrocytic lineage-tra cing mice.In this study,we employed repetitive two-photon imaging to continuously capture the in situ astrocyte-to-neuron conversion process following ecto pic expression of the neural transcription factor NeuroD1 in both prolife rating reactive astrocytes and lineage-tra ced astrocytes in the mouse cortex.Time-lapse imaging over several wee ks revealed the ste p-by-step transition from a typical astrocyte with numero us short,tapered branches to a typical neuro n with a few long neurites and dynamic growth cones that actively explored the local environment.In addition,these lineage-converting cells were able to migrate ra dially or to ngentially to relocate to suitable positions.Furthermore,two-photon Ca2+imaging and patch-clamp recordings confirmed that the newly generated neuro ns exhibited synchronous calcium signals,repetitive action potentials,and spontaneous synaptic responses,suggesting that they had made functional synaptic connections within local neural circuits.In conclusion,we directly visualized the step-by-step lineage conversion process from astrocytes to functional neurons in vivo and unambiguously demonstrated that adult mammalian brains are highly plastic with respect to their potential for neuro regeneration and neural circuit reconstruction. 展开更多
关键词 astrocyte-to-neuron conversion Ca2+imaging direct lineage conversion GLIA ASTROCYTE in vivo reprogramming lineage-tracing mice NeuroD1 NEURON two-photon imaging
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Tensile strength and failure behavior of rock-mortar interfaces: Direct and indirect measurements 被引量:1
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作者 Ghasem Shams Patrice Rivard Omid Moradian 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第1期41-55,共15页
The tensile strength at the rock-concrete interface is one of the crucial factors controlling the failure mechanisms of structures,such as concrete gravity dams.Despite the critical importance of the failure mechanism... The tensile strength at the rock-concrete interface is one of the crucial factors controlling the failure mechanisms of structures,such as concrete gravity dams.Despite the critical importance of the failure mechanism and tensile strength of rock-concrete interfaces,understanding of these factors remains very limited.This study investigated the tensile strength and fracturing processes at rock-mortar interfaces subjected to direct and indirect tensile loadings.Digital image correlation(DIC)and acoustic emission(AE)techniques were used to monitor the failure mechanisms of specimens subjected to direct tension and indirect loading(Brazilian tests).The results indicated that the direct tensile strength of the rock-mortar specimens was lower than their indirect tensile strength,with a direct/indirect tensile strength ratio of 65%.DIC strain field data and moment tensor inversions(MTI)of AE events indicated that a significant number of shear microcracks occurred in the specimens subjected to the Brazilian test.The presence of these shear microcracks,which require more energy to break,resulted in a higher tensile strength during the Brazilian tests.In contrast,microcracks were predominantly tensile in specimens subjected to direct tension,leading to a lower tensile strength.Spatiotemporal monitoring of the cracking processes in the rock-mortar interfaces revealed that they show AE precursors before failure under the Brazilian test,whereas they show a minimal number of AE events before failure under direct tension.Due to different microcracking mechanisms,specimens tested under Brazilian tests showed lower roughness with flatter fracture surfaces than those tested under direct tension with jagged and rough fracture surfaces.The results of this study shed light on better understanding the micromechanics of damage in the rock-concrete interfaces for a safer design of engineering structures. 展开更多
关键词 Rock-mortar Rock-concrete Moment tensor inversion(MTI) Acoustic emission(AE) Digital image correlation(DIC) Tensile strength direct tensile test Brazilian test
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Advances in seismological methods for characterizing fault zone structure
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作者 Yan Cai Jianping Wu +1 位作者 Yaning Liu Shijie Gao 《Earthquake Science》 2024年第2期122-138,共17页
Large earthquakes frequently occur along complex fault systems.Understanding seismic rupture and long-term fault evolution requires constraining the geometric and material properties of fault zone structures.We provid... Large earthquakes frequently occur along complex fault systems.Understanding seismic rupture and long-term fault evolution requires constraining the geometric and material properties of fault zone structures.We provide a comprehensive overview of recent advancements in seismological methods used to study fault zone structures,including seismic tomography,fault zone seismic wave analysis,and seismicity analysis.Observational conditions limit our current ability to fully characterize fault zones,for example,insufficient imaging resolution to discern small-scale anomalies,incomplete capture of crucial fault zone seismic waves,and limited precision in event location accuracy.Dense seismic arrays can overcome these limitations and enable more detailed investigations of fault zone structures.Moreover,we present new insights into the structure of the Anninghe-Xiaojiang fault zone in the southeastern margin of the Qinghai-Xizang Plateau based on data collected from a dense seismic array.We found that utilizing a dense seismic array can identify small-scale features within fault zones,aiding in the interpretation of fault zone geometry and material properties. 展开更多
关键词 fault zone structure TOMOGRAPHY fault zone wave seismic activity Anninghe-Xiaojiang fault zone
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Dynamic Identification and Evolution of Urban-suburban-rural Transition Zones Based on the Blender of Natural and Humanistic Factors: A Case Study of Chengdu, China
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作者 DENG Wei JIANG Zhenyuan +3 位作者 ZHANG Shaoyao REN Ping ZHANG Hao WANG Zhanyun 《Chinese Geographical Science》 SCIE CSCD 2024年第5期791-809,共19页
Urban-suburban-rural(U-S-R)zones exhibit distinctive transitional characteristics in interaction between human and nature.U-S-R transition zones(U-S-RTZ)are also highlighting the function diversity and landscape heter... Urban-suburban-rural(U-S-R)zones exhibit distinctive transitional characteristics in interaction between human and nature.U-S-R transition zones(U-S-RTZ)are also highlighting the function diversity and landscape heterogeneity across territorial spaces.As a super megacity in western China,Chengdu’s rapid urbanization has driven the evolution of U-S-R spaces,resulting in a sequential structure.To promote the high-quality spatial development of urban-rural region in a structured and efficient manner,it is essential to con-duct a scientific examination of the multidimensional interconnection within the U-S-RTZ framework.By proposing a novel identifica-tion method of U-S-RTZ and taking Chengdu,China as a case study,grounded in a blender of natural and humanistic factors,this study quantitatively delineated and explored the spatial evolutions of U-S-RTZ and stated the optimization orientation and sustainable devel-opment strategies of the production-living-ecological spaces along the U-S-R gradients.The results show that:1)it is suitable for the quantitative analysis of U-S-RTZ by established three-dimensional identification system in this study.2)In 1990-2020,the urban-sub-urban transition zones(U-STZ)in Chengdu have continuously undergone a substantial increase,and the scale of the suburban-rural transition zones(S-RTZ)has continued to expand slightly,while the space of rural-ecological transition zones(R-ETZ)has noticeably compressed.3)The landuse dynamics within U-S-RTZ has gradually increased in 1990-2020.The main direction of landuse transition was from farmland to construction land or woodlands,with the expansion of construction land being the most significant.4)R-ETZ primarily focus on ecological functions,and there is a trade-off relationship between the production-ecological function within the S-RTZ,and in the U-STZ,production-living composite functions are prioritized.This study emphasizes the importance of elastic planning and precise governance within the U-S-RTZ in a rapid urbanization region,particularly highlighting the role of suburbs as landscape corridors and service hubs in urban-rural integration.It elucidates to the practical implications for achieving high-quality development of integrated U-S-R territorial spaces. 展开更多
关键词 transition zone urban-suburban-rural zones spatial identification evolution mechanism Chengdu China
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High-speed directly modulated distributed feedback laser based on detuned loading and photon-photon resonance effect
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作者 张云山 徐逸帆 +3 位作者 郑吉林 李连艳 方涛 陈向飞 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第9期274-281,共8页
A monolithic integrated two-section distributed feedback(TS-DFB)semiconductor laser for high-speed direct modulation is proposed and analyzed theoretically.The grating structure of the TS-DFB laser is designed by the ... A monolithic integrated two-section distributed feedback(TS-DFB)semiconductor laser for high-speed direct modulation is proposed and analyzed theoretically.The grating structure of the TS-DFB laser is designed by the reconstructionequivalent-chirp(REC)technique,which can reduce the manufacturing cost and difficulty,and achieve high wavelength controlling accuracy.The detuned loading effect and the photon-photon resonance(PPR)effect are utilized to enhance the modulation bandwidth of the TS-DFB laser,exceeding 37 GHz,while that of the conventional one-section DFB laser is only 16 GHz.When the bit rate of the non-return-to-zero(NRZ)signal reaches 55 Gb/s,a clear eye diagram with large opening can still be obtained.These results show that the proposed method can enhance the modulation bandwidth of DFB laser significantly. 展开更多
关键词 directly modulated laser(DML) detuned loading effect photon-photon resonance(PPR)effect reconstruction-equivalent-chirp(REC)technique
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Adaptive Integrated Coastal Zone Planning:History,Challenges,Advances,and Perspectives
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作者 WANG Xinyi SU Fenzhen +4 位作者 WANG Xuege PAN Tingting CUI Yikun LYNE Vincent YAN Fengqin 《Chinese Geographical Science》 SCIE CSCD 2024年第4期599-617,共19页
Coastal zones are dynamic,rich environments,now densely populated,and increasingly challenged by human and climatechange pressures.Effective long-term integrated coastal zone planning is needed to ensure sustainable e... Coastal zones are dynamic,rich environments,now densely populated,and increasingly challenged by human and climatechange pressures.Effective long-term integrated coastal zone planning is needed to ensure sustainable environmental protection and economic development.In this study,we reviewed the history of coastal zone planning since its birth in the 1950s based on the literature retrieved from the Web of Science(Core Collection)from 2000–2023,then summarized the tools and spatial allocation methods commonly used in the planning process,and finally proposed potential solutions to the challenges faced.The results show that after decades of development,coastal zone planning has changed from a decentralized activity to a targeted and integrated one,with an increasing emphasis on the ecosystem approach and the use of multiple planning tools.Spatial analysis techniques and environmental modelling software have become increasingly popular.Linear programming and overlay analysis are common approaches when performing spatial optimization,but land-sea interactions and planning in the marine parts still lack in-depth analysis and practical experience.We are also aware that the challenges posed by the integration of administrative hierarchies,scoping and conservation objectives,stakeholder participation,consideration of social dimensions,and climate change are pervasive throughout the planning process.There is an urgent need to develop more flexible and accurate spatial modelling tools,as well as more efficient participatory methods,and to focus on the holistic nature of the land-sea system to create more resilient and sustainable coastal zones. 展开更多
关键词 Integrated Coastal zone Management(ICZM) coastal zone planning spatial optimization ecosystem-based management
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Marginal zone lymphoma with severe rashes: A case report
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作者 Si-Jun Bai Ye Geng +7 位作者 Yi-Nan Gao Cai-Xia Zhang Qian Mi Chen Zhang Jia-Ling Yang Si-Jie He Zhen-YingYan Jian-Xia He 《World Journal of Clinical Cases》 SCIE 2024年第3期565-574,共10页
BACKGROUND Marginal zone lymphoma(MZL)is an indolent subtype of non-Hodgkin lymphoma(NHL),which is rare clinically with severe rashes as the initial symptom.CASE SUMMARY This study reports a case of MZL with generaliz... BACKGROUND Marginal zone lymphoma(MZL)is an indolent subtype of non-Hodgkin lymphoma(NHL),which is rare clinically with severe rashes as the initial symptom.CASE SUMMARY This study reports a case of MZL with generalized skin rashes accompanied by pruritus and purulent discharge.First-line treatment with rituximab combined with zanubrutinib had poor effects.However,after switching to obinutuzumab combined with zanubrutinib,the case was alleviated,and the rashes disappeared.CONCLUSION For patients with advanced stage MZL not benefiting from type I anti-CD20 monoclonal antibody(mAb)combination therapy,switching to a type II anti-CD20 mAb combination regimen may be considered.This approach may provide a new perspective in the treatment of MZL. 展开更多
关键词 Marginal zone lymphoma Mucosa-associated lymphoid tissue Extranodal marginal zone lymphoma Primary cutaneous marginal zone lymphoma Rituximab Obinutuzumab Zanubrutinib Case report
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Preventing brain aging by the artificial enforcement of the unfolded protein response:future directions
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作者 Felipe Cabral-Miranda Claudio Hetz 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期393-394,共2页
As the life expectancy of the world’s population increases,age-related diseases are emerging as one of the greatest problems facing modern society.The onset of dementia and neurodegenerative diseases is strictly depe... As the life expectancy of the world’s population increases,age-related diseases are emerging as one of the greatest problems facing modern society.The onset of dementia and neurodegenerative diseases is strictly dependent on aging as a major risk factor and has a profound impact on various aspects of the lives of individuals and their families. 展开更多
关键词 DISEASES AGING directIONS
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Formation mechanism of fault accommodation zones under combined stress in graben basin:Implications from geomechanical modeling
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作者 Qi-Qiang Ren Jin-Liang Gao +3 位作者 Rong-Tao Jiang Jin Wang Meng-Ping Li Jian-Wei Feng 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期54-76,共23页
A fault accommodation zone is a type of structure that is defined as regulating displacement and strain between faults structure.Increasing numbers of fault accommodation zones are being identified in graben basins,in... A fault accommodation zone is a type of structure that is defined as regulating displacement and strain between faults structure.Increasing numbers of fault accommodation zones are being identified in graben basins,indicating the potential exploration target and petroleum accumulation areas.This study aims to analyze the formation mechanism and development of fault accommodation zones under combined stress by a numerical simulation method considering geomechanical modeling.Using three-dimensional(3-D)seismic interpretation and fractal dimension method,exampled with the Dongxin fault zone,the fault activity and fault combination pattern were conducted to quantitatively characterize the activity difference in fault accommodation zones.Combined with mechanical experiment test,a geomehcanical model was established for fault accommodation zones in a graben basin.Integrating the paleostress numerical simulations and structural physical simulation experiment,the developmental characteristics and genetic mechanism of fault accommodation zones were summarized.Influenced by multi movements and combined stresses,three significant tectonic evolution stages of the Dongxing Fault Zone(DXFZ)were distinguished:During the E_(s)^(3)sedimentary period,the large difference in the stress,strain,and rupture distribution in various faults were significant,and this stage was the key generation period for the prototype of the DXFZ,including the FAZ between large-scale faults.During the E_(s)^(2)sedimentary period,the EW-trending symmetric with opposite dipping normal faults and the NE-SW trending faults with large scale were furtherly developed.The junction area of two secondary normal faults were prone to be ruptured,performing significant period for inheriting and developing characteristics of fault accommodation zones.During the Es1 sedimentary period,the high-order faults in the DXFZ exhibited the obvious fault depressions and strike-slip activity,and the fault accommodation zones were furtherly inherited and developed.This stage was the molded and formative period of the FAZ,the low-order faults,and the depression in the DXFZ. 展开更多
关键词 Fault accommodation zone Graben basin Fault activity Tectonic physical simulation experiment Finite element numerical simulation Dongxin fault zone
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Kink-band Kinematic Analysis and its Implications for Late-stage Deformation in the Internal Parts of the Zagros Collision(Sanandaj–Sirjan Zone) in West Iran
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作者 Maryam HEYDARI Mahdi BEHYARI 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2024年第4期921-935,共15页
In the internal parts of the Zagros collision zone, several deformation phases have been superimposed. The early deformation phase caused the development of a penetrative foliation. The late-stage deformation phase wa... In the internal parts of the Zagros collision zone, several deformation phases have been superimposed. The early deformation phase caused the development of a penetrative foliation. The late-stage deformation phase was preferentially accommodated within shear zones and caused the generation of shear bands, implying a non-coaxial component of deformation, the end of this stage deformation was marked by the development of kink-bands. In the vicinity of Zagros suture zone, the kink angle increased from 40° to 60°, and the kink-bands was converted to chevron folds. In this region, the external(α) and internal(β) angular ratio is α/β ≠ 1 and kink angle increased, and deformation occurred with 10% to 30% volume loss. Farther from the suture zone in the east, α/β = 1;and total volume was constant or increased by 5% to 10%. Kink-bands kinematic analysis in the study area revealed this structures were sensitive to deformation conditions and components such that, with decreasing distance to the Zagros suture zone, shearing and rotation increased, a high kinematic vorticity dominated, and volume loss occurred during deformation. 展开更多
关键词 kink-band shear zone strain VORTICITY ZAGROS Iran
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