A silver nanoparticle （AgNP） is likely to provide an attractive object for combining a variety of biochemical properties with great therapeutic potential by using radiation. The present study explores the ICs0 value...A silver nanoparticle （AgNP） is likely to provide an attractive object for combining a variety of biochemical properties with great therapeutic potential by using radiation. The present study explores the ICs0 value of chitosan-poly （vinyl alcohol） hydrogel （Cs/PVA） and Ag-doped chitosan-poly （vinyl alcohol） （Cs/PVA/Ag） nanocomposite in view of their anticancer application. The aim was to develop （Cs/PVA） based hydrogel synthesized by gamma radiation which could behave both as a nanoreactor for Ag nanoparticle with promising anticancer applications. The （Cs/PVA/Ag） nanocomposite was confirmed by FTIR （Fourier transform infrared） spectroscopy, XRD （X-ray diffraction） and EDX （energy dispersive X-ray） analysis. The anti-cancer activity of the prepared nanocomposites was demonstrated in human liver cancer cell line （HEPG2） and breast cancer cell lines （MCF7）. It has significant effects against human liver cancer cell line HEPG2 compared to breast cancer cell line MCF7. Further quantitative analysis on the molecular and protein levels is still required to confirm the impact of chitosan on genotoxic effect before reaching a final conclusion and starting its biomedical application.展开更多
The complex tunnelling constructive environment in urban area in similar green field situations is faced through analytical evaluations in order to control the design calculation process and subsequently manage the in...The complex tunnelling constructive environment in urban area in similar green field situations is faced through analytical evaluations in order to control the design calculation process and subsequently manage the interventions techniques with the aim of totally reducing the typical settlements trough above the tunnel either during the construction stage or during the serviceability stage. Recently, the author has proposed an operative and mathematical method by an opportune choice of tensioned anchors to control the tunnel lining settlements. In order to completely eliminate the remainder typical soft soil trough which is normal to the line of the tunnel, it is here proposed to use and properly calculate the interventions of stone columns by the SAVE （silent, advanced, vibration-erasing） Compozer method, in combination with the anchorages.展开更多
AFTER a 32-hour delay, the annual UN climate talks finally came to a close in Lima, Peru, when Peruvian Environment Minister Manuel Pulgar-Vidal struck the gavel in the early hours of December 14, 2014. The 20th sessi...AFTER a 32-hour delay, the annual UN climate talks finally came to a close in Lima, Peru, when Peruvian Environment Minister Manuel Pulgar-Vidal struck the gavel in the early hours of December 14, 2014. The 20th session of the Conference of the Parties to the UN Framework Convention on Climate Change （UNFCCC） saw two-week-long negotiations involving interlocutors from more than 190 countries and organizations. Its conclusion marks a step forward to a new agreement addressing climate change tentatively scheduled to be passed at the end of 2015 in Paris and go into effect in 2020,展开更多
文摘A silver nanoparticle （AgNP） is likely to provide an attractive object for combining a variety of biochemical properties with great therapeutic potential by using radiation. The present study explores the ICs0 value of chitosan-poly （vinyl alcohol） hydrogel （Cs/PVA） and Ag-doped chitosan-poly （vinyl alcohol） （Cs/PVA/Ag） nanocomposite in view of their anticancer application. The aim was to develop （Cs/PVA） based hydrogel synthesized by gamma radiation which could behave both as a nanoreactor for Ag nanoparticle with promising anticancer applications. The （Cs/PVA/Ag） nanocomposite was confirmed by FTIR （Fourier transform infrared） spectroscopy, XRD （X-ray diffraction） and EDX （energy dispersive X-ray） analysis. The anti-cancer activity of the prepared nanocomposites was demonstrated in human liver cancer cell line （HEPG2） and breast cancer cell lines （MCF7）. It has significant effects against human liver cancer cell line HEPG2 compared to breast cancer cell line MCF7. Further quantitative analysis on the molecular and protein levels is still required to confirm the impact of chitosan on genotoxic effect before reaching a final conclusion and starting its biomedical application.
文摘The complex tunnelling constructive environment in urban area in similar green field situations is faced through analytical evaluations in order to control the design calculation process and subsequently manage the interventions techniques with the aim of totally reducing the typical settlements trough above the tunnel either during the construction stage or during the serviceability stage. Recently, the author has proposed an operative and mathematical method by an opportune choice of tensioned anchors to control the tunnel lining settlements. In order to completely eliminate the remainder typical soft soil trough which is normal to the line of the tunnel, it is here proposed to use and properly calculate the interventions of stone columns by the SAVE （silent, advanced, vibration-erasing） Compozer method, in combination with the anchorages.
文摘AFTER a 32-hour delay, the annual UN climate talks finally came to a close in Lima, Peru, when Peruvian Environment Minister Manuel Pulgar-Vidal struck the gavel in the early hours of December 14, 2014. The 20th session of the Conference of the Parties to the UN Framework Convention on Climate Change （UNFCCC） saw two-week-long negotiations involving interlocutors from more than 190 countries and organizations. Its conclusion marks a step forward to a new agreement addressing climate change tentatively scheduled to be passed at the end of 2015 in Paris and go into effect in 2020,
