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融合Mind Map优势助力完善线上线下教学衔接--以园林树木学树种识别教学为例
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作者 刘艺平 贺丹 +1 位作者 李永华 张曼 《高教学刊》 2024年第1期78-81,共4页
疫情当前,线上线下混合式教学已经成为课程教学新模式。树种识别是园林树木学教学的重点和难点,也是教学目的之一。由于课程涉及的树种种类繁多,知识点琐碎,专业术语抽象,再加上课时少任务重,使得教师在教学过程中无法将所有树种的特征... 疫情当前,线上线下混合式教学已经成为课程教学新模式。树种识别是园林树木学教学的重点和难点,也是教学目的之一。由于课程涉及的树种种类繁多,知识点琐碎,专业术语抽象,再加上课时少任务重,使得教师在教学过程中无法将所有树种的特征逐一讲解到,学生在学习过程中也容易混淆,无法有效吸收知识点。因此,在课程的教学改革中,通过引入Mind Map帮助厘清知识框架,优化知识结构,搭建知识关联,不仅使教师授课过程更顺畅,而且能够激发学生在线学习的兴趣,促使学生养成“整理知识点”的良好习惯,使学习效率大幅度提高,从而创建高效的线上课堂,有效巩固混合式教学的教学效果。 展开更多
关键词 线上线下 园林树木学 mind Map 树种识别 混合式教学
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基于Mind+软件的口罩识别与无接触测温装置研究与设计
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作者 苏继恒 冉涛 +2 位作者 王迎辉 白曦龙 宋领赟 《电子设计工程》 2024年第16期1-6,共6页
为了减轻疫情防控中工作人员的负担,降低交叉感染的风险,提高防疫工作效率,设计了一种使用Mind+编程的口罩识别与无接触测温装置。该装置以Arduino作为控制平台,采用HuskyLens模块进行口罩识别,使用非接触式温度传感器MLX90614来测量人... 为了减轻疫情防控中工作人员的负担,降低交叉感染的风险,提高防疫工作效率,设计了一种使用Mind+编程的口罩识别与无接触测温装置。该装置以Arduino作为控制平台,采用HuskyLens模块进行口罩识别,使用非接触式温度传感器MLX90614来测量人体表面温度。该装置经过多次测试,口罩识别准确率为95.83%,温度测量的平均相对误差为0.46%,能够自动检查出未正确佩戴口罩或者体温异常的通行人员,并发出报警信号,禁止其入内。从而有效地减少防疫人员的工作量,降低防疫成本。 展开更多
关键词 ARDUINO 口罩识别 无接触式测温 mind+
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基于Mind+编程软件的“光照条件影响光合作用强度”实验的改进与创新
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作者 钟磊发 张锋 《生物学教学》 北大核心 2024年第7期55-58,共4页
在探究“光照条件”对光合作用强度影响的实验中,对光照强度、光质和光照时间等变量的精准控制是实验成败的关键因素。利用Mind+编程软件,实现256种光照强度的变化;在提高光质纯度的同时,实现70种光质的选择;探究任意频闪频率对光合作... 在探究“光照条件”对光合作用强度影响的实验中,对光照强度、光质和光照时间等变量的精准控制是实验成败的关键因素。利用Mind+编程软件,实现256种光照强度的变化;在提高光质纯度的同时,实现70种光质的选择;探究任意频闪频率对光合作用强度的影响。本实验实现跨学科融合,体现了探究实验的科学性、实用性和创新性。 展开更多
关键词 mind+编程 光照强度 光质 频闪频率 光合作用强度
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Enteric neuropathy in diabetes:Implications for gastrointestinal function
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作者 Mona Mohamed Ibrahim Abdalla 《World Journal of Gastroenterology》 SCIE CAS 2024年第22期2852-2865,共14页
Diabetes,commonly known for its metabolic effects,also critically affects the enteric nervous system(ENS),which is essential in regulating gastrointestinal(GI)motility,secretion,and absorption.The development of diabe... Diabetes,commonly known for its metabolic effects,also critically affects the enteric nervous system(ENS),which is essential in regulating gastrointestinal(GI)motility,secretion,and absorption.The development of diabetes-induced enteric neuropathy can lead to various GI dysfunctions,such as gastroparesis and irregular bowel habits,primarily due to disruptions in the function of neuronal and glial cells within the ENS,as well as oxidative stress and inflammation.This editorial explores the pathophysiological mechanisms underlying the development of enteric neuropathy in diabetic patients.Additionally,it discusses the latest advances in diagnostic approaches,emphasizing the need for early detection and intervention to mitigate GI complications in diabetic individuals.The editorial also reviews current and emerging therapeutic strategies,focusing on pharmacological treatments,dietary management,and potential neuromodulatory interventions.Ultimately,this editorial highlights the necessity of a multidisciplinary approach in managing enteric neuropathy in diabetes,aiming to enhance patient quality of life and address a frequently overlooked complication of this widespread disease. 展开更多
关键词 Diabetic neuropathy GASTROINTESTINAL Insulin resistance DIABETES enteric nervous system enteric neuropathy
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Text Difficulty,Working Memory Capacity and Mind Wandering During Chinese EFL Learners’Reading
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作者 Xianli GAO Li LI 《Chinese Journal of Applied Linguistics》 2024年第3期433-449,525,共18页
This experimental study investigated how text difficulty and different working memory capacity(WMC)affected Chinese EFL learners’reading comprehension and their tendency to engage in task-unrelated thoughts,that is,m... This experimental study investigated how text difficulty and different working memory capacity(WMC)affected Chinese EFL learners’reading comprehension and their tendency to engage in task-unrelated thoughts,that is,mind wandering(MW),in the course of reading.Sixty first-year university non-English majors participated in the study.A two-factor mixed experimental design of 2(text difficulty:difficult and simple)×2(WMC:high/large and low/small)was employed.Results revealed that 1)the main and interaction effects of WMC and text difficulty on voluntary MW were significant,whereas those on involuntary MW were not;2)while reading the easy texts,the involuntary MW of high-WMC individuals was less frequent than that of low-WMC ones,whereas while reading the difficult ones,the direct relationship between WMC and involuntary MW was not found;and that 3)high-WMC individuals had a lower overall rate of MW and better reading performance than low-WMC individuals did,but with increasing text difficulty,their rates of overall MW and voluntary MW were getting higher and higher,and the reading performance was getting lower and lower.These results lend support to WM theory and have pedagogical implications for the instruction of L2 reading. 展开更多
关键词 text difficulty working memory capacity reading mind wandering voluntary mind wandering involuntary mind wandering reading comprehension
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Mindfulness Facets and Psychological Well-Being among Meditators:Serenity as a Mediating Process
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作者 Rebecca Y.M.Cheung Iris Yili Wang Elsa Ngar-Sze Lau 《International Journal of Mental Health Promotion》 2024年第3期177-187,共11页
Guided by the theoretical processes of mindfulness and psychological well-being,this study examined serenity as a mediator between mindfulness facets and psychological well-being,as indexed by depressive symptoms and ... Guided by the theoretical processes of mindfulness and psychological well-being,this study examined serenity as a mediator between mindfulness facets and psychological well-being,as indexed by depressive symptoms and life satisfaction.Participants were 133 mindfulness practitioners who took part in a 3-day transnational meditation event in Hong Kong.Upon informed consent,participants completed a self-report questionnaire.The findings from structural equation modeling showed that serenity mediated the relation between two facets of mindfulness,including describing and nonreacting to inner experience,and life satisfaction.Serenity also mediated the relation between the mindfulness facet of describing and depressive symptoms.Direct associations were indicated between two mindfulness facets,including observing and nonjudging of inner experience,and depressive symptoms.Taken together,the findings revealed mindfulness facets as major correlates of serenity and psychological outcomes among Chinese meditation practitioners.To foster psychological well-being,researchers,educators,and practitioners should pay attention to the role of serenity,describing,and nonreacting to inner experience in mental health. 展开更多
关键词 Depressive symptoms mindFULNESS mindfulness practitioners satisfaction with life SERENITY
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Risk Factors of Enternal Nutrition Intolerance in Septic Patients:A Case-control Study
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作者 Li-zhu WANG Yan XIANG +4 位作者 Qian LI Yi-rong ZHU Jue FANG Xiao-dan LU Zhao-cai ZHANG 《Current Medical Science》 SCIE CAS 2024年第2期328-332,共5页
Objective:This study aimed to investigate the incidence of enteral nutrition intolerance(ENI)in patients with sepsis and explore potential risk factors.Methods:A case-control study was conducted in patients with sepsi... Objective:This study aimed to investigate the incidence of enteral nutrition intolerance(ENI)in patients with sepsis and explore potential risk factors.Methods:A case-control study was conducted in patients with sepsis who were receiving enteral nutrition(EN)at a tertiary hospital in China.The included patients were divided into the ENI group and the non-ENI group.Univariate and multivariate analyses were performed to identify the risk factors for ENI.Results:A total of 859 patients were included in the study.Among them,288(33.53%)patients experienced symptoms of ENI,including diarrhea,vomiting,bloating,and gastric retention.Logistic regression analysis revealed that the Acute Physiology and Chronic Health Evaluation H(APACHE H)score,thoracocentesis,and usage of cardiotonic drugs(namely,inotropes)were independent predictors of the ENI.Conclusion:The incidence of ENI is relatively high in patients with sepsis,especially in those who have higher APACHE H scores,have undergone thoracocentesis,and have received inotropes. 展开更多
关键词 SEPSIS enteral nutrition intolerance influencing factor
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Two intestinal microbiota-derived metabolites, deoxycholic acid and butyrate, synergize to enhance host defense peptide synthesis and alleviate necrotic enteritis
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作者 Dohyung M.Kim Jing Liu +3 位作者 Melanie A.Whitmore Isabel Tobin Zijun Zhao Guolong Zhang 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第3期1158-1172,共15页
Background Necrotic enteritis(NE)is a major enteric disease in poultry,yet effective mitigation strategies remain elusive.Deoxycholic acid(DCA)and butyrate,two major metabolites derived from the intestinal microbiota,... Background Necrotic enteritis(NE)is a major enteric disease in poultry,yet effective mitigation strategies remain elusive.Deoxycholic acid(DCA)and butyrate,two major metabolites derived from the intestinal microbiota,have independently been shown to induce host defense peptide(HDP)synthesis.However,the potential synergy between these two compounds remains unexplored.Methods To investigate the possible synergistic effect between DCA and butyrate in regulating HDP synthesis and barrier function,we treated chicken HD11 macrophage cells and jejunal explants with DCA and sodium butyrate(NaB),either individually or in combination,for 24 h.Subsequently,we performed RNA isolation and reverse transcrip-tion-quantitative PCR to analyze HDP genes as well as the major genes associated with barrier function.To further determine the synergy between DCA and NaB in enhancing NE resistance,we conducted two independent trials with Cobb broiler chicks.In each trial,the diet was supplemented with DCA or NaB on the day-of-hatch,followed by NE induction through sequential challenges with Eimeria maxima and Clostridium perfringens on d 10 and 14,respectively.We recorded animal mortality after infection and assessed intestinal lesions on d 17.The impact of DCA and NaB on the microbiota in the ileum and cecum was evaluated through bacterial 16S rRNA gene sequencing.Results We found that the combination of DCA and NaB synergistically induced multiple HDP genes in both chicken HD11 cells and jejunal explants.Additionally,the gene for claudin-1,a major tight junction protein,also exhibited synergistic induction in response to DCA and NaB.Furthermore,dietary supplementation with a combination of 0.75 g/kg DCA and 1 g/kg NaB led to a significant improvement in animal survival and a reduction in intestinal lesions compared to either compound alone in a chicken model of NE.Notably,the cecal microbiota of NE-infected chickens showed a marked decrease in SCFA-producing bacteria such as Bacteroides,Faecalibacterium,and Cuneatibacter,with lactobacilli becoming the most dominant species.However,supplementation with DCA and NaB largely restored the intestinal microbiota to healthy levels.Conclusions DCA synergizes with NaB to induce HDP and claudin-1 expression and enhance NE resistance,with potential for further development as cost-effective antibiotic alternatives. 展开更多
关键词 Bile acids Host defense peptides METABOLITES MICROBIOME Necrotic enteritis Short-chain fatty acids
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Dietary Macleaya cordata extract supplementation improves the growth performance and gut health of broiler chickens with necrotic enteritis
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作者 Bochen Song Jie He +4 位作者 Xue Pan Linglian Kong Chuanpi Xiao Chake Keerqin Zhigang Song 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第1期374-395,共22页
Background The poultry industry needs effective antibiotic alternatives to control outbreaks of necrotic enteritis(NE)caused by Clostridium perfringens.Methods The aim of this study was to investigate the effects of d... Background The poultry industry needs effective antibiotic alternatives to control outbreaks of necrotic enteritis(NE)caused by Clostridium perfringens.Methods The aim of this study was to investigate the effects of dietary supplementation with Macleaya cordata extract(MCE)on the immune function and gut microbiota of broilers with NE.A total of 2881-day-old broiler chicks were randomly assigned to a 2×2 factorial arrangement with two concentrations of dietary MCE supplementation(0 or 350 mg/kg of diet)and two disease challenge statuses(control or NE).Results The results revealed that NE significantly increased the feed conversion rate(FCR),mortality,intestinal lesion score,the levels of IL-1β,IL-17 and IFN-γ/IL-4 in serum and IL-17/IL-10 in the jejunal mucosa,m RNA levels of TLR2,IFN-γand p Ig R in the jejunum,and Clostridium perfringens concentrations in the cecum.NE significantly decreased the body weight(BW),body weight gain(BWG),jejunal villus height,V/C,m RNA level of AMPK-α1 in jejunum,IL-4 level in the jejunal mucosa and lactic acid bacteria abundance in the cecum.MCE significantly increased BW,BWG,jejunal villus height,V/C,m RNA levels of occludin,ZO-1 and AMPK-α1 in the jejunum,the levels of Ig A and Ig G in serum and IL-10 in the jejunal mucosa and m RNA levels of NF-κB,IL-10 and MHC-II in the jejunum.Additionally,MCE significantly decreased the FCR,mortality,intestinal lesion score,jejunal crypt depth,the levels of IFN-γand IL-17 in serum and IL-17/IL-10 in the jejunal mucosa,Clostridium perfringens concentrations in the cecum,and m RNA levels of IL-17/IL-10 in the jejunum.Moreover,NE significantly increased the abundance of bacteria that are associated with inflammation,obesity and depression(Alistipes,Barnesiella,Intestinimonas,RF39 and UCG-005)and significantly decreased the abundance of short-chain fatty acid(SCFA)-producing bacteria(Anaerotruncus,Butyricicoccus and Bacteroides)in the cecum.MCE significantly increased the abundance of SCFA-producing bacteria(Streptococcus,Ruminococcus_torques_group and Lachnospiraceae_NK4A136_group)and significantly reduced the abundance of bacteria that are associated with inflammation and obesity(Alistipes,Barnesiella and UCG-010)in the cecum.In the cecum of broilers with NE,the relative abundance of Barnesiella and Alistipes was higher and that of Lachnoclostridium and Shuttleworthia was lower.Interestingly,these trends were reversed by the addition of MCE to the diet.Spearman correlation analysis showed that Barnesiella and Alistipes were associated with enhanced intestinal inflammation and inhibited growth performance,whereas Lachnoclostridium and Shuttleworthia were associated with anti-inflammatory effects.Conclusions MCE ameliorated the loss of growth performance in broiler chickens with NE,probably by regulating the intestinal barrier,immune function,and gut microbiota. 展开更多
关键词 Broiler chicken Gut microbiota Immune function Macleaya cordata extract Necrotic enteritis
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Mediating Effect of Mindfulness,Self-Esteem and Psychological Resilience in the Relation between Childhood Maltreatment and Life Satisfaction
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作者 He Zhong Yaping Zhou +1 位作者 Chenwei Liu Yintao Cao 《International Journal of Mental Health Promotion》 2024年第6期481-489,共9页
Childhood maltreatment,as a typical early adverse environment,is known to have a negative impact on one’s life satisfaction.Mindfulness,on the other hand,may serve as a protective factor.This study explored the media... Childhood maltreatment,as a typical early adverse environment,is known to have a negative impact on one’s life satisfaction.Mindfulness,on the other hand,may serve as a protective factor.This study explored the mediating role of mindfulness and its related variables–positive thoughts,psychological resilience and self-esteem.In order to testify the mechanism,we administered Childhood Trauma Questionnaire(CTQ),Satisfaction with Life Scale(SWLS),Mindful Attention Awareness Scale(MAAS),Connor–Davidson Resilience Scale(CD-RISC)and Rosenberg Self-Esteem Scale(RSES)to a non-clinical sample of Chinese university students(N=1021).The results indicated that positive thoughts did not mediate the relationship between childhood maltreatment and life satisfaction,but self-esteem(β=−0.194,95%CI=[−0.090,−0.040])and psychological resilience(β=−0.063,95%CI=[−0.059,−0.020])mediated the relationship,as well as the“mindfulness-selfesteem”(β=−0.061,95%CI=[−0.287,−0.126])and“mindfulness-psychological resilience”(β=−0.035,95%CI=[−0.115,−0.034]).The results of this study were helpful to understand the relationship between childhood maltreatment and life satisfaction and provided a theoretical basis for the development of mindfulness intervention programs from the perspective of positive psychology. 展开更多
关键词 mindFULNESS childhood maltreatment life satisfaction SELF-ESTEEM RESILIENCE
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The Effects of Mindfulness-Based Interventions on Symptoms of Mild Traumatic Brain Injury:A Systematic Review
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作者 Qiqi Feng Zhijian Huang +1 位作者 Yanqiu Wang Bin Wang 《International Journal of Mental Health Promotion》 2024年第6期417-428,共12页
Mindfulness-based interventions(MBIs)are emerging non-pharmacological treatments for mild traumatic brain injury(mTBI).In this systematic review,the authors aimed to evaluate the potential efficacy of MBIs to provide ... Mindfulness-based interventions(MBIs)are emerging non-pharmacological treatments for mild traumatic brain injury(mTBI).In this systematic review,the authors aimed to evaluate the potential efficacy of MBIs to provide recommendations for treating patients with mTBI.We searched of the English literature on MBIs for patients with mTBI as of 01 September,2023,using the PubMed,Web of Science,PsycINFO,and Scopus databases.One author performed data extraction and quality scoring of the included literature according to the proposed protocol,and another conducted the review.The review was not registered.A total of 11 studies met the final inclusion criteria,5 of which involved military personnel(veterans).MBIs covered in this review include goal-oriented attention self-regulation(GOALS),mindfulness-based stress reduction(MBSR),acceptance and commitment therapy(ACT),and so on.Research shows that MBSR mainly reduces mental fatigue symptoms in mTBI patients,and GOALS tend to improve their cognitive function.The effect of MBIs on psychological symptoms needs further exploration.Other studies,such as mindfulness-based group therapy and intervention studies targeting mTBI military personnel,are relatively sparse.MBIs have specific effects on mental fatigue and cognitive dysfunction in patients with mTBI.However,the effect on psychological distress and the sustained effectiveness across all symptoms still need further exploration.Considering the particularity of military personnel suffering from mTBI,researchers need to do more intervention studies targeting mTBI military personnel.Therefore,the design of future MBIs trials for mTBI patients’needs to take into account all the factors,such as different populations and severity of traumatic brain injury,to verify the effectiveness of MBIs in alleviating mTBI symptoms and explore the mechanism of intervention. 展开更多
关键词 mindFULNESS traumatic brain injury MILD
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Porcine enteric alphacoronavirus infection increases lipid droplet accumulation to facilitate the virus replication
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作者 Qi Gao Yongzhi Feng +7 位作者 Ting Gong Dongdong Wu Xiaoyu Zheng Yizhuo Luo Yunlong Yang Zebu Song Lang Gong Guihong Zhang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第3期988-1005,共18页
Coronaviruses are widely transmissible between humans and animals, causing diseases of varying severity. Porcine enteric alphacoronavirus(PEAV) is a newly-discovered pathogenic porcine enteric coronavirus in recent ye... Coronaviruses are widely transmissible between humans and animals, causing diseases of varying severity. Porcine enteric alphacoronavirus(PEAV) is a newly-discovered pathogenic porcine enteric coronavirus in recent years, which causes watery diarrhea in newborn piglets. The host inflammatory responses to PEAV and its metabolic regulation mechanisms remain unclear, and no antiviral studies have been reported. Therefore, we investigated the pathogenic mechanism and antiviral drugs of PEAV. The transcriptomic analysis of PEAV-infected host cells revealed that PEAV could upregulate lipid metabolism pathways. In lipid metabolism, steady-state energy processes, which can be mediated by lipid droplets(LDs), are the main functions of organelles. LDs are also important in viral infection and inflammation. In infected cells, PEAV increased LD accumulation, upregulated NF-κB signaling, promoted the production of the inflammatory cytokines IL-1β and IL-8, and induced cell death. Inhibiting LD accumulation with a DGAT-1 inhibitor significantly inhibited PEAV replication, downregulated the NF-κB signaling pathway, reduced the production of IL-1β and IL-8, and inhibited cell death. The NF-κB signaling pathway inhibitor BAY11-7082 significantly inhibited LD accumulation and PEAV replication. Metformin hydrochloride also exerted anti-PEAV effects and significantly inhibited LD accumulation, downregulated the NF-κB signaling pathway, reduced the production of IL-1β and IL-8, and inhibited cell death. LD accumulation in the lipid metabolism pathway therefore plays an important role in the replication and pathogenesis of PEAV, and metformin hydrochloride inhibits LD accumulation and the inflammatory response to exert anti-PEAV activity and reducing pathological injury. These findings contribute new targets for developing treatments for PEAV infections. 展开更多
关键词 porcine enteric alphacoronavirus NF-κB inflammatory pathway lipid droplet metformin hydrochloride
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Early selective enteral feeding in treatment of acute pancreatitis: A case report
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作者 Aleksei A Kashintsev Sergey V Anisimov +1 位作者 Anastasya Nadeeva Vitali Proutski 《World Journal of Clinical Cases》 SCIE 2024年第3期637-642,共6页
BACKGROUND Early initiation of enteral feeding is recognized to play a crucial role in improving the outcomes of treatment of acute pancreatitis.However,the method of adminis-tration of enteral nutrition remains debat... BACKGROUND Early initiation of enteral feeding is recognized to play a crucial role in improving the outcomes of treatment of acute pancreatitis.However,the method of adminis-tration of enteral nutrition remains debatable.We present the experience of treating a patient with moderate-severe acute pancreatitis,at high risk of progressing to a severe or fatal condition,using a novel method of selective feeding with duodenal isolation.CASE SUMMARY A 27-year-old female patient presented to the emergency unit of the hospital with a typical manifestation of acute pancreatitis.Despite a conventional treatment,the patient’s condition deteriorated by day 2 of hospitalization.Using an endoscopic approach,a novel catheter PandiCathffwas placed to the duodenum of the patient,isolating its segment between the duodenal bulb and the ligament of Treitz.In the isolated area created,a negative pressure was applied,followed by introduction of early selective enteral feeding.The patient’s condition subsequently improved in a rapid manner,and no complications often associated with moderate-to-severe acute pancreatitis developed.CONCLUSION Within 48 h of starting treatment with the novel method,it can prevent the development of multiple organ failure and,when combined with minimally invasive drainage methods,help prevent infection. 展开更多
关键词 Acute pancreatitis enteral feeding Infectious complications Systemic inflammatory response syndrome MODS
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Intestinal microecological transplantation for a patient with chronic radiation enteritis:A case report
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作者 Lin Wang Yan Li +1 位作者 Yu-Jing Zhang Li-Hua Peng 《World Journal of Gastroenterology》 SCIE CAS 2024年第19期2603-2611,共9页
BACKGROUND The gut microbiota is strongly associated with radiation-induced gut damage.This study aimed to assess the effectiveness and safety of intestinal microecological transplantation for treating patients with c... BACKGROUND The gut microbiota is strongly associated with radiation-induced gut damage.This study aimed to assess the effectiveness and safety of intestinal microecological transplantation for treating patients with chronic radiation enteritis.CASE SUMMARY A 64-year-old female with cervical cancer developed abdominal pain,diarrhea,and blood in the stool 1 year after radiotherapy.An electronic colonoscopy was performed to diagnose chronic radiation enteritis.Two courses of intestinal microecological transplantation and full-length 16S rRNA microbiological analysis were performed.The patient experienced short-and long-term relief from symptoms without adverse effects.Whole 16S rRNA sequencing revealed significant differences in the intestinal flora’s composition between patient and healthy donors.Pathogenic bacteria,such as Escherichia fergusonii and Romboutsia timonensis,were more in the patient.Beneficial bacteria such as Faecalibacterium prausnitzii,Fusicatenibacter saccharivorans,Ruminococcus bromii,and Bifidobacterium longum were more in the healthy donors.Intestinal microbiota transplantation resulted in a significant change in the patient's intestinal flora composition.The composition converged with the donor's flora,with an increase in core beneficial intestinal bacteria,such as Eubacterium rectale,and a decrease in pathogenic bacteria.Changes in the intestinal flora corresponded with the patients'alleviating clinical symptoms.CONCLUSION Intestinal microecological transplantation is an effective treatment for relieving the clinical symptoms of chronic radiation enteritis by altering the composition of the intestinal flora.This study provides a new approach for treating patients with chronic radiation enteritis. 展开更多
关键词 Chronic radiation enteritis Gut microbial transplantation Intestinal microecology Cancer Quality of life Case report
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Mindfulness training in medical education as a means to improve resilience,empathy,and mental health in the medical profession
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作者 Edison Iglesias de Oliveira Vidal Luiz Fernando Alvarenga Ribeiro +1 位作者 Marco Antonio de Carvalho-Filho Fernanda Bono Fukushima 《World Journal of Psychiatry》 SCIE 2024年第4期489-493,共5页
The high rates of depression,burnout,and increased risk of suicide among medical students,residents,and physicians in comparison with other careers signal a mental health crisis within our profession.We contend that t... The high rates of depression,burnout,and increased risk of suicide among medical students,residents,and physicians in comparison with other careers signal a mental health crisis within our profession.We contend that this crisis coupled with the inadequate acquisition of interpersonal skills during medical education results from the interaction between a challenging environment and the mental capital of individuals.Additionally,we posit that mindfulness-based practices are instrumental for the development of major components of mental capital,such as resilience,flexibility of mind,and learning skills,while also serving as a pathway to enhance empathy,compassion,self-awareness,conflict resolution,and relational abilities.Importantly,the evidence base supporting the effectiveness of mindfulness-based interventions has been increasing over the years,and a growing number of medical schools have already integrated mindfulness into their curricula.While we acknowledge that mindfulness is not a panacea for all educational and mental health problems in this field,we argue that there is currently an unprecedented opportunity to gather momentum,spread and study mindfulness-based programs in medical schools around the world as a way to address some longstanding shortcomings of the medical profession and the health and educational systems upon which it is rooted. 展开更多
关键词 mindFULNESS Medical education Mental capital Mental health Medical students RESILIENCE
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Potential pharmacological mechanisms of digallate in the treatment of enteritis based on network pharmacology and molecular docking
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作者 Ning Tang Lian-Dong Zhao +3 位作者 Yang Zhao Yu-Meng Han Yue Cao Yan Wang 《Integrative Medicine Discovery》 2024年第7期1-10,共10页
Background:In order to investigate the possible pharmacological mechanism of digallate in Galla Chinensis for treating enteritis,providing reference for the search and exploration of effective drugs for treating enter... Background:In order to investigate the possible pharmacological mechanism of digallate in Galla Chinensis for treating enteritis,providing reference for the search and exploration of effective drugs for treating enteritis.Method:Traditional Chinese Medicines Systems Pharmacology Database and Analysis Platform,PharmMapper,DisGeNET,DrugBank,and GeneCards databases were used to obtain drug and disease-related target information.Gene ontology functional annotation and Kyoto Encyclopedia of Genes and Genomes pathway enrichment were performed,and the main therapeutic pathways and targets were identified by combining protein-protein interaction networks and cytoHubba plug-in.Molecular docking was used to validate the results.Result:297 drug related targets,2436 disease related targets,and 66 target points related to digallate were predicted to be associated with enteritis.10 related signal pathways and 10 key genes were identified.Conclusion:Digallate may be utilized to treat enteritis by acting on similar pathways,such those related to pathways in cancer,lipid and atherosclerosis,proteoglycans in cancer,Rap1 signaling pathway,PI3K-Akt signaling pathway and other targets such as IGF1,EGFR,SRC,IGF1R,PPARG. 展开更多
关键词 digallate enterITIS network pharmacology molecular docking
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Cognitive dissonance and mindset perturbations during crisis:“ecosocio-psycho-somatic”perspectives
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作者 Felix Tretter Henriette Löffler-Stastka 《World Journal of Psychiatry》 SCIE 2024年第2期215-224,共10页
Mandatory and restrictive health regulations during the corona pandemic caused psychic disorders in many people,which even led to clinically relevant mental disorders.At the same time,there was gradually a polarizatio... Mandatory and restrictive health regulations during the corona pandemic caused psychic disorders in many people,which even led to clinically relevant mental disorders.At the same time,there was gradually a polarization of opinions among the population.In order to improve future pandemic management,an integrative understanding of these psychosocial processes therefore seems useful.Here we start theoretically with the mental effects of inconsistencies of the information environment by referring to concepts such as the theory of cognitive dissonance.In a next step,we use the psychodynamic theory to understand the affective-motivational defense mechanisms underlying these cognitive states and processes.However,a broader theoretical framework of psychoanalysis seems to make sense,because self-referential processing also influences the style of thinking.For this reason,we use a more comprehensive psychological systems theoretical framework model to integrate these different perspectives.This integrative view refers in part to basic knowledge of health psychology regarding the resistance of unhealthy ways of thinking and behaviors and the possibilities for interventions for change.We then extend this model to a broader picture that also covers the relationship between men and their environment.This results in the perspective of a multidimensional socioecological theoretical framework,which as a heuristic reference model and related to other ecological approaches could also be helpful for various theoretical questions for public health,and could provide a better public understanding of health issues.In line with this perspective,we hypothesize that with regard to the coronavirus disease 2019 pandemic,the acceptance of public health narratives could be increased if a more consistent picture of the scientific descriptions and explanations of the pandemic-similar to the model proposed-could be provided,which would enable the understanding of the origin,course and countermeasures,and thus could have positive collective psycho-hygienic effects. 展开更多
关键词 Infodemic Affective-cognitive dissonance Systems model of the mind Socioecological model
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Phytochemical screening and antibacterial activities of Momordica charantia and Vernonia amygdalina extracts on some selected enteric isolates
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作者 Seyi-Samson Enitan Zaynab-Aderonke Ojubanire +4 位作者 Temiloluwa-Femi Oyedele Nwachi-Idume Ogbonna Adekunle-Totoola Adeyemi Jamiu-Monsur Olalekan Ayomide-Oluwatobiloba Okuneye 《TMR Modern Herbal Medicine》 CAS 2024年第1期11-18,共8页
Background:This research focuses on herbal medicine,an ancient healthcare practice,exploring the antibacterial attributes of fresh and dried leaf extracts from Momordica charantia(commonly known as Bitter melon)and Ve... Background:This research focuses on herbal medicine,an ancient healthcare practice,exploring the antibacterial attributes of fresh and dried leaf extracts from Momordica charantia(commonly known as Bitter melon)and Vernonia amygdalina(Bitter leaf).The study specifically investigates their effects on different bacterial strains associated with gastroenteritis.Methods:Four enteric bacterial isolates-Klebsiella pneumoniae,Salmonella typhi,Escherichia coli,and Proteus mirabilis-were obtained from the Medical Laboratory Unit at Babcock University Teaching Hospital in Ilishan-Remo,Ogun State.Phytochemical screening and antibacterial testing were conducted using standard biochemical techniques and the Punch-hole agar diffusion method,respectively.Results:Qualitative phytochemical screening of the plant extracts revealed the presence of flavonoids,glycosides,and saponin in both plants,excluding terpenoids.Alkaloids were identified only in Vernonia amygdalina.Despite these phytochemicals,neither plant displayed inhibitory effects on the tested bacterial isolates(Escherichia coli,Proteus mirabilis,Klebsiella pneumoniae,and Salmonella typhi)when tested individually or in combination.Intriguingly,combining the fresh and dried leaf extracts of Momordica charantia and Vernonia amygdalina with a standard drug resulted in smaller mean zone diameters of inhibition(Escherichia coli range:14 mm–16 mm,Proteus mirabilis range:31 mm–35 mm,Klebsiella pneumoniae range:13 mm–22 mm,and Salmonella typhi range:35 mm–38 mm)compared to the drug tested alone(16 mm–45 mm).Conclusion:Despite previous indications of antibacterial properties in various extracts of V.amygdalina and M.charantia leaves,our study presents contradictory results,prompting the need for further investigation despite the presence of significant phytochemicals. 展开更多
关键词 phytochemical screening herbal medicine Momordica charantia Vernonia amygdalina enteric isolates
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Mind+与培智班会课融合的教学探究——以《我的中国梦》为例
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作者 谢凤怡 《教育信息技术》 2024年第1期69-71,共3页
新时代背景下,特殊教育德育工作面临着新的机遇和挑战。由于学生的特殊性,培智课堂班会课的组织形式应更加丰富。文章从培智学生德育的角度出发,将班会课堂与Mind+编程软件融合,旨在提升学生在信息建立、能力培养、个性发展以及社会交... 新时代背景下,特殊教育德育工作面临着新的机遇和挑战。由于学生的特殊性,培智课堂班会课的组织形式应更加丰富。文章从培智学生德育的角度出发,将班会课堂与Mind+编程软件融合,旨在提升学生在信息建立、能力培养、个性发展以及社会交往方面的能力。运用操作简单、界面丰富的Mind+编程软件创新教学形式,融入班会课堂,以主题“我的中国梦”为例,开展教学实践,让学生在快乐的编程活动中,内化班会课主题的情感体验。最后探讨Mind+与班会课融合后产生的教学效果,打造高效班会课堂,为培智学校开展班会课提供参考。 展开更多
关键词 mind+ 班会课 培智
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Mind+结合XEduHub开发AI交互作品
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作者 谢作如 邱奕盛 《中国信息技术教育》 2024年第11期88-90,共3页
在图形化编程工具Mind+和通用AI推理库XEdu Hub的支持下,中小学生使用简短的代码就能设计出有趣的AI交互作品。本文在介绍Mind+和XEdu Hub的同时,分析了AI交互作品的核心环节,指出作品可以由感知输入、智能处理和执行呈现三个部分组成,... 在图形化编程工具Mind+和通用AI推理库XEdu Hub的支持下,中小学生使用简短的代码就能设计出有趣的AI交互作品。本文在介绍Mind+和XEdu Hub的同时,分析了AI交互作品的核心环节,指出作品可以由感知输入、智能处理和执行呈现三个部分组成,希望为中小学开展AI教育提供新的思路。 展开更多
关键词 mind+ XEdu Hub AI交互作品
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