以“草果”“菌”“病毒”“化学成分”“作用机制”“Amomum tsao-ko”“Antibacterial”“Antimicrobial”“Virus”“Chemical composition”“Mechanism”等为关键词,在中国知网、维普数据库、中国专利网、PubMed、Web of Science...以“草果”“菌”“病毒”“化学成分”“作用机制”“Amomum tsao-ko”“Antibacterial”“Antimicrobial”“Virus”“Chemical composition”“Mechanism”等为关键词,在中国知网、维普数据库、中国专利网、PubMed、Web of Science等数据库中组合查询到2011~2023年中的有效文献57篇,对草果抗菌物质基础、抗菌活性与机理、抗病毒活性等方面进行归纳与总结。表明草果具有广谱的抗微生物活性,对细菌、真菌和HSV-1病毒均具有不同程度的体外抑制作用和体内抗感染作用,其中挥发油、酚酸、黄酮及双环壬烷类为草果抗菌物质基础,作用机制主要表现为破坏细胞壁、细胞膜的完整性及抑制病原菌的呼吸代谢过程。但目前对草果抗微生物作用多局限于粗提物的体外抑制,体内各个药物组分之间的相互作用并不明确,且缺乏毒理学和药动学的相关研究,其安全性及药效物质基础尚需进一步深入探索。展开更多
The study area is located in Kawakami-cho, Okayama Prefecture,which is occupied by Lower Carboniferous to Middle Permian Ko-yama Limestone Group(Yokoyama et al.,1979),Permian Yoshii Group (Sano et al.,1987) and Triass...The study area is located in Kawakami-cho, Okayama Prefecture,which is occupied by Lower Carboniferous to Middle Permian Ko-yama Limestone Group(Yokoyama et al.,1979),Permian Yoshii Group (Sano et al.,1987) and Triassic Nariwa展开更多
The Carboniferous conodont faunal succession of the lower part of Ko-yama Limestone Group was studied.The confirmed upper Visean-lower Moscovian lithostratigraphy of the group is characterized by the clastic carbonate...The Carboniferous conodont faunal succession of the lower part of Ko-yama Limestone Group was studied.The confirmed upper Visean-lower Moscovian lithostratigraphy of the group is characterized by the clastic carbonates with common association of the basaltic pyroclastics and some intercalation of spicular chert beds.The faunal succession of Gnathodus semiglaber(upper Visean),Gnathodus praebilineatus-Lochriea multinodosa(upper Visean),Lochriea ziegleri-Gnathodus girtyi girtyi s.l.(lower Serpukhovian),Neoganthodus symmetricus-Idiognathodus primulus(middle-upper Bashkirian),and Idiognathoides convexus-Gondolella clarki(lower Moscovian) faunas,appears in concordance with the lithostratigraphic order.The faunas are correlative with those from the conodont zones of the Hina,Atetsu,Akiyoshi and Omi limestone groups in the Akiyoshi Belt.The Visean/Serpukhovian boundary of the section was recognized by the FAD of Lochriea ziegleri.展开更多
文摘以“草果”“菌”“病毒”“化学成分”“作用机制”“Amomum tsao-ko”“Antibacterial”“Antimicrobial”“Virus”“Chemical composition”“Mechanism”等为关键词,在中国知网、维普数据库、中国专利网、PubMed、Web of Science等数据库中组合查询到2011~2023年中的有效文献57篇,对草果抗菌物质基础、抗菌活性与机理、抗病毒活性等方面进行归纳与总结。表明草果具有广谱的抗微生物活性,对细菌、真菌和HSV-1病毒均具有不同程度的体外抑制作用和体内抗感染作用,其中挥发油、酚酸、黄酮及双环壬烷类为草果抗菌物质基础,作用机制主要表现为破坏细胞壁、细胞膜的完整性及抑制病原菌的呼吸代谢过程。但目前对草果抗微生物作用多局限于粗提物的体外抑制,体内各个药物组分之间的相互作用并不明确,且缺乏毒理学和药动学的相关研究,其安全性及药效物质基础尚需进一步深入探索。
文摘The study area is located in Kawakami-cho, Okayama Prefecture,which is occupied by Lower Carboniferous to Middle Permian Ko-yama Limestone Group(Yokoyama et al.,1979),Permian Yoshii Group (Sano et al.,1987) and Triassic Nariwa
文摘The Carboniferous conodont faunal succession of the lower part of Ko-yama Limestone Group was studied.The confirmed upper Visean-lower Moscovian lithostratigraphy of the group is characterized by the clastic carbonates with common association of the basaltic pyroclastics and some intercalation of spicular chert beds.The faunal succession of Gnathodus semiglaber(upper Visean),Gnathodus praebilineatus-Lochriea multinodosa(upper Visean),Lochriea ziegleri-Gnathodus girtyi girtyi s.l.(lower Serpukhovian),Neoganthodus symmetricus-Idiognathodus primulus(middle-upper Bashkirian),and Idiognathoides convexus-Gondolella clarki(lower Moscovian) faunas,appears in concordance with the lithostratigraphic order.The faunas are correlative with those from the conodont zones of the Hina,Atetsu,Akiyoshi and Omi limestone groups in the Akiyoshi Belt.The Visean/Serpukhovian boundary of the section was recognized by the FAD of Lochriea ziegleri.
