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Bilateral carpal tunnel syndrome and motor dysfunction caused by gout and type 2 diabetes:A case report
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作者 Gao-Feng Zhang Cun-Min Rong +3 位作者 Wei Li Ben-Lei Wei Ming-Tong Han Qing-Luan Han 《World Journal of Clinical Cases》 SCIE 2023年第11期2535-2540,共6页
BACKGROUND Carpal tunnel syndrome(CTS)has been associated with gout and type 2 diabetes mellitus(T2DM).However,due to insufficient clinical understanding of goutrelated CTS and reliance on the diagnostic importance of... BACKGROUND Carpal tunnel syndrome(CTS)has been associated with gout and type 2 diabetes mellitus(T2DM).However,due to insufficient clinical understanding of goutrelated CTS and reliance on the diagnostic importance of elevated serum uric acid levels,such cases are prone to missed diagnosis,misdiagnosis,and delayed treatment.In addition,the effect of T2DM on gout-induced carpal tunnel syndrome has not been reported.CASE SUMMARY Herein,we present an unusual case of CTS and motor dysfunction caused by miliary tophaceous gout and T2DM.The patient presented to the hand and foot clinic with paresthesia of the fingers of both hands,especially at night.The patient was diagnosed with type 2 diabetes a month ago.Ultrasonography revealed bilateral transverse carpal ligament thickening with median nerve compression during hospitalization.The patient was successfully treated with carpal tunnel decompression and tendon release.The postoperative pathological examination revealed typical gout nodules.This case suggests that the presence of T2DM could accelerate tophi formation and worsen CTS symptoms,although no definitive proof in this regard has been described previously.CONCLUSION Tophi formation may most likely cause the co-occurrence of CTS and flexor dysfunction in gout and incipient diabetes patients. 展开更多
关键词 Carpal tunnel syndrome motor dysfunction Tophaceous gout type 2 diabetes mellitus Operate Case report
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THE EQUIVALENT CIRCUIT AND CONTROL SYSTEM OF TRAVELLING WAVE TYPE ULTRASONIC MOTOR
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作者 夏长亮 史婷娜 +1 位作者 薛向党 刘承榆 《Transactions of Tianjin University》 EI CAS 1997年第2期23-27,共5页
从压电振子的等效电路出发,得到了行波型超声波电动机定子环乃至整个电动机的等效电路.分别对电机控制系统各组成部分进行了分析,并利用电机等效电路达到简化控制系统的目的.实验对研究结果进行了验证.
关键词 行波型 超声波电动机 等效电路 控制系统
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NT-proBNP对有创机械通气小儿急性呼吸衰竭28 d内死亡的预测价值研究
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作者 陈秀萍 李斯婕 +3 位作者 梁秀安 赵云柳 伍冬梅 林源 《广西医科大学学报》 CAS 2024年第4期579-584,共6页
目的:研究氧合指数(OI)和N末端B型钠尿肽前体(NT-proBNP)在儿童重症监护病房(PICU)需要有创机械通气的急性呼吸衰竭(ARF)患儿28 d内死亡的预测价值。方法:选取2017—2019年入住本院PICU的需要有创机械通气的111例ARF患儿,收集并分析患... 目的:研究氧合指数(OI)和N末端B型钠尿肽前体(NT-proBNP)在儿童重症监护病房(PICU)需要有创机械通气的急性呼吸衰竭(ARF)患儿28 d内死亡的预测价值。方法:选取2017—2019年入住本院PICU的需要有创机械通气的111例ARF患儿,收集并分析患儿临床资料,包括儿童机械通气死亡风险评分Ⅲ(PRISMⅢ)、OI、NT-proBNP、机械通气后28 d内生存情况等。采用单因素和多因素logistic回归分析评估ARF患儿28 d内死亡的危险因素。采用受试者工作特征(ROC)曲线评估NT-proBNP、OI和年龄预测28 d生存情况的效果。结果:患儿中位年龄12个月(4.5~66个月),28 d内79例存活(71.17%),32例死亡(28.83%)。与存活组相比,死亡组OI显著升高,NT-proBNP水平显著降低(均P<0.05),两组24 h内PRISMⅢ评分无显著差异(P>0.05)。多因素logistic回归分析结果显示,年龄、OI、NT-proBNP均为ARF患儿28 d内死亡的独立危险因素(P<0.05)。年龄、OI、NT-proBNP及三者联合的ROC曲线下面积(AUC)分别为0.625 0、0.603 6、0.602 8和0.657 2,年龄+OI+NT-proBNP联合具有更好的预测效果。结论:在ARF需机械通气患儿中,最初24 h的年龄、OI和NT-proBNP水平与28 d死亡风险相关;年龄、OI和NT-proBNP三者联合有助于早期识别ARF插管患儿死亡风险。 展开更多
关键词 氧合指数 n末端B型钠尿肽前体 死亡风险 儿童重症监护病房 呼吸衰竭
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从“数量名+NP”话题句看话题和述题的复杂依存关系
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作者 宋文辉 《汉语学习》 北大核心 2024年第2期3-9,共7页
汉语“数量名+NP”在特定语境中可作话题,被赋予定指理解,但同时也凸显数量特征,是有标记话题。该结构要求述题须表达数量特征,但受句子体特征和语用因素影响其内部也有细微差别。“数量名”话题自身的特征与“话题—述题”的陈述关系... 汉语“数量名+NP”在特定语境中可作话题,被赋予定指理解,但同时也凸显数量特征,是有标记话题。该结构要求述题须表达数量特征,但受句子体特征和语用因素影响其内部也有细微差别。“数量名”话题自身的特征与“话题—述题”的陈述关系决定结构对述题的要求,而述题的构造和语义也有助于话题指称类型的理解,二者相互依存。 展开更多
关键词 “数量名”nP 指称类型 话题 述题 零形回指
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H-FABP、NT-proBNP与急性心力衰竭患者容量负荷状态及预后的相关性
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作者 张晓丽 张海柱 +2 位作者 可海霞 王永革 魏华 《河南医学研究》 CAS 2024年第10期1834-1837,共4页
目的 研究心型脂肪酸结合蛋白(H-FABP)、氨基端脑钠肽前体(NT-proBNP)对急性心力衰竭患者容量负荷状态及预后的评估。方法 本研究为前瞻性研究,以2021年1月至2022年1月于安阳市人民医院急诊住院的老年急性心力衰竭患者83例作为研究组,... 目的 研究心型脂肪酸结合蛋白(H-FABP)、氨基端脑钠肽前体(NT-proBNP)对急性心力衰竭患者容量负荷状态及预后的评估。方法 本研究为前瞻性研究,以2021年1月至2022年1月于安阳市人民医院急诊住院的老年急性心力衰竭患者83例作为研究组,另选取83例健康者作为对照组。根据相对容量平衡水平,将以上83例患者分为容量超负荷组和非容量超负荷组,对所有出院患者随访3个月,将发生死亡的患者归为死亡组,其余为生存组。比较研究组与对照组不同容量负荷、不同预后的H-FABP、NT-proBNP水平之间的差异,研究H-FABP、NT-proBNP与生存状况以及容量负荷状态的相关性。结果 研究组患者的H-FABP、NT-proBNP水平高于对照组(P<0.001);容量超负荷组患者的H-FABP、NT-proBNP水平高于非容量超负荷组(P<0.05);死亡组患者的H-FABP、NT-proBNP水平高于生存组(P<0.05)。通过相关性分析,患者的死亡以及容量超负荷与H-FABP、NT-proBNP呈现正相关(P<0.001)。结论 H-FABP、NT-proBNP与急性心力衰竭患者容量负荷状态及预后呈现相关性,有助于评估急性心力衰竭的严重程度,对预后不良患者起到积极的指导治疗作用。 展开更多
关键词 心型脂肪酸结合蛋白 容量负荷状态 急性心力衰竭 预后 氨基端脑钠肽前体
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CTRP3联合NT-proBNP对MVD患者发生HHcy的预测价值
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作者 李欣 张明亮 +2 位作者 曲超 邢丽婷 王嵬民 《中国实用医药》 2024年第3期68-71,共4页
目的探讨补体C1q/肿瘤坏死因子相关蛋白3(CTRP3)联合N末端B型利钠肽前体(NT-proBNP)对冠状动脉(冠脉)多支病变(MVD)患者发生高同型半胱氨酸血症(HHcy)的预测价值。方法回顾性分析200例MVD患者的临床资料,根据血浆同型半胱氨酸(Hcy)水平... 目的探讨补体C1q/肿瘤坏死因子相关蛋白3(CTRP3)联合N末端B型利钠肽前体(NT-proBNP)对冠状动脉(冠脉)多支病变(MVD)患者发生高同型半胱氨酸血症(HHcy)的预测价值。方法回顾性分析200例MVD患者的临床资料,根据血浆同型半胱氨酸(Hcy)水平是否>15μmol/L分为高Hcy组(111例)和正常Hcy组(89例)。比较两组基线资料[年龄、性别、冠心病病程、吸烟史、糖尿病病史、高血压病史、体质量指数(BMI)],生化指标(NT-proBNP、尿酸(UA)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、Hcy、CTRP3),采用二元Logistic回归分析法分析影响MVD患者发生HHcy危险因素,绘制受试者工作特征(ROC)曲线分析CTRP3联合NT-proBNP对MVD患者发生HHcy的预测效能。结果两组年龄、高血压病史、BMI、UA、TG、TC、HDL-C比较均无统计学差异(P>0.05);高Hcy组男性患者数量70例、冠心病病程(6.66±4.49)年、吸烟史55例、糖尿病病史60例,均大于正常Hcy组的36例、(3.67±2.31)年、28例、17例,NT-proBNP(5234.95±7476.76)pg/ml、LDL-C(3.55±0.95)mmol/L、Hcy(44.75±12.48)μmol/L均高于正常Hcy组的(1296.94±3864.78)pg/ml、(2.95±0.88)mmol/L、(10.58±2.80)μmol/L,CTRP3(65.20±13.61)μg/L低于正常Hcy组的(88.69±14.94)μg/L,两组间比较差异均具有统计学意义(P<0.05)。多因素Logistic回归分析显示:男性[OR=3.745,95%CI=(1.398,10.030)]、糖尿病病史[OR=3.262,95%CI=(1.264,8.417)]、冠心病病程[OR=1.194,95%CI=(1.022,1.394)]、LDL-C[OR=2.254,95%CI=(1.337,3.800)]为导致MVD患者发生HHcy的独立危险因素,而CTRP3[OR=0.902,95%CI=(0.873,0.933)]为其独立保护因素(P<0.05)。ROC曲线结果显示:CTRP3联合NT-proBNP预测MVD患者发生HHcy的AUC为0.901,敏感度为83.8%,特异度为86.5%,优于LDL-C、NT-proBNP或CTRP3单独预测(P<0.05)。结论性别、糖尿病病史、冠心病病程、LDL-C为导致MVD患者发生HHcy的独立危险因素,而CTRP3为其独立保护因素。血清CTRP3联合NT-proBNP可提高MVD患者发生HHcy的预测价值。 展开更多
关键词 冠状动脉多支病变 高同型半胱氨酸血症 n末端B型利钠肽前体 补体C1q/肿瘤坏死因子相关蛋白3 预测价值
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急性阵发性房颤患者基线NT-proBNP对胺碘酮复律疗效的影响
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作者 邓水清 黄小辉 《中国卫生标准管理》 2024年第10期142-145,共4页
目的 探讨N末端B型利钠肽原(N-terminal pro B-type natriuretic peptide,NT-proBNP)在胺碘酮用于急性阵发性房颤(acute atrial fibrillation,AF)复律疗效评估中的价值。方法纳入2019年2月—2022年7月三明市第二医院急诊科明确诊断为AF... 目的 探讨N末端B型利钠肽原(N-terminal pro B-type natriuretic peptide,NT-proBNP)在胺碘酮用于急性阵发性房颤(acute atrial fibrillation,AF)复律疗效评估中的价值。方法纳入2019年2月—2022年7月三明市第二医院急诊科明确诊断为AF(非瓣膜病)的68例患者,所有患者排除禁忌后均给予胺碘酮复律治疗,根据复律后转复情况分为2组,即成功转复组(n=57)与转复失败组(n=11)。对比2组症状与体征(心悸、胸痛)、心电图表现(是否合并ST段压低)、既往病史(是否合并糖尿病、高血压病、冠心病等)、房颤持续时间和基线NT-proBNP水平。采用二元logistic回归分析AF患者胺碘酮复律疗效的影响因素。结果 2组胸痛、合并糖尿病、合并冠心病、ST段压低、房颤持续时间、合并高血压比较,差异无统计学意义(P>0.05)。成功转复组心悸发生率为28.07%、NT-proBNP水平为(229.43±7.24)pmol/L,优于转复失败组的63.64%、(679.99±8.67)pmol/L,差异有统计学意义(P<0.05)。入院时存在心悸症状、NT-proBNP是影响AF患者应用胺碘酮转复的主要因素(P<0.05)。结论 胺碘酮对AF(非瓣膜病)患者复律治疗安全有效,入院时存在心悸症状、基线NT-proBNP水平是预测胺碘酮复律成功的重要因素。 展开更多
关键词 n末端B型利钠肽原 胺碘酮 房颤 复律 非瓣膜病 评估价值
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鹅颈藤壶多糖提取、理化性质及N-糖链表达谱分析研究
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作者 王茹 姜媛媛 +5 位作者 林川 潘琳 管守德 于广利 吕友晶 李国云 《中国海洋大学学报(自然科学版)》 CAS CSCD 北大核心 2024年第1期95-103,共9页
本文以南海海域鹅颈藤壶(Lepas anatifera)为原料,提取鹅颈藤壶背甲与肌肉质柄中的多糖,基于其基本理化性质的分析,比较不同生长时期鹅颈藤壶N-糖链表达谱的差异性。经过脱脂、碱水解/蛋白酶解、乙醇沉淀方法提取得到粗多糖;利用高效液... 本文以南海海域鹅颈藤壶(Lepas anatifera)为原料,提取鹅颈藤壶背甲与肌肉质柄中的多糖,基于其基本理化性质的分析,比较不同生长时期鹅颈藤壶N-糖链表达谱的差异性。经过脱脂、碱水解/蛋白酶解、乙醇沉淀方法提取得到粗多糖;利用高效液相色谱法、高效凝胶渗透色谱法、苯酚-硫酸法、考马斯亮蓝法对其单糖组成、分子量分布、总糖含量及蛋白质含量进行分析;采用液质分析(PGC-ESI-MS/MS)方法对鹅颈藤壶成体(A-GB)与幼体(L-GB)肌肉质柄中N-糖链进行分析并比较。表明肌肉质柄中多糖分子量为18.40 kDa;总糖含量为11.99%,蛋白质含量60.14%,富含甘露糖、葡萄糖、氨基半乳糖,其中甘露糖的含量高达80%以上。在鹅颈藤壶成体与幼体中均鉴定得到26条N-糖链,成体中高甘露糖型N-糖链占总糖链的20.81%,且相对丰度较高的糖型组成为F_(1)H_(3)N_(2)(39.06%)、F_(1)H_(3)N_(3)(24.44%)、H_(3)N_(3)(9.35%);幼体中高甘露糖型N-糖链占总糖链的52.17%,相对丰度较高的糖型组成为F_(1)H_(3)N_(2)(21.65%)、H_(6)N_(2)(15.93%)、H_(5)N_(2)(14.75%)。鹅颈藤壶多糖是一类N-糖基化的蛋白复合物,推测N-糖链在鹅颈藤壶长发育过程中发挥着至关重要的作用,可能高甘露糖型N-糖链与其附着黏附能力密切相关。 展开更多
关键词 鹅颈藤壶多糖 n-糖链 高甘露糖型 表达谱究
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Visualization and Quantitative Evaluation of Eddy Current Loss in Bar-Wound Type Permanent Magnet Synchronous Motor for Mild-Hybrid Vehicles 被引量:2
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作者 Masahiro Aoyama Jianing Deng 《CES Transactions on Electrical Machines and Systems》 CSCD 2019年第3期269-278,共10页
This paper describes the conductor eddy current loss that occurs in a permanent magnet type synchronous motor with a distributed winding stator using a rectangular copper wire designed for mild hybrid system applicati... This paper describes the conductor eddy current loss that occurs in a permanent magnet type synchronous motor with a distributed winding stator using a rectangular copper wire designed for mild hybrid system applications for small vehicles.Compared with the conventional round wire inserter method,the space factor can be improved and the coil-end length can be shortened by applying a so-called hairpin windings using a pre-formed into hairpin shape of bar conductor,and as a result,DC current resistance of the armature winding can be reduced.However,since the conductor cross-sectional area tends to increases,the conductor eddy current loss generated by the space harmonics linkage becomes too large to ignore.In order to study the reduction of the conductor eddy current loss,it is important to visualize the spatial leakage flux distribution which causes loss and finely analyze how the magnetic path is formed.Therefore,analysis of the conductor eddy current loss distribution generated in the bar-wound conductor is performed using the CAE model that faithfully reproduces the coil-end shape of the actual machine.Furthermore,it was qualitatively clarified what ratio of conductor eddy current loss at various driving points.Finally,the results of preliminary study on reduction of conductor eddy current loss are reported. 展开更多
关键词 Conductor eddy current loss hairpin windings type permanent magnet synchronous motor leakage magnetic flux.
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CYP2C19基因多态性、血清NT-proBNP水平与急性脑梗死静脉溶栓预后不良的关系
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作者 钱倩 张静 +2 位作者 张欣 邢晓明 边伟林 《山东医药》 CAS 2024年第4期13-17,共5页
目的探讨CYP2C19基因多态性、血清N末端B型脑利钠肽前体(NT-proBNP)水平与急性脑梗死(ACI)患者静脉溶栓预后不良的关系。方法选择210例ACI患者,均行阿替普酶静脉溶栓治疗,治疗90 d后根据改良Rankin量表(mRS)评分将患者分为预后不良组(mR... 目的探讨CYP2C19基因多态性、血清N末端B型脑利钠肽前体(NT-proBNP)水平与急性脑梗死(ACI)患者静脉溶栓预后不良的关系。方法选择210例ACI患者,均行阿替普酶静脉溶栓治疗,治疗90 d后根据改良Rankin量表(mRS)评分将患者分为预后不良组(mRS评分≥3分)52例、预后良好组(mRS评分<3分)158例。治疗前采用实时荧光定量PCR法检测CYP2C19基因多态性,时间分辨荧光免疫层析法检测血清NT-proBNP。用Pearson或Spearman分析CYP2C19基因多态性、血清NT-proBNP水平与mRS评分的相关性;用多因素Logistic回归分析ACI患者静脉溶栓预后的影响因素;用受试者工作特征曲线分析CYP2C19基因多态性、血清NT-proBNP水平对ACI患者静脉溶栓预后不良的预测价值。结果预后不良组年龄、高血压比例、糖尿病比例、入院美国国立卫生研究所脑卒中(NIHSS)评分、空腹血糖水平高于预后良好组(P均<0.05)。预后不良组和预后良好组CYP2C19基因多态性比较差异有统计学意义(P<0.05),预后不良组血清NT-proBNP水平高于预后良好组(P<0.05)。ACI患者CYP2C19基因多态性(r_(s)=0.362)、血清NT-proBNP水平(r=0.426)与mRS评分均呈正相关(P均<0.05)。高NIHSS评分、CYP2C19基因慢代谢型、高血清NT-proBNP水平是ACI患者预后不良的危险因素(P均<0.05)。CYP2C19基因多态性、血清NT-proBNP水平单独及联合预测ACI患者静脉溶栓预后的曲线下面积分别为0.752、0.786、0.861,二者联合预测的曲线下面积高于单独预测(P均<0.05)。结论CYP2C19基因多态性和高水平NT-proBNP是ACI患者静脉溶栓预后不良的危险因素,二者联合对不良预后有较高的预测价值。 展开更多
关键词 急性脑梗死 静脉溶栓 CYP2C19基因多态性 n末端B型脑利钠肽前体
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Botulinum toxin type A plus rehabilitative training for improving the motor function of the upper limbs and activities of daily life in patients with stroke and brain injury 被引量:1
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作者 Fei Guo Wei Yue Li Ren Yumiao Zhang Jing Yang 《Neural Regeneration Research》 SCIE CAS CSCD 2006年第9期859-861,共3页
BACKGROUND: Botulinum toxin type A (BTX-A) is mostly to be used to treat various diseases of motor disorders, whereas its effect on muscle spasm after stroke and brain injury needs further observation. OBJECTIVE: To o... BACKGROUND: Botulinum toxin type A (BTX-A) is mostly to be used to treat various diseases of motor disorders, whereas its effect on muscle spasm after stroke and brain injury needs further observation. OBJECTIVE: To observe the effect of BTX-A plus rehabilitative training on treating muscle spasm after stroke and brain injury. DESIGN: A randomized controlled observation. SETTINGS: Department of Rehabilitation, Department of Neurology and Department of Neurosurgery, the Second Hospital of Hebei Medical University. PARTICIPANTS: Sixty inpatients with brain injury and stroke were selected from the Department of Rehabilitation, Department of Neurology and Department of Neurosurgery, the Second Hospital of Hebei Medical University from January 2001 to August 2006. They were all confirmed by CT and MRI, and had obvious increase of spastic muscle strength in upper limbs, their Ashworth grades were grade 2 or above. The patients were randomly divided into treatment group (n =30) and control group (n =30). METHODS: ① Patients in the treatment group undertook comprehensive rehabilitative trainings, and they were administrated with domestic BTX-A, which was provided by Lanzhou Institute of Biological Products, Ministry of Health (S10970037), and the muscles of flexion spasm were selected for upper limbs, 20-25 IU for each site. ② Patients in the treatment group were assessed before injection and at 1 and 2 weeks, 1 and 3 months after injection respectively, and those in the control group were assessed at corresponding time points. The recovery of muscle spasm was assessed by modified Ashworth scale (MAS, grade 0-Ⅳ; Grade 0 for without increase of muscle strength; Grade Ⅳ for rigidity at passive flexion and extension); The recovery of motor function of the upper limbs was evaluated with Fugl-Meyer Assessment (FMA, total score was 226 points, including 100 for exercise, 14 for balance, 24 for sense, 44 for joint motion, 44 for pain and 66 for upper limb); The ADL were evaluated with Barthel index, the total score was 100 points, 60 for mild dysfunction, 60-41 for moderate dysfunction, < 40 for severe dysfunction). MAIN OUTCOME MEASURES: Changes of MAS grade, FMA scores and Barthel index before and after BTX-A injection. RESULTS: All the 60 patients with brain injury and stroke were involved in the analysis of results. ① FMA scores of upper limbs: The FMA score in the treatment group at 2 weeks after treatment was higher than that before treatment [(14.98±10.14), (13.10±9.28) points, P < 0.05], whereas there was no significant difference at corresponding time point in the control group. The FMA scores at 1 and 3 months in the treatment group [(23.36±10.69), (35.36±11.36) points] were higher than those in the control group [(20.55±10.22), (30.33±10.96) points, P < 0.01]. ② MAS grades of upper limbs: There were obviously fewer cases of grade Ⅲ in MAS at 2 weeks after treatment than before treatment in the treatment group (0, 9 cases, P < 0.05), whereas there was no obvious difference in the control group. There were obviously fewer cases of grade Ⅲ in MAS at 2 weeks and 1 month after treatment in the treatment group (0, 0 case) than the control group (5, 2 cases, P < 0.01). ③ Barthel index of upper limbs: The Barthel index at 2 weeks after treatment was higher than that before treatment in the treatment group [(30.36±22.25), (28.22±26.21) points, P < 0.05], whereas there was no significant difference in the control group. The Barthel indexes at 1 and 3 months after treatment in the treatment group were obviously higher than those in the control group [(20.55±10.22), (30.33±10.96) points, P < 0.01]. CONCLUSION: BTX-A has obvious efficacy on decreasing muscle tension after stroke and brain injury, and relieving muscle spasm; Meanwhile, the combination with rehabilitative training can effectively ameliorate the motor function of upper limbs and ADL of the patients. 展开更多
关键词 Botulinum toxin type A plus rehabilitative training for improving the motor function of the upper limbs and activities of daily life in patients with stroke and brain injury type
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区熔n型碲化铋材料的制备及性能优化
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作者 田源 汪波 +3 位作者 李存成 余健 桑夏晗 赵文俞 《材料科学与工程学报》 CAS CSCD 北大核心 2024年第2期186-192,212,共8页
本研究通过区熔法制备了一系列碘化物(SbI_(3),BiI_(3),TeI_(4))掺杂的n型Bi_(2)Te_(3-x)Se_x材料,发现碘化物掺杂能够有效稳定载流子类型,显著提高材料电导率,降低晶格热导率。当SbI_(3)、BiI_(3)、TeI_(4)掺杂量分别为0.14 wt%、0.12 ... 本研究通过区熔法制备了一系列碘化物(SbI_(3),BiI_(3),TeI_(4))掺杂的n型Bi_(2)Te_(3-x)Se_x材料,发现碘化物掺杂能够有效稳定载流子类型,显著提高材料电导率,降低晶格热导率。当SbI_(3)、BiI_(3)、TeI_(4)掺杂量分别为0.14 wt%、0.12 wt%和0.07 wt%时,材料在405、350和362 K时获得最大ZT值0.85、1.05和0.96,比商用n型材料分别提高了21%,36%和28%。 展开更多
关键词 n型碲化铋 区熔法 碘化物掺杂 热电性能
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Driving characteristics of octagon-type ultrasonic motor 被引量:1
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作者 KIM Jong-Wook PARK Choong-Hyo +3 位作者 LIM Jung-Hoon JEONG Seong-Su PARK Jong-Kyu PARK Tae-Gone 《Journal of Central South University》 SCIE EI CAS 2013年第1期71-75,共5页
Structure of the octagon-type ultrasonic motor was proposed and designed so as to allow the motor to drive small actuator. The stator of the motor consisted of the octagon shape elastic body and four rectangular plate... Structure of the octagon-type ultrasonic motor was proposed and designed so as to allow the motor to drive small actuator. The stator of the motor consisted of the octagon shape elastic body and four rectangular plate ceramics. The four ceramics were attached to outer surfaces of the octagon elastic body. The same phase voltages were applied to the ceramics on horizontal surfaces, and 90° phase difference voltages were applied to the ceramics on vertical surfaces. When the AC voltage with 90° phase difference was applied in ceramics, the elliptical displacement of unimorph bars was generated by generating bending vibration. To find the maximum displacement model that generates elliptical displacement at the centers of the inner surfaces, the finite element analysis program ATILA was used. The analyzed results were compared to the experimental results. As a result, the speed and torque are increased linearly by increasing the input voltage and the speed of motors can be controlled by changing the applied voltages. 展开更多
关键词 超声波马达 驾驶特性 超声波电动机 有限元分析程序 陶瓷连接 输入电压 外表面 相位差
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NT-proBNP峰值超上限的急性心肌梗死患者院内和远期预后分析
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作者 刘江红 王刚 +1 位作者 范继红 刘锐锋 《国际检验医学杂志》 CAS 2024年第4期397-403,共7页
目的 分析N末端B型脑钠肽前体(NT-proBNP)峰值超上限的急性心肌梗死(AMI)患者院内和远期预后。方法 选取2013-2018年该院确诊的AMI患者共669例作为研究对象,根据NT-proBNP峰值水平分为NT-proBNP峰值超上限组(50例)和NT-proBNP峰值可检测... 目的 分析N末端B型脑钠肽前体(NT-proBNP)峰值超上限的急性心肌梗死(AMI)患者院内和远期预后。方法 选取2013-2018年该院确诊的AMI患者共669例作为研究对象,根据NT-proBNP峰值水平分为NT-proBNP峰值超上限组(50例)和NT-proBNP峰值可检测组(619例)。使用倾向性评分进行匹配(1∶2),分为NT-proBNP峰值超上限组(50例)、NT-proBNP峰值可检测组(107例),比较两组院内预后及远期预后,以及AMI急性期和恢复期各组超声心动指标,应用多重线性回归分析预测影响AMI恢复期左心室射血分数的因素。结果 倾向性评分匹配后,与NT-proBNP峰值可检测组比较,NT-proBNP峰值超上限组入院时中性粒细胞比淋巴细胞比值、超敏C反应蛋白水平及纤维蛋白原水平均较高,差异有统计学意义(P<0.05)。NT-proBNP峰值超上限组Killip≥Ⅱ级占比、左心室射血分数、住院时间、主要不良心脑血管事件占比与NT-proBNP峰值可检测组比较,差异有统计学意义(P<0.05)。AMI急性期NT-proBNP峰值可检测组左心室射血分数、左心室缩短分数均高于AMI急性期NT-proBNP峰值超检测上限组,差异有统计学意义(P<0.05)。多重线性回归分析,患者住院期间的NT-proBNP峰值和AMI恢复期心功能左心室射血分数的关系,结果提示NT-proBNP峰值不是影响患者AMI恢复期心功能左心室射血分数的危险因素。结论 NT-proBNP峰值超上限的AMI患者在住院期间,临床上应对其实施一系列综合性的治疗策略,以促进其康复,改善患者长期预后。 展开更多
关键词 n末端B型脑钠肽前体 急性心肌梗死 预后
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Experimental Study on Rotation Resistance Coefficient of Motor Bogie for Type A Vehicle
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作者 Fuxing Tan Hongtao Liu +2 位作者 Shihui Liu Zhenchuan Zhang Peng Zhang 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2019年第2期90-96,共7页
Rotation resistance coefficient is an important operating parameter for vehicle bogies, which influences the dynamic behavior of vehicles directly. A research on the rotation resistance coefficient of type A vehicle m... Rotation resistance coefficient is an important operating parameter for vehicle bogies, which influences the dynamic behavior of vehicles directly. A research on the rotation resistance coefficient of type A vehicle motor bogies was conducted by means of theoretical calculation, dynamic simulation, test certification, and so on. Result of the simulation analysis shows that the rotation resistance coefficient relates to air springs stiffness and negotiated curve radii, and it varies proportionally with the change of air springs horizontal stiffness. The greater the rotation angle is, the greater the factor becomes. The certifications made under the operating conditions(e.g., different air spring status, different rotation speeds) indicate that the rotation resistance coefficient increases with the increase of the rotation speed. The anti-yaw dampers can contribute to the rotation resistance torque acted on bogie, and the greater the rotation speeds are, the greater the torque generated by the anti-yaw dampers is. The results suggest that the theoretical analysis and dynamics simulation are in accordance with the results from the bogie bench tests, which meet the requirements in EN14363 and the indicators in vehicles safe operation. 展开更多
关键词 type A VEHICLE motor BOGIE ROTATIOn angle ROTATIOn resistance COEFFICIEnT ROTATIOn SPEED
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A ring type standing wave ultrasonic motor using cantilever type longitudinal transducers
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作者 刘英想 刘军考 +1 位作者 陈维山 石胜君 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2011年第1期52-56,共5页
The disadvantages of classic ring type ultrasonic motor were analyzed.To obtain large mechanical output power,a ring type standing wave ultrasonic motor using cantilever type longitudinal transducers was proposed.Ther... The disadvantages of classic ring type ultrasonic motor were analyzed.To obtain large mechanical output power,a ring type standing wave ultrasonic motor using cantilever type longitudinal transducers was proposed.There are four pairs of cantilevers on one side of the ring,and four PZT ceramics are set between each pair of cantilevers.A screw fastened the PZT ceramics and cantilevers together to form a longitudinal transducer.The bending vibration mode of the ring is excited by the stretching vibration of the PZT ceramics.Thus,linear simple harmonic motions are achieved at the particle on the teeth.And the driving force is the frictional force between rotor and stator.The working principle of the proposed motor was analyzed.The ring and the longitudinal transducer were designed with FEM.The sensitive parameters of resonant frequency of the transducer and ring could be gained with modal analysis.The longitudinal vibration modal of transducer and bending vibration modal of ring were degenerated,and the motion trajectories of nodes on the teeth were analyzed.The results of this paper could guide the development of this new type of motor. 展开更多
关键词 ultrasonic motor standing wave ring type vibration characteristic FEM
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开窍活血汤联合阿替普酶对急性脑梗死患者认知功能及血清NT-proBNP和sICAM-1的影响
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作者 朱智恒 罗凯 +2 位作者 刘用 王璐 李春辉 《中国药业》 CAS 2024年第5期54-58,共5页
目的探讨开窍活血汤联合阿替普酶(rt-PA)对急性脑梗死(ACI)患者认知功能及血清N-末端B型脑钠肽前体(NT-proBNP)、可溶性细胞间黏附分子-1(sICAM-1)水平的影响。方法选取湖南中医药大学第一附属医院2022年1月至12月收治的ACI患者100例,... 目的探讨开窍活血汤联合阿替普酶(rt-PA)对急性脑梗死(ACI)患者认知功能及血清N-末端B型脑钠肽前体(NT-proBNP)、可溶性细胞间黏附分子-1(sICAM-1)水平的影响。方法选取湖南中医药大学第一附属医院2022年1月至12月收治的ACI患者100例,按随机数字表法分为观察组和对照组,各50例。两组患者均予rt-PA溶栓治疗联合常规治疗,观察组患者加用开窍活血汤,两组患者均治疗2周。结果观察组总有效率为96.00%,显著高于对照组的82.00%(P<0.05)。治疗后,两组患者的口舌歪斜、半身不遂、言语謇涩、面色皎白、舌质暗淡、脉沉细等中医证候积分均显著降低,且观察组显著低于对照组(P<0.05);两组患者美国国立卫生研究院卒中量表(NIHSS)评分显著降低,简易智能精神状态评估量表(MMSE)评分显著升高,且观察组显著优于对照组(P<0.05);两组患者NT-proBNP和sICAM-1水平均显著降低(P<0.05),且观察组显著低于对照组(P<0.05)。观察组患者治疗期间不良反应发生率为6.00%,显著低于对照组的20.00%(P<0.05)。结论开窍活血汤联合rt-PA治疗ACI的临床疗效显著,可有效缓解患者的临床症状和体征,改善其神经功能及认知功能,降低血清NT-proBNP和sICAM-1水平,且安全性良好。 展开更多
关键词 开窍活血汤 阿替普酶 急性脑梗死 n-末端B型脑钠肽前体 可溶性细胞间黏附分子-1
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基于n型柔性半导体的有机晶体管及其电子-离子双响应特性
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作者 蒋浩 钟岳桁 +1 位作者 王刚 王宏志 《东华大学学报(自然科学版)》 CAS 北大核心 2024年第1期39-44,共6页
为了研究n型有机混合离子电子导体电子-离子双响应特性及分子量对载流子迁移率的影响,采用具有平面刚性的梯形分子链结构的高分子量聚苯并二咪唑苯并菲绕啉二酮制备高性能有机电化学晶体管,并对晶体管紫外可见吸收光谱和晶体管器件电气... 为了研究n型有机混合离子电子导体电子-离子双响应特性及分子量对载流子迁移率的影响,采用具有平面刚性的梯形分子链结构的高分子量聚苯并二咪唑苯并菲绕啉二酮制备高性能有机电化学晶体管,并对晶体管紫外可见吸收光谱和晶体管器件电气性能进行表征。结果表明,利用高分子量聚苯并二咪唑苯并菲绕啉二酮制备的n型有机电化学晶体管表现出极高的响应速度(0.034 s)、高载流子迁移率(4.72×10^(-3) cm^(2)/(V·s)),以及在水系电解液中优异的稳定性(稳定运行超过120次脉冲循环)。 展开更多
关键词 有机晶体管 n型柔性半导体 电子-离子双响应特性 聚苯并二咪唑苯并菲绕啉二酮 载流子迁移率
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酒石酸美托洛尔对慢性心力衰竭治疗前后NT-proBNP变化的临床效果 被引量:1
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作者 李拥政 《中国医药指南》 2024年第4期83-86,共4页
目的 分析慢性心力衰竭患者应用酒石酸美托洛尔治疗前后N末端B型利钠肽前体(NT-pro BNP)的变化。方法 选取112例本院收治的慢性心力衰竭患者为对象展开研究,入院时间为2022年5月至2023年5月,所有患者通过交替分组法划分成两组,在临床中5... 目的 分析慢性心力衰竭患者应用酒石酸美托洛尔治疗前后N末端B型利钠肽前体(NT-pro BNP)的变化。方法 选取112例本院收治的慢性心力衰竭患者为对象展开研究,入院时间为2022年5月至2023年5月,所有患者通过交替分组法划分成两组,在临床中56例参照组患者使用常规药物治疗,剩余56例试验组患者同时使用酒石酸美托洛尔进行治疗,对比临床疗效和治疗前后的NT-proBNP水平、心功能指标变化。结果 治疗后,试验组患者治疗后的NT-proBNP水平低于治疗前,同时低于参照组(P<0.05)。治疗后,试验组患者比参照组的LVEF更高,比参照组的LVSAD和LVEDD更底(P<0.05)。治疗后,两组患者心率、收缩压、舒张压均下降,但试验组水平更低(P<0.05)。试验组患者总有效率为94.64%,低于参照组的80.36%(P<0.05)。试验组有5.36%的患者发生药物不良反应,参照组则为1.79%,无统计学差异(P>0.05)。结论 慢性心力衰竭患者在临床治疗中应用酒石酸美托洛尔,有助于下调NT-proBNP水平,改善心功能。 展开更多
关键词 酒石酸美托洛尔 慢性心力衰竭 n末端B型利钠肽前体
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A Study on the Composite Type Piezoelectric Motor
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作者 Jwo Ming Jou 《Open Journal of Acoustics》 2013年第3期88-95,共8页
This study is to explore a composite type piezoelectric motor. Its main structures include the piezoelectric stator, rotor, the preload adjusting module and shaft. Wherein the piezoelectric stator is made base, the co... This study is to explore a composite type piezoelectric motor. Its main structures include the piezoelectric stator, rotor, the preload adjusting module and shaft. Wherein the piezoelectric stator is made base, the composite type actuating element and stator formed. As the composite type actuating element is set by the axial vibration type actuating element, horizontal bending vibration type actuating element and vertical bending vibration type actuating element formed. The stator is an empty cylinder with a waist and tapered hole. In addition, the rotor is a kind of a hollow cone. It can be through the preload adjusting module to withstand the stator. As the preload adjusting module is set by the limit element, spring, washer and nut formed. While the shaft is a kind of cylinder with screw thread and stopper, it can pass through the piezoelectric stator, rotor and the preload adjusting module, making it a composite type piezoelectric motor. When we provide appropriate driving voltage, frequency, loading and phase angle to the piezoelectric stator, we can let the piezoelectric motor produces rapid rotation. Of course, we can also change through the driving phase angle, to change the direction of rotation of the piezoelectric motor. According to the experimental results, we found that its maximum speed and loading are 480 rpm and 2305 gw under conditions of 180 Vp-p, 35 kHz and 00 driving phase angle. Most importantly, we also found that the composite type piezoelectric motor has a very good conversion efficiency of the driving phase angle. 展开更多
关键词 Composite type Piezoelectric motor AXIAL VIBRATIOn type Actuating ELEMEnT HORIZOnTAL BEnDInG VIBRATIOn type Actuating ELEMEnT Vertical BEnDInG VIBRATIOn type Actuating ELEMEnT
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