交互式数字叙事:加拿大Writing New Body Worlds阅读治疗新探索

文章基于相关研究文献与语料,对加拿大WNB阅读治疗实践进行梳理与归纳。WNB首次使用交互式数字叙事技术,构建面向公众的阅读治疗平台,以其交互式特征,融合了阅读和治疗引导两个过程,提供可访问的非临床方式,可面向大规模人群实现预防性健康干预。基于数据与计算的精准化阅读治疗是数字人文视角下的新变革,更具推广应用价值;以在线阅读平台建设为依托,推进实施平台化的阅读和治疗应成为未来发展方向之一;基于阅读形态与体验因技术赋能而改变的现状,图书馆应发挥引领作用,积极收集、创建或协助创建数字故事,推进阅读推广、服务与治疗的融合性发展,成为社区建设促进者、历史欣赏者和社区参与倡导者,也使阅读借助交互式数字叙事这一新载体,更好地发挥变革的力量,促进健康与幸福。

网络新媒体视阈下客家议题在日传播特征分析——基于日本Google News的考察

以日本Google News中的客家相关日文报道为语料,通过文本挖掘工具KH Coder进行文本数据挖掘,发现日本网络新闻媒体的客家议题日文报道具有分布零散性及以图片报道为主的特点。报道关注的客家区域主要涉及台湾地区、福建、香港地区、广东等地,其中,台湾地区的客家关注度最高。报道聚焦客家的观光旅游、产业振兴、客家书籍出版等相关内容,形成了客家传统建筑类、台湾地区客家文化交流类、客家文学作品推介类、客家观光旅游类等四大主要议题。本文提出要充分运用Google News等网络新媒体强大的技术功能和传播优势加大客家文化的传播力度。

Defects of Traditional Marketing Model and New Consumer Experience Requirements in the Context of"New Retail"

With the concept of"new retail"and the rapid development of"new retail"format,the defects of traditional marketing models such as advertising marketing,direct marketing and e-commerce marketing are becoming more and more obvious,which has seriously hindered the further development of the consumer retail industry.At the same time,under the background of"new retail",the industry demand based on the improvement of consumer experience is increasingly characterized by consumer entertainment,consumer autonomy,consumer personalization,and consumer socialization,which provides ideas and reference for the construction of new marketing models in the consumer retail industry.

Research on the Future Trend of New Retail and E-commerce

In the rapid development of information technology,the term new retail was derived based on online shopping,and as the creator of largest online shopping platform in China,Ma Yun,made a related concept discussion on new retail,which caused a great response in the whole society.Therefore,this paper will study the future development trend of the new retail model,as well as the controversy existing in the new retail itself and many successful cases.Through analysis and discussion,the paper will discuss the future development of new retail and e-commerce trends.

Endoscopic diagnosis and management of gallbladder carcinoma in minimally invasive era:New needs,new models

Gallbladder cancer(GBC)is a rare and lethal malignancy;however,it represents the most common type of biliary tract cancer.Patients with GBC are often diagnosed at an advanced stage,thus,unfortunately,losing the opportunity for curative surgical intervention.This situation leads to lower quality of life and higher mortality rates.In recent years,the rapid development of endoscopic equipment and techniques has provided new avenues and possibilities for the early and minimally invasive diagnosis and treatment of GBC.This editorial comments on the article by Pavlidis et al.Building upon their work,we explore the new needs and corresponding models for managing GBC from the endoscopic diagnosis and treatment perspective.

Opportunities,Challenges and Countermeasures proposed for the new retail industry in The COVID-19

It has been four years since the concept of“new retail”was proposed,and the layout of“new retail”of several major domestic enterprises has been intensified,which has a“unique landscape”compared to the foreign retail landscape.The trend,however,the sudden outbreak and continued spread of the COVID-19 has dealt a serious blow to the global economic development,from the domestic point of view,the epidemic caused by the decline in GDP,leading to a negative year-on-year growth in the total retail sales of consumer goods,the new retail industry is still in the development stage suffered a blow.On the other hand,however,the sinking of the new retail market driven by the consumer economy,the surge of private domain traffic on platforms and the rise of the“house economy”prompted the new retail industry to create new development opportunities during the epidemic,clarifying the development of the new retail industry in the post-epidemic era and pointing out the direction.

Boehmeria nivea var. strigosa (Urticaceae), a new variety from Southwest China

Boehmeria nivea var.strigosa Zeng Y.Wu&Y.Zhao,a new variety of B.nivea(Urticaceae)from Southwest China,is here described based on evidence from morphology and molecular phylogeny.This new variety is mainly characterized by its green abaxial leaf blade,partly connate stipules,and densely patent strigose hairs on stems and potioles.The phylogenetic analysis based on rbc L,nrDNA and rbc L+nrDNA datasets,revealed that all individuals of B.nivea var.strigosa formed a monophyletic group.The conservation status of B.nivea var.strigosa is assessed as“Near Threatened”(NT)according to IUCN evaluation criteria.The discovery of this new variety is not only crucial for the taxonomy of ramie,but also provides reference for the exploration and utilization of ramie.

The Role of New Retailing Formats in the Italian Local Development

In Italy, and particularly in its southern area, super-markets and hyper-markets still represent an expanding retailing format, as they were introduced years later than in other western countries. Today, they have become large retailers capable of influencing local development from an economic, social and urban perspective. The literature concerned with their effects on the local economy has focused on labour markets, price dynamics, and inter-type competition, neglecting their impact on macroeconomic factors such as GDP, value added specific sectors--agriculture, industry and services. This study tries to contribute to fill this gap by empirically investigating associations between key characteristics of these retailers and specific macroeconomic value added factors

New direction for surgery:Super minimally invasive surgery

The top goal of modern medicine is treating disease without destroying organ structures and making patients as healthy as they were before their sickness.Minimally invasive surgery(MIS)has dominated the surgical realm because of its lesser invasiveness.However,changes in anatomical structures of the body and reconstruction of internal organs or different organs are common after traditional surgery or MIS,decreasing the quality of life of patients post-operation.Thus,I propose a new treatment mode,super MIS(SMIS),which is defined as“curing a disease or lesion which used to be treated by MIS while preserving the integrity of the organs”.In this study,I describe the origin,definition,operative channels,advantages,and future perspectives of SMIS.

An Update on the Clinical Pipelines of New Antibacterial Drugs Developed in China

Antibacterial resistance is a global health threat that requires further concrete action on the part of all countries.In this context,one of the biggest concerns is whether enough new antibacterial drugs are being discovered and developed.Although several high-quality reviews on clinical antibacterial drug pipelines from a global perspective were published recently,none provides comprehensive information on original antibacterial drugs at clinical stages in China.In this review,we summarize the latest progress of novel antibacterial drugs approved for marketing and under clinical evaluation in China since 2019.Information was obtained by consulting official websites,searching commercial databases,retrieving literature,asking personnel from institutions or companies,and other means,and a considerable part of the data covered here has not been included in other reviews.As of June 30,2023,a total of 20 antibacterial projects from 17 Chinese pharmaceutical companies or developers were identified and updated.Among them,two new antibacterial drugs that belong to traditional antibiotic classes were approved by the National Medical Products Administration(NMPA)in China in 2019 and 2021,respectively,and 18 antibacterial agents are in clinical development,with one under regulatory evaluation,five in phase-3,six in phase-2,and six in phase-1.Most of the clinical candidates are new analogs or monocomponents of traditional antibacterial pharmacophore types,including two dual-acting hybrid antibiotics and a recombinant antibacterial protein.Overall,despite there being 17 antibacterial clinical candidates,our analysis indicates that there are still relatively few clinically differentiated antibacterial agents in stages of clinical development in China.Hopefully,Chinese pharmaceutical companies and institutions will develop more innovative and clinically differentiated candidates with good market potential in the future research and development(R&D)of original antibacterial drugs.

Mental retardation,seizures and language delay caused by new SETD1B mutations:Three case reports

BACKGROUND The SETD1B gene is instrumental in human intelligence and nerve development.Mutations in the SETD1B gene have been linked in recent studies to neurodevelopmental disorders,seizures,and language delay.CASE SUMMARY This study aimed to analyze the clinical manifestations and treatment of three patients suffering from mental retardation,epilepsy,and language delay resulting from a new mutation in the SETD1B gene.Three individuals with these symptoms were selected,and their clinical symptoms,gene test results,and treatment were analyzed.This article discusses the impact of the SETD1B gene mutation on patients and outlines the treatment approach.Among the three patients(two females and one male,aged 8,4,and 1,respectively),all exhibited psychomotor retardation,attention deficit,and hyperactivity disorder,and two had epilepsy.Antiepileptic treatment with sodium tripolyvalproate halted the seizures in the affected child,although mental development remained somewhat delayed.Whole exome sequencing revealed new mutations in the SETD1B gene for all patients,specifically with c.5473C>T(p.Arg1825trp),c.4120C>T(p.Gln1374*,593),c.14_15insC(p.His5Hisfs*33).CONCLUSION Possessing the SETD1B gene mutation may cause mental retardation accompanied by seizures and language delay.Although the exact mechanism is not fully understood,interventions such as drug therapy,rehabilitation training,and family support can assist patients in managing their symptoms and enhancing their quality of life.Furthermore,genetic testing supplies healthcare providers with more precise diagnostic and therapeutic guidance,informs families about genetic disease risks,and contributes to understanding disease pathogenesis and drug research and development.

Comprehensive Evaluation of Flower Border Application Value of New and Superior Plants in Hefei Area

An analytic hierarchy process(AHP)was employed to assess the applicability of 18 new and superior varieties of flowers in Hefei City flower border applications.A total of 12 indicators were selected from three distinct aspects of adaptability,ornamental characteristics and use traits,in order to establish a comprehensive evaluation model.The results demonstrate that grade I(J≥2.685)exhibits excellent application value,encompassing six species of plants,such asHydrangeamacrophylla‘Endless Summer’;grade II(2.684≤J≤2.420)is also of notable application value,encompassing five species of plants,such asCallistemonrigidus;grade III(2.419≤J≤2.615)is of average application value,including five species of plants,such asCrocosmiacrocosmiflora;grade IV(J≤2.16)is of relatively poor application value.The evaluation results may be utilized as a theoretical reference for the promotion of new and superior varieties in the flower border of Hefei.

Is Online Retaining Really Necessary to Make New Retail Successful

Preface It’s always been a big problem for terminal retail stores to find a method to deal with the Nov.11 shopping carnival that makes all feel excited in China.I couldn’t help but think about at this time last year,all retail stores made sales promotion of“original price for the first one while 90%off for the second”or all sold at 50%off.Nevertheless,it cannot contend with online retailing.

A new diatom genus Spargeria gen.nov.(Bacillariophyceae)from Xizang,China,and the description of two new species

During our investigation of diatom biodiversity in Xizang,two species exhibited unique morphological features discriminative from all previously known genera.Herein we describe these two species and describe as new the genus,Spargeria gen.nov.The new genus features narrow to wide rectangular valves,narrow valve mantles,filiform raphe branches that occur on the valve face only,terminal raphe fissures straight or slightly deflected to same side,bow-tie shaped central areas,chambered striae present on the valve face only,being absent from the mantle,wider striae near the axial area and very narrow near the margin,multiseriate striae with small and round areolae that are occluded externally.Comparatively,Spargeria zhuii sp.nov.has larger and robust valves,radiate striae,with one divergent stria near the apices,while Spargeria chenia sp.nov.is smaller,with narrow valves,striae slightly radiate in the middle,becoming convergent or parallel near apices.This new genus belongs to the family Pinnulariaceae,and it was compared and contrasted with other genera of this family.Our work suggests the need for continued studies to document the biodiversity of diatoms in Xizang.

Lineaperpetua gen.nov.:a new diatom genus in the Thalassiosirales supported by morphology and molecular data

Based on a combination of morphology and molecular data of ribosomal DNA genes,a new diatom genus Lineaperpetua gen.nov.Yu,You,Kociolek&Wang is described.The features that help define Lineaperpetua at the level of genus include:a tangentially undulated valve face;continuous cribra areolae on the valve interior consisting of pores arranged as strips;single rimoportula located inside the ring of marginal fultoportulae.Additionally,phylogenetic analysis based on nuclear small subunit(SSU)rDNA sequences and nuclear large subunit(LSU)rDNA gene placed the three strains of L.lacustris in a single,monophyletic clade at a considerable sequence distance from the other genera(Thalassiosira,Conticribra,Planktoniella,Shinodiscus,and other genera)belonging to Thalassiosirales.Despite the similarities with some species of Thalassiosira,Conticribra,and Spicaticribra,the suite of features found in Lineaperpetua differentiate it from these other genera.These molecular data and morphological characters suggest an affinity of the new genus to the Thalassiosiraceae.

Two new Stephanodiscaceae species(Bacillariophyta)from SW China

Two new freshwater centric diatom species were described from the southwest of China based on light and scanning electron microscopy.Pliocaenicus weixiense sp.nov.has a transversely undulate valve face,marginal fultoportulae situated at the end of the hyaline strips,central fultoportulae forming a ring positioned in a circular pattern,each with 3-4(usually 3)satellite pores,and a single rimoportula located at the base of the inner distal end of the costa.Tertiarius aspera sp.nov.has an uneven valve face with small granules that may be present on the marginal area and valve mantle,marginal fultoportulae situated on each costa close to the margin of the valve,6-7 central fultoportulae forming a ring near the valve center each with two satellite pores,and one rimoportula located on the valve face/mantle junction in the middle of costa on the internal valve.T.aspera sp.nov.is the first reported extant species in the genus.This study played an important role in studying the taxonomic status and ecological information of the genus,and the establishment of the two new taxa will help demonstrate the unique nature of freshwater diatom flora in the southwest of China.

New insights and investigation:Morphomolecular notes on the infraciliature,taxonomy,and systematics of pleurostomatid ciliates(Protozoa,Ciliophora),with establishment of a new suborder,two new genera,and three new species

Pleurostomatid ciliates,as a highly diverse and widely distributed unicellular eukaryote group,play a crucial role in the cycling of nutrients and energy in microbial food webs.However,research on pleurostomatids remains insufficient,resulting in a paucity of molecular information and substantial gaps in knowledge of their phylogenetic relationships.In recent years,we investigated pleurostomatid diversity in various Chinese habitats,including their systematic relationships and taxonomic circumscriptions,which were comprehensively analyzed using an integrative morphomolecular approach.Results revealed that:(1)pleurostomatids can be categorized into two suborders,Protolitonotina subord.nov.and Amphileptina Jankowski,1967;(2)Protolitonotina subord.nov.represents the ancestral pleurostomatid group and includes two genera,Protolitonotus and Heterolitonotus gen.nov.,characterized by right kineties progressively shortened along rightmost full kineties and absence of a left dorsolateral kinety;(3)Heterolitonotus gen.nov.represents an orphan lineage and is defined by an oral slit extending to its dorsal margin;(4)“Protolitonotus clampi”does not group with congeners but instead represents an orphan lineage,thus Novilitonotus gen.nov.is established to which P.clampi is transferred as Novilitonotus clampi comb.nov.;(5)three new species,Apoamphileptus paraclaparedii sp.nov.,Heterolitonotus rex gen.nov.,sp.nov.,and Loxophyllum apohelus sp.nov.,are described;and(6)helices 21es6a to 21es6d within the V4 region of small subunit ribosomal RNA(SSU rRNA)may serve as a useful tool for discriminating pleurostomatids.The evolutionary relationships among all main lineages of pleurostomatids are discussed and a key to the identification of pleurostomatid genera is provided.

A new infrageneric classification of Gastrochilus(Orchidaceae:Epidendroideae)based on molecular and morphological data

Gastrochilus is an orchid genus containing 73 species of mainly epiphytic on trees or rocks in mountain forests of tropical and subtropical Asia.Previous phylogenetic analyses and morphological assessments have failed to produce a well-resolved phylogeny at the infrageneric level.In the present study,a new infrageneric classification of Gastrochilus is proposed based on thoroughly morphological and phylogenetic analyses based on 52 species.Our phylogenetic analysis divided the genus into six sections including three new sections,G.sect.Pseudodistichi,G.sect.Brachycaules and G.sect.Acinacifolii.We also reinstate G.suavis to the specific rank.Furthermore,two new species,G.armeniacus Jun Y.Zhang,B.Xu&Yue H.Cheng and G.minjiangensis Jun Y.Zhang,B.Xu&Yue H.Cheng,are described and illustrated.A key to six sections of the genus is presented.

Taxonomy of Two New Peritrich Ciliates(Protozoa:Ciliophora)from Inland Saltwaters of China

The inland saltwater lakes harbor exceptional biodiversity.Here,two new species of solitary sessile peritrich ciliates were isolated from Qinghai Lake,the largest inland saltwater lake in China.Their morphology,ciliature,silverline system,and molecular phylogeny were investigated based on live observation,silver staining,and analysis of the small subunit ribosomal DNA(SSU rDNA).Vorticella paraglobosa sp.n.is characterized mainly by its obconical or elongate bell-shaped zooid,C-shaped macronucleus,single ventrally located contractile vacuole,two-rowed infundibular polykinety 3,and 28-38 silverlines between peristome and aboral tro-chal band and 10-15 between aboral trochal band and scopula.Vorticella cotyliformis sp.n.differs from its congeners mainly by its double-layered peristomial lip,cup-shaped zooid,J-shaped macronucleus,single ventrally positioned contractile vacuole,three-rowed infundibular polykinety 3,and 70-85 silverlines between peristome and aboral trochal band and 21-25 between aboral trochal band and scopula.The SSU rDNA sequences of the two new species were obtained,and the subsequent molecular phylogenetic analysis supported their taxonomic classification.

Yuzaoea gen. nov., a new biraphid diatom(Bacillariophyceae)genus and its phylogenetic significance

The flexed frustules in pennate diatoms are usually associated with monoraphid diatoms. Interestingly, we found a biraphid diatom species with flexed frustules in an offshore intertidal beach environment on Weizhou Island,Beihai City, Guangxi Zhuang Autonomous Region, China. Therefore, based on morphological characteristics, we described a new genus of diatoms Yuzaoea sinensis gen. et sp. nov. CH Li, HH Liu, YH Gao & CP Chen. The frustule of this genus is characterized by heterogeneous frustule with one concave valve and one convex valve,complete raphe on both valves, straight and moderately eccentric raphe, uniseriate striae and girdle bands with a single row of areolae. The most identifying feature of this genus was the flexed frustule, which is rare in biraphid diatoms and common in monoraphid diatoms. We compared the morphometric characteristics of genus Yuzaoea with genus Rhoikoneis and several genera within the family Rhoicospheniaceae, including Rhoicosphenia,Campylopyxis, and Cuneolus. Phylogenetic analyses based on SSU rRNA and rbc L showed that the genus Yuzaoea was the sister group to the clade of Rhoicosphenia with a high support value(bootstrap values = 100%), and the clade “Yuzaoea+Rhoicosphenia” was sister to the clade of monoraphid diatoms, in which the genera Achnanthidium, Planothidium and some Cocconeis with high support values(bootstrap = 100%).Morphologically, the genus Yuzaoea shares many morphological features with monoraphid diatoms like genera Achnanthidium and Planothidium and the members within the Rhoicospheniaceae. Therefore, based on a combined morphological studies and phylogenetic results we suggested that this branch may represented the evolution of one kind monoraphid diatoms, from biraphid diatoms(e.g. genus Yuzaoea), to incompleted biraphid diatoms(e.g. genera Rhoicosphenia, Campylopyxis), to monoraphid diatoms(e.g. genera Achnanthidium and Planothidium).