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FIRST简易版虚弱评估量表评分在新诊断多发性骨髓瘤患者中的应用价值分析
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作者 姚琼 王鑫炜 +4 位作者 杨慧 李林宇 赵洁 贺少龙 田卫伟 《中国临床新医学》 2024年第2期186-191,共6页
目的分析FIRST简易版虚弱评估量表评分在新诊断多发性骨髓瘤(NDMM)患者中的应用价值。方法回顾性分析2014年7月1日至2021年12月31日山西医科大学第三医院收治的131例NDMM患者的临床资料。根据FIRST简易版虚弱评估量表评分将其分为虚弱组... 目的分析FIRST简易版虚弱评估量表评分在新诊断多发性骨髓瘤(NDMM)患者中的应用价值。方法回顾性分析2014年7月1日至2021年12月31日山西医科大学第三医院收治的131例NDMM患者的临床资料。根据FIRST简易版虚弱评估量表评分将其分为虚弱组(50例)和非虚弱组(81例)。比较两组患者疗效、累积早期≥3级感染发生率及生存预后情况。并对接受硼替佐米为基础诱导治疗方案的患者进行亚组分析。结果两组疗效为≥非常好的部分缓解(VGPR)的人数比例差异无统计学意义(45.68%vs 36.00%,P>0.05)。虚弱组和非虚弱组分别有26例(52.00%)和27例(33.33%)发生早期≥3级感染,虚弱组早期≥3级感染相关预后更差(log-rank检验:χ^(2)=4.472,P=0.020)。虚弱组中位总生存(OS)时间和中位无进展生存(PFS)时间均短于非虚弱组(36个月vs 81个月;16个月vs 34个月),非虚弱组生存预后情况显著优于虚弱组(P<0.05)。在接受硼替佐米为基础诱导方案治疗的100例患者中,虚弱组中位OS时间和中位PFS时间均短于非虚弱组(34个月vs 84个月;15个月vs 33个月),非虚弱组生存预后情况显著优于虚弱组(P<0.05)。结论FIRST简易版虚弱评估量表评分对NDMM患者有较好的应用价值。 展开更多
关键词 多发性骨髓瘤 first简易版虚弱评估量表 虚弱 感染 预后
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Community Knowledge and Attitude about Burns First Aid (BFA) in Jazan, Saudi Arabia
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作者 Md. Mazharul Hoque Mohamed E. Moukhyer +9 位作者 Nizar A. Khamjan Bahja Al Siddig Elsie Maguen Shane Alam Abdulrahman Ibrahim Ali Hakami Siraj Yahya Mohammed Mobarki Bandar Hassan Sulaiman Ghazwani Ayman Abdulrhman Alhathiq Lamyaa El Hassan Aziza Mukhayer 《Journal of Biosciences and Medicines》 2024年第4期135-148,共14页
Introduction and Significance: Burn injury (BI) is a considerable health issue which is responsible for around 300,000 deaths and affecting about 11 million people every year worldwide. In Saudi Arabia, the prevalence... Introduction and Significance: Burn injury (BI) is a considerable health issue which is responsible for around 300,000 deaths and affecting about 11 million people every year worldwide. In Saudi Arabia, the prevalence of BIs array from 112 to 518 per 100,000 per year. The appropriate awareness of performing first aid could facilitate to improve the outcomes of burns. Purpose and Objectives: To appraise the community that acknowledges burns, first aid, and associated factors among the community population in Jazan City, Saudi Arabia. The paper aims to identify limitations to encourage additional research and persuade legislators to develop improved burn-injury care recommendations and training programs. Materials and Methods: An observational-based sample survey was conducted among the people who live in Jazan City aging 13 years or more, during April 5 to May 5, 2023. Data collection was done by a validated online self-administrated questionnaire sent randomly to community members in different parts of Jazan City via social media platforms. Collected data were coded and cleaned by an excel program, and finally exported on SPSS 26.0 software. The variables were analyzed using descriptive statistics like frequencies and percentages. Also, the Chi-square test was used to investigate the relation between different variables, with a significance value of P Results: This study included 243 participants (about 62%) among them were mostly male participants (151) having a university degree. The majority of participants 75% did not take any form of BFA training in the past. This study shows that 69.9% of the participants have inadequate awareness, despite 72% having a constructive attitude towards burn first aid. Previous burn-related first aid training was significantly associated with participants’ knowledge of BFA at a p-value less than 0.05. Conclusion: This study indicates a high frequency of Jazan population having inadequate knowledge of burn first aid despite the high prevalence of a favorable attitude. There is a need to develop an effective nationwide burn prevention program and early burn first aid treatment in Saudi Arabia and promote a consistent guideline for burn first aid. 展开更多
关键词 Burn Injury (BI) Burns first Aid Knowledge first Aid Training Jazan City
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Estimation of Landfill Gas and Its Renewable Energy Potential from the Polesgo Controlled Landfill Using First-Order Decay (FOD) Models
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作者 Haro Kayaba Ouarma Issoufou +4 位作者 Dabilgou Téré Compaore Abdoulaye Sanogo Oumar Bere Antoine Koulidiati Jean 《Journal of Environmental Protection》 2024年第10期975-993,共19页
Methane generation in landfills and its inadequate management represent the major avoidable source of anthropogenic methane today. This paper models methane production and the potential resources expected (electrical ... Methane generation in landfills and its inadequate management represent the major avoidable source of anthropogenic methane today. This paper models methane production and the potential resources expected (electrical energy production and potential carbon credits from avoided CH4 emissions) from its proper management in a municipal solid waste landfill located in Ouagadougou, Burkina Faso. The modeling was carried out using two first-order decay (FOD) models (LandGEM V3.02 and SWANA) using parameters evaluated on the basis of the characteristics of the waste admitted to the landfill and weather data for the site. At the same time, production data have been collected since 2016 in order to compare them with the model results. The results obtained from these models were compared to experimental one. For the simulation of methane production, the SWANA model showed better consistency with experimental data, with a coefficient of determination (R²) of 0.59 compared with the LandGEM model, which obtained a coefficient of 0.006. Thus, despite the low correlation values linked to the poor consistency of experimental data, the SWANA model models methane production much better than the LandGEM model. Thus, despite the low correlation values linked to the poor consistency of the experimental data, the SWANA model models methane production much better than the LandGEM V3.02 model. It was noted that the poor consistency of the experimental data justifies these low coefficients, and that they can be improved in the future thanks to ongoing in situ measurements. According to the SWANA model prediction, in 27 years of operation a biogas plant with 33% electrical efficiency using biogas from the Polesgo landfill would avoid 1,340 GgCO2e. Also, the evaluation of revenues due to electricity and carbon credit gave a total revenue derived from methane production of US$27.38 million at a cost of US$10.5/tonne CO2e. 展开更多
关键词 first-Order Decay METHANE Modeling LANDFILL Renewable Energy
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Community Knowledge about Bleeding Control in Jazan, KSA: Is There a Need for First Aid Educational Programs
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作者 Md Mazharul Hoque Hamoud Yahya Alsuriha +10 位作者 Mohamed E. Moukhyer Bahja Siddig Mohamed Mubarak Almaki Amna Moukhyer Fawaz Yahya Masswadi Mofareh Salman Harubi Elias Yosef Modabish Talal Omar Khasawi Yaser Mohammed Hantool Mohammed Awaji Mohammed Madkhali Aziza Mukhayer 《Journal of Biosciences and Medicines》 2024年第6期64-84,共21页
The current study aimed to evaluate the first aid knowledge and general awareness of bleeding control, and their relations with different variables among the population of Jazan City, Saudi Arabia, in 2023. A cross-se... The current study aimed to evaluate the first aid knowledge and general awareness of bleeding control, and their relations with different variables among the population of Jazan City, Saudi Arabia, in 2023. A cross-sectional study was conducted in Jazan City, Saudi Arabia between April 2023 and May 2023. Participants, >13 years old, living in Jazan City, were self-enrolled. Data collection was carried out by distributing a self-reported online survey questionnaire via email and social media apps. A validated, pretested online self-report questionnaire was used for data collection, with data analysis performed using (MS) Excel 2022 and SPSS version 26. A Chi-square test was used to determine the association of sociodemographic variables and Bleeding Control (BC) knowledge with, significance set at p < 0.05. A total of 250 participants completed the questionnaire, predominantly aged between 16 - 25 years, with 152 (60.8%) being male, and about 90% being Saudi citizens. Only 53 (21.2%) participated in previous first aid training concentrating on bleeding control. Only 76 (30.4%) of participants had good knowledge, while 131 (52.4%) exhibited positive attitude towards BC first aid. There were no statistically significant associations between BC knowledge and age, gender, occupation, nationality, and education. However, a significant association was observed between previous BC training and knowledge (Chi-test = 40.373, d.f = 1, p = 0.000) at p < 0.05. Conclusion: The prevalence of poor knowledge of bleeding control among community members in Jazan City was high. The findings of this study should be carefully considered by various healthcare organizations to implement educational first-aid programs and activities aimed at enhancing community awareness and knowledge of bleeding control. 展开更多
关键词 INJURY Uncontrolled Bleeding first Aid Knowledge ATTITUDE Jazan City
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First-Principles Investigation of Charge Transfer Mechanism of B-Doped 3C-SiC Semiconductor Material
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作者 Abdullahi Alkali Dauda Muhammad Yusuf Onimisi +7 位作者 Adeyemi Joshua Owolabi Hameed Adeneyi Lawal Hassan Muhammad Gambo Bashir Mohammed Aliyu Surajo Bala Muhammad Lamido Madugu Muhammad Abdurrahman Nainna Johnson Akinade Bamikole 《World Journal of Condensed Matter Physics》 CAS 2024年第2期35-44,共10页
This study delves into the charge transfer mechanism of boron (B)-doped 3C-SiC through first-principles investigations. We explore the effects of B doping on the electronic properties of 3C-SiC, focusing on a 12.5% im... This study delves into the charge transfer mechanism of boron (B)-doped 3C-SiC through first-principles investigations. We explore the effects of B doping on the electronic properties of 3C-SiC, focusing on a 12.5% impurity concentration. Our comprehensive analysis encompasses structural properties, electronic band structures, and charge density distributions. The optimized lattice constant and band gap energy of 3C-SiC were found to be 4.373 Å and 1.36 eV respectively, which is in agreement with previous research (Bui, 2012;Muchiri et al., 2018). Our results show that B doping narrows the band gap, enhances electrical conductivity, and influences charge transfer interactions. The charge density analysis reveals substantial interactions between B dopants and surrounding carbon atoms. This work not only enhances our understanding of the material’s electronic properties, but also highlights the importance of charge density analysis for characterizing charge transfer mechanisms and their implications in the 3C-SiC semiconductors. 展开更多
关键词 first-Principles Calculations DFT Boron (B)-Doped 3C-SiC Charge Transfer
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A Survey on the Current Situation of Prehospital First Aid about Knowledge, Belief and Behavior among University Students in Jingzhou
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作者 Tianyue Zhang Hong Zhou +1 位作者 Chenyang Xu Juan Zhou 《Open Journal of Applied Sciences》 2024年第5期1251-1261,共11页
Objective: To understand the current situation of prehospital first aid knowledge, attitude and behavior of university students in Jingzhou City. Methods: A prehospital first aid knowledge questionnaire and the conven... Objective: To understand the current situation of prehospital first aid knowledge, attitude and behavior of university students in Jingzhou City. Methods: A prehospital first aid knowledge questionnaire and the convenience sampling method were used to survey 307 university students in Jingzhou City. Results: The mean score of prehospital first aid knowledge of university students in Jingzhou City was 12.85 ± 2.643, the mean score of attitude was 50.73 ± 4.114, and the mean score of behavior was 39.05 ± 8.898;There was a statistically significant difference in the scores of prehospital first aid knowledge, attitude, and behavior of university students depending on whether or not they had received prehospital first aid training (P P Conclusion: Jingzhou University students have a positive attitude toward pre-hospital first aid, but the knowledge level and behavior are low, which suggests that the government, society and the school should create good conditions to promote the improvement of pre-hospital first aid knowledge and ability. 展开更多
关键词 Prehospital first Aid University Student KNOWLEDGE ATTITUDE BEHAVIORS
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Research Progress of Radical Treatment of Helicobacter Pylori Based on Drug Sensitivity Test as First-Line Treatment
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作者 Dong Luo Haidong Zhou +8 位作者 Changtai Luo Wei Wang Luchang Chen Wujia Yang Xianqi Qin Song Huang Wenzhao Zhang Jiahou Xu Jihua Wei 《Journal of Biosciences and Medicines》 2024年第8期30-39,共10页
Helicobacter pylori (HP) infection is a global problem that affects about half of the world’s population and requires sufficient attention in clinical and scientific work. Due to differences in economic and medical c... Helicobacter pylori (HP) infection is a global problem that affects about half of the world’s population and requires sufficient attention in clinical and scientific work. Due to differences in economic and medical conditions among countries around the world, there is currently no unified treatment plan for anti-HP. In China, empirical quadruple therapy is mainly used. With the abuse of antibiotics, many patients face the problem of secondary eradication after failure, and the resistance rate of HP is gradually increasing. After eradication failure, drug sensitivity cultivation is carried out to choose sensitive antibiotics for treatment. A new strategy is currently needed to address how to improve the eradication rate of HP during the first eradication. This article aims to discuss the first-line treatment plans and research progress for eradicating HP based on drug sensitivity testing before eradication. Compared with traditional empirical therapies, treatment based on drug sensitivity results can effectively improve the eradication rate of HP, and reduce drug resistance rates, and adverse reactions, among other benefits. . 展开更多
关键词 Drug Susceptibility Test Helicobacter Pylori (HP) Infection first-Line Treatment HP Culture
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Comparative Studies between Picard’s and Taylor’s Methods of Numerical Solutions of First Ordinary Order Differential Equations Arising from Real-Life Problems
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作者 Khalid Abd Elrazig Awad Alla Elnour 《Journal of Applied Mathematics and Physics》 2024年第3期877-896,共20页
To solve the first-order differential equation derived from the problem of a free-falling object and the problem arising from Newton’s law of cooling, the study compares the numerical solutions obtained from Picard’... To solve the first-order differential equation derived from the problem of a free-falling object and the problem arising from Newton’s law of cooling, the study compares the numerical solutions obtained from Picard’s and Taylor’s series methods. We have carried out a descriptive analysis using the MATLAB software. Picard’s and Taylor’s techniques for deriving numerical solutions are both strong mathematical instruments that behave similarly. All first-order differential equations in standard form that have a constant function on the right-hand side share this similarity. As a result, we can conclude that Taylor’s approach is simpler to use, more effective, and more accurate. We will contrast Rung Kutta and Taylor’s methods in more detail in the following section. 展开更多
关键词 first-Order Differential Equations Picard Method Taylor Series Method Numerical Solutions Numerical Examples MATLAB Software
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A Brief List of "Firsts" for Women in World Politics
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《China Today》 1994年第12期21-21,共1页
The world's first woman president was Isabel Martinez de Peron(b.1931).In July,1974,Juan Domingo Peron,the president of Argentina,died,leaving his wife Isabel Martinez de Peron,then the vice-president,to succeed h... The world's first woman president was Isabel Martinez de Peron(b.1931).In July,1974,Juan Domingo Peron,the president of Argentina,died,leaving his wife Isabel Martinez de Peron,then the vice-president,to succeed him according to the cons stitution. 展开更多
关键词 World for Women in World Politics A Brief List of firsts
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“双一流”背景下资源勘查工程一流专业建设与探索 被引量:2
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作者 高迪 齐永安 +1 位作者 郑德顺 李云波 《高教学刊》 2024年第6期32-35,共4页
随着深入实施科教兴国战略、人才强国战略、创新驱动发展战略,高等教育必然要担当起新的使命和时代重任,而专业建设是高等教育体系的重要支柱,是人才培养的基础平台,资源勘查工程专业关系着我国能源资源安全,为此,在充分分析河南理工大... 随着深入实施科教兴国战略、人才强国战略、创新驱动发展战略,高等教育必然要担当起新的使命和时代重任,而专业建设是高等教育体系的重要支柱,是人才培养的基础平台,资源勘查工程专业关系着我国能源资源安全,为此,在充分分析河南理工大学资源勘查工程专业建设基础上,查找目前存在的问题,对标“一流专业”和“新工科”建设要求,结合河南理工大学特色优势,探索“双一流”背景下资源勘查工程专业的建设路径,总结取得的一些成效,以期进一步促进资源勘查工程专业内涵式发展,同时为我国其他兄弟院校相关专业建设提供借鉴,为实现地球科学强国目标贡献科技和人才力量。 展开更多
关键词 双一流 资源勘查工程专业 国家级一流本科专业建设点 专业建设 新工科
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双一流背景下化学实验中心的建设与实践 被引量:4
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作者 熊辉 高晓莉 +3 位作者 郭雯霁 秦超然 付世涛 龚跃法 《实验室研究与探索》 CAS 北大核心 2024年第1期130-134,共5页
为推动化学实验教学和大型仪器测试平台内涵式并行发展,为教学科研和科普宣传服务,为人才培养服务。根据化学实验中心管理运行情况,探讨了"双一流"背景下院级实验技术平台建设的重要作用,从实验室条件的更新建设、实验教学的... 为推动化学实验教学和大型仪器测试平台内涵式并行发展,为教学科研和科普宣传服务,为人才培养服务。根据化学实验中心管理运行情况,探讨了"双一流"背景下院级实验技术平台建设的重要作用,从实验室条件的更新建设、实验教学的改革实践、大型仪器资源的开放共享等方面介绍了化学实验中心“双一流”建设的经验。依托平台的建设改善师生实验环境,加强实验安全防护,提升教学科研服务质量,推进科普宣传培训力度,培养基础拔尖创新人才。 展开更多
关键词 化学实验中心 双一流建设 实验教学 仪器共享
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The Application of PDCA Circulation Method in Improving the Application of Internet + Smart First Aid in the Treatment of Preoperative Patients with Severe Neurological Diseases
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作者 Liangdan Zhao Shiqi Chen +4 位作者 Chao Wei Ming Zhao Guosen Du Junan Zhou Yubo Huang 《World Journal of Neuroscience》 CAS 2023年第2期91-102,共12页
Objective: To investigate the application and feasibility of PDCA circulation method in the treatment of patients with severe neurological diseases in Internet + smart first aid, with a view to promoting the sustainab... Objective: To investigate the application and feasibility of PDCA circulation method in the treatment of patients with severe neurological diseases in Internet + smart first aid, with a view to promoting the sustainable construction of smart first aid. Methods: A total of 105 patients with severe neurological diseases in Zhuji people’s Hospital and cooperative units were selected, and 52 cases in the research group and 53 cases in the control group were divided according to the single and double number visiting time: In this paper, through reading the literature, the development of Internet + wisdom first aid treatment of patients with severe neurological diseases was investigated, and the common problems were analyzed and summarized, and the research group used the PDCA circulation method to sort out the existing problems, analyze the causes of the problems and improve them. The difference in treatment time between the two groups was compared, and the patient’s satisfaction was evaluated for the time of being transferred to the hospital emergency room by 120 ambulances, the time from emergency admission to surgery (Cath lab), and the satisfaction of the patient. Results: The time from emergency treatment to the operation room (catheter room) in the study group was significantly shortened, and patient satisfaction was significantly improved compared with that in the control group, with a statistically significant difference (P Conclusion: Through the application of PDCA circulation method in the Internet + smart emergency treatment of neurologically severe preoperative patients, the Internet + smart emergency mode can be continuously improved, the treatment process can be significantly optimized, the first aid time can be shortened, and the treatment efficiency of neurocritical ill patients can be improved. Therefore, it has been expected to improve the success rate of treatment and improve the success rate of neurological patients. 展开更多
关键词 PDCA first Aid Mode Quality Management Internet + Smart first Aid
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ITER氦冷固态实验包层模块第一壁氢同位素双向输运数值分析 被引量:1
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作者 王俊 张龙 +2 位作者 王晓宇 武兴华 李茹烟 《核化学与放射化学》 CAS CSCD 北大核心 2024年第2期125-130,I0004,共7页
氦冷固态实验包层模块(HCCB-TBM)安装于国际热核聚变实验堆(ITER)中,用以验证HCCB包层概念的氚增殖能力与热移出能力。HCCB-TBM第一壁用于承受堆芯等离子体粒子轰击和包容内部功能材料。外侧等离子体驱动氘、氚粒子渗透与内侧氢分压驱... 氦冷固态实验包层模块(HCCB-TBM)安装于国际热核聚变实验堆(ITER)中,用以验证HCCB包层概念的氚增殖能力与热移出能力。HCCB-TBM第一壁用于承受堆芯等离子体粒子轰击和包容内部功能材料。外侧等离子体驱动氘、氚粒子渗透与内侧氢分压驱动渗透的同时存在,形成了第一壁的双向氢同位素输运。此双向输运可能对第一壁外表面再循环系数、包层增殖氚的纯化产生重要影响。基于商业软件COMSOL建立第一壁双向氢同位素输运模型,研究第一壁的氢同位素的输运特征。仿真结果表明:第一壁中的冷却剂流道具有强的氢同位素移出能力,使得双向输运解耦合;在ITER等离子体脉冲周期中,放电过程中已扩散到材料内部的氚在等离子体关停时扩散回流到真空室侧,关停时的回流将降低向冷却剂流道的氚渗透损失。 展开更多
关键词 HCCB-TBM 第一壁 氢同位素 双向输运
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习近平文明观的四大鲜明特征 被引量:5
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作者 辛向阳 吕耀龙 《中州学刊》 CSSCI 北大核心 2024年第1期5-12,F0002,共9页
进入新时代以来,伴随中国式现代化进程的持续推进、中华文明自身的不断演化以及中国与世界各民族国家不同文明间交往的日益深入,习近平文明观得以孕育生成。这一文明观,以马克思主义为依据来制定探源中华文明的新标准、认识中华文明的... 进入新时代以来,伴随中国式现代化进程的持续推进、中华文明自身的不断演化以及中国与世界各民族国家不同文明间交往的日益深入,习近平文明观得以孕育生成。这一文明观,以马克思主义为依据来制定探源中华文明的新标准、认识中华文明的突出特性,是马克思主义的文明观;坚持弘扬平等、互鉴、对话、包容的共同价值理念,是胸怀天下的文明观;强调人民是文明创造的主体,以保护人民的人权为文明创造的最终目的,是人民至上的文明观;注重从长时段的历史纵深中认识文明、在世界历史的生成视野中创造文明,是大历史的文明观。这四个方面共同构成习近平文明观的鲜明特征,既体现出中华民族在涵养博大精深中华文明过程中的传承与坚守,又体现出中华民族在对待世界不同文明时的立场与态度。深入理解这四大鲜明特征,对于深刻把握习近平总书记关于中华文明、世界文明以及不同文明之间关系等问题的战略思考和系列论述具有重要意义。 展开更多
关键词 习近平文明观 马克思主义 人民至上
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无机及分析化学一流课程建设的探索与实践 被引量:1
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作者 余凡 李艾华 +4 位作者 刘芸 朱天容 王亮 徐俊晖 王亚珍 《大学化学》 CAS 2024年第8期36-43,共8页
一流课程是人才培养的核心载体,是实现人才培养目标的关键。在“双一流”建设背景下,以江汉大学无机及分析化学省级一流课程为例,探讨了本课程建设的思路和实践。课程从“专业教育和思政教育融合、教学内容与资源整合、线上线下教学方... 一流课程是人才培养的核心载体,是实现人才培养目标的关键。在“双一流”建设背景下,以江汉大学无机及分析化学省级一流课程为例,探讨了本课程建设的思路和实践。课程从“专业教育和思政教育融合、教学内容与资源整合、线上线下教学方式混合”的三个方面开展教学改革,构建了“慕课+翻转课堂+问题导向学习(PBL)”的教学模式及“三段七步”教学法,激发学生学习积极性,培养了学生自主学习能力。相关举措可为地方高校无机及分析化学课程建设提供参考。 展开更多
关键词 一流课程 无机及分析化学 混合式教学
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首发的精神分裂症和抑郁症及双相障碍的治疗延迟(综述) 被引量:1
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作者 周莉 曾如双 +5 位作者 刘肇瑞 黄悦勤 刘晓霞 姜兰 高长青 卢瑾 《中国心理卫生杂志》 CSCD 北大核心 2024年第1期50-54,共5页
本文旨在综述首发的精神分裂症、抑郁症、双相障碍治疗延迟的相关研究,对3类首发精神障碍治疗延迟的影响因素进行比较,发现患者责任感提高、家庭凝聚力降低、病耻感、疾病相关知识匮乏、就医资源匮乏、医疗支持不足会导致治疗延迟,使患... 本文旨在综述首发的精神分裂症、抑郁症、双相障碍治疗延迟的相关研究,对3类首发精神障碍治疗延迟的影响因素进行比较,发现患者责任感提高、家庭凝聚力降低、病耻感、疾病相关知识匮乏、就医资源匮乏、医疗支持不足会导致治疗延迟,使患者病程更长,症状更重,影响其社会功能。 展开更多
关键词 首发 精神分裂症 双相障碍 抑郁症 治疗延迟 综述
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基于育人为先实践为重能力导向理念的病理学课程建设研究 被引量:2
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作者 于丹 高原 +4 位作者 王莹 井欢 潘茜 王哲 刘春英 《中国中医药现代远程教育》 2024年第3期175-177,共3页
当今大学生的创新实践能力培养一直是中国高等教育改革发展的战略主题。辽宁中医药大学病理学教学团队多年来坚持“立德树人、仁者仁心”的教育理念,坚持育人为先、实践为重、能力导向,不断更新教学理念、探索教学方法改革。在课程建设... 当今大学生的创新实践能力培养一直是中国高等教育改革发展的战略主题。辽宁中医药大学病理学教学团队多年来坚持“立德树人、仁者仁心”的教育理念,坚持育人为先、实践为重、能力导向,不断更新教学理念、探索教学方法改革。在课程建设过程中,融合思政教育以提高人文素养,优化课程内容以强化实践能力,开展多元化教学模式以提高综合能力,构建了多元化病理学考核形式。 展开更多
关键词 育人为先 实践为重 能力导向 病理学课程建设 教育教学
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我国体育教育与健康教育融合发展的历程、逻辑与路径 被引量:5
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作者 舒宗礼 王健 夏贵霞 《武汉体育学院学报》 CSSCI 北大核心 2024年第1期75-81,共7页
在国家大力推动全民健身与全民健康深度融合,奋力推进体育强国、教育强国和健康中国建设的时代诉求下,体育教育与健康教育融合发展进入新阶段。采用历史分析法等研究方法,对我国体育教育与健康教育融合发展的历程、特征和逻辑进行梳理... 在国家大力推动全民健身与全民健康深度融合,奋力推进体育强国、教育强国和健康中国建设的时代诉求下,体育教育与健康教育融合发展进入新阶段。采用历史分析法等研究方法,对我国体育教育与健康教育融合发展的历程、特征和逻辑进行梳理与透析,提出现实路径。以新中国成立以来颁布的体育与健康课程标准(体育教学大纲)及其政策实践为线索,发现我国体育教育与健康教育融合发展经历了体育教育与卫生教育结合、体育教育与卫生保健教育结合、体育教育与健康教育内部融合、体育教育与公共健康全面融合四个阶段,且表现出不尽相同的阶段性特征。体育教育与健康教育融合发展具有深刻的理论逻辑、现实逻辑和实践逻辑。当前,我国体育健康教育正处于以公共健康为导向的全面融合发展阶段,需构建并实施以儿童青少年和公共健康为导向,以积极健康的生活方式为核心的中国体育健康教育体系;坚持“健康第一”的指导思想,深化体育健康教育课程改革;落实立德树人根本任务,提供公平而有质量的体育健康教育;加强体育健康教育政策的精准性,提高政策执行力。 展开更多
关键词 体育教育 健康教育 体育健康教育 融合发展 健康第一 立德树人
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贝伐珠单抗联合卡培他滨维持对晚期结肠癌患者预后的影响 被引量:2
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作者 胡丽霞 汪超 《河北医学》 2024年第1期158-163,共6页
目的:探究贝伐珠单抗联合卡培他滨维持对晚期结肠癌患者预后的影响。方法:收集2017年1月至2019年1月期间我院101例晚期结肠癌患者的病例资料,所有患者均接受5-氟尿嘧啶及卡培他滨为基础的贝伐珠单抗联合mFOLFOX6或XELOX化疗一线化疗方案... 目的:探究贝伐珠单抗联合卡培他滨维持对晚期结肠癌患者预后的影响。方法:收集2017年1月至2019年1月期间我院101例晚期结肠癌患者的病例资料,所有患者均接受5-氟尿嘧啶及卡培他滨为基础的贝伐珠单抗联合mFOLFOX6或XELOX化疗一线化疗方案,其中42例患者一线化疗后接受卡培他滨单药维持治疗,纳入对照组,59例患者接受贝伐珠单抗联合卡培他滨维持治疗,纳入观察组,两组治疗均直至病情进展或毒副反应无法耐受。比较两组患者维持治疗时间和疾病控制时间,治疗前后Karnofsky功能状态评分(KPS)、美国东部肿瘤协作组体力状态评分(ZPS),血清肿瘤标志物水平,毒副反应以及远期预后情况。结果:观察组维持治疗时间、疾病控制时间均大于对照组(P<0.05);两组KPS均较治疗前升高,ZPS均较治疗前降低,观察组变化幅度均大于对照组(P<0.05);两组血清癌胚抗原(CEA)、唾液酸化盐藻戊糖(CA199)、胃癌抗原(CA724)水平均较治疗前降低,观察组变化幅度均大于对照组(P<0.05);两组毒副反应发生情况差异无统计学意义(P>0.05);观察组总生存率高于对照组(P<0.05)。结论:晚期结肠癌一线治疗后贝伐珠单抗联合卡培他滨维持治疗安全有效,可延长生存时间,同时不良反应轻微。 展开更多
关键词 晚期结肠癌 一线治疗 贝伐珠单抗 卡培他滨 肿瘤标志物
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首发精神分裂症患者血清sTfR、FGF22水平与临床症状的关系及其诊断价值 被引量:1
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作者 王娟 韩利 +1 位作者 许娇 宋晋 《国际检验医学杂志》 CAS 2024年第2期224-228,共5页
目的探讨首发精神分裂症(FES)患者血清可溶性转铁蛋白受体(sTfR)及成纤维细胞生长因子22(FGF22)表达情况,分析二者与FES患者临床症状的关系并进行诊断价值分析。方法选取2021年3月至2023年2月在该院确诊的97例FES患者作为FES组,同期选... 目的探讨首发精神分裂症(FES)患者血清可溶性转铁蛋白受体(sTfR)及成纤维细胞生长因子22(FGF22)表达情况,分析二者与FES患者临床症状的关系并进行诊断价值分析。方法选取2021年3月至2023年2月在该院确诊的97例FES患者作为FES组,同期选取来该院体检的96例健康志愿者作为对照组。采用免疫透射比浊法检测sTfR水平,酶联免疫吸附试验(ELISA)检测FGF22水平,Spearman法分析FES患者血清中sTfR及FGF22水平与阳性与阴性病症量表(PANSS)评分及威斯康辛卡片分类测验(WCST)结果的相关性,受试者工作特征(ROC)曲线分析sTfR及FGF22水平对FES的临床诊断价值。结果两组在性别、年龄、体质量指数、受教育年限、饮酒史及吸烟史方面差异均无统计学意义(P>0.05),与对照组比较,FES组血清sTfR及FGF22水平均下降(P<0.05)。sTfR单独诊断FES的曲线下面积(AUC)为0.835,最佳截断值为4.606 mg/L,FGF22单独诊断FES的AUC为0.772,最佳截断值为208.333μg/L,二者联合诊断的AUC(0.921)大于sTfR单独诊断的AUC(Z=2.613,P=0.009)及FGF22单独诊断的AUC(Z=5.140,P<0.001);sTfR高水平组及FGF22高水平组的PANSS阳性症状评分、阴性症状评分、病理症状评分、总评分、WCST持续性错误数、错误应答数分别低于sTfR低水平组及FGF22低水平组(P<0.05),而WCST完成分类数、WCST正确应答数分别高于sTfR低水平组及FGF22低水平组(P<0.05);FES组中sTfR、FGF22水平与PANSS阳性症状评分、阴性症状评分、病理症状评分、总评分、WCST持续性错误数、WCST错误应答数均呈负相关(P<0.05),与WCST完成分类数及WCST正确应答数均呈正相关(P<0.05)。结论FES患者血清sTfR及FGF22水平下降,联合检测sTfR及FGF22水平对于FES的临床诊断具有重要意义。 展开更多
关键词 首发精神分裂症 可溶性转铁蛋白受体 成纤维细胞生长因子22
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