The renowned translator Yang Yi passed away in 2023.Many scholars argue that,influenced by their biological gender,female translators often employ translation methods in adherence to feminist translation or reflect ch...The renowned translator Yang Yi passed away in 2023.Many scholars argue that,influenced by their biological gender,female translators often employ translation methods in adherence to feminist translation or reflect characteristics typical of female translators.This study examines the translation of Wuthering Heights by Yang Yi,focusing on whether there is a definite influence of gender on translator behavior.While existing literature primarily analyzes Yang Yi’s work through a feminist lens,this research takes a broader approach.By considering the translator’s social background and translation practice,this paper challenges the assumption that her work strictly aligns with feminist translation theories.Instead,this study emphasizes the importance of considering diverse factors when interpreting translated works,moving beyond a singular gender-based standpoint.展开更多
AIM To observe the changes in oxygen free radical (OFR) and the curative effect of traditional Chinese medicine 'Qing Yi Tang' in acute necrotizing pancreatitis (ANP).METHODS After induction of ANP by injectio...AIM To observe the changes in oxygen free radical (OFR) and the curative effect of traditional Chinese medicine 'Qing Yi Tang' in acute necrotizing pancreatitis (ANP).METHODS After induction of ANP by injection of sodium taurocholate into pancreatic duct, 16 dogs were randomly divided into control group and Chinese medicine group. Serum amylase, SOD and MDA were determined on postoperative day 1, 2, 4 and 7. The animals were sacrificed on day 7. SOD and MDA in organs were determined, and pathological changes in pancreas were observed.RESULTS As compared with control group, the serum level of amylase (734U/L vs 2783U/L) and MDA (7.8nmol/ml vs 14.8nmol/ml) in Chinese medicine group were decreased on day 7 (P＜0.05), while SOD increased significantly (281nU/ml vs 55nU/ml, P＜0.01), and similar changes occurred in MDA and SOD in organs, especially in the pancreas; the pathological changes in the pancreas were alleviated as well.CONCLUSION 'Qing Yi Tang' is effective in clearing OFRs and alleviating pathological changes in ANP.展开更多
In the industrial targeted poverty alleviation,land circulation is a key process. Based on the national strategy of targeted poverty alleviation,this paper combined the industrial development of targeted poverty allev...In the industrial targeted poverty alleviation,land circulation is a key process. Based on the national strategy of targeted poverty alleviation,this paper combined the industrial development of targeted poverty alleviation with land circulation. According to the field survey on the current situation of land circulation and promotion of the industrial poverty alleviation in the typical project area of Zhongping Village in Zhongping Town and Jiaowuying Village in Jiulong Town in Luquan Yi and Miao Autonomous County in Yunnan Province,located in the high mountain canyon area of Jinsha River in the upper reaches of the Yangtze River in the west of China. This paper summarized and analyzed the organization and operation mechanism,basic practices and main results of the land circulation and promotion of industrial poverty alleviation model in the typical project area of the county. It also summarized the innovation and successful experience of the model,and then came up with measures to further promote the implementation of the model,so as to provide necessary reference for the implementation of land circulation and industrial targeted poverty alleviation for the poverty-stricken counties in Yunnan Province and similar provinces( cities,regions).展开更多
A study of the genetic diversity within four subpopulations of Chimonobambusa rivularis Yi and adaptations to altitude, habitat and related factors in Qionglai City of Sichuan province in China, analyzed by random amp...A study of the genetic diversity within four subpopulations of Chimonobambusa rivularis Yi and adaptations to altitude, habitat and related factors in Qionglai City of Sichuan province in China, analyzed by random amplified polymorphic DNA technique. 22 random primers were selected in the amplification and 375 repetitive loci with 350 polymorphic loci were produced. The total average percentage of amplification loci was 93.3%. The genetic diversity of every subpopulation was medium on （the percentage of amplification loci was 49.33%-66.67%）. The genetic diversity of high altitude samples of Zhengtiantai was lower than that of low altitude Wutonggang＇s. There was no obvious differentiation between two subpopulations of Zhengtiantais. The correlation is very low between altitude and the amplification loci and the genetic distance, Pearson correlation coefficient was 0.431 and 0.488 （P 〈 0.01）. Through investigation, the primary cause of heredity multiplicity drops was that the habitat had been destroyed by tourism development and other human disturbance.展开更多
The research reviewed connotation, characteristics and significance of urban-rural eco-village and concluded approaches to eco-village planning from site selection, function division, environment and product selection...The research reviewed connotation, characteristics and significance of urban-rural eco-village and concluded approaches to eco-village planning from site selection, function division, environment and product selection. Finally, a case study of Hongbao Hundred-fruit Eco-village was introduced.展开更多
Objective To assess the effects of Yi Qi Jie Du Decoction(YQJDD)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying mechanism.Methods NPC-SCs were collected in serum-free culture system and i...Objective To assess the effects of Yi Qi Jie Du Decoction(YQJDD)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying mechanism.Methods NPC-SCs were collected in serum-free culture system and identified by the sphere formation assay.The effect of YQJDD on the proliferation of NPC-SCs was detected using the Cell Counting Kit-8 assay.The change of mitochondrial membrane potential(ΔΨm)in NPC-SCs following treatment with YQJDD was investigated by JC-1 staining.The levels of apoptosisassociated proteins were examined using western blot analysis.Results YQJDD significantly inhibited the proliferation of NPCSCs in dose-and time-dependent manners.JC-1 staining revealed that YQJDD lowered theΔΨm of NPC-SCs in a timedependent manner.After treatment with YQJDD,the expression of cleaved caspase-3,-7 and-9,cleaved poly-ADP ribose polymerase,P21 and P53 were increased,while the expression of Survivin in NPC-SCs was decreased.However,the expression of cleaved caspase-8 remained nearly unchanged.Conclusions YQJDD inhibits the growth and induces apoptosis of NPC-SCs via an intrinsic apoptosis pathway.展开更多
Objective To assess the effects of Yi Qi Jie Du Formula(YQJDF)combined with salinomycin(SAL)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying molecular mechanisms.Methods Cell counting meth...Objective To assess the effects of Yi Qi Jie Du Formula(YQJDF)combined with salinomycin(SAL)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying molecular mechanisms.Methods Cell counting methods,the CCK-8 assay,transwell migration assay and JC-1 staining,were used to observe the effects of the combination on the proliferation,migration and apoptosis of NPC stem cells,respectively.Western blot was used to detect the levels of protein in NPC-SCs.Results YQJDF combined with SAL had a synergistic effect on the inhibition of proliferation and migration and induction of NPCSC apoptosis.Mechanistically,YQJDF combined with SAL synergistically upregulated the levels of apoptotic proteins,including cleaved Caspase-3,cleaved Caspase-7 and cleaved Caspase-9.Moreover,YQJDF combined with SAL synergistically decreased the levels of CD44,p-c-Src,Ras,p-PKCδ,p-MEK,p-c-Raf,p-ERK1/2 and p-AKT proteins.Conclusions The combination of YQJDF and SAL has a synergistic effect on the inhibition of NPC-SC proliferation and migration and induction of apoptosis,which may be closely related to the downregulation of the CD44/Ras signaling pathway.展开更多
Objective: To explore changes of neural stem cells (NSCs) following intracerebral hemorrhage (ICH) and the effect of Nao Yi-an granule (脑溢安颗粒, NYA) on them, and furthermore, to explore NYA's therapeutic mecha...Objective: To explore changes of neural stem cells (NSCs) following intracerebral hemorrhage (ICH) and the effect of Nao Yi-an granule (脑溢安颗粒, NYA) on them, and furthermore, to explore NYA's therapeutic mechanism Methods: Sixty rats were randomly divided into three groups, the sham operation control group, the ICH group and the NYA-treated group. Except those in the sham operation control group, all other rats were replicated to ICH models by stereotactical injection of collagenase type Ⅶ into their globus pallidus. After modeling, the rats in the NYA-treated group were administered with NYA at the dosage of 4. 92 g·kg-1·d-1 by gastrogavage, while those in the other two groups, 4 ml distilled water were given instead. The behavioral test was used to evaluate neurological deficit and immunohistochemical method was used to detect Nestin expression, the special marker for neural stem cells. Results: The ICH animals showed notable placing deficit in forlimbs from day 1 to day 28 after modeling. The deficit in the NYA-treated group was similar to that of the ICH group, but the former got recovered better than the latter from day 21 to 28, with significant difference shown ( P<0.05). Nestin-positive cells (N+ cells) could be seen around the hemotoma from day 2 on in the ICH group, the number of which gradually increased from day 4 to 7 ( P< 0.01) and reached the peak on day 14 (P<0.05), but reduced significantly on day 28 (P<0.01). Compared with that of the ICH group at the same time points , there was no significant difference in number of N+ cells in the NYA group on day 2 and 4, but it reached the peak earlier on day 7(P<0.01),with the level significantly higher than that in the ICH group( P<0. 01), and this high level lasted to day 14. Conclusion: NYA could promote the recovery of behavioral deficit in collagenase type Ⅶ-induced ICH rats, and increase the number of nestin-immunoreactive NSCs, suggesting that its effect on NSCs may be one of its pharmaceutical mechanisms in treating ICH.展开更多
文摘The renowned translator Yang Yi passed away in 2023.Many scholars argue that,influenced by their biological gender,female translators often employ translation methods in adherence to feminist translation or reflect characteristics typical of female translators.This study examines the translation of Wuthering Heights by Yang Yi,focusing on whether there is a definite influence of gender on translator behavior.While existing literature primarily analyzes Yang Yi’s work through a feminist lens,this research takes a broader approach.By considering the translator’s social background and translation practice,this paper challenges the assumption that her work strictly aligns with feminist translation theories.Instead,this study emphasizes the importance of considering diverse factors when interpreting translated works,moving beyond a singular gender-based standpoint.
文摘AIM To observe the changes in oxygen free radical (OFR) and the curative effect of traditional Chinese medicine 'Qing Yi Tang' in acute necrotizing pancreatitis (ANP).METHODS After induction of ANP by injection of sodium taurocholate into pancreatic duct, 16 dogs were randomly divided into control group and Chinese medicine group. Serum amylase, SOD and MDA were determined on postoperative day 1, 2, 4 and 7. The animals were sacrificed on day 7. SOD and MDA in organs were determined, and pathological changes in pancreas were observed.RESULTS As compared with control group, the serum level of amylase (734U/L vs 2783U/L) and MDA (7.8nmol/ml vs 14.8nmol/ml) in Chinese medicine group were decreased on day 7 (P＜0.05), while SOD increased significantly (281nU/ml vs 55nU/ml, P＜0.01), and similar changes occurred in MDA and SOD in organs, especially in the pancreas; the pathological changes in the pancreas were alleviated as well.CONCLUSION 'Qing Yi Tang' is effective in clearing OFRs and alleviating pathological changes in ANP.
基金Supported by Project of Office of Rural Work Leading Group of Kunming Municipal Committee of the Communist Party of China"Study on the Poverty Alleviation Model of Kunming City in the Context of World Poverty Reduction"Postgraduate Project of Scientific Research Foundation of Yunnan Provincial Department of Education(2018Y112)"Study on Promotion of Industrial Targeted Poverty Alleviation through Land Circulation in Typical Poverty-stricken Counties in Yunnan Province"Construction Project of Party Branch Secretary's studio of"Double Leader"Teachers in Colleges and Universities of the Ministry of Education of China
文摘In the industrial targeted poverty alleviation,land circulation is a key process. Based on the national strategy of targeted poverty alleviation,this paper combined the industrial development of targeted poverty alleviation with land circulation. According to the field survey on the current situation of land circulation and promotion of the industrial poverty alleviation in the typical project area of Zhongping Village in Zhongping Town and Jiaowuying Village in Jiulong Town in Luquan Yi and Miao Autonomous County in Yunnan Province,located in the high mountain canyon area of Jinsha River in the upper reaches of the Yangtze River in the west of China. This paper summarized and analyzed the organization and operation mechanism,basic practices and main results of the land circulation and promotion of industrial poverty alleviation model in the typical project area of the county. It also summarized the innovation and successful experience of the model,and then came up with measures to further promote the implementation of the model,so as to provide necessary reference for the implementation of land circulation and industrial targeted poverty alleviation for the poverty-stricken counties in Yunnan Province and similar provinces( cities,regions).
文摘A study of the genetic diversity within four subpopulations of Chimonobambusa rivularis Yi and adaptations to altitude, habitat and related factors in Qionglai City of Sichuan province in China, analyzed by random amplified polymorphic DNA technique. 22 random primers were selected in the amplification and 375 repetitive loci with 350 polymorphic loci were produced. The total average percentage of amplification loci was 93.3%. The genetic diversity of every subpopulation was medium on （the percentage of amplification loci was 49.33%-66.67%）. The genetic diversity of high altitude samples of Zhengtiantai was lower than that of low altitude Wutonggang＇s. There was no obvious differentiation between two subpopulations of Zhengtiantais. The correlation is very low between altitude and the amplification loci and the genetic distance, Pearson correlation coefficient was 0.431 and 0.488 （P 〈 0.01）. Through investigation, the primary cause of heredity multiplicity drops was that the habitat had been destroyed by tourism development and other human disturbance.
文摘The research reviewed connotation, characteristics and significance of urban-rural eco-village and concluded approaches to eco-village planning from site selection, function division, environment and product selection. Finally, a case study of Hongbao Hundred-fruit Eco-village was introduced.
基金funding support from the National Natural Science Foundation of China (No. 81573721, No. 81874408 and No. 81973914)the Natural Science Foundation of Hunan (No. 2017JJ3246 and No. 2019JJ40216)Excellent Youth Fund of Hunan Provincial Education Department (No. 19B439)
文摘Objective To assess the effects of Yi Qi Jie Du Decoction(YQJDD)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying mechanism.Methods NPC-SCs were collected in serum-free culture system and identified by the sphere formation assay.The effect of YQJDD on the proliferation of NPC-SCs was detected using the Cell Counting Kit-8 assay.The change of mitochondrial membrane potential(ΔΨm)in NPC-SCs following treatment with YQJDD was investigated by JC-1 staining.The levels of apoptosisassociated proteins were examined using western blot analysis.Results YQJDD significantly inhibited the proliferation of NPCSCs in dose-and time-dependent manners.JC-1 staining revealed that YQJDD lowered theΔΨm of NPC-SCs in a timedependent manner.After treatment with YQJDD,the expression of cleaved caspase-3,-7 and-9,cleaved poly-ADP ribose polymerase,P21 and P53 were increased,while the expression of Survivin in NPC-SCs was decreased.However,the expression of cleaved caspase-8 remained nearly unchanged.Conclusions YQJDD inhibits the growth and induces apoptosis of NPC-SCs via an intrinsic apoptosis pathway.
基金We thank for the funding support from the National Natural Science Foundation of China(No.81874408,No.81973914 and No.81573721)the Natural Science Foundation of Hunan Province,China(No.2019JJ40216)Study Fundation of Hunan Provincial Education Department(No.19B439).
文摘Objective To assess the effects of Yi Qi Jie Du Formula(YQJDF)combined with salinomycin(SAL)on nasopharyngeal carcinoma stem cells(NPC-SCs)and investigate the underlying molecular mechanisms.Methods Cell counting methods,the CCK-8 assay,transwell migration assay and JC-1 staining,were used to observe the effects of the combination on the proliferation,migration and apoptosis of NPC stem cells,respectively.Western blot was used to detect the levels of protein in NPC-SCs.Results YQJDF combined with SAL had a synergistic effect on the inhibition of proliferation and migration and induction of NPCSC apoptosis.Mechanistically,YQJDF combined with SAL synergistically upregulated the levels of apoptotic proteins,including cleaved Caspase-3,cleaved Caspase-7 and cleaved Caspase-9.Moreover,YQJDF combined with SAL synergistically decreased the levels of CD44,p-c-Src,Ras,p-PKCδ,p-MEK,p-c-Raf,p-ERK1/2 and p-AKT proteins.Conclusions The combination of YQJDF and SAL has a synergistic effect on the inhibition of NPC-SC proliferation and migration and induction of apoptosis,which may be closely related to the downregulation of the CD44/Ras signaling pathway.
文摘Objective: To explore changes of neural stem cells (NSCs) following intracerebral hemorrhage (ICH) and the effect of Nao Yi-an granule (脑溢安颗粒, NYA) on them, and furthermore, to explore NYA's therapeutic mechanism Methods: Sixty rats were randomly divided into three groups, the sham operation control group, the ICH group and the NYA-treated group. Except those in the sham operation control group, all other rats were replicated to ICH models by stereotactical injection of collagenase type Ⅶ into their globus pallidus. After modeling, the rats in the NYA-treated group were administered with NYA at the dosage of 4. 92 g·kg-1·d-1 by gastrogavage, while those in the other two groups, 4 ml distilled water were given instead. The behavioral test was used to evaluate neurological deficit and immunohistochemical method was used to detect Nestin expression, the special marker for neural stem cells. Results: The ICH animals showed notable placing deficit in forlimbs from day 1 to day 28 after modeling. The deficit in the NYA-treated group was similar to that of the ICH group, but the former got recovered better than the latter from day 21 to 28, with significant difference shown ( P<0.05). Nestin-positive cells (N+ cells) could be seen around the hemotoma from day 2 on in the ICH group, the number of which gradually increased from day 4 to 7 ( P< 0.01) and reached the peak on day 14 (P<0.05), but reduced significantly on day 28 (P<0.01). Compared with that of the ICH group at the same time points , there was no significant difference in number of N+ cells in the NYA group on day 2 and 4, but it reached the peak earlier on day 7(P<0.01),with the level significantly higher than that in the ICH group( P<0. 01), and this high level lasted to day 14. Conclusion: NYA could promote the recovery of behavioral deficit in collagenase type Ⅶ-induced ICH rats, and increase the number of nestin-immunoreactive NSCs, suggesting that its effect on NSCs may be one of its pharmaceutical mechanisms in treating ICH.
