近年来,业务流程的精确管理受到越来越多的关注,作为业务流程管理内容之一的一致性检查技术正变得越来越重要。现有的一致性检查技术主要从模型的控制流角度出发,并未考虑业务流程中的数据或数据的变化对业务流程产生的影响,为此提出了...近年来,业务流程的精确管理受到越来越多的关注,作为业务流程管理内容之一的一致性检查技术正变得越来越重要。现有的一致性检查技术主要从模型的控制流角度出发,并未考虑业务流程中的数据或数据的变化对业务流程产生的影响,为此提出了一种基于数据影响的业务流程一致性检查方法。首先,通过业务流程建模符号(business process modeling notation,BPMN)模型中数据和行为之间的依赖关系来分析数据对偏差活动预期行为的影响,进而获取偏差活动的预期行为集;其次,通过在BPMN模型中引入决策模型和符号(decision model and notation,DMN)决策表来充分捕获当前实例执行的数据上下文与行为上下文之间的关系,以区分有效数据更改和异常数据更改,找到偏差活动的有效预期行为集。最后,通过设计数据对偏差活动影响的各类成本函数提出了有效一致性检查方法。实验结果表明,相比已有工作,该方法在进行业务流程一致性检查时提高了业务流程的一致性,可以成功捕获偏差活动作出反应的适应行为,使得业务流程在复杂多变的环境下表现得更加准确、合理。展开更多
[ Objectives ] This study was conducted to evaluate the action of the aqueous extract of a medicinal plant Plumbago zeylanica L. in the reversal of dime- thylnitrosamine （DMN） -induced hepatic fibrosis in rats, and ...[ Objectives ] This study was conducted to evaluate the action of the aqueous extract of a medicinal plant Plumbago zeylanica L. in the reversal of dime- thylnitrosamine （DMN） -induced hepatic fibrosis in rats, and to provide a scientific basis for the utilization of P. zeylanica in treatment of hepatic fibrosis. [Meth- ods ] Hepatic fibrosis in rats was induced by intraperitoneal injection of DMN. The rats were then given the aqueous extract of P. zeylanica at high, medium or low concentration by garage for five weeks. Serum level of alanine aminotransferase （ALT） was determined by lactate dehydrogenase （LDH）-release assay, and serum level of aspartate transaminase （AST） was measured by UV-malate dehydrogenase （MDH） assay. Serum levels of total bilirubin （TBIL）, direct bilirubin （DBIL） and indirect bilirubin （1BIL） were measured by vanadate oxidation assay. Four indices of hepatic fibrosis （hyaluronic acid, laminin, procollagen type III and colla- gen type IV） were determined by radioimmunoassay （RIA） assay. Morphological damage of liver tissue was observed by hematoxylin-eosin staining （H＆E stai- ning）. Immunohistochemical staining was performed to determine the location and area of deposited collagen type I, collagen type III and ct-smeoth muscle actin （a-SMA） in liver tissue. [ Results] Compared with the negative control （rats with diseased fiver and untreated with P. zeylanica aqueous extract）, the serum lev- els of ALT, AST, TBIL, DBIL and IBIL were significantly decreased by P. zeylanica aqueous extract; the levels of the four serum indices of hepatic fibrosis were also obviously reduced. H＆E staining showed that hepatic fibrosis in rats was obviously inhibited or even reversed by P. zeylanica aqueous extract. Immunohisto- chemical staining proved that the aqueous extract of P. zeylanica significantly reduced the area and coloration of collagen type I, collagen type III and ct-SMA in rat liver. [ Conclusions] The aqueous extract of P. zeylanica has a definite effect in reversal of DMN-indueed hepatic fibrosis in rat by promoting the recovery of liver function, reversal of histopathological changes and reducing fibrotic collagen.展开更多
综述马尔科夫随机场(Markov Random Field,MRF)的研究和应用历史,着重讨论了图像分割中MRF的原理和应用。分析了可分解马尔科夫网(Decomposable Markov Networks,DMN)的一般方法以及DMN在图像分割问题中的应用。比较研究了MRF和DMN的区...综述马尔科夫随机场(Markov Random Field,MRF)的研究和应用历史,着重讨论了图像分割中MRF的原理和应用。分析了可分解马尔科夫网(Decomposable Markov Networks,DMN)的一般方法以及DMN在图像分割问题中的应用。比较研究了MRF和DMN的区别和联系。展开更多
文摘近年来,业务流程的精确管理受到越来越多的关注,作为业务流程管理内容之一的一致性检查技术正变得越来越重要。现有的一致性检查技术主要从模型的控制流角度出发,并未考虑业务流程中的数据或数据的变化对业务流程产生的影响,为此提出了一种基于数据影响的业务流程一致性检查方法。首先,通过业务流程建模符号(business process modeling notation,BPMN)模型中数据和行为之间的依赖关系来分析数据对偏差活动预期行为的影响,进而获取偏差活动的预期行为集;其次,通过在BPMN模型中引入决策模型和符号(decision model and notation,DMN)决策表来充分捕获当前实例执行的数据上下文与行为上下文之间的关系,以区分有效数据更改和异常数据更改,找到偏差活动的有效预期行为集。最后,通过设计数据对偏差活动影响的各类成本函数提出了有效一致性检查方法。实验结果表明,相比已有工作,该方法在进行业务流程一致性检查时提高了业务流程的一致性,可以成功捕获偏差活动作出反应的适应行为,使得业务流程在复杂多变的环境下表现得更加准确、合理。
基金Supported by National Natural Science Foundation of China(81403189,81460628,81660705,81560690)Scientific Research Project for Higher Education of Guangxi Zhuang Autonomous Region Education Department(YB2014182)
文摘[ Objectives ] This study was conducted to evaluate the action of the aqueous extract of a medicinal plant Plumbago zeylanica L. in the reversal of dime- thylnitrosamine （DMN） -induced hepatic fibrosis in rats, and to provide a scientific basis for the utilization of P. zeylanica in treatment of hepatic fibrosis. [Meth- ods ] Hepatic fibrosis in rats was induced by intraperitoneal injection of DMN. The rats were then given the aqueous extract of P. zeylanica at high, medium or low concentration by garage for five weeks. Serum level of alanine aminotransferase （ALT） was determined by lactate dehydrogenase （LDH）-release assay, and serum level of aspartate transaminase （AST） was measured by UV-malate dehydrogenase （MDH） assay. Serum levels of total bilirubin （TBIL）, direct bilirubin （DBIL） and indirect bilirubin （1BIL） were measured by vanadate oxidation assay. Four indices of hepatic fibrosis （hyaluronic acid, laminin, procollagen type III and colla- gen type IV） were determined by radioimmunoassay （RIA） assay. Morphological damage of liver tissue was observed by hematoxylin-eosin staining （H＆E stai- ning）. Immunohistochemical staining was performed to determine the location and area of deposited collagen type I, collagen type III and ct-smeoth muscle actin （a-SMA） in liver tissue. [ Results] Compared with the negative control （rats with diseased fiver and untreated with P. zeylanica aqueous extract）, the serum lev- els of ALT, AST, TBIL, DBIL and IBIL were significantly decreased by P. zeylanica aqueous extract; the levels of the four serum indices of hepatic fibrosis were also obviously reduced. H＆E staining showed that hepatic fibrosis in rats was obviously inhibited or even reversed by P. zeylanica aqueous extract. Immunohisto- chemical staining proved that the aqueous extract of P. zeylanica significantly reduced the area and coloration of collagen type I, collagen type III and ct-SMA in rat liver. [ Conclusions] The aqueous extract of P. zeylanica has a definite effect in reversal of DMN-indueed hepatic fibrosis in rat by promoting the recovery of liver function, reversal of histopathological changes and reducing fibrotic collagen.
文摘综述马尔科夫随机场(Markov Random Field,MRF)的研究和应用历史,着重讨论了图像分割中MRF的原理和应用。分析了可分解马尔科夫网(Decomposable Markov Networks,DMN)的一般方法以及DMN在图像分割问题中的应用。比较研究了MRF和DMN的区别和联系。
