Study on Strategies for Methane Injection in a DISI （Direct Injection Spark Ignition） Engine

This paper deals with the application of two different injection strategies in a natural gas direct injection spark ignition single-cylinder engine model. The analysis includes the air flow characterization during compression stroke and also the charge stratification. Two different swirl ratios are applied and piston bowl effects are analyzed during the gas jet deflection towards the spark plug. Achieving wall-guided effect, consequently, the charge stratification in spark plug region is obtained. The goal is to study the mixture formation differences for a single and a bi pulsed CNG （compressed natural gas） injection profiles and check the evolution of the methane concentration at the spark plug at the start of combustion.

Neonatal Direct Rigid Laryngoscopy and Bronchoscopy: A Near Miss

Airway management is a skill necessary for healthcare providers who manage patients. Intubation is a skill that both anesthesiologists and intensivists use daily. We present a case of a neonate that developed significant worsening stridor after a successful intubation for a hernia repair. After 4 intubation attempts, with easy visualization of the vocal cords and unsuccessful placement of the endotracheal tube, the patient was emergently brought to the operating room for evaluation.

“Flow” Transcranial Direct Current Stimulation (tDCS) for Depression Treatment in a Primary Healthcare General Practice—An Open-Label Cohort Study Measuring Montgomery-Åsberg Depression Rating Scale (MADRS-S) Outcomes

Background: Flow FL-100 is a transcranial direct current stimulation (tDCS) device self-administered by a patient at home in combination with a software application delivered wellbeing behaviour therapy training. tDCS has evidence of effectiveness in treating symptoms of depression. Purpose/Aim: This post marketing study evaluated the effect of Flow on depression for primary care general practice patients with depression symptoms. Methods: Open-label patient cohort design with no control group. Inclusion criteria were aged 18 years or over and reporting depression symptoms. Participants self-administered five 30 minute tDCS sessions per week for the first three weeks, and then 3 sessions per week following this. Three, six and ten week assessment with participant self-report measure: Montgomery- Åsberg Depression Rating Scale (MADRS-S). Results: MADRS-S remission rates were between 29% - 30% at three weeks, 33% - 34% at six-weeks and 50% at 10-weeks treatment. There was a significant improvement in MADRS-S with large effect sizes at all time points. Conclusions: Flow tDCS can be delivered through a primary healthcare general practice service and patients will choose to use. Flow tDCS provides an effective depression treatment in addition and as an alternative to antidepressants and psychotherapy. tDCS has evidence as an effective depression treatment, and the widespread availability of tDCS in primary care general practice should be considered.

Unraveling the Impact of Direct-Acting Antivirals on Hepatitis-Linked Cirrhosis: A Comprehensive Analysis of Fibrosis, Child Score, and Disease Progression

The treatment of hepatitis C has undergone a significant boom since the advent of direct acting antivirals (DAA). Indeed, the interferon-ribavirin combination that has been used to treat hepatitis C has a virological response in only 45% of cases with significant side effects. The advent of direct-acting antivirals has changed the prognosis of cirrhotic patients with hepatitis C. DAAs have ensured a sustained viral response in the majority of patients. Our work aims to see the evolution of hepatitis C patients at the cirrhosis stage under DAA. We conducted a retrospective study over 15 years (January 2009, January 2024) including all patients with post-viral cirrhosis C, whom we divided into two groups: group A, cirrhotic patients who received ribavirin and interferon, and group B, patients on DAA. From January 2009 to January 2024, we conducted a study of 182 patients with viral hepatitis C, including 102 cirrhotic patients. The mean age was 55 years. 66% of patients were initially treated with the ribavirin interferon combination, while 34% received direct-acting antivirals (DAAs). Since the introduction of DAAs, the most commonly used regimens have been sofosbuvir/daclatasvir with or without ribavirin and sofosbuvir/ledipasvir with or without ribavirin. Group A achieved sustained virological response (SVR) in 60% of cases, with notable side effects. In Group B, SVR was 98.18%, with improved tolerability and fewer side effects than previous treatments. Fifteen patients developed hepatocellular carcinoma (HCC), with a significantly lower mortality rate in those treated with DAAs compared with pegylated dual therapy (p: 0.001).

Transcranial Direct Current Stimulation: Effects on Motor and Non-Motor Symptoms of Parkinson’s Disease

Introduction: In the last thirty years, brain neuromodulation techniques have been used as an alternative to pharmacological treatment of neurological disorders. Parkinson’s disease (PD) is a neurodegenerative disorder leading to bradykinesia, rest tremor, postural changes, and non-motor symptoms such as depression, anxiety, sleep disorders, pain, and cognitive decline that compromises executive functions (EFs), responsible for the orderly execution of behaviors and tasks of daily life and intentional and directed actions. To this date, a few studies with transcranial direct current stimulation (tDCS) have shown beneficial effects in PD patients concerning specific motor and non-motor symptoms, targeting the motor cortex and/or prefrontal regions. Objective: The main objective of this study was to evaluate the effects of left prefrontal tDCS across a broad spectrum of motor and non-motor symptoms of PD using established validated scales. Method: Single-blind randomized clinical trial with 18 volunteers with PD, aged between 45 and 80 years (66.1 ± 9.65), who met inclusion and exclusion criteria. Participants were submitted to assessments of motor and non-motor functions employing psychometric scales and tests to evaluate EFs and were randomly divided into two groups: control (sham stimulation) and experimental (active stimulation). All participants were involved in three separate tDCS sessions. The anode was positioned over the left dorsolateral prefrontal cortex and the cathode over the right supraorbital region, with a direct current intensity of 2 mA, lasting 20 minutes. At the end of the three sessions, all participants were reassessed. Results: Significant effects of tDCS on non-motor functions were observed for cognition (verbal fluency of actions, clock copy test, appointment by visual confrontation, and verbal memory with immediate free recall) and subjective assessment of sleep quality (overall restlessness and discomfort in the arms and legs at night, leg and arm cramps at night and distressing dreams). There was also an improvement in the rate of errors and successes for congruent and incongruent stimuli of the Stroop Test. The beneficial effects on motor function were decreased rigidity, improved gait, and greater agility in the finger-tapping test. Conclusion: Three tDCS sessions showed positive results for participants with PD, producing significant improvements in various motor and non-motor functions, including sleep quality, cognition, and EFs. Additionally, the present results indicate that tDCS neuromodulation of the left dorsolateral prefrontal cortex region is feasible, safe, and provides significant objective benefits for PD patients.

Positive Effect of Transcranial Direct Current Stimulation on Visual Verbal Working Memory in Patients with Attention-Deficit/Hyperactivity Disorder

Background: Working memory is an executive function that plays an important role in many aspects of daily life, and its impairment in patients with attention-deficit/hyperactivity disorder (ADHD) affects quality of life. The dorsolateral prefrontal cortex (DLPFC) has been a good target site for transcranial direct current stimulation (tDCS) due to its intense involvement in working memory. In our 2018 study, tDCS improved visual-verbal working memory in healthy subjects. Objective: This study examines the effects of tDCS on ADHD patients, particularly on verbal working memory. Methods: We conducted an experiment involving verbal working memory of two modalities, visual and auditory, and a sustained attention task that could affect working memory in 9 ADHD patients. Active or sham tDCS was applied to the left DLPFC in a single-blind crossover design. Results: tDCS significantly improved the accuracy of visual-verbal working memory. In contrast, tDCS did not affect auditory-verbal working memory and sustained attention. Conclusion: tDCS to the left DLPFC improved visual-verbal working memory in ADHD patients, with important implications for potential ADHD treatments.

Unleashing the Potential of Unidirectional Mechanical Materials: Breakthroughs and Promising Applications

The emergence of mechanically one-way materials presents an exciting opportunity for materials science and engineering. These substances exhibit unique nonreciprocal mechanical responses, enabling them to selectively channel mechanical energy and facilitate directed sound propagation, controlled mass transport, and concentration of mechanical energy amidst random motion. This article explores the fundamentals of mechanically one-way materials, their potential applications across various industries, and the economic and environmental considerations related to their production and use.

从直接血管内取栓与标准静脉溶栓桥接血管内取栓治疗发病4.5 h内卒中的随机对照研究(DIRECT-SAFE)看桥接治疗的未来

桥接治疗是指在静脉溶栓基础上进行动脉血管内介入治疗。目前,已完成了6项随机对照研究及多项真实世界研究来对比直接血管内取栓与静脉溶栓桥接血管内取栓治疗急性卒中患者的疗效。该文对上述研究进行总结,并着重分析直接血管内取栓与标准静脉溶栓桥接血管内取栓治疗发病4.5 h内卒中的随机对照研究(DIRECT-SAFE)的结果来探讨桥接治疗的未来,以期为临床实践提供参考。

中国石油深层、超深层油气勘探进展与启示

近年来,中国石油天然气股份有限公司(以下简称中国石油)在陆上深层、超深层油气领域勘探持续获得突破,形成了一批规模储量区,展现出了巨大的油气勘探潜力。为了进一步明确未来中国石油深层、超深层油气勘探方向,在对中国石油近期油气勘探发展形势和新进展分析的基础上,将深层、超深层重点勘探突破进行了领域细分,并系统梳理了中国石油未来油气勘探重点区带并开展了排队优选研究,最后总结了各领域的勘探经验和启示。研究结果表明:①深层、超深层领域可细分为海相碳酸盐岩、碎屑岩及复杂岩性地层、前陆冲断带、深层页岩气4大领域;②向深层进军寻找突破是中国石油未来油气勘探的战略选择,也是未来中国石油油气勘探的重点,应分层次、突出重点部署,积极寻找规模新发现和大突破;③中国石油深层、超深层4大领域勘探程度低、剩余资源潜力大,根据目前勘探进展,初步梳理出40个未来油气勘探重点区带,其中石油地质资源量为39.4×10^(8)t,天然气地质资源量为39.6×10^(12)m^(3),油气勘探潜力巨大。结论认为,深层、超深层是规模油气发现的重大现实领域,保持战略定力、持续加大技术攻关和新领域的探索力度、不断创新理论认识、突破技术瓶颈是加快深层、超深层油气规模勘探开发的重要举措。

煤矿智能快速掘进关键技术研究现状及展望

针对煤矿巷道掘进智能化建设情况,探讨了现阶段分别以连采机、掘锚一体机、全断面掘进系统、掘锚机为核心的四大类智能快速掘进成套装备发展现状,分析了四大类智能快掘装备与地质条件适用性,提出了实现煤矿智能化掘进需要解决的关键技术的问题,探讨了以信息传输与智能分析技术、智能感知技术、精确定位导航技术,自主定型定向截割技术、掘进机远程自主截割控制技术以及多级多工序智能协同控制技术为基础的智能化掘进实现途径;基于复杂地质条件下煤矿巷道掘进亟待解决的关键问题,提出了以掘进作业功能需求、掘进工艺要求为依据的系统化分析、模块化设计、功能优化组合的设计方法;研究了以虚控实、虚实结合的多级数字孪生构架,基于掘进巷道设备、环境、地质构造多维信息再现实现掘进机远程控制;提出了单机智能化、系统协同化、井下智控与地面远程监控相协同的控制方法。开发了新型的无重复碾压柔性超前支护技术、截割部多级伸缩截割技术、智能锚固机组多钻机并行作业等技术,研制了具有掘、支、锚、运、探多工序并行作业的新型快速掘进作业联合机组,提出了掘进机器人、超前支护机器人、锚固机器人、辅助运输机器人组柔性并行作业技术;提出了基于数据驱动的多机多工序协同控制行为规划决策方法。提出构建完整的煤矿井下跨系统全时空信息数字感知体系,构建集井下现场生产状态、掘进巷道空间信息、掘进装备状态、风险信息等多参量、多尺度、全时空特性的数据感知智能化监控平台,实现虚拟系统与实际掘进系统实时通信,通过数据驱动规划分析实现智能化、少人化掘进。

火山灰质材料的火山灰活性检测方法综述

本文将火山灰质材料的火山灰活性检测方法分为直接法和间接法两大类。其中,直接法包括石灰吸收值法,火山灰反应程度评定法和酸、碱溶出度法;而间接法包括物理性能法,水化反应放热量法和物理、化学特征参数法。为正确指导火山灰活性检测方法的应用,本文详细介绍并比较了各检测方法的原理和特点。笔者认为,直接法可直接测定出火山灰质材料与Ca(OH)2反应的程度,但其操作和分析过程相对复杂;间接法可通过测定火山灰质材料对体系物化性能的影响或材料自身的物理、化学特征参数来评价其火山灰活性。本文从材料科学的角度厘清了各检测方法的适用对象,认为应根据不同的火山灰质材料的特性选择与其相适应的火山灰活性检测方法。

动态风向变化下风力机叶片和塔架应力及功率特性分析

风向变化显著影响风力机气动载荷分布,从而影响风力机稳定高效的运行,而气动载荷是风力机结构应力和功率变化主要影响因素之一。该文以S翼型三叶片水平轴风力机为研究对象,在旋转平台上进行风洞实验,对不同风向变化速度(0.5°、1°、1.5°、2°/s)下风力机叶片和塔架的应力以及风力机功率特性进行分析。结果表明:风向变化速度为0.5°/s时,在风向由0°变化到30°时,叶片弦向和展向应力值和风力机功率下降幅度最大;在风向由0°变化到20°时,叶片应力值和功率下降较为缓慢,风向变化结束后,风力机应力与功率会进一步减小;风向变化角度在0°~20°范围内,受叶片转速和气动载荷下降速度与风向变化耦合作用的影响,塔架应力值出现较大波动,并随风向变化速度的增加,波动出现的区间从15°~20°提前到0°~5°;风向变化结束后,叶片转速持续下降,造成塔架应力仍有不同程度的波动。结果可为考虑风向变化下运行的风力机结构设计提供一定理论依据。

柴达木盆地南八仙地区渐新世浅水三角洲物源及沉积演化

以古近系渐新统下干柴沟组上段(E23)为研究对象,在精细岩芯观察和钻(测)井资料综合分析的基础上,结合重矿物组合、ZTR指数、砂岩碎屑组分、粒度累积概率图和砂地比等参数综合分析结果,对柴达木盆地南八仙地区E23湖盆扩张期弱退积型浅水三角洲物源方向、砂体展布规律和沉积微相发育演化进行了深入研究。结果表明:①南八仙地区E23沉积时期物源主要来自南祁连山中酸性岩浆岩和中高级变质岩发育区,物源方向为近北东—南西向,稳定重矿物(磁铁矿、石榴子石、白钛矿和锆石)含量高(质量分数介于81.0%~99.9%)、不稳定重矿物(绿帘石和角闪石)含量低。②南八仙地区E23沉积时期为浅水三角洲—滨浅湖沉积环境,主要发育水下分流河道砂体,岩性主要为岩屑长石砂岩,其次为长石岩屑砂岩,砂体的成分成熟度一般中等—较差、分选磨圆度中等—较差,粒度概率图以反映河流作用的一跳跃一悬浮式为主;沉积构造类型多样,主要发育块状层理、正粒序层理、平行层理和槽状交错层理。③E23沉积时期,南八仙地区继承性发育3条北东—南西向呈条带状展布的砂体富集带(砂地比值介于35%~65%之间),早期到中期砂体发育程度增强,呈进积式;中期到晚期砂体发育程度有所减弱,呈弱退积式。④E23沉积时期,南八仙地区处于浅水三角洲前缘亚相沉积环境,持续发育3个呈北东—南西向展布的沉积朵叶体,主要发育水下分流河道微相,其次为水下分流间湾微相,早期到中期浅水三角洲前缘发育规模增大,中期到晚期发育规模减小。

深化研究人文经济学:方向抉择、当代使命与未来前景

理论创新无止境,深化研究谋新篇。一年来,在全国上下理解和把握习近平总书记关于“人文经济学”的新思想新观点新论断的丰富内涵和重大要求取得初步进展之后,深化研究需要做出新的方向抉择,凝练当代议程,肩负当代使命。一是要立足更高站位进一步深刻理解和把握人文经济学命题出场语境与重大意义;二是要深耕样本解读,从实际出发追寻人文经济学出场的历史逻辑,从习近平总书记多次赞赏的苏州、杭州等地区的历史基础和实践经验中科学提炼“人文密码”,精准理解“人文经济学”的真正内涵;三是要植根实践逻辑,精准把握人文经济学推动高质量发展的着力点和战略全局;四是要回溯人文经济学的理论魂脉,看人文经济学在解决西方经济学带来的一系列弊病的过程中,如何守正创新了马克思对资本拜物教所作的深刻的政治经济学批判的思想,同时重新系统梳理习近平总书记关于“人文经济学”系列重要论断的思想逻辑;五是要整体有机贯通、历史性梳理人文经济学的文化根脉,揭示和把握从传统到现代经济发展中一脉相承、成为灵魂的“文化基因”图谱;六是要以强大的文化自信和理论自信加快构建新时代中国特色人文经济学自主知识体系,开辟马克思主义中国化时代化新境界,谱写中国式现代化理论创造的新篇章。深化研究必将呈现方向和领域的分工甚至分化,需要加强协同创新机制建设。

中国水层CO_(2)地质封存技术攻关方向

在国家“碳达峰碳中和”战略目标下,为了延长化石能源行业的生命周期,亟需进行大规模碳减排的重大革命,其中CO_(2)地质封存(CCS)这一大规模碳减排的托底技术,已在全球达成共识。为此,系统梳理了全球CCS发展趋势,并针对中国CCS地质特点和工程技术现状,分析了中国发展水层CCS面临的挑战和难点,提出了中国水层CO_(2)地质封存技术的攻关方向。研究结果表明:①中国水层CCS起步早,当前正在开展世界级规模水层CCS先导试验,技术水平与国外并行,CCS有望成为中国未来大规模碳减排的主要手段;②鉴于中国水层多无法回避陆相沉积、断裂发育、非均质性强等先天条件,中国未来建设大规模水层CCS将面临封存规模大、封存成本高和长期封存安全性等3个方面关键技术的挑战;③从推动和形成CCS负碳新产业角度,中国未来水层CCS碳埋存需要攻克CCS地质体评估、CO_(2)高速注入、低浓度CO_(2)封存、降低成本和地质监测等5个关键技术。结论认为,该研究认识进一步坚定了中国发展水层CCS技术的信心,提出的5个方面关键技术为快速形成负碳领域的国家战略科技力量明确了攻关方向,同时为后续推动大规模地下储氢、储氦、压缩空气储能等战略性新兴行业的发展提供了前瞻性技术支撑。

终身学习数字化转型的哲学观与创新方向

教育数字化转型是教育领域的一场系统性、根本性变革,这是教育适应数字时代发展的必然要求,也是建设服务全面终身学习教育体系的重要途径。教育数字化转型涉及教育全要素、全流程、全领域的创新与变革过程。在新的发展阶段,面向学习型社会建设,终身学习领域要深刻理解教育数字化转型阶段终身学习信息化的方向,关注教育哲学思想的发展,持续推进体制机制改革;树立全新的教育哲学观,即联通主义学习观、回归论知识观和教育的复杂系统观。在新哲学观指导下,通过互联网、人工智能技术等新兴技术的加持,可以从四个方向创新推进终身学习数字化转型:建设互联互通的网络学习空间,整合全社会资源满足多样化学习需要,探索新型教育服务供给模式,建立健全终身学习立交桥制度。

基于四行精密播种的玉米直播机设计与试验

为了解决播种玉米种子精度低的问题,设计了一款基于四行精密播种的玉米直播机,可实现玉米种子快速、精准播种。试验表明:该玉米直播机移动性能好、播种速度快、种植深度和每穴种子数量更加准确,封土情况也大幅改善,符合设计需求,具有较高的可靠性和可行性。

基于新能源-负荷相似性的源荷储协调调峰优化调度

合理利用可调节负荷的响应特性来实现源荷储的协调调度,可有效缓解新能源、负荷的不确定性所带来的调峰压力。基于新能源-负荷(NER-L)相似性,建立可调节负荷响应目标。基于相关系数,建立能准确刻画负荷对新能源出力跟踪匹配程度的NER-L相似性指标,并将指标引入所建源荷储协调调峰的双阶段优化调度模型。第一阶段模型以NER-L相关系数最大为目标,确定可调节负荷在各时段的响应功率并获得最优电网负荷;第二阶段模型以弃风弃光量最小、调峰运行成本最低为目标,优化火电机组及储能出力。以IEEE 30节点系统为例,对NER-L相似性、净负荷峰谷差、系统调峰运行经济性及新能源弃电功率进行计算分析,结果验证了所提模型的有效性。

移动机器人视觉里程计技术研究综述

随着移动机器人技术不断发展,里程计技术已经成为移动机器人实现环境感知的关键技术,其发展水平对提高机器人的自主化和智能化具有重要意义。首先,系统阐述了同步定位与地图构建(Simultaneous localization and mapping,SLAM)中激光SLAM和视觉SLAM的发展近况,阐述了经典SLAM框架及其数学描述,简要介绍了3类常见相机的相机模型及其视觉里程计的数学描述。其次,分别对传统视觉里程计和深度学习里程计的研究进展进行系统阐述。对比分析了近10年来各类里程计算法的优势与不足。另外,对比分析了7种常用数据集的性能。最后,从精度、鲁棒性、数据集、多模态等方面总结了里程计技术面临的问题,从提高算法实时性、鲁棒性等方面展望了视觉里程计的发展趋势为:更加智能化、小型化新型传感器的发展;与无监督学习融合;语义表达技术的提高;集群机器人协同技术的发展。

结合主动光源和改进YOLOv5s模型的夜间柑橘检测方法

【目的】解决夜间环境下遮挡和较小柑橘难以准确识别的问题,实现采摘机器人全天候智能化作业。【方法】提出一种结合主动光源的夜间柑橘识别方法。首先,通过分析主动光源下颜色特征不同的夜间柑橘图像,选择最佳的光源色并进行图像采集。然后,提出一种夜间柑橘检测模型BI-YOLOv5s,该模型采用双向特征金字塔网络(Bi-FPN)进行多尺度交叉连接和加权特征融合,提高对遮挡和较小果实的识别能力;引入Coordinate attention(CA)注意力机制模块,进一步加强对目标位置信息的提取;采用融入Transformer结构的C3TR模块,在减少计算量的同时更好地提取全局信息。【结果】本文提出的BI-YOLOv5s模型在测试集上的精准率、召回率、平均准确率分别为93.4%、92.2%和97.1%,相比YOLOv5s模型分别提升了3.2、1.5和2.3个百分点。在所采用的光源色环境下,模型对夜间柑橘识别的正确率为95.3%,相比白光环境下提高了10.4个百分点。【结论】本文提出的方法对夜间环境下遮挡和小目标柑橘的识别具有较高的准确性,可为夜间果蔬智能化采摘的视觉精准识别提供技术支持。