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Research on Partial Coefficients for Design of Quarter-circular Caisson Breakwater 被引量:4
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作者 Luwen Qie Xiang Zhang +1 位作者 Xuelian Jiang Yinan Qin 《Journal of Marine Science and Application》 2013年第1期65-71,共7页
The quarter-circular caisson breakwater (QCB) is a new type of breakwater, and it can be applied in deepwater. The stability of QCB under wave force action can be enhanced, and the rubble mound engineering can be le... The quarter-circular caisson breakwater (QCB) is a new type of breakwater, and it can be applied in deepwater. The stability of QCB under wave force action can be enhanced, and the rubble mound engineering can be less than that of semi-circular breakwaters in deepwater. In order to study the wave force distribution acting on the QCB, to find wave force formula for this type of breakwater, firstly in this paper, the distribution characteristics of the horizontal force, the downward vertical force and the uplift force on the breakwater were gotten based on physical model wave flume experiments and on the analysis of the wave pressure experimental data. Based on a series of physical model tests acted by irregular waves, a kind of calculation method, which was modified by Goda formula, was proposed to carry out the wave force on the QCB. Secondly, the reliability method with correlated variables was adopted to analyze the QCB, considering the high correlation between wave forces or moments. Utilizing the observed wave data in engineering field, the reliability index and failure probability of QCB were obtained. Finally, a factor Q=0.9 is given to modify the zero pressure height above SWL of QCB, and wave force partial coefficient 1.34 to the design expressions of QCB for anti-sliding, as well as 1.67 for anti-overturning, were presented. 展开更多
关键词 quarter-circular caisson breakwater (qcb) wave force modified Goda formula reliability index partial coefficient
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清肠宝对溃疡性结肠炎小鼠模型IL-4和IFN-y水平的影响
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作者 荣新奇 戴紫登 赵亮 《中国肛肠病杂志》 2006年第7期9-11,共3页
通过溃疡性结肠炎(UC)葡聚糖硫酸钠(DSS)动物模型,研究清肠宝调控UC的效果及对IL-4和IFN-γ水平的影响,探讨清肠宝调控UC的机制。将40只昆明小鼠随机分成标准模型组、正常组、清肠宝组和柳氮磺吡啶(SASP)组,在造模同时分别灌... 通过溃疡性结肠炎(UC)葡聚糖硫酸钠(DSS)动物模型,研究清肠宝调控UC的效果及对IL-4和IFN-γ水平的影响,探讨清肠宝调控UC的机制。将40只昆明小鼠随机分成标准模型组、正常组、清肠宝组和柳氮磺吡啶(SASP)组,在造模同时分别灌胃。各组于7d后,用酶联免疫吸附法(ELISA)检测血清中IL-4和IFN-γ含量;观察各组小鼠的体重变化、结肠重量和溃疡点数;用光学显微镜观察各组结肠组织的病理变化。结果表明,清肠宝具有调控DSS诱导的小鼠溃疡性结肠炎模型及其Th1和Th2 细胞亚群细胞因子IL-4和IFN-γ的作用。清肠宝具有防止DSS模型结肠重量减轻和减少溃疡形成的作用。 展开更多
关键词 清肠宝 结肠炎 溃疡性 IL-4 IFN-γ
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