针对脉冲位置相位翻转键控(Pulse Position Phase Reversal Keying,3PRK)调制的解调问题,基于时频分析方法,对3PRK信号的伪魏格纳-威利(PWVD)分布特性进行了详细分析,建立了3PRK调制信号相位突变与PWVD分布幅度的关系模型,利用该模型提...针对脉冲位置相位翻转键控(Pulse Position Phase Reversal Keying,3PRK)调制的解调问题,基于时频分析方法,对3PRK信号的伪魏格纳-威利(PWVD)分布特性进行了详细分析,建立了3PRK调制信号相位突变与PWVD分布幅度的关系模型,利用该模型提出了一种新的基于PWVD分布的3PRK调制解调算法,并对该解调算法性能进行了仿真分析。仿真结果验证了该算法的有效性。展开更多
This paper introduces throughput-efficient wireless system based on an extension to binary phasemodulations,named extended binary phase shift keying(EBPSK),and the corresponding analysis ofpower spectra,especially the...This paper introduces throughput-efficient wireless system based on an extension to binary phasemodulations,named extended binary phase shift keying(EBPSK),and the corresponding analysis ofpower spectra,especially the extension to channel capacity are given.Importantly,a novel sequential es-timation and detection approach for this EBPSK system is proposed.The basic idea is to design a proba-bilistic approximation method for the computation of the maximum a posterior distribution via particle fil-tering method(PF).Subsequently,a new important function in PF is presented,so that the performanceof the detector has a great improvement.Finally,computer simulation illustrates that EBPSK system hasvery high transmission rate,and also the good performance of the proposed PF detector is demonstrated.展开更多
Preoperative staging of the axilla in women with invasive breast cancer using ultrasound-guided needle biopsy(UNB) identifies approximately 50% of patients with axillary nodal metastases prior to surgical intervention...Preoperative staging of the axilla in women with invasive breast cancer using ultrasound-guided needle biopsy(UNB) identifies approximately 50% of patients with axillary nodal metastases prior to surgical intervention. Although moderately sensitive, it is a highly specific staging strategy that is rarely falsely-positive, hence a positive UNB allows patients to be triaged to axillary lymph-node dissection(ALND) avoiding potentially unnecessary sentinel node biopsy(SNB). In this review, we extend our previous work through an updated literature search, focusing on studies that report data on UNB utility. Based on data for 10,934 breast cancer patients, sourced from 35 studies, a positive UNB allowed triage of 1,745 cases(simple proportion 16%) to axillary surgical treatment: the utility of UNB was a median 19.8% [interquartile range(IQR) 11.6%-26.7%] across these studies. We also modelled data from a subgroup of studies, and estimated that amongst patients with metastases to axillary nodes, the odds ratio(OR) for high nodal disease burden for a positive UNB versus a negative UNB was 4.38 [95% confidence interval(95% CI): 3.13, 6.13], P<0.001. From this model, the estimated proportion with high nodal disease burden was 58.9%(95% CI: 50.2%, 67.0%) for a positive UNB, whereas the estimated proportion with high nodal disease burden was 24.6%(95% CI: 17.7%, 33.2%) if UNB was negative. Overall, axillary UNB has good clinical utility and a positive UNB can effectively triage to ALND. However, the evolving landscape of axillary surgical treatment means that UNB will have relatively less utility where surgeons have modified their practice to omission of ALND for minimal nodal metastatic disease.展开更多
文摘针对脉冲位置相位翻转键控(Pulse Position Phase Reversal Keying,3PRK)调制的解调问题,基于时频分析方法,对3PRK信号的伪魏格纳-威利(PWVD)分布特性进行了详细分析,建立了3PRK调制信号相位突变与PWVD分布幅度的关系模型,利用该模型提出了一种新的基于PWVD分布的3PRK调制解调算法,并对该解调算法性能进行了仿真分析。仿真结果验证了该算法的有效性。
基金Supported by the National Natural Science Foundation of China (No. 60872075)China Postdoctoral Science Foundation (No. 20080441015)
文摘This paper introduces throughput-efficient wireless system based on an extension to binary phasemodulations,named extended binary phase shift keying(EBPSK),and the corresponding analysis ofpower spectra,especially the extension to channel capacity are given.Importantly,a novel sequential es-timation and detection approach for this EBPSK system is proposed.The basic idea is to design a proba-bilistic approximation method for the computation of the maximum a posterior distribution via particle fil-tering method(PF).Subsequently,a new important function in PF is presented,so that the performanceof the detector has a great improvement.Finally,computer simulation illustrates that EBPSK system hasvery high transmission rate,and also the good performance of the proposed PF detector is demonstrated.
基金partly funded by National Health and Medical Research Council (NHMRC) program (Grant No. 633003) to the Screening & Test Evaluation Program, Australia
文摘Preoperative staging of the axilla in women with invasive breast cancer using ultrasound-guided needle biopsy(UNB) identifies approximately 50% of patients with axillary nodal metastases prior to surgical intervention. Although moderately sensitive, it is a highly specific staging strategy that is rarely falsely-positive, hence a positive UNB allows patients to be triaged to axillary lymph-node dissection(ALND) avoiding potentially unnecessary sentinel node biopsy(SNB). In this review, we extend our previous work through an updated literature search, focusing on studies that report data on UNB utility. Based on data for 10,934 breast cancer patients, sourced from 35 studies, a positive UNB allowed triage of 1,745 cases(simple proportion 16%) to axillary surgical treatment: the utility of UNB was a median 19.8% [interquartile range(IQR) 11.6%-26.7%] across these studies. We also modelled data from a subgroup of studies, and estimated that amongst patients with metastases to axillary nodes, the odds ratio(OR) for high nodal disease burden for a positive UNB versus a negative UNB was 4.38 [95% confidence interval(95% CI): 3.13, 6.13], P<0.001. From this model, the estimated proportion with high nodal disease burden was 58.9%(95% CI: 50.2%, 67.0%) for a positive UNB, whereas the estimated proportion with high nodal disease burden was 24.6%(95% CI: 17.7%, 33.2%) if UNB was negative. Overall, axillary UNB has good clinical utility and a positive UNB can effectively triage to ALND. However, the evolving landscape of axillary surgical treatment means that UNB will have relatively less utility where surgeons have modified their practice to omission of ALND for minimal nodal metastatic disease.
