Ostrowski’s Type Inequalities for Generalized(h,m)−Preinvex Functions with Its Applications

A new concept generalized(h,m)−preinvex function on Yang’s fractal sets is proposed.Some Ostrowski’s type inequalities with two parameters for generalized(h,m)−preinvex function are established,where three local fractional inequalities involving generalized midpoint type,trapezoid type and Simpson type are derived as consequences.Furthermore,as some applications,special means inequalities and numerical quadratures for local fractional integrals are discussed.

(h,)-Lipschitz函数及其广义方向导数和广义梯度

借助于Ben—Tal广义代数运算引进了一种新的函数-(h,)-Lipschitz函数．讨论了它与Lipschitz函数之间的关系,给出了它的广义方向导数和广义梯度,得到了它们的若干性质．作为应用,给出了广义方向导数与切锥之间的关系。

Insights into SO_2 and H_2O co-adsorption on Cu(100) surface with calculations of density functional theory

The co-adsorption behaviors of SO2 and H2 O on face-centered cubic Cu（100） ideal surface were studied using the GGA-r PBE method of density functional theory（DFT） with slab models. The optimized structures of single H2 O and SO2 on Cu（100） surface were calculated at the coverage of 0.25 ML（molecular layer） and 0.5 ML. The results show that there was no obvious chemical adsorption of them on Cu（100） surface. The adsorbed structures, adsorption energy and electronic properties including difference charge density, valence charge density, Bader charge analysis and partial density of states（PDOS） of co-adsorbed structures of H2 O and SO2 were investigated to illustrate the interaction between adsorbates and surface. H2 O and SO2 can adsorb on surface of Cu atoms chemically via molecule form at the coverage of 0.25 ML, while H2 O dissociated into OH adsorbed on surface and H bonded with SO2 which keeps away from surface at the coverage of 0.5 ML.

叶酸联合依那普利治疗老年H型高血压的效果及对血管内皮功能和Hcy水平的影响

目的 观察叶酸联合依那普利治疗老年H型高血压的效果及对血管内皮功能和同型半胱氨酸(Hcy)水平的影响。方法 选取2019年10月—2020年10月昆明医科大学第一附属医院收治的老年H型高血压患者82例,根据随机数字表法分为观察组和对照组,每组41例。对照组予马来酸依那普利片治疗,观察组在对照组基础上加用叶酸片治疗,2组均治疗3个月。比较2组临床疗效,治疗前后血压情况、血管内皮损伤指标[一氧化氮(NO)、血管内皮素(ET-1)]、颈动脉内—中膜厚度(IMT)、血清Hcy、血浆可溶性细胞间黏附分子-1(sICAM-1)水平及不良反应。结果 观察组治疗总有效率为95.12%,高于对照组的78.05%(χ^(2)=5.145,P=0.023)。治疗3个月后,2组收缩压、舒张压低于治疗前,且观察组低于对照组(P<0.01);2组NO水平较治疗前升高,ET-1水平较治疗前降低,且观察组升高/降低幅度大于对照组(P<0.01);2组IMT较治疗前减小,血清Hcy、血浆sICAM-1水平较治疗前降低,且观察组低于对照组(P<0.01)。观察组与对照组不良反应总发生率均为4.88%,差异无统计学意义(P>0.05)。结论 叶酸联合依那普利治疗老年H型高血压疗效显著,控制血压效果更佳,并能改善血管内皮损伤,降低Hcy水平及心脑血管疾病的发病风险,且不良反应发生率低。

肺源性心脏病患者24h动态心电图参数与肺功能的相关性及对不良事件的预测价值

目的探究肺源性心脏病(PHD)患者动态心电图参数与肺功能的相关性及对不良事件的预测价值。方法选取PHD患者73例为观察组,并纳入同期健康志愿者42例为对照组,两组均接受24 h动态心电图和肺功能检测;比较入组时两组被检者及观察组患者治疗前、治疗后第7天时24 h动态心电图参数[24 h RR间期标准差(SDNN)、每5 min时段正常RR间期标准差(SDANN)]和肺功能指标[1秒用力呼气容积(FEV1)/用力肺活量(FVC)、FEV1预计百分比(FEVl%)];随访6个月,根据不良事件发生情况将观察组分为预后良好组和预后不良组,比较两组患者临床特征,分析24 h动态心电图参数与肺功能的相关性及其对PHD不良事件的预测价值。结果观察组入院后SDNN、SDANN、FEV1/FVC、FEVl%低于对照组(P<0.05),73例PHD患者在治疗后第7天时的SDNN、SDANN、FEV1/FVC、FEVl%较治疗前升高(P<0.05);随访6个月,73例PHD患者中有32例出现不良事件,预后不良组急性加重期占比、平均病程均高于预后良好组(P<0.05),预后不良组治疗前、治疗后第7天时SDNN、SDANN、FEV1/FVC、FEVl%均低于预后良好组(P<0.05);Pearson相关分析结果显示,治疗前及治疗后第7天时SDNN、SDANN均与治疗前及治疗后第7天时FEV1/FVC、FEVl%呈正相关(P<0.05);ROC分析结果显示,PHD患者发生不良事件的治疗前、治疗后第7天时SDNN、SDANN的cut-off值分别为72 ms、55 ms、92 ms、91ms,AUC范围在0.702~0.813(P<0.05)。结论PHD患者治疗前及治疗后7 d的SDNN、SDANN与肺功能呈正相关,24 h动态心电图参数对PHD不良事件的具有一定的预测价值。

带扰动补偿的永磁同步电机鲁棒H∞控制

为了提高永磁同步电机调速系统的抗干扰能力,提出了一种鲁棒H∞控制方法。首先,根据鲁棒H∞控制原理,提出了永磁同步电机H∞速度控制设计方法,并介绍了求解方法。设计加权函数时考虑了跟踪性能、干扰抑制、输出限制和模型不确定性。通过伯德图详细说明了性能加权函数对动态性能的影响,并给出了加权函数的设计方法。然后,在考虑参数不确定性和未建模动态的情况下,为进一步提高系统的抗干扰能力,通过Luenberger扰动观测器将扰动作为前馈补偿观测,并将其反馈到速度控制器中,以加速动态响应,增强对扰动的抑制能力。最后,通过试验对比了传统比例积分控制器、H∞速度控制器和所提的复合速度控制器,试验结果验证了所提复合速度控制器的有效性。

On the Fekete-Szeg5 Problem for a Class of Analytic Functions

The Fekete-Szego inequality for a subclass H(α,λ,A,B) of the class H of normalized analytic functions is studied.For each f(z)=z+~∞∑_(n=2)αnz^n ∈ H(α,λ,A,B),the sharp upper bounds of |α_3-α_2~2|for any complex parameter u are obtained by using the fundamental inequalities of analytic functions and analytical techniques and the applications of the inequality of functions defined with Hadaniard product are proved.

Effect of Haimiding on the functioning of red cell membrane of FC and H_(22) tumor-bearing mice

AIM: To study the effect of Haimiding on the functioning of red cell membrane of FC and H22 tumor-bearing mice. METHODS: The membrane fluidity of red cells is measured with DPH fluorescence probe as a marker; the amount of red cell membrane proteins is measured using polyacrylamide gel electrophoresis; the amount of sialic acid (SA) on the surface of red cell membrane and the scalability of these cells are measured using colorimetric analysis. RESULTS: Haimiding can lower the membrane fluidity of red cells in tumor-bearing mice and the amount of their membrane proteins, while increasing the amount of sialic acid in the membrane of red cells in these mice and enhancing the ability of the membrane of their red cells to reseal. CONCLUSION: The anti-tumor effect of Haimiding on tumor-bearing mice is due to its ability to improve and restore the functions of the membrane of their red cell and to enhance the immune effect of the organisms.

Sufficient Optimality Conditions for Multiobjective Programming Involving (V, ρ)h,ψ-type Ⅰ Functions

New classes of functions namely (V, ρ)_(h,φ)-type I, quasi (V, ρ)_(h,φ)-type I and pseudo (V, ρ)_(h,φ)-type I functions are defined for multiobjective programming problem by using BenTal's generalized algebraic operation. The examples of (V, ρ)_(h,φ)-type I functions are given. The sufficient optimality conditions are obtained for multi-objective programming problem involving above new generalized convexity.

Delay-dependent Non-fragile H_∞ Filtering for Uncertain Fuzzy Systems Based on Switching Fuzzy Model and Piecewise Lyapunov Function

This paper is concerned with the non-fragile H∞ filter design problem for uncertain discrete-time Takagi-Sugeno （T-S） fuzzy systems with time delay. To begin with, the T-S fuzzy system is transformed to an equivalent switching fuzzy system. Then, based on the piecewise Lyapunov function and matrix decoupling technique, a new delay-dependent non-fragile H∞ filtering method is proposed for the switching fuzzy system. The proposed condition is less conservative than the previous results. Since only a set of LMIs is involved, the filter parameters can be solved directly. Finally, a design example is provided to illustrate the validity of the proposed method.

Photo-/electrocatalytic functionalization of quinoxalin-2(1H)-ones

The photo-/electrocatalytic functionalization of quinoxalin-2(1H)-ones has emerged as a promising and powerful approach for post-synthetic modification of quinoxalin-2(1H)-ones.This review provides an overview of recent developments in photo-/electrocatalytic functionalization of quinoxalin-2(1H)-ones including arylation,alkylation,fluoroalkylation,amination,phosphorylation,acylation,alkoxylation,thiolation,silylation,and annulation.The reaction scope and the related mechanism are also well discussed.

Effects of hydroxyl group on H_2 dissociation on graphene:A density functional theory study

Graphene-based materials are promising for hydrogen production and storage. In this work, using density functional theory calculations, we explored how a hydroxyl group influences H2 dissociation on graphene. Presence of the hydroxyl group makes the binding of H atom with graphene stronger, as the binding energy of H atom with the hydroxyl-modified graphene is higher than that with the pristine graphene. The para-site is the most favorable site for H2 dissociation on both the pristine and hydroxyl-modified graphene. The energy barrier of H2 dissociation at para-site on the pristine graphene is 3.10 eV whereas that on the hydroxyl-modified graphene is 2.46 eV, indicating a more facile H2 dissociation on the hydroxyl-modified graphene.

Precisely decorating CdS on Zr-MOFs through pore functionalization strategy: A highly efficient photocatalyst for H2 production

Different materials,such as metal sulphides,are often combined with metal‐organic frameworks(MOFs)to develop multi‐functional composites and improve their photocatalytic properties.However,the high interfacial energy barrier limits the formation and nano‐assembly of the heterogeneous junctions between MOFs and metal sulphides.Herein,the heterostructured Zr‐MOF‐S@CdS are successfully constructed through a sequential synthesis method,in which the mesoporous Zr‐MOF are firstly decorated with thioglycolic acid through pore functionalization,and followed by the S^(2-)anion exchange process resulting in the surface close attached growth of CdS onto Zr‐MOF‐S materials.Due to the presence of molecules linkers,the CdS can be precisely decorated onto Zr‐MOF‐S without aggregation,which can provide more active sites.Moreover,the intimate connections and the suitable band structures between two materials can also facilitate the photogenerated electron‐hole pairs separation.Therefore,the resulting Zr‐MOF‐S@CdS with appropriate ratio exhibits high photocatalytic activity for water reduction,in which the H_(2) evolution rate can reach up to 1861.7μmol·g^(‒1)·h^(‒1),4.5 times higher than pure CdS and 2.3 times higher than of Zr‐MOF/CdS,respectively.Considering the promising future of MOF‐based photocatalysts,this work may provide an avenue for the further design and synthesis MOF‐based composite photocatalysts for efficient H_(2) evolution.

Density Functional Theory Study for Adsorption of Oxygen and Water Molecules on 6H-SiC(0001) Surface

6H-SiC is an important semiconductor material. The 6H-SiC wafer is always exposed to a high-humidity environment and the effect from the absorbed water molecule and some relative adsorbates is not negligible. Here, the oxygen and water molecules absorbed on the 6H-SiC(0001) surface and the dissociation process were studied with density functional theory. On the 6H-SiC(0001) surface, absorbed O2 is spontaneously dissociated into O*, which is absorbed on a hollow site, and further transforms the 6H-SiC(0001) surface into SiO2. The absorbed H2O is spontaneously broken into OH*and H*, which are both absorbed on the top of the Si atom, and OH* is further reversibly transformed into O* and H*. The H* could saturate the dangling Si bond and change the absorption type of O*, which could stabilize the 6H-SiC(0001) surface and prevent it from transforming into SiO2.

老年人群24h动态血压监测中清晨高血压与脑血管储备功能相关性

目的研究老年人群24 h动态血压监测中清晨高血压与脑血管储备功能(CVR)的相关性。方法回顾性选取2021年1月至12月到济南市妇幼保健院行24 h动态血压监测的300例老年受试者,依据监测结果分为A组、B组和C组。A组158例为清晨血压升高的高血压患者,男88例,女70例,年龄(66.02±4.35)岁;B组74例为清晨血压正常的高血压患者,男41例,女33例,年龄(65.42±4.42)岁;C组68例为血压正常者,男37例,女31例,年龄(65.77±4.38)岁。以两侧大脑中动脉屏气指数均值<0.69%为CVR减低,屏气指数均值≥0.69%为CVR正常,将300例受试者分为CVR降低组(52例)和CVR正常组(248例)。比较A、B、C 3组患者的临床资料,CVR指标;比较CVR降低组、CVR正常组一般资料,行单因素分析、多因素分析和相关性分析。采用F检验、独立样本t检验、χ^(2)检验、logistic回归分析和Pearson相关性分析。结果300例24 h动态血压监测的老年受试者,清晨血压升高的高血压患者158例,占52.67%;清晨血压正常的高血压患者74例,占24.67%;血压正常者68例,占22.67%。3组收缩压(24 h均值、日间均值、夜间均值)、晨峰指数:A组>B组>C组(均P<0.05);舒张压(24 h均值、日间均值、夜间均值):A组>B组、C组(均P<0.05),B组、C组舒张压比较,差异均无统计学意义(均P>0.05)。CVR:A组[(21.37±7.89)%]<B组[(25.58±8.14)%]<C组[(28.56±8.10)%](均P<0.05);屏气指数:A组[(0.89±0.23)%]<B组[(1.13±0.21)%]、C组[(1.20±0.24)%](均P<0.05),B组、C组屏气指数比较,差异无统计学意义(P>0.05);脉动指数:A组[(1.49±0.36)]>B组[(1.15±0.31)]、C组[(1.06±0.29)](均P<0.05),B组、C组脉动指数比较,差异无统计学意义(P>0.05)。CVR降低组年龄[(73.14±3.21)岁]、清晨收缩压[(132.42±9.64)mmHg](1 mmHg=0.133 kPa)、清晨舒张压[(68.85±6.59)mmHg]均高于CVR正常组[(64.28±4.36)岁、(121.58±7.26)mmHg、(65.36±7.23)mmHg](均P<0.05)。logistic回归分析结果显示:年龄、清晨收缩压、清晨舒张压均为CVR降低的影响因素(均P<0.05)。清晨收缩压与屏气指数呈负相关(P<0.05),与脉动指数呈正相关(P<0.05);清晨舒张压与屏气指数呈负相关(P<0.05),与脉动指数呈正相关(P<0.05)。结论老年人群24 h动态血压监测中清晨高血压患者占比较大,清晨高血压患者CVR、屏气指数较低,脉动指数较高,清晨收缩压、清晨舒张压均与屏气指数呈负相关,与脉动指数呈正相关。

Novel multi–SO_(3)H functionalized ionic liquids as highly efficient catalyst for synthesis of biodiesel

Biodiesel is an attractive alternative to fossil fuels due to the energy and environmental concerns. In this paper, seven different multi –SO_(3)H functionalized ILs based on the low-cost less-substituted amines, which contained massive sites for functionalization of sulfonic acid groups and further treatment of sulfonate-based anions, were prepared as catalysts with high acidity and desirable catalytic activity for the synthesis of biodiesel from the esterification of oleic acid with methanol. The physicochemical properties of these acidic ILs were characterized by a variety of analytical techniques such as FT-IR, EA, TGA, and the Br?nsted acidity was well determined by UV–vis. Among the ILs prepared, [EDA-PS][P-TSA] showed the highest catalytic activity for esterification due to its high acidity and appropriate miscibility with reactants, with an ultrahigh97.58% conversion of oleic acid under the optimum conditions(i.e. reaction time, 1.8 h;catalyst amount, 3 wt%;alcohol/acid molar ratio, 13:1,temperature 70℃) acquired from the Box–Behnken response surface methodology. With the novel strategy of multi –SO_(3) H modification on ILs,our catalyst had an approaching or even superior oleic acid conversion rate compared to other reported catalysts with considerably lower catalyst dosage and shorter reaction time. More importantly, it also exhibited high generality for converting various FFA feedstocks into biodiesel with considerable conversion within 93.59–94.33% under a rather lower catalyst dosage, which showed the valuable potential for converting low-cost oils into biodiesel from an economic and environmental perspective.

Pathophysiology of functional heartburn based on Rome Ⅲ criteria in Japanese patients

AIM:To investigate the pathophysiology of functional heartburn(FH) in Japanese patients.METHODS:A total of 111 patients with proton pump inhibitor(PPI)-refractory non-erosive gastroesophageal reflux disease underwent intraesophageal pressure testing and 24-h multichannel intraluminal impedancep H(24MII-p H) testing.The patients also completed several questionnaires while they were receiving the PPI treatment, including the questionnaire for the diagnosis of reflux disease(QUEST), the frequency scale for the symptoms of gastroesophageal reflux disease(FSSG), the gastrointestinal symptoms rating scale(GSRS), SF-36, and the Cornell Medical Index(CMI).The subjects were classified into FH and endoscopy-negative reflux disease(ENRD) groups based on the Rome Ⅲ criteria.RESULTS:Thirty-three patients with esophageal motility disorder were excluded from this study, while 22 patients with abnormal esophageal acid exposure time(p H-POS) and 34 with hypersensitive esophagus(HE) were included in the ENRD group.The FH group included 22 patients with no reflux involvement.Sex, age, and body mass index did not differ significantly between the groups.The mean SF-36 values were < 50(normal) for all scales in these groups, with no significant differences.The GSRS scores in these groups were not different and showed overlap with other gastrointestinal symptoms.The QUEST and the FSSG scores did not differ significantly between the groups.Neuroticism was diagnosed using the CMI questionnaire in 17 of the 78 included subjects within the p H-POS(n=4),HE(n=8),and FH(n=5)groups,with no significant differences.CONCLUSION:Clinical characteristics of the FH and PPI-refractory ENRD groups were similar.Therefore,esophageal function should be examined via manometry and 24MII-p H testing to differentiate between them.

THE HILBERT BOUNDARY VALUE PROBLEM FOR GENERALIZED ANALYTIC FUNCTIONS IN CLIFFORD ANALYSIS

Let R0,n be the real Clifford algebra generated by e1, e2,... , en satisfying eiej＋ejei=-2δij,i,j=1,2…,ne0 is the unit element.Let Ω be an open set. A function f is called left generalized analytic in ft if f satisfies the equation Lf=0,where ……qi 〉0, i =-, 1, - ……, n. In this article, we first give the kernel function for the generalized analytic function. Further, the Hilbert boundary value problem for generalized analytic functions in Rn＋1 will be investigated.

Up-regulation of tight junction-related proteins and increase of human epidermal keratinocytes barrier function by Saccharomycosis ferment filtrate

Saccharomycopsis ferment filtrate (SFF), mainly used in skin care products, has been reported to inhibit inflammatory nitric oxide production and prevent epidermal damage. However, the effects of SFF on epidermal keratinocytes have not yet been explored. We investigated the effects of SFF on skin barrier function using human primary epidermal keratinocytes. Cell viability was determined by MTT assay. The mRNA and protein expression levels of tight junction proteins (claudin-1, -3, -4, occludin, ZO-1) were analyzed by RT-PCR and Western blotting, respectively. The effect of SFF on the barrier formation of epidermal keratinocytes was measured by transepithelial electrical resistance (TER). Rescue of cell death from H2O2 treatment was evaluated by annexin V staining. SFF, at concentrations that did not cause significant change of cell viability, induced dose-dependent cell-cell adhesion and formation of an organized monolayer structure. Pretreatment of keratinocytes with EGTA, a Ca2+ chelator, did not inhibit the cell-cell adhesion of keratinocytes by SFF, indicating a Ca2+-independent mechanism. The mRNA and protein levels of claudin-1 in keratinocytes were up-regulated by SFF treatment in a dose-dependent manner. The expressions of other tight junctions (TJs) including claudin-3 & 4, occludin and ZO-1 were also similarly increased in SFF-treated epidermal keratinocytes. The promoting effect of SFF on the barrier function of epidermal keratinocytes was further confirmed by the increased TER value in SFF-treated epidermal keratinocytes. Annexin V staining confirmed that SFF markedly decreased the number of dead cells resulted from H2O2 injury. Taken together, our results provided the first evidence that SFF enhanced keratinocytes barrier function by increasing the expression of TJs and TER.

AREA INTEGRAL FUNCTIONS AND H∞ FUNCTIONAL CALCULUS FOR SECTORIAL OPERATORS ON HILBERT SPACES

Area integral functions are introduced for sectorial operators on Hilbert spaces. We establish the equivalence relationship between the square and area integral functions. This immediately extends McIntosh/Yagi＇s results on H∞ functional calculus of sectorial operators on Hilbert spaces to the case when the square functions are replaced by the area integral functions.