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Contract Mechanism of Water Environment Regulation for Small and Medium Sized Enterprises Based on Optimal Control Theory
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作者 Shuang Zhao Hongbin Gu +2 位作者 Lianfang Xue Dongsheng Wang Bin Huang 《Journal of Water Resource and Protection》 CAS 2024年第7期538-556,共20页
The small and scattered enterprise pattern in the county economy has formed numerous sporadic pollution sources, hindering the centralized treatment of the water environment, increasing the cost and difficulty of trea... The small and scattered enterprise pattern in the county economy has formed numerous sporadic pollution sources, hindering the centralized treatment of the water environment, increasing the cost and difficulty of treatment. How enterprises can make reasonable decisions on their water environment behavior based on the external environment and their own factors is of great significance for scientifically and effectively designing water environment regulation mechanisms. Based on optimal control theory, this study investigates the design of contractual mechanisms for water environmental regulation for small and medium-sized enterprises. The enterprise is regarded as an independent economic entity that can adopt optimal control strategies to maximize its own interests. Based on the participation of multiple subjects including the government, enterprises, and the public, an optimal control strategy model for enterprises under contractual water environmental regulation is constructed using optimal control theory, and a method for calculating the amount of unit pollutant penalties is derived. The water pollutant treatment cost data of a paper company is selected to conduct empirical numerical analysis on the model. The results show that the increase in the probability of government regulation and public participation, as well as the decrease in local government protection for enterprises, can achieve the same regulatory effect while reducing the number of administrative penalties per unit. Finally, the implementation process of contractual water environmental regulation for small and medium-sized enterprises is designed. 展开更多
关键词 Optimal Control Theory small and Medium-Sized Enterprises Water Environment Regulation Contract Mechanism
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Assessing Factors Influencing Solar Energy Adoption among Small and Medium Enterprises in Mzuzu City, Malawi
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作者 Mkhalipie Avenea Beatrice Ke Jiang 《Energy and Power Engineering》 2024年第7期257-284,共28页
One of the many renewable energy sources that offer advantages is solar energy, which also lowers energy prices and promotes environmental sustainability and energy security. Despite these advantages, various barriers... One of the many renewable energy sources that offer advantages is solar energy, which also lowers energy prices and promotes environmental sustainability and energy security. Despite these advantages, various barriers, such as installation costs, have prevented small and medium-sized enterprises from investigating this invention. Malawi has a significant energy shortfall such that most businesses have been hindered from their profit maximization goals. The “Photovoltaic systems” (PV) that transform sunlight into electricity are the subject of this study. This type of solar energy system is situated on the building’s roof and generally produces electricity for businesses and even homes. Solar energy offers a great impact to small and medium enterprises in Mzuzu city with a cost-effective and dependable alternative to energy that has the potential to change the game. Therefore the aim of the study was to identify factors that encourage the adoption of solar energy among small medium enterprises in the city of Mzuzu city. And to identify some of barriers faced when adopting solar energy among small and medium enterprises in the city of Mzuzu. The research approach employed in the study was a survey. A survey is a type of research methodology in which primary data is gathered from a sample using a questionnaire. When information is to be gathered from a wider sample, a survey is employed. A bigger sample size was needed in this study in order to facilitate hypothesis testing. It is advised to apply a logical approach while using the survey. The survey utilized a five-point Likert scale. The study used convenience sampling to select study participants. The sample size in this study was determined using Cochran’s sample size formula. Statistical Package for Social Sciences (SPSS) and Microsoft Excel were used for statistical analysis. About 97.2% of the participants were aware of solar as a source of energy compared to 2.8 % who were unaware. The majority of participants use solar energy for lighting only, seconded by those who use electricity. The least number of participants use solar energy for cooling only. The majority of participants 21.5% indicated partnership and collaboration as the most motivating factor for the adoption of solar energy. This was followed by technical expertise 19.1 % the least number of participants 10.8% expressed that policy and regulatory frameworks were associated with the adoption of solar energy. This study found that there are no statistically significant factors influencing barriers to the adoption of solar energy. The price of solar energy adoption was identified as the least factor associated with the acceptance or rejection of solar energy. Nonetheless, the reasons given by the homes that had embraced solar technology aligned with the findings of other studies. This survey also found that although the public was aware of solar energy, and technology, there were still a number of factors that mattered, especially for non-adopters. 展开更多
关键词 Solar Energy small and Medium Enterprises Solar Energy Adoption
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Small Cell Neuroendocrine Carcinoma of the Vulva: Case Report and Literature Review
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作者 Gabriela Françóes Rostirolla Alessandra Guerra +4 位作者 Maria Carolina Rey Alt Luiza Tesser Dalla Libera Maria Eduarda Appel Binda Márcia Appel Fernando De Marco dos Santos 《Open Journal of Obstetrics and Gynecology》 2024年第2期295-300,共6页
Background: Neuroendocrine neoplasms are those that develop from a neuroendocrine cell. They most commonly affect the lungs, gastrointestinal tract, and pancreas, being rare conditions in the female genital tract. Whe... Background: Neuroendocrine neoplasms are those that develop from a neuroendocrine cell. They most commonly affect the lungs, gastrointestinal tract, and pancreas, being rare conditions in the female genital tract. When present, these neoplasms often manifest with nonspecific signs and symptoms such as pain, itching, swelling, single-focus lesions, bleeding, and enlargement of inguinal lymph nodes, in addition to the presence of progressively enlarging vulvar nodules. Consequently, the diagnostic investigation involves histopathological examination and confirmation through immunohistochemistry. Objective: To present a comprehensive understanding of this rarely studied pathology. The primary objective is to provide valuable insights that could aid in the future development of universally applicable treatment guidelines. Case Presentation: A 57-year-old female, with no prior comorbidities, menopause at 36, who presented with a left vulvar nodule accompanied by intense pain and swelling, later diagnosed with small cell neuroendocrine carcinoma in the vulva. Conclusion: This case report highlights the importance of enhancing our knowledge regarding small cell neuroendocrine carcinoma in the vulva, given its scarcity in medical literature. The information presented here underscores the need for standardized diagnostic and treatment approaches, paving the way for future consensus on managing this uncommon but challenging neoplasm. 展开更多
关键词 Vulvar Neoplasms CARCINOMA small Cell CARCINOMA NEUROENDOCRINE Genital Neoplasms FEMALE Vulvar Diseases
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Characterization of Small-Scale Farmers and Assessment of Their Access to Crop Production Information in Selected Counties of Kenya
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作者 Anastasia Mumbi Wahome John B. K. Kiema +1 位作者 Galcano C. Mulaku Isaac Mukoko 《Agricultural Sciences》 2024年第5期565-589,共25页
Small-scale farming accounts for 78% of total agricultural production in Kenya and contributes to 23.5% of the country’s GDP. Their crop production activities are mostly rainfed subsistence with any surplus being sol... Small-scale farming accounts for 78% of total agricultural production in Kenya and contributes to 23.5% of the country’s GDP. Their crop production activities are mostly rainfed subsistence with any surplus being sold to bring in some income. Timely decisions on farm practices such as farm preparation and planting are critical determinants of the seasonal outcomes. In Kenya, most small-scale farmers have no reliable source of information that would help them make timely and accurate decisions. County governments have extension officers who are mandated with giving farmers advisory services to farmers but they are not able to reach most farmers due to facilitation constraints. The mode and format of sharing information is also critical since it’s important to ensure that it’s timely, well-understood and usable. This study sought to assess access to geospatial derived and other crop production information by farmers in four selected counties of Kenya. Specific objectives were to determine the profile of small-scale farmers in terms of age, education and farm size;to determine the type of information that is made available to them by County and Sub-County extension officers including the format and mode of provision;and to determine if the information provided was useful in terms of accuracy, timeliness and adequacy. The results indicated that over 80% of the farmers were over 35 years of age and over 56% were male. Majority had attained primary education (34%) or secondary education (29%) and most farmers in all the counties grew maize (71%). Notably, fellow farmers were a source of information (71%) with the frequency of sharing information being mostly seasonal (37%) and when information was available (43%). Over 66% of interviewed farmers indicating that they faced challenges while using provided information. The results from the study are insightful and helpful in determining effective ways of providing farmers with useful information to ensure maximum benefits. 展开更多
关键词 small Scale Farmers FARMERS Crop Production Information Services Geospatial Information Information Access
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Immunotherapy for Small Cell Lung Cancer
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作者 Yuxuan Ge Xi Tang 《Journal of Biosciences and Medicines》 2024年第8期320-332,共13页
Small cell lung cancer (SCLC) is a poorly differentiated, highly malignant neuroendocrine tumor characterized by rapid growth, aggressiveness, and easy recurrence. It is usually found in late clinical stage and the op... Small cell lung cancer (SCLC) is a poorly differentiated, highly malignant neuroendocrine tumor characterized by rapid growth, aggressiveness, and easy recurrence. It is usually found in late clinical stage and the opportunity for surgery is lost. Therefore, surgery is often not used in clinical treatment. Although it is sensitive to chemoradiotherapy, it has a high recurrence rate and lacks effective treatment methods at present. Following chemotherapy and radiotherapy, immunotherapy for small cell lung cancer has become the mainstream research direction. Immunotherapy is profoundly changing the approach to cancer treatment due to its tolerable safety profile, sustained treatment response due to the production of immune memory, and effectiveness in a broad patient population. Immunotherapy for small cell lung cancer is one of the effective treatment methods for small cell lung cancer, and relevant studies are not rare, but there are still shortcomings such as intolerance of side effects and inaccurate evaluation of treatment timing. This article reviews the history of immunotherapy, the mechanism of action of immunodrugs, and the current immunodrugs used in the first-line treatment of extensive small cell lung cancer. 展开更多
关键词 small Cell Lung Cancer IMMUNOTHERAPY PD-L1 Inhibitor PD-1 Inhibitor
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Pang Fuwan Uses Yao Medicine to Observe the Therapeutic Effects on the Physical and Mental Symptoms of Patients with Advanced Non-Small Cell Lung Cancer
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作者 Qiuxiang Luo Qiongping Liang Xiaoyan Luo 《Pharmacology & Pharmacy》 2024年第3期62-69,共8页
Objective: Investigate the efficacy and safety of Yao Medicine in the treatment of advanced non-small-cell lung carcinoma, and explore the best therapeutic measure for clinical benefit. Methods: From July 2020 to July... Objective: Investigate the efficacy and safety of Yao Medicine in the treatment of advanced non-small-cell lung carcinoma, and explore the best therapeutic measure for clinical benefit. Methods: From July 2020 to July 2022, 84 patients with advanced non-small-cell lung carcinoma were selected and randomly divided into the Observation Group and control group, and the control group was treated with routine Western medicine, with 42 cases in each group. The activity of daily living (ADL) was assessed before and after treatment, meanwhile, the self-rating depression scale (SDS) and self-rating anxiety SAS (SAS) were used to assess the improvement of a bad mood, and quality of life SF-36 was used to assess the quality of life, to judge the efficacy and safety. Results: The effective rate of observation group was 91.67%. The effective rate of the control group was 76.19%. The effective rate of the observation group was significantly higher than that of the control group (P 0.05). There were no significant differences in the scores of SDS, SAS and quality of life between the two groups before treatment (P > 0.05), and after treatment, the scores of SDS, SAS and quality of life in the two groups were compared with those in the control group (P > 0.05), the scores of VAS, SDS and SAS decreased significantly, while ESCV, angle of straight leg elevation, ADL, physiological score, emotional score, social score and health status score increased significantly, the difference was statistically significant (P 0.05). Conclusion: Yao Medicine can improve the psychosomatic symptoms of patients with advanced non-small-cell lung carcinoma better, with better efficacy and higher safety. 展开更多
关键词 Yao Medicine Non-small-Cell Lung Carcinoma Advanced Stage EFFICACY Physical and Mental
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Analysis and Review of Downregulated Actin Cytoskeletal Proteins in Non-Small Cell Lung Cancer
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作者 Hala M. Abdel Mageed Praveen Sahu Raji Sundararajan 《Journal of Biosciences and Medicines》 2024年第4期89-115,共27页
Actin, a highly conserved protein, plays a dominant role in Non-small cell lung cancer (NSCLC). Late diagnosis and the aggressive nature of NSCLC pose a significant threat. Studying the clinic pathological properties ... Actin, a highly conserved protein, plays a dominant role in Non-small cell lung cancer (NSCLC). Late diagnosis and the aggressive nature of NSCLC pose a significant threat. Studying the clinic pathological properties of NSCLC proteins is a potential alternative for developing treatment strategies. Towards this, 35 downregulated actin cytoskeletal proteins on NSCLC prognosis and treatment were studied by examining their protein-protein interactions, gene ontology enrichment terms, and signaling pathways. Using PubMed, various proteins in NSCLC were identified. The protein-protein interactions and functional associations of these proteins were examined using the STRING database. The focal adhesion signaling pathway was selected from all available KEGG and Wiki pathways because of its role in regulating gene expression, facilitating cell movement and reproduction, and significantly impacting NSCLC. The protein-protein interaction network of the 35 downregulated actin cytoskeleton proteins revealed that ACTG1, ACTR2, ACTR3, ANXA2, ARPC4, FLNA, TLN1, CALD1, MYL6, MYH9, MYH10, TPM1, TPM3, TPM4, PFN1, IQGAP1, MSN, and ZXY exhibited the highest number of interactions. Whereas HSPB1, CTNNA1, KRT17, KRT7, FLNB, SEPT2, and TUBA1B displayed medium interactions, while UTRN, TUBA1B, and DUSP23 had relatively fewer interactions. It was discovered that focal adhesions are critical in connecting membrane receptors with the actin cytoskeleton. In addition, protein kinases, phosphatases, and adapter proteins were identified as key signaling molecules in this process, greatly influencing cell shape, motility, and gene expression. Our analysis shows that the focal adhesion pathway plays a crucial role in NSCLC and is essential for developing effective treatment strategies and improving patient outcomes. 展开更多
关键词 Non-small Cell Lung Cancer NSCLC ACTIN Actin Cytoskeletal Proteins Focal Adhesion KEEG Pathway
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Small Cell Prostate Cancer;Center Review of Two Cases and Testimony of a Rare and Aggressive Disease
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作者 Makama Baje Salihu Haruna Liman +4 位作者 Stephen Yusuf Dauda Suleiman Shaphat Shuaibu Ibrahim Yusuf Aliyu Salihu Isa Sajo Mienda 《Case Reports in Clinical Medicine》 2024年第9期410-417,共8页
Small cell cancers were initially described in the lungs and later found to occur in a wide range of organs of the body, constituted a disease entity that is characterized by an aggrieve path/course and a huge disease... Small cell cancers were initially described in the lungs and later found to occur in a wide range of organs of the body, constituted a disease entity that is characterized by an aggrieve path/course and a huge disease related mortality. They are also called neuroendocrine tumors with peculiar histologic and biologic disease entity. Here we present two cases of small cell cancer of the prostate seen and managed in our facility with focus on their presentation, disease progression and outcome. The first patient was a 72-year-old retired military officer who presented with a progressively painful scrotal swelling of 3-month duration, and scrotal ulceration with contact bleeding of a month duration associated with a foul-smelling discharge. There was also history of progressive weight lost, loss of appetite and constipation. Patient was pale and lethargic on examination with a foul smelling exophytic scrotal mass. Serum PSA was 4 ng/l (within normal limit). Wedge biopsy and trucut prostate biopsy revealed small cell cancer of the prostate. Patient was resuscitated and prepared for chemoradiation, had a single dose of chemotherapy and died before the second dose. Second patient was a 63-year-old farmer who presented with lower urinary tract symptoms, progressive weight loss and constipation of two months duration, a known hypertensive and diabetic who has been regular on his medication. He was lethargic on examination, pale and unable to stand without support. Trucut prostate biopsy shows small cell cancer of the prostate. He was also resuscitated and being prepared for chemoradiation but died before commencement of treatment. 展开更多
关键词 small Cell PROSTATE Cancer Mortality CHEMORADIATION
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Efficacy and Safety of Primary Radiotherapy in Combination with EGFR-TKIs for Non-Small Cell Lung Cancer Harboring EGFR Mutation
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作者 Dongxu Ao Meng Wang +5 位作者 Jinyuan Xie Yang Zhang Xinran Zhang Ya Shu Chenshi Lin Qingqing Ye 《Journal of Biosciences and Medicines》 2024年第9期142-154,共13页
Objective: To evaluate the efficacy and safety of EGFR-TKI with the radiotherapy in EGFR mutant metastatic NSCLC. Methods: Retrospective analysis of 72 patients with stage IV lung cancer with EGFR-sensitive mutation. ... Objective: To evaluate the efficacy and safety of EGFR-TKI with the radiotherapy in EGFR mutant metastatic NSCLC. Methods: Retrospective analysis of 72 patients with stage IV lung cancer with EGFR-sensitive mutation. Patients in the A group were treated with the first-generation EGFR-TKI (Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor) combined with radiotherapy for primary tumors (34 cases). The B group was treated with the first-generation EGFR-TKI alone until the disease progressed (38 cases). PFS, OS, pulmonary infection and hematological toxicity during treatment were commented in both groups. Results: The objective remission rate was 47.1% (16/34) in the A group and 21.1% (8/38) in the B group. There was a significant difference between the two groups. There was no significant difference in hematological toxicity between the A group and the B group. There were 10 patients (29.4%) with degree II pulmonary infection in the A group and 3 patients (7.9%) in the B group. The difference between the two groups was statistically significant, suggesting that the incidence of pneumonia in the A group was higher than that in the B group. The median PFS (Progression-Free Survival)) and OS (Overall Survival) of the A group were significantly longer than those of the B group (16.5 months vs 9 months) and the median OS (36 months vs 19 months). The PFS and OS in the A group were significantly longer than those in the B group. Conclusion: EGFR-TKI combined with primary radiotherapy can significantly prolong the drug resistance time of EGFR mutant metastatic NSCLC. 展开更多
关键词 Non-small Cell Lung Cancer Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor RADIOTHERAPY
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A Review of Cybersecurity Challenges in Small Business: The Imperative for a Future Governance Framework
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作者 Binita Saha Zahid Anwar 《Journal of Information Security》 2024年第1期24-39,共16页
Technological shifts—coupled with infrastructure, techniques, and applications for big data—have created many new opportunities, business models, and industry expansion that benefit entrepreneurs. At the same time, ... Technological shifts—coupled with infrastructure, techniques, and applications for big data—have created many new opportunities, business models, and industry expansion that benefit entrepreneurs. At the same time, however, entrepreneurs are often unprepared for cybersecurity needs—and the policymakers, industry, and nonprofit groups that support them also face technological and knowledge constraints in keeping up with their needs. To improve the ability of entrepreneurship research to understand, identify, and ultimately help address cybersecurity challenges, we conduct a literature review on the state of cybersecurity. The research highlights the necessity for additional investigation to aid small businesses in securing their confidential data and client information from cyber threats, thereby preventing the potential shutdown of the business. 展开更多
关键词 ENTREPRENEURSHIP CYBERSECURITY small and Medium Businesses Data Breach HACKING Security
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Effective Utilization of Government-Provided CTI by Small Businesses within the Defense Industrial Base
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作者 Josiah Dykstra Lawrence A. Gordon +2 位作者 Martin P. Loeb Benjamin Wall Lei Zhou 《Journal of Information Security》 2024年第2期196-217,共22页
There are two broad objectives of the research reported in this paper. First, we assess whether government-provided cyber threat intelligence (CTI) is helpful in preventing, or responding to, cyber-attacks among small... There are two broad objectives of the research reported in this paper. First, we assess whether government-provided cyber threat intelligence (CTI) is helpful in preventing, or responding to, cyber-attacks among small businesses within the U.S. Defense Industrial Base (DIB). Second, we identify ways of improving the effectiveness of government-provided CTI to small businesses within the DIB. Based on a questionnaire-based survey, our findings suggest that government-provided CTI helps businesses within the DIB in preventing, or responding to, cyber-attacks providing a firm is familiar with the CTI. Unfortunately, a large percentage of small firms are not familiar with the government-provided CTI feeds and consequently are not utilizing the CTI. This latter situation is largely due to financial constraints confronting small businesses that prevent firms from having the wherewithal necessary to effectively utilize the government-provided CTI. However, we found a significant positive association between a firm’s familiarity with the government-provided CTI and whether a firm is being periodically reviewed by the Defense Counterintelligence and Security Agency (DCSA) or is compliant with the Cybersecurity Maturity Model Certification (CMMC) program. The findings from our study also show that the participating firms believe that external cyber threats are more likely to be the cause of a future cybersecurity breach than internal cybersecurity threats. Finally, our study found that the portion of the IT budget that small businesses within the DIB spend on cybersecurity-related activities is dependent on the perception that a firm would be the target of an external cyber-attack. 展开更多
关键词 Government-Provided CTI small Businesses Defense Industrial Base
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The Regularity of Solutions to Mixed Boundary Value Problems of Second-Order Elliptic Equations with Small Angles
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作者 Mingyu Wu 《Journal of Applied Mathematics and Physics》 2024年第4期1043-1049,共7页
This paper considers the regularity of solutions to mixed boundary value problems in small-angle regions for elliptic equations. By constructing a specific barrier function, we proved that under the assumption of suff... This paper considers the regularity of solutions to mixed boundary value problems in small-angle regions for elliptic equations. By constructing a specific barrier function, we proved that under the assumption of sufficient regularity of boundary conditions and coefficients, as long as the angle is sufficiently small, the regularity of the solution to the mixed boundary value problem of the second-order elliptic equation can reach any order. 展开更多
关键词 Mixed Boundary Value Problems for Elliptic Equations small-Angle Boundary Value Problems Regularity of Solutions to Elliptic Equations
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基于HS-Small模型临江深基坑降水变形特性分析 被引量:1
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作者 黄建华 李瑞 《水电能源科学》 北大核心 2023年第11期116-120,203,共6页
临江深基坑工程地下水随江水位变化呈现长期水位低、汛期水位高的动态特征,坑内降水导致周围地层渗流场趋于复杂,易引发围护结构破坏、坑底管涌和基坑失稳等工程事故。为此,采用基于HS-Small本构模型对深基坑工程的开挖-降水过程进行模... 临江深基坑工程地下水随江水位变化呈现长期水位低、汛期水位高的动态特征,坑内降水导致周围地层渗流场趋于复杂,易引发围护结构破坏、坑底管涌和基坑失稳等工程事故。为此,采用基于HS-Small本构模型对深基坑工程的开挖-降水过程进行模拟,分析了降水影响因素(降水深度、方式、速率和止水帷幕)对周围环境变形的敏感性及其相互之间的关系,并将分析结果与实测结果进行对比验证。结果表明,随临江深基坑土方开挖和降水进行,基坑坡顶、坑外土体和周边建筑物沉降变形逐渐增大,其中降水对基坑变形影响更明显;分次降水能有效降低周围建筑物和地表的沉降变形;降水深度建议控制在底板以下0.5~2.0 m;降水速率对周围环境沉降总量影响相对较小,但对沉降速率影响较大,当降水速率达到最优值时对基坑稳定性控制有益;止水帷幕嵌入深度超过30 m后对控制周围建筑沉降效果不明显。研究结果可为类似临江深基坑降水工程设计施工提供借鉴和参考。 展开更多
关键词 临江工程 HS-small本构模型 开挖降水 沉降机理 软土地区
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基于轻量化网络与增强多尺度特征融合的绝缘子缺陷检测 被引量:3
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作者 陈奎 刘晓 +2 位作者 贾立娇 方永丽 赵昌新 《高电压技术》 EI CAS CSCD 北大核心 2024年第3期1289-1300,I0025,共13页
随着无人机搭载目标检测算法在输电杆塔绝缘子巡检领域的发展,针对绝缘子缺陷检测速度较低,网络复杂度高且缺陷小目标难以准确检测的问题,提出一种基于轻量化网络与增强多尺度特征融合的YOLOv5-3S-4PH模型进行绝缘子缺陷实时检测。首先... 随着无人机搭载目标检测算法在输电杆塔绝缘子巡检领域的发展,针对绝缘子缺陷检测速度较低,网络复杂度高且缺陷小目标难以准确检测的问题,提出一种基于轻量化网络与增强多尺度特征融合的YOLOv5-3S-4PH模型进行绝缘子缺陷实时检测。首先将重构的ShuffleNetV2-Stem-SPP(3S)网络作为YOLOv5的主干网络,显著减小了网络的参数量和计算量;其次引入针对小目标的增强多尺度特征融合网络以及4个预测头,来增强网络对绝缘子缺陷的感知能力,并结合Mosaic-9数据增强、CIoU损失函数进一步补偿轻量化导致的检测精度损失;最后将其应用到自制绝缘子数据集进行验证。实验结果表明,该文所提出的模型相对于未改进的YOLOv5,全类平均精度提高了3%,检测速度提高了81.8%,参数量、计算量分别压缩了82.4%、67%。因此,所提出的模型更适合部署在无人机平台上进行绝缘子缺陷的实时监测。 展开更多
关键词 绝缘子缺陷检测 YOLOv5 轻量化 ShuffleNetV2网络 小目标检测 无人机
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非小细胞肺癌胸腔镜术后并发症及其对预后的影响 被引量:2
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作者 苏鹏 田子强 +3 位作者 徐延昭 吕会来 李振华 温士旺 《现代肿瘤医学》 CAS 2024年第5期857-862,共6页
目的:探讨非小细胞肺癌患者接受胸腔镜手术后的并发症及其对预后的影响。方法:本研究随机选择2017年06月至2020年06月在我院进行胸腔镜肺癌切除术治疗的102例非小细胞肺癌患者作为研究对象,收集患者临床及随访资料并进行分析。Logistic... 目的:探讨非小细胞肺癌患者接受胸腔镜手术后的并发症及其对预后的影响。方法:本研究随机选择2017年06月至2020年06月在我院进行胸腔镜肺癌切除术治疗的102例非小细胞肺癌患者作为研究对象,收集患者临床及随访资料并进行分析。Logistic回归探讨影响术后并发症或严重并发症的危险因素。以复发为终点进行生存分析,比较不同组别患者之间无复发生存率的差异。结果:在纳入的102例患者中,我们发现,患者年龄(OR=4.009,95%CI:1.209~13.299,P=0.023)、糖尿病(OR=3.515,95%CI:1.045~11.819,P=0.042)、手术时间(OR=1.014,95%CI:1.002~1.026,P=0.020)、术中出血量(OR=1.016,95%CI:1.008~1.025,P<0.001)均为术后并发症的影响因素。同时,手术时间(OR=1.123,95%CI:1.008~1.252,P=0.036)为术后严重并发症的影响因素。并发症组的术后住院时间较无并发症组明显延长(P<0.001)。无并发症患者的无复发生存率显著高于有并发症患者(HR=1.43,95%CI:1.03~1.99,P=0.033),无严重并发症患者的无复发生存率明显高于严重并发症患者(HR=1.61,95%CI:1.15~2.24,P=0.005)。结论:对于接受胸腔镜手术治疗的非小细胞肺癌患者,年龄、糖尿病、手术时间、术中出血量是术后并发症的独立影响因素,且术后并发症可显著降低患者的无复发生存期。 展开更多
关键词 非小细胞肺癌 胸腔镜 并发症 糖尿病 预后
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小流域生态-岩土协同减灾原理与方法初探 被引量:2
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作者 祁生文 刘方翠 +7 位作者 徐梦珍 王学良 薛雷 柳金峰 陈剑刚 黄科翰 孙娟娟 丁昊 《水力发电学报》 CSCD 北大核心 2024年第2期1-14,共14页
随着全球变暖,极端降雨事件增多,导致山区小流域灾害频发,严重威胁人民生命财产安全。小流域防灾减灾形式多样,其中生态工程措施与岩土工程措施相结合协同减灾的方式,不仅能够充分发挥两种措施在不同时间段的减灾作用,而且能够增加整体... 随着全球变暖,极端降雨事件增多,导致山区小流域灾害频发,严重威胁人民生命财产安全。小流域防灾减灾形式多样,其中生态工程措施与岩土工程措施相结合协同减灾的方式,不仅能够充分发挥两种措施在不同时间段的减灾作用,而且能够增加整体减灾功效。目前,受限于生态工程措施与岩土工程措施协同减灾原理不明,评估方法缺乏,导致二者无法有机结合并开展综合减灾效益评估。本文在基于自然解决方案的基础上,提出了山区小流域生态-岩土措施协同减灾的原理,即利用生态工程与岩土工程协作,通过坡面防护和沟道调控,形成稳定阶梯-深潭结构的生态工程-岩土工程措施协同减灾原理。在此基础上,结合地理信息系统和最优化原理,给出基于能量消减的小流域生态工程-岩土工程协同减灾功效的定量化评价方法,为规划、设计、物种选择以及生态工程与岩土工程对策的结合提供依据。 展开更多
关键词 小流域 基于自然解决方案 能量消减 生态-岩土协同减灾
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中国脑小血管病的神经影像学诊断标准及名词标准化定义——来自中国卒中学会的专家共识 被引量:1
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作者 陈玮琪 徐佳洁 +16 位作者 陆瑶 王玲 曹瑾怡 陈鸿宾 郭蕾 吕琰琛 汤晗 王赞 徐非凡 颜庭梦 应云清 仲伟逸 周蓉 陆正齐 程忻 王伊龙 中国卒中学会脑小血管病分会 《中国卒中杂志》 北大核心 2024年第4期375-404,共30页
脑小血管病(small vessel disease,SVD)是一类以脑内小血管受损为主的临床影像综合征,可能会导致卒中、血管性认知障碍、神经心理疾病与其他功能障碍等。自2013年血管性神经病变的影像报告标准(standards for reporting vascular change... 脑小血管病(small vessel disease,SVD)是一类以脑内小血管受损为主的临床影像综合征,可能会导致卒中、血管性认知障碍、神经心理疾病与其他功能障碍等。自2013年血管性神经病变的影像报告标准(standards for reporting vascular changes on neuroimaging,STRIVE)发布以来,SVD的神经影像学特征得到了初步的分类与标准化。然而,在临床实践与科学研究中,对SVD影像特征的认识和应用仍存在诸多不一致和不规范之处。随着对SVD病理生理机制的深入探索与影像技术的不断进步,新的SVD影像特征和定量标志物被相继发现,为SVD的诊断和评估提供了更为全面且精准的信息。在此基础上,STRIVE-2应运而生,以期能更全面地揭示SVD对脑功能与结构的影响。为了规范中国SVD的神经影像学评估和诊断,本共识将在STRIVE-2的基础上,结合中国具体国情,对SVD的神经影像学特征进行深入解读,旨在推动SVD影像学诊断术语的标准化,提高临床诊断的准确性,进一步促进相关领域的研究与进步。 展开更多
关键词 脑小血管病 影像学诊断 定义 专家共识
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银行数字化转型对小微企业自主创新的影响——兼论数字金融的协同作用 被引量:5
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作者 蔡栋梁 王海军 +1 位作者 黄金 黄宇虹 《南开管理评论》 北大核心 2024年第3期39-49,I0007,I0008,共13页
银行数字化转型提高了金融服务质量与效率,这能否缓解实体经济融资约束,助力小微企业牵住自主创新的“牛鼻子”?本文构建理论模型刻画银行数字化转型对小微企业自主创新的影响,并采用爬虫技术获得超过18万条有关商业银行报道的新闻文本... 银行数字化转型提高了金融服务质量与效率,这能否缓解实体经济融资约束,助力小微企业牵住自主创新的“牛鼻子”?本文构建理论模型刻画银行数字化转型对小微企业自主创新的影响,并采用爬虫技术获得超过18万条有关商业银行报道的新闻文本,创新地构造了地级市层面的银行数字化转型指数,将中国小微企业调查(CM ES)数据和银行数字化转型指数相匹配,实证检验银行数字化转型对小微企业自主创新的影响及其机制,并据此分析银行数字化转型与数字金融的协同作用。研究发现,银行数字化转型通过缓解企业融资约束的中介机制,显著驱动了小微企业自主创新。进一步研究发现,银行数字化转型与数字金融在驱动小微企业自主创新方面具有协同效应,数字金融水平越高,银行数字化转型的创新驱动效应越强。本文将制度环境划分为产权保护、产研结合、政策环境,通过异质性分析发现,在知识产权保护环境较好、社会平台协作度较高及经济政策不确定性较小的地区,银行数字化转型对小微企业自主创新的驱动作用更为显著。本研究为赋能银行数字化转型战略提供了支持证据,也为解决实体经济融资难问题、驱动自主创新、促进经济高质量发展提供了解决方案。 展开更多
关键词 银行数字化转型 小微企业 自主创新 数字金融 融资约束
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血清小而密低密度脂蛋白胆固醇和总抗氧化能力水平与脑梗死患者认知功能障碍的相关性分析 被引量:2
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作者 马娟 郝晨光 +1 位作者 何丹 马建华 《江苏大学学报(医学版)》 CAS 2024年第2期161-165,175,共6页
目的:探究脑梗死患者血清小而密低密度脂蛋白胆固醇(small dense low-density lipoprotein cholesterol, sdLDL-C)和总抗氧化能力(total antioxidant capacity, T-AOC)水平变化及其与认知功能障碍发生的关系。方法:选择148例脑梗死患者... 目的:探究脑梗死患者血清小而密低密度脂蛋白胆固醇(small dense low-density lipoprotein cholesterol, sdLDL-C)和总抗氧化能力(total antioxidant capacity, T-AOC)水平变化及其与认知功能障碍发生的关系。方法:选择148例脑梗死患者,依据发病后7 d是否出现认知功能障碍,分为非障碍组(n=77)和障碍组(n=71);分别采用过氧化氢酶法和比色法测定两组血清sdLDL-C和T-AOC水平,并进行比较;Pearson相关系数法分析脑梗死患者血清sdLDL-C、T-AOC水平与蒙特利尔认知评估(MoCA)评分相关性;二元Logistic回归分析影响脑梗死患者认知功能障碍发生的危险因素。结果:与非障碍组相比,障碍组血清sdLDL-C水平明显升高(P<0.05),T-AOC水平明显降低(P<0.05)。相关性分析显示,血清sdLDL-C水平与MoCA评分呈负相关(r=-0.516,P<0.05),T-AOC水平与MoCA评分呈正相关(r=0.446,P<0.05)。Logistic回归分析显示,高血压、糖尿病、病情严重程度、血清sdLDL-C和T-AOC是脑梗死患者认知功能障碍发生的独立影响因素(P<0.05)。结论:脑梗死患者血清sdLDL-C水平升高,T-AOC水平降低,二者是影响脑梗死患者并发认知功能障碍的独立影响因素。 展开更多
关键词 脑梗死 认知功能障碍 小而密低密度脂蛋白胆固醇 总抗氧化能力
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基于改进YOLOv5s的小目标检测算法 被引量:5
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作者 贵向泉 秦庆松 孔令旺 《计算机工程与设计》 北大核心 2024年第4期1134-1140,共7页
针对当前主流目标检测算法对图像中远距离小目标产生的漏检、误检等问题,提出一种改进YOLOv5s的小目标检测算法。在模型训练过程中,通过引入Focal-EIOU定位损失函数,加强边界框的定位精度;在骨干网络中,通过添加小目标检测层,提高小目... 针对当前主流目标检测算法对图像中远距离小目标产生的漏检、误检等问题,提出一种改进YOLOv5s的小目标检测算法。在模型训练过程中,通过引入Focal-EIOU定位损失函数,加强边界框的定位精度;在骨干网络中,通过添加小目标检测层,提高小目标的检测精度;在Neck结构中,通过优化上采样算子和添加注意力机制,加强小目标的特征信息。实验结果表明,改进后的算法在VisDrone数据集上与YOLOv5s算法相比,mAP@small提高了3.2%,且检测速度满足实时性的要求,能够很好地应用于小目标检测任务中。 展开更多
关键词 YOLOv5s算法 小目标检测 损失函数 上采样算子 骨干网络 注意力机制 特征信息
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