The mechanism underlying body weight support treadmill training in elderly hemiplegic stroke patients is largely unknown. This study aimed to elucidate the changes of cortical blood flow in seven elderly patients with...The mechanism underlying body weight support treadmill training in elderly hemiplegic stroke patients is largely unknown. This study aimed to elucidate the changes of cortical blood flow in seven elderly patients with post-stroke hemiplegia before and after body weight support treadmill training by semi-quantitative analysis of regional cerebral blood flow assessed by single photon emission computed tomography. Body weight support treadmill training for 6 months was effective in improving cerebral blood flow and promoting the walking speed and balance recovery in elderly patients with post-stroke hemiplegia.展开更多
Walking is the most basic and essential part of the activities of daily living. To enable the elderly and non-ambulatory gait-impaired patients, the repetitive practice of this task, a novel gait training robot(GTR) w...Walking is the most basic and essential part of the activities of daily living. To enable the elderly and non-ambulatory gait-impaired patients, the repetitive practice of this task, a novel gait training robot(GTR) was designed followed the end-effector principle, and an active partial body weight support(PBWS) system was introduced to facilitate successful gait training. For successful establishment of a walking gait on the GTR with PBWS, the motion laws of the GTR were planned to enable the phase distribution relationships of the cycle step, and the center of gravity(COG) trajectory of the human body during gait training on the GTR was measured. A coordinated control strategy was proposed based on the impedance control principle. A robotic prototype was developed as a platform for evaluating the design concepts and control strategies. Preliminary gait training with a healthy subject was implemented by the robotic-assisted gait training system and the experimental results are encouraging.展开更多
The aim of this study was to compare the effects of two types of high intensity interval training (HIIT) on body mass and physiological indexes in inactive female students. 27 inactive female students (mean age 24....The aim of this study was to compare the effects of two types of high intensity interval training (HIIT) on body mass and physiological indexes in inactive female students. 27 inactive female students (mean age 24.81 ±0.66 yr, height 162.09 ±0.67 cm, weight 59.41 ±0.33 kg) were voluntarily selected and randomly assigned to three groups (each group = 9 subjects) of high intensity interval training (type I), high intensity interval training (type 2) and control. HIIT (type 1) (8 seconds of sprint running and 12 seconds of active recovery) was performed for 4 weeks, 3 sessions per week, 6-9 min. per session with above 90% maxHR. HIlT (type 2) (40-m shuttle run test with maximum speed) was performed with above 90% max HR while the control group did not participate in any training. Data analysis with dependent t test showed that HIIT (type 1) and HIlT (type 2) significantly increased VO2max while they decreased fat percentage and BMI. The intergroup data were analyzed by one-way ANOVA at P 〈 0.05. The results showed a significant difference among HIlT (type 1), HIIT (type 2) and control groups in VO2max, BMI and fat percentage.展开更多
目的:通过Meta分析综合定量评价低容量高强度间歇训练对预防肥胖或超重人群心血管疾病的效果,进一步验证低容量高强度间歇训练在肥胖等特殊人群中应用的可行性。方法:在中国知网、PubMed、Web of Science、Cochrane Library和EBSCO-SPO...目的:通过Meta分析综合定量评价低容量高强度间歇训练对预防肥胖或超重人群心血管疾病的效果,进一步验证低容量高强度间歇训练在肥胖等特殊人群中应用的可行性。方法:在中国知网、PubMed、Web of Science、Cochrane Library和EBSCO-SPORTD运动科学全文数据库检索关于低容量高强度间歇训练相关研究的随机对照试验文献,检索时限为各数据库建库至2024年2月。由2名研究人员对所纳入的研究进行筛选、质量评价和数据提取,采用RevMan 5.4和Stata 17.0软件对结局指标进行Meta分析,包括合并效应量、亚组分析、Leave-One-Out敏感性分析以及发表Egger检验和绘制漏斗图。该方案已在国际系统综述前瞻性注册中心注册(CRD42024534409)。结果:①最终筛选纳入符合要求的13项随机对照试验,共包含349例受试者,纳入文献整体质量较高。②低容量高强度间歇训练干预对心肺适能(SMD=-0.65,95%CI:-0.87至-0.43,P<0.05)、收缩压(SMD=0.38,95%CI:0.11-0.65,P<0.05)、舒张压(SMD=0.42,95%CI:0.15-0.68,P<0.05)和体脂百分比(SMD=0.25,95%CI:0.02-0.49,P<0.05)4项指标具有改善效果。③低容量高强度间歇训练与中等强度持续训练相比在改善超重或肥胖人群心肺适能、收缩压、舒张压、体脂百分比、标准体质量、体质量指数、高密度脂蛋白、低密度脂蛋白和总胆固醇指标方面干预效果相似(P>0.05),但在改善三酰甘油效果方面中等强度持续训练优于低容量高强度间歇训练(SMD=-0.30,95%CI:-0.57至-0.02,P<0.05)。④亚组分析结果进一步显示,低容量高强度间歇训练和中等强度持续训练干预对各项指标的改善效果相似。结论:当前证据表明,低容量高强度间歇训练可以有效提升超重或肥胖人群的心肺适应能力以及促进减脂和血压调控,且改善效果与中等强度持续训练相似。短时间的低容量高强度间歇训练相比于长时间的中等强度持续训练更具有时间效益。建议未来通过更多研究确定适用于超重或肥胖人群最佳的低容量高强度间歇训练运动处方。展开更多
Prostate cancer (PCa) is the most common visceral malignancy in men with androgen deprivation therapy (ADT) the preferred therapy to suppress testosterone production and hence tumor growth. Despite its effectivene...Prostate cancer (PCa) is the most common visceral malignancy in men with androgen deprivation therapy (ADT) the preferred therapy to suppress testosterone production and hence tumor growth. Despite its effectiveness in lowering testosterone, ADT is associated with side effects including loss of muscle mass, diminished muscle strength, decrements in physical performance, earlier fatigue and declining quality of life. This review reports a survey of the literature with a focus on changes in muscle strength, physical function and body composition, due to short-term and long-term ADT. Studies in these areas are sparse, especially well-controlled, prospective randomized trials. Cross-sectional and longitudinal data (up to 2 years) for men with PCa treated with ADT as well as patients with PCa not receiving ADT and age-matched healthy men are presented when available. Based on limited longitudinal data, the adverse effects of ADT on muscle function, physical performance and body composition occur shortly after the onset of ADT and tend to persist and worsen over time. Exercise training is a safe and effective intervention for mitigating these changes and initial guidelines for exercise program design for men with PCa have been published by the American College of Sports Medicine. Disparities in study duration, types of studies and other patient-specific variables such as time since diagnosis, cancer stage and comorbidities may all affect an understanding of the influence of ADT on health, physical performance and mortality.展开更多
In view of the problem that it's difficult to accurately grasp the influence range and transmission path of the vehicle top design requirements on the underlying design parameters. Applying directed-weighted complex ...In view of the problem that it's difficult to accurately grasp the influence range and transmission path of the vehicle top design requirements on the underlying design parameters. Applying directed-weighted complex network to product parameter model is an important method that can clarify the relationships between product parameters and establish the top-down design of a product. The relationships of the product parameters of each node are calculated via a simple path searching algorithm, and the main design parameters are extracted by analysis and comparison. A uniform definition of the index formula for out-in degree can be provided based on the analysis of out- in-degree width and depth and control strength of train carriage body parameters. Vehicle gauge, axle load, crosswind and other parameters with higher values of the out-degree index are the most important boundary condi- tions; the most considerable performance indices are the parameters that have higher values of the out-in-degree index including torsional stiffness, maximum testing speed, service life of the vehicle, and so on; the main design parameters contain train carriage body weight, train weight per extended metre, train height and other parameters with higher values of the in-degree index. The network not only provides theoretical guidance for exploring the relationship of design parameters, but also further enriches the appli- cation of forward design method to high-speed trains.展开更多
BACKGROUND Knee joint pain and stiffness are the two main symptoms of knee osteoarthritis(OA)and thus restrict a patient’s activities,such as walking and walking up and downstairs.The lower body positive pressure(LBP...BACKGROUND Knee joint pain and stiffness are the two main symptoms of knee osteoarthritis(OA)and thus restrict a patient’s activities,such as walking and walking up and downstairs.The lower body positive pressure(LBPP)treadmill as one of the emerging body weight support system devices brings new hope for exerciserelated rehabilitation for knee OA patients.AIM To investigate the biomechanical effects and the subjective clinical assessment of LBPP treadmill walking exercise when compared with conventional therapy in mild to moderate knee OA patients.METHODS Eighteen patients with mild-to-moderate knee OA were recruited in this randomized controlled trial(RCT)study.The eligible knee OA patients were randomly assigned to two groups:LBPP and control groups.The patients in the LBPP group performed an LBPP walking training program for 30 min/session per day,6 d per week for 2 wk whereas the patients in the control group performed walking on the ground for the same amount.All patients underwent clinical assessments and three-dimensional gait analysis at pre-and 2-wk post-treatment.RESULTS The Western Ontario and McMaster Universities Arthritis Index and visual analog scale scores in both the LBPP group and control group were found to decrease significantly at the post-treatment point than the pre-treatment point(LBPP:70.25±13.93 vs 40.50±11.86;3.88±0.99 vs 1.63±0.52;control:69.20±8.88 vs 48.10±8.67;3.80±0.79 vs 2.60±0.70,P<0.001).Moreover,compared with the control group,the LBPP group showed more improvements in walking speed(P=0.007),stride length(P=0.037),and knee range of motion(P=0.048)during walking,which represented more improvement in walking ability.CONCLUSION The results of our RCT study showed that the LBPP group has a greater effect on improving gait parameters than the conventional group,although there was no significant advantage in clinical assessment.This finding indicates that LBPP treadmill walking training might be an effective approach for alleviating pain symptoms and improving lower extremity locomotion in mild to moderate knee OA patients.展开更多
The aim of the study was to investigate associations between psychological and biological changes due to resistance training in people with impaired glucose tolerance (IGT). Subjects were randomized into maximal (MRT)...The aim of the study was to investigate associations between psychological and biological changes due to resistance training in people with impaired glucose tolerance (IGT). Subjects were randomized into maximal (MRT) versus endurance resistance training (ERT) groups. Intervention periods lasted four months. All subjects had blood work that suggested IGT at the initial screening. The ERT acted as a wait-list control group when the MRT performed their training. Baseline scores on general life satisfaction (LISAT) and sense of humor (SHQ-6: a positive coping resources) were obtained. Potential differences between groups (types of intervention and intervention versus control) were investigated by analysis of variance (one-way ANOVA). Correlations were calculated in each group to estimate the degree of covariance between biological and psychological changes from pre- to post-intervention by Pearson and Spearman coefficients. Sense of humor tended to be correlated with a positive reduction of insulin following MRT as well as with reduction in body fat following ERT. Differences across the intervention groups in changes from pre- to post-training in biological variables (glucose, insulin, muscle mass, and corrected percentage of fat) as well as psychological variables (general life satisfaction and sense of humor) were not significant, whereas differences in BMI and weight were significant. By investigating the intervention groups separately in comparison to the control group, the MRT revealed significant improvement by reduction in insulin, percentage of fat, BMI and weight. The ERT caused significant improvements for insulin and percentage of fat, while general life satisfaction had a significant negative development.展开更多
The safety production is critical to stable development of Chinese electric power industry. With the development of electric power enterprises, the requirements of its employees are also becoming higher and higher. In...The safety production is critical to stable development of Chinese electric power industry. With the development of electric power enterprises, the requirements of its employees are also becoming higher and higher. In this paper, an optical motion capture system based on the virtual reality technology is proposed to meet the requirements of the power enterprise for the qualified business ability. Electric power equipment, power equipment model entitative operating environment and the human model are established by electric power simulation unit, ZigBee technology and OpenGL graphics library. The problem of missing feature points is solved by applying the human model driven algorithm and the Kalman filtering algorithm. The experimental results show that it is more accurate to use Kalman filtering algorithm to extract the feature point in tracking process of actual motion capture and real-time animation display. The average absolute error of 3D coordinates is 1.61 mm and the average relative error is 2.23%. The system can improve trainees’ sense of experience and immersion.展开更多
文摘The mechanism underlying body weight support treadmill training in elderly hemiplegic stroke patients is largely unknown. This study aimed to elucidate the changes of cortical blood flow in seven elderly patients with post-stroke hemiplegia before and after body weight support treadmill training by semi-quantitative analysis of regional cerebral blood flow assessed by single photon emission computed tomography. Body weight support treadmill training for 6 months was effective in improving cerebral blood flow and promoting the walking speed and balance recovery in elderly patients with post-stroke hemiplegia.
基金Project(61175128) supported by the National Natural Science Foundation of ChinaProject(2008AA040203) supported by the National High Technology Research and Development Program of China
文摘Walking is the most basic and essential part of the activities of daily living. To enable the elderly and non-ambulatory gait-impaired patients, the repetitive practice of this task, a novel gait training robot(GTR) was designed followed the end-effector principle, and an active partial body weight support(PBWS) system was introduced to facilitate successful gait training. For successful establishment of a walking gait on the GTR with PBWS, the motion laws of the GTR were planned to enable the phase distribution relationships of the cycle step, and the center of gravity(COG) trajectory of the human body during gait training on the GTR was measured. A coordinated control strategy was proposed based on the impedance control principle. A robotic prototype was developed as a platform for evaluating the design concepts and control strategies. Preliminary gait training with a healthy subject was implemented by the robotic-assisted gait training system and the experimental results are encouraging.
文摘The aim of this study was to compare the effects of two types of high intensity interval training (HIIT) on body mass and physiological indexes in inactive female students. 27 inactive female students (mean age 24.81 ±0.66 yr, height 162.09 ±0.67 cm, weight 59.41 ±0.33 kg) were voluntarily selected and randomly assigned to three groups (each group = 9 subjects) of high intensity interval training (type I), high intensity interval training (type 2) and control. HIIT (type 1) (8 seconds of sprint running and 12 seconds of active recovery) was performed for 4 weeks, 3 sessions per week, 6-9 min. per session with above 90% maxHR. HIlT (type 2) (40-m shuttle run test with maximum speed) was performed with above 90% max HR while the control group did not participate in any training. Data analysis with dependent t test showed that HIIT (type 1) and HIlT (type 2) significantly increased VO2max while they decreased fat percentage and BMI. The intergroup data were analyzed by one-way ANOVA at P 〈 0.05. The results showed a significant difference among HIlT (type 1), HIIT (type 2) and control groups in VO2max, BMI and fat percentage.
文摘Prostate cancer (PCa) is the most common visceral malignancy in men with androgen deprivation therapy (ADT) the preferred therapy to suppress testosterone production and hence tumor growth. Despite its effectiveness in lowering testosterone, ADT is associated with side effects including loss of muscle mass, diminished muscle strength, decrements in physical performance, earlier fatigue and declining quality of life. This review reports a survey of the literature with a focus on changes in muscle strength, physical function and body composition, due to short-term and long-term ADT. Studies in these areas are sparse, especially well-controlled, prospective randomized trials. Cross-sectional and longitudinal data (up to 2 years) for men with PCa treated with ADT as well as patients with PCa not receiving ADT and age-matched healthy men are presented when available. Based on limited longitudinal data, the adverse effects of ADT on muscle function, physical performance and body composition occur shortly after the onset of ADT and tend to persist and worsen over time. Exercise training is a safe and effective intervention for mitigating these changes and initial guidelines for exercise program design for men with PCa have been published by the American College of Sports Medicine. Disparities in study duration, types of studies and other patient-specific variables such as time since diagnosis, cancer stage and comorbidities may all affect an understanding of the influence of ADT on health, physical performance and mortality.
基金Supported by National Natural Science Foundation of China(Grant Nos51275432,51505390)Sichuan Provincial Application Foundation Projects of China(Grant No.2016JY0098)Independent Research Project of TPL(Grant No.TPL1501)
文摘In view of the problem that it's difficult to accurately grasp the influence range and transmission path of the vehicle top design requirements on the underlying design parameters. Applying directed-weighted complex network to product parameter model is an important method that can clarify the relationships between product parameters and establish the top-down design of a product. The relationships of the product parameters of each node are calculated via a simple path searching algorithm, and the main design parameters are extracted by analysis and comparison. A uniform definition of the index formula for out-in degree can be provided based on the analysis of out- in-degree width and depth and control strength of train carriage body parameters. Vehicle gauge, axle load, crosswind and other parameters with higher values of the out-degree index are the most important boundary condi- tions; the most considerable performance indices are the parameters that have higher values of the out-in-degree index including torsional stiffness, maximum testing speed, service life of the vehicle, and so on; the main design parameters contain train carriage body weight, train weight per extended metre, train height and other parameters with higher values of the in-degree index. The network not only provides theoretical guidance for exploring the relationship of design parameters, but also further enriches the appli- cation of forward design method to high-speed trains.
基金the Medical Ethics Association of the Fifth Affiliated Hospital of Guangzhou Medical University(No.KY01-2018-10-18).
文摘BACKGROUND Knee joint pain and stiffness are the two main symptoms of knee osteoarthritis(OA)and thus restrict a patient’s activities,such as walking and walking up and downstairs.The lower body positive pressure(LBPP)treadmill as one of the emerging body weight support system devices brings new hope for exerciserelated rehabilitation for knee OA patients.AIM To investigate the biomechanical effects and the subjective clinical assessment of LBPP treadmill walking exercise when compared with conventional therapy in mild to moderate knee OA patients.METHODS Eighteen patients with mild-to-moderate knee OA were recruited in this randomized controlled trial(RCT)study.The eligible knee OA patients were randomly assigned to two groups:LBPP and control groups.The patients in the LBPP group performed an LBPP walking training program for 30 min/session per day,6 d per week for 2 wk whereas the patients in the control group performed walking on the ground for the same amount.All patients underwent clinical assessments and three-dimensional gait analysis at pre-and 2-wk post-treatment.RESULTS The Western Ontario and McMaster Universities Arthritis Index and visual analog scale scores in both the LBPP group and control group were found to decrease significantly at the post-treatment point than the pre-treatment point(LBPP:70.25±13.93 vs 40.50±11.86;3.88±0.99 vs 1.63±0.52;control:69.20±8.88 vs 48.10±8.67;3.80±0.79 vs 2.60±0.70,P<0.001).Moreover,compared with the control group,the LBPP group showed more improvements in walking speed(P=0.007),stride length(P=0.037),and knee range of motion(P=0.048)during walking,which represented more improvement in walking ability.CONCLUSION The results of our RCT study showed that the LBPP group has a greater effect on improving gait parameters than the conventional group,although there was no significant advantage in clinical assessment.This finding indicates that LBPP treadmill walking training might be an effective approach for alleviating pain symptoms and improving lower extremity locomotion in mild to moderate knee OA patients.
文摘The aim of the study was to investigate associations between psychological and biological changes due to resistance training in people with impaired glucose tolerance (IGT). Subjects were randomized into maximal (MRT) versus endurance resistance training (ERT) groups. Intervention periods lasted four months. All subjects had blood work that suggested IGT at the initial screening. The ERT acted as a wait-list control group when the MRT performed their training. Baseline scores on general life satisfaction (LISAT) and sense of humor (SHQ-6: a positive coping resources) were obtained. Potential differences between groups (types of intervention and intervention versus control) were investigated by analysis of variance (one-way ANOVA). Correlations were calculated in each group to estimate the degree of covariance between biological and psychological changes from pre- to post-intervention by Pearson and Spearman coefficients. Sense of humor tended to be correlated with a positive reduction of insulin following MRT as well as with reduction in body fat following ERT. Differences across the intervention groups in changes from pre- to post-training in biological variables (glucose, insulin, muscle mass, and corrected percentage of fat) as well as psychological variables (general life satisfaction and sense of humor) were not significant, whereas differences in BMI and weight were significant. By investigating the intervention groups separately in comparison to the control group, the MRT revealed significant improvement by reduction in insulin, percentage of fat, BMI and weight. The ERT caused significant improvements for insulin and percentage of fat, while general life satisfaction had a significant negative development.
文摘The safety production is critical to stable development of Chinese electric power industry. With the development of electric power enterprises, the requirements of its employees are also becoming higher and higher. In this paper, an optical motion capture system based on the virtual reality technology is proposed to meet the requirements of the power enterprise for the qualified business ability. Electric power equipment, power equipment model entitative operating environment and the human model are established by electric power simulation unit, ZigBee technology and OpenGL graphics library. The problem of missing feature points is solved by applying the human model driven algorithm and the Kalman filtering algorithm. The experimental results show that it is more accurate to use Kalman filtering algorithm to extract the feature point in tracking process of actual motion capture and real-time animation display. The average absolute error of 3D coordinates is 1.61 mm and the average relative error is 2.23%. The system can improve trainees’ sense of experience and immersion.