Objective： To observe the clinical efficacy of Qingqiao Capsule （清窍胶囊, QQC） in treating patients with secretory otitis media （SOM）. Methods： A total of 90 patients were randomly assigned into the treated gro...Objective： To observe the clinical efficacy of Qingqiao Capsule （清窍胶囊, QQC） in treating patients with secretory otitis media （SOM）. Methods： A total of 90 patients were randomly assigned into the treated group （n：45） and the control group （n=45）. Patients in the treated group were administrated with QQC, 5 capsules each time, 3 times a day for totally 10-14 days, and those in the control group were given per os cefaclor capsules 0.5g each time for adult, 3 times a day, or 20mg/（kg·d） for children, for 10-14 days. The therapeutic efficacy of treatment on the patients was observed and compared after treatment and followed up for 3-6 months. Results： （1） The clinical efficacy in the treated group was superior to that in the control group with significant statistical difference （P〈0.01）; （2） Comparison of the efficacies in patients of three different TCM syndrome types （the external pathogenic wind invasion caused auditory orifice stuffiness type, the Gan-Dan damp-heat steaming up auditory orifice type and the Pi-deficiency dysfunction induced dirty dampness blocking ear type） showed no statistically significant difference（P〉0.05）; （3） The vanishing rate and time needed of the main symptoms and signs in the treated group were superior to those in the control group on ear muffle, tinnitus, hearing impairment, hydrotypanum, pure tone threshold and abnormal tongue figure, and the difference was statistically significant （P〈0.05 or P〈0.01）, only those of earache, otopiesis and abnornal pulse figure were insignificantly different between the two groups （P〉0.05）. Conclusion： QQC is an effective Chinese composite medicine on patients with SOM, and shows no obvious adverse reaction.展开更多
目的观察鼻内镜下咽鼓管置管联合鼓室中药液冲洗治疗慢性分泌性中耳炎（CSOM）的治疗效果。方法将2012年9月-2014年3月期间就诊的80例CSOM患者随机分成2组。实验组40例（61耳）行经鼻内镜下咽鼓管置管联合鼓室清窍汤冲洗,每次2 m L,4~7 ...目的观察鼻内镜下咽鼓管置管联合鼓室中药液冲洗治疗慢性分泌性中耳炎（CSOM）的治疗效果。方法将2012年9月-2014年3月期间就诊的80例CSOM患者随机分成2组。实验组40例（61耳）行经鼻内镜下咽鼓管置管联合鼓室清窍汤冲洗,每次2 m L,4~7 d。对照组40例（59耳）行鼓膜切开置管,置入管通常6~8周后取出或自行掉落。术后随访6月,观察2组疗效。结果实验组治愈率为81.97%,总有效率为95.08%,优于对照组（64.41%、83.05%）,P〈0.05。实验组并发症发生率为9.84%,低于对照组（28.81%）,P〈0.05。实验组复发率为6.56%,低于对照组（20.34%）,P〈0.05。结论鼻内镜下咽鼓管置管联合鼓室清窍汤冲洗治疗慢性分泌性中耳炎,创伤小、疗效确切、副反应少、复发率低,值得临床推广。展开更多
文摘Objective： To observe the clinical efficacy of Qingqiao Capsule （清窍胶囊, QQC） in treating patients with secretory otitis media （SOM）. Methods： A total of 90 patients were randomly assigned into the treated group （n：45） and the control group （n=45）. Patients in the treated group were administrated with QQC, 5 capsules each time, 3 times a day for totally 10-14 days, and those in the control group were given per os cefaclor capsules 0.5g each time for adult, 3 times a day, or 20mg/（kg·d） for children, for 10-14 days. The therapeutic efficacy of treatment on the patients was observed and compared after treatment and followed up for 3-6 months. Results： （1） The clinical efficacy in the treated group was superior to that in the control group with significant statistical difference （P〈0.01）; （2） Comparison of the efficacies in patients of three different TCM syndrome types （the external pathogenic wind invasion caused auditory orifice stuffiness type, the Gan-Dan damp-heat steaming up auditory orifice type and the Pi-deficiency dysfunction induced dirty dampness blocking ear type） showed no statistically significant difference（P〉0.05）; （3） The vanishing rate and time needed of the main symptoms and signs in the treated group were superior to those in the control group on ear muffle, tinnitus, hearing impairment, hydrotypanum, pure tone threshold and abnormal tongue figure, and the difference was statistically significant （P〈0.05 or P〈0.01）, only those of earache, otopiesis and abnornal pulse figure were insignificantly different between the two groups （P〉0.05）. Conclusion： QQC is an effective Chinese composite medicine on patients with SOM, and shows no obvious adverse reaction.
文摘目的观察鼻内镜下咽鼓管置管联合鼓室中药液冲洗治疗慢性分泌性中耳炎（CSOM）的治疗效果。方法将2012年9月-2014年3月期间就诊的80例CSOM患者随机分成2组。实验组40例（61耳）行经鼻内镜下咽鼓管置管联合鼓室清窍汤冲洗,每次2 m L,4~7 d。对照组40例（59耳）行鼓膜切开置管,置入管通常6~8周后取出或自行掉落。术后随访6月,观察2组疗效。结果实验组治愈率为81.97%,总有效率为95.08%,优于对照组（64.41%、83.05%）,P〈0.05。实验组并发症发生率为9.84%,低于对照组（28.81%）,P〈0.05。实验组复发率为6.56%,低于对照组（20.34%）,P〈0.05。结论鼻内镜下咽鼓管置管联合鼓室清窍汤冲洗治疗慢性分泌性中耳炎,创伤小、疗效确切、副反应少、复发率低,值得临床推广。
