Effect of Mouth Opening Training Stick Combined with Oral Massage on Mouth Opening Difficulty in Head and Neck Cancer Patients after Treatment

Objective: To study the application effect of mouth-opening training sticks combined with oral massage on patients with mouth-opening difficulty after treatment for head and neck cancer. Methods: Using convenient sampling, 60 patients with mouth-opening difficulty after treatment for head and neck cancer admitted to the Oncology Department from February 2022 to October 2023 were selected for a 2-week exercise and nursing program. The patients were divided into a control group (February 1, 2022 to November 30, 2022) and an observation group (December 1, 2022 to October 31, 2023), with 30 patients in each group. The control group underwent routine mouth-opening functional exercises combined with cork for oral support training, while the observation group underwent routine mouth-opening functional exercises combined with oral massage and mouth-opening training sticks for oral support training. The mouth-opening degree, mouth-opening difficulty level, comfort level, compliance, and quality of life were observed in both groups. Results: Before the intervention, there were no statistically significant differences in mouth-opening degree and mouth-opening difficulty level between the two groups (P > 0.05). After the intervention, the mouth-opening degree, mouth-opening difficulty level, oral comfort level, compliance, and QLICP-HN scores in the observation group were all better than those in the control group, with statistically significant differences (P < 0.05). Conclusion: The combination of mouth-opening training sticks and oral massage with mouth-opening functional exercises can effectively improve the degree of mouth-opening difficulty, enhance oral comfort, increase compliance with mouth-opening exercises, and improve quality of life.

FURTHER OPENING- UP IS KEY FOR CHINA’S HIGH-QUALITY DEVELOPMENT

The Central Economic Work Conference was held in Beijing from December 11 to 12.The conference discussed the plans,prospects and challenges for China’s economy heading into 2024,as well as evaluating the events of this year.It goes without saying that 2023 has been a challenging year for countries around the world as the global context has been unsatisfactory.Various geopolitical tensions have created a rise in uncertainties which have led to reduced growth worldwide and sent many economies into stagnation.In light of the critical factors affecting the stability of the global economy,China’s primary economic goal corresponds with the promotion and sustaining of free trade.

National Image Construction from the Perspective of Multimodal Metaphor-A Case Study of the Opening Ceremony of the Beijing Winter Olympics

The national image is a comprehensive concept with a distinct political feature,including the international image presented to the outside world,and also encompassing the national identity of the people.With the development of globalization,international cultural communication has become a crucial part of shaping the national image,and the opening ceremony of the Beijing Winter Olympics has become an important opportunity for China to showcase its national image to the world in the post-pandemic era.Based on Forceville’s multimodal metaphor theory,this paper examines the metaphorical phenomena contained in the performance and their functions,effects,and purposes in the construction of the national image.It is found that there are many scenes,images,and narratives in the opening ceremony,including war metaphor,competition metaphor,personification metaphor,and other conceptual metaphors.The focus of this paper is on multimodal metaphor in a broad sense,mainly encompassing auditory and visual modes.Through the use of these multimodal metaphors,the opening ceremony of the Winter Olympics builds an image of a vibrant,peace-loving,and responsible country,which not only demonstrates China’s cultural self-confidence,but also expresses the Chinese people’s beautiful vision for the early reunification of the motherland.

CIIE to Promote High-Level Opening Up

The 7th China International Import Expo(CIIE),scheduled to be held in Shanghai from 5 to 10 November,will play a part in promoting highlevel opening up,said Tang Wenhong,China’s assistant minister of commerce,at a press conference on 23 October.The CIIE serves to showcase China’s major opening-up measures and confidence,to share China’s new development opportunities with other countries.

High complex anal fistula managed by the modified transanal opening of the intersphincteric space via the inter-sphincteric approach:A case report

BACKGROUND High complex anal fistulas are epithelialized tunnels,with the main fistula piercing above the deep external sphincter and the internal opening approaching the dentate line.Conventional surgical procedures for high complex anal fistulas remove most of the external sphincter and damage the anorectal ring.Postoperative loss of anal function can cause physical and mental damage.Transanal opening of the intersphincteric space(TROPIS)is an effective procedure that completely preserves the external anal sphincter.However,its clinical application is limited by challenges in the localization of the internal opening of a fistula and the high risk of complications.On the basis of our clinical experience,we modified the TROPIS procedure for the treatment of treating high complex anal fistulas.CASE SUMMARY A patient with a high complex anal fistula located above the anorectal ring underwent modified TROPIS,which involved sepsis drainage and identification of the internal opening in the intersphincteric space.The patient with the high complex anal fistula recovered well postoperatively,without any postoperative complications or anal dysfunction.Anal function returned to normal after 17 months of follow-up.CONCLUSION The modified TROPIS procedure is the most minimally invasive surgery for anal fistulas that minimally impairs anal function.It allows the complete removal of infected anal glands and reduces the risk of postoperative complications.Modified TROPIS via the intersphincteric approach is an alternative sphincter-preserving treatment for high complex anal fistulas.

Bioengineering Downstream Technology Online Open Course Drives SPOC Hybrid Teaching Reform Based on Ideological and Political Education

In the context of emerging engineering disciplines,a hybrid teaching reform for the Bioengineering Downstream Technology course,based on ideological and political education and online open courses,is being carried out.This reform focuses on aspects such as“building a professional teacher team for ideological and political education,scientifically designing the ideological and political teaching system,innovating classroom teaching methods,and improving both formative and summative evaluation systems.”The“Craftsmanship in Education and Cultivating Soul and Roots”small private online course hybrid teaching reform for the Bioengineering Downstream Technology online open course provides a replicable model for the comprehensive implementation of ideological and political education in engineering courses and offers a reference for advancing ideological and political education and hybrid teaching reform in new engineering disciplines.

基于CAPE-OPEN标准的简捷炼油过程建模及常减压蒸馏流程在线模拟

简捷炼油过程模型广泛应用于运行监测、在线计算、实时优化等领域,但大多数模型只是将输入、输出变量进行关联,无法计算出各组分流量组成,难以集成在模拟软件中进行全流程模拟。本研究简化了炼油分离过程,开发了基于CAPE-OPEN标准的简捷炼油塔模型。首先,将炼油过程简化为连续的分离单元,根据实际产品数据校正模型参数,实现某一实际工况流程模拟;其次,将模型参数与实际工况操作变量数据相结合,采用径向基函数插值确定操作变量对模型参数的影响关系,实现多种工况流程模拟;最后,通过常减压蒸馏工业装置实例的3种工况进行验证。结果表明:各工况模拟结果与Aspen计算结果相比,初馏塔塔顶油馏出温度点偏差大多在2%以内,常减压蒸馏塔各侧线油的馏出温度点平均偏差在3%以内;与实际结果相比,平均误差都在5%以内,符合工程允许误差范围要求。所建模型的计算速度快,各塔均在0.2 s左右完成计算,适用于在线生产、调度等。

我国高质量教育资源供给机制创新与路径研究——来自美国“#GoOpen”计划的启示

数字化是当下教育改革的重点,也是未来教育发展的趋势。无论是作为“十四五”规划中的战略举措,还是党的二十大中提出的必然要求,构建数字化教育资源为主体的高质量教育资源体系在当下具有必要性与迫切性。美国#GoOpen计划自实施以来,在教育资源数字化、个性化、均等化三个方面均取得了一定成果。通过对该计划官方文件与政策进行解读,对其内涵与特点进行分析,我国在进行高质量教育资源建设及其供给路径探究过程中应当重视统筹规划,循序渐进,同时完善多重考核与评估机制,结合社会多方力量,保证每个学习者的享有权利,最终走向教育公平,共同发展。

MdDGK3-like as a negative regulator participates in ALA-induced PP2AC to promote stomatal opening in apple leaves

5-Aminolevulinic acid(ALA)can inhibit abscisic acid(ABA)-induced stomatal closure.However,the molecular mechanism is unclear.In this study,we found that ALA upregulated the MdPP2AC expression and PP2A activity in the apple(Malus domestica Borkh.cv.‘Fuji’)leaves.With the promoter of MdPP2AC as bait,a diacylglycerol kinase MdDGK3-like was selected by the Yeast One Hybrid(Y1H)from the cDNA library of the epidermis of apple leaves treated by exogenous ALA.Additional to binding the promoter of MdPP2AC,MdDGK3-like was found to inhibit the transcription activity of MdPP2AC promoter,while ALA significantly eliminated the role of MdDGK3-like.In tobacco leaves,MdDGK3-like was localized in the nucleus of stomatal guard cells.Therefore,MdDGK3-like might act as a transcription factor negatively regulating MdPP2AC expression and causing stomatal closure.To further identify MdDGK3-like functions,several transiently transgenic apple leaves(including overexpression and interference)were established.The results revealed that overexpression of MdDGK3-like promoted stomatal closure by increasing Ca^(2+)and H_(2)O_(2)and decreasing flavonol levels in the guard cells.Conversely,MdDGK3-like(i)led the stomatal opening with lower levels of Ca^(2+)and H_(2)O_(2)but higher flavonols.Based on these,we proposed a new hypothesis that ALA up-regulated MdPP2AC expression via negatively regulating the expression of MdDGK3-like to up-regulate PP2A expression and the enzyme activity,which improved the stomatal aperture.Since it was the first time that MdDGK3-like was showed to act as a transcription factor,the proposed model provided a new insight onto the mechanisms of ALA-induced stomatal opening.

CsIPT1b and CsUGT85A2 delay female corolla opening in cucumber by regulating the content of cytokinins

Corolla opening is essential for the propagation of unisexual flowering plants,meanwhile commodity fruits with opening corolla have higher commodity value in cucumber fresh food market.Until now,there is little research on the mechanism of corolla opening in cucumber.In a previous paper,we identified a unique cucumber(Cucumis sativus)line(‘6457’)that possesses super ovaries and shows delayed corolla opening when nutrient supplies are abundant.We also previously showed that the expression of CsIPT1b(isopentenyl transferase)and CsUGT85A2(cytokinin glycosyltransferase)is correlated with the delayed opening of the female corolla.Here,we investigated the mechanism of delayed female corolla opening in cucumber by conducting transgenic experiments,hormone assays,and yeast one-hybrid assays.CsIPT1b and CsUGT85A2 positively and negatively regulated delayed female corolla opening,respectively.In CsIPT1b-overexpressing plants and CsUGT85A2 knockout plants,the content of the trans-zeatin riboside,trans-zeatin,and N6-isopentenyladenosine was increased.Overall,our findings indicate that CsIPT1b and CsUGT85A2 were important regulators of the timing of female corolla opening.These genes could thus be targets to cucumber molecular breeding of fruit with flowers remaining on the tip.

Has China-ASEAN Trade opening increased China’ s carbon emissions?

This study uses carbon emission data at the provincial level in China between 1998-2018 and the proportion of the total import and export trade between provinces and the Association of Southeast Asian Nations(ASEAN)in GDP to measure the level of China-ASEAN trade openness.It examines the impact of China ASEAN trade openness on carbon emissions and its transmission mechanism,and selects the RMB/USD exchange rate as an instrumental variable to address the endogeneity of China-ASEAN trade openness variables.The impact of China-ASEAN trade openness on China’s environment is estimated within a two-stage least squares framework.The results show that trade openness between China and ASEAN positively impacts China’s environment and can facilitate carbon emission reduction.The scale,structural,and technology effects brought by China-ASEAN trade liberalization jointly promote China’s carbon dioxide emission reduction.An inverted“U”relationship is found between economic growth and environmental quality in China,and some provinces and municipalities have now crossed the inflection point of the curve,in which carbon emi ssions decrease with an increase in per capita wealth.

基于YOLO-OpenMax的水声通信信号开集识别方法

水声通信信号调制方式随着技术进步从典型的传统调制方式发展为水声通信机厂商私有开发的新型调制方式,这使得现有的水声通信信号闭集调制识别技术实用性受到制约,但现阶段鲜有研究基于深度学习的水声通信信号调制方式的开集识别方法。针对此现状,提出一种基于YOLO图像检测识别网络和OpenMax模型的开集识别方法。利用YOLOv5网络的输出特点,将传统OpenMax模型的处理方法进行改进,提出一种两步测试方法,实现了在多径信道下的水声通信信号的开集识别。仿真实验表明:在归一化系数为0.5,信噪比等于10 dB条件下的归一化开集识别准确率达到90%以上,实测数据同样验证了本文方法的有效性。

Effect of fence opening configurations on dune development

Fences have been widely used in coastal protection engineering for their low cost,simple deployment,and easy integration with ecosystems.The effects of fence porosity and height on dune development have been investigated while not much attention has been paid to the effects of fence opening configurations,such as opening size and geometry,and porosity distributions.In this study,we deployed eight fences with same height and similar porosity,but different opening configurations on a sandy beach in Pingtan,Fujian Province.Results indicate that there is a similar two-dune-one-trough pattern for all fences at the beginning of dune development,and opening size,orientation,and geometry,and porosity distribution control the leeward dune peak locations.Fences with small openings and non-uniform porosity have high trapping efficiency,and upper denser porosity may be the optimal design as these fences have the highest trapping efficiency and capacity.The conclusions from this study can provide guidance on practical fence design.

Postdoctoral Openings in Wenzhou University(China)for Chemistry,Chemical Engineering and Materials Science

About us:The Clige of Cemistry and Materials Engineering(CME)in Wenzhou University(Zhejing Province,China)is looking for postdoctoral candidates(up to 25) specialized in Chemistry Chemical Engineering and Materials Secence. The college has is Chemistry program ranking ESI Top 6‰ worldwide.

Analysis of the Changes in Rural Chinese Family Structure since Reform and Opening Up

This article uses data from censuses since 1982 to reveal changes in the family structure of rural China since the launch of reform and opening up and against the backdrop of institutional relocation,social transformation and an aging population.Since the advent of reform and opening up,rural family structure and its changes can be divided into two phases.Before the 1990 s,the household contract responsibility system was implemented,labor in rural villages was still mainly engaged in farming,and the number of nuclear families remained stable with a steady rise.After the 1990 s,as reform progress deepened,substantial numbers of young and middle-aged laborers in rural villages began to relocate into non-farming sectors and aging in rural villages rose.As those born in the early days of the family planning policy gradually matured,family structure was directly affected and changed in new ways and forms not seen before.Vocational divisions of labor among the parents of young families and married offspring emerged and the significance of cooperation for family economy and daily life between parents and offspring rose in importance.Also,the prevalence of immediate families with three generations climbed while the standard nuclear families declined,the ratio of middle-aged couples with young children that worked outside the home increased,the function of middle-aged and senior parents in the upbringing of infants and children enhanced,and the commonness of incomplete family types such as only grandparents with grandchildren increased.During this phase,the number of seniors living alone surged to the point of becoming a matter worthy of attention.

Forty Years of Reform and Opening Up and the Building of a Moderately Prosperous Society

Over the past forty years of reform and opening up,the Communist Party of China(CPC)has led people of all ethnic groups in the country to carry out the practice of building a moderately prosperous society.Combining Marxism with the contemporary reality of China,the CPC has adapted Marxism to the Chinese context and enriched the theory of building a moderately prosperous society since its initiation.In practice,China already achieved the goal of ensuring the people a moderately prosperous life and is now striving to secure a decisive victory in building a moderately prosperous society in all respects,making tremendous progress in economic and social development.To complete the building of a moderately prosperous society in all respects and achieve the intended goal,China should accelerate the advancement of the targeted poverty alleviation strategy,continue to improve the people’s livelihood,and maintain sustained and sound economic and social development.

Discussion and Practice of Online and Offline Mixed Teaching Reform of Advertising Art Design Major in Open Education

Teaching reform is an important work indispensable for the long-term development of the open university,and it is also the development trend of the advertising art design major in open education to keep up with the new media era.Based on the current situation of advertising art design major in open education,this paper analyzes the necessity of implementing the online and offline mixed teaching reform in this major,and puts forward the specific teaching reform measures in three aspects.

A Model of China’s Opening-up and Development

Over the past decade,China’s free trade zones have progressively formed a high-level innovation pattern of reform and opening-up in areas that extend from coastal regions to border provinces.They have become a leading force of high-level opening-up,a pioneer of in-depth reform,and a major platform that serves the national strategy.As pilot platforms for comprehensive reform and opening-up,they are now taking on a more arduous mission.

OPENING TO THE CHALLENGE --An economy thrives in openness and withers in seclusion

pening-up has always been a hot topic at the China International Import Expo(CIIE),the world's first import expo held at the national level.During the sixth CIIE,the Hongqiao International Economic Forum held on November 6 attracted many participants from government departments,academia,and the business sector to conduct in-depth discussions on global trade and the challenges it faces.Participants agreed that multi-party dialogue is key to the issue.

RIDING ON OPENING-UP

Forty-five years on,China’s opening-up drive has raked in an accumulated foreign investment of US$2.9 trillion with more than 1 million foreign-funded firms established in the country.A raft of policies and measures have been rolled out for greater integration in globalization.China’s first pilot free trade zone(FTZ)in Shanghai’s Pudong New Area,established to undertake transformative reforms on a trial basis that could later be applied across the country,is also celebrating its 10th year.From that single pioneer,China today has 22 FTZs,and the Hainan Free Trade Port,which are all testbeds for advancing reform and opening-up.