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Management of Spontaneous Intracerebral Haemorrhage (sICH) at the University Hospital of Brazzaville (CONGO)
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作者 Ekouele Mbaki Hugues Brieux Ngoma Niangui Léocia Exaucée +5 位作者 Diatewa Josué Euberma Boukaka Kala Rel Gerald Ngackosso Olivier Brice Mpandzou Ghislain Armel Boukassa Léon Ossou-Nguiet Paul Macaire 《Neuroscience & Medicine》 2024年第1期23-38,共16页
Spontaneous intracerebral haemorrhage (sICH) is characterised by bleeding within the brain parenchyma, without any accompanying vascular malformation, parenchymal abnormality or coagulation disorder. The study aimed t... Spontaneous intracerebral haemorrhage (sICH) is characterised by bleeding within the brain parenchyma, without any accompanying vascular malformation, parenchymal abnormality or coagulation disorder. The study aimed to depict the management of sICH at the University Hospital of Brazzaville (UHB). It was an observational, descriptive, and cross-sectional analysis. Data collection was conducted retrospectively, covering the period from January 1, 2020 to August 31, 2022, spanning two years and eight months. The study examined socio-demographic, diagnostic, therapeutic, and evolutionary variables. We included 274 cases. We observed 160 men (58.4%) and 114 women (41.6%), resulting in a sex ratio of 1.4. The mean age was 55.3 ± 11.4 years, with ages ranging from 31 to 93 years. The detection of sICH was typically a result of experiencing motor deficits (59.5%) or disorders of consciousness (37.2%). The weightiness of one half of the body was the most common reason for seeking medical advice. Hematoma was capsulo-lenticular in 159 cases (58%) and capsulo-thalamic in 63 cases (23%). Hematomas were <30 ml in 162 cases (59.1%) and >30 ml in 112 cases (40.9%), and associated with hydrocephalus in 11.7% of cases. Conservative medical treatment was administered in 257 cases (94.2%) while surgical treatment was performed in 16 cases (5.8%). The surgical techniques used were external ventricular drainage (EVD) in 2 cases, ventriculo-peritoneal shunt in 5 cases, and hematoma evacuation in 10 cases. Death occurred before the 7th day of hospitalisation in 73 cases (57.8%) and after in 46 cases (42.2%). The median time to death was four days (Q1 = 2 days;Q3 = 7 days), with extremes of 0 and 216 days. . 展开更多
关键词 Spontaneous Intracerebral haemorrhage management BRAZZAVILLE
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Frontal Sinus Fractures: Management at the Yalgado Ouedraogo University Hospital Centre (Burkina Faso)
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作者 Arsène Coulibaly Patrik Gane-Bang +2 位作者 Joseph Wend-Toin Biogo Ibraïma Traoré Tarcissus Konsem 《Open Journal of Stomatology》 2024年第1期42-54,共13页
Introduction: Frontal sinus fractures are potentially serious. They are defined as a solution of continuity, open or closed, of one or both bone tables of the frontal sinus. This study aims to report on the management... Introduction: Frontal sinus fractures are potentially serious. They are defined as a solution of continuity, open or closed, of one or both bone tables of the frontal sinus. This study aims to report on the management of them at the Yalgado OUEDRAOGO University Hospital Centre. Methodology: It is a descriptive cross-sectional study with retrospective collection from January 01, 2016 to December 31, 2018. Patients with frontal sinus fractures were managed at the Yalgado OUEDRAOGO University Hospital Centre through CT-scan proof. Results: Over three years, a total of 102 cases of frontal sinus fractures were collected with 29.9 years as average age. There were 96 men. Workers in the informal sector and pupils/students represented 58.90% of patients. The residence of the patients was urban in 68.80% of cases and rural in 31.40%. Road traffic accidents (RTAs) happened in 90.20%, and involved 2-wheelers in 98.20%. None of these drivers was wearing a helmet. The type III frontal fracture of Ioannides et al. represented 51.9% of cases. In 89.21% of cases, other facial and/or cranioencephalic injuries were compounded to frontal sinus fractures. No surgical management was observed in 82 (80.39%) patients and surgical management in 20 (19.61%) patients. The outcome was favourable, but sequelae and/or complications were noted in 10 patients who had surgery and 30 patients who did not. Conclusion: These results enforce helmet wearing for all riders of two-wheeled machines. In addition, vaccinations to prevent meningitis in frontal sinus fractures with dural breach should be systematic. 展开更多
关键词 management Frontal Sinus Fracture Burkina Faso
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The Impact of Human Resource Management on University Development
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作者 Zhangwu Tian Roberto M.Arguelles 《Proceedings of Business and Economic Studies》 2024年第1期231-236,共6页
As competition in the education industry intensifies and the knowledge economy evolves,the significance of Human Resource Management(HRM)in university institutions.This study aims to explore how HRM affects the sustai... As competition in the education industry intensifies and the knowledge economy evolves,the significance of Human Resource Management(HRM)in university institutions.This study aims to explore how HRM affects the sustainable development and competitiveness improvement of universities.This article begins with a theoretical analysis to define the concept of HRM and its particular relevance within university education.The subsequent analysis examines the multi-dimensional framework of university development,encompassing its connotation,goals,and key influencing factors.The article further elaborates on the positive effects of HRM on university teaching quality,scientific research capabilities,organizational culture,and social services.On this basis,the main challenges currently faced by university HRM are discussed,such as talent mobility,institutional constraints,resource limitations,and internationalization pressure.Finally,optimization strategies are proposed,including building a scientific human resources system,enhancing talent training and development,fostering diversity among teaching staff,and improving decision-making efficiency and transparency.The conclusions of this study aim to provide strategic insights for university education managers to better utilize human resource advantages and promote the comprehensive and sustainable development of universities. 展开更多
关键词 Human resources management university education COMPETITIVENESS TALENT DEVELOPMENT
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Management and Construction of University Books and Materials Under the Background of the Internet
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作者 Min Zhang 《Journal of Contemporary Educational Research》 2024年第5期110-116,共7页
The rapid development and popularization of Internet technology has provided important support for the informatization reform of various industries.University books and materials have the characteristics of large quan... The rapid development and popularization of Internet technology has provided important support for the informatization reform of various industries.University books and materials have the characteristics of large quantities and difficult storage and management.Its digital storage and management platform construction can effectively realize the digital storage and real-time retrieval of books and materials,and help students and teachers to find and use books and materials more quickly.Especially in recent years,with the update of intelligent platforms and other technologies,the resource-sharing platform of university books and materials can realize more convenient book information retrieval without the limitation of time and space.This paper mainly explores the optimization path and platform construction scheme of university libraries and information management under the background of the Internet,hoping to provide some theoretical references for university library managers. 展开更多
关键词 Internet Colleges and universities Books and materials management CONSTRUCTION
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Enhancing Hazardous Chemical Management in Chinese University Laboratories:Strategies for Safety and Efficiency
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作者 Yizhe Li 《Journal of Electronic Research and Application》 2024年第1期1-6,共6页
This paper examines the management of hazardous chemicals in Chinese university laboratories,identifying key challenges and proposing improvements.It reviews current practices and safety measures,highlighting deficien... This paper examines the management of hazardous chemicals in Chinese university laboratories,identifying key challenges and proposing improvements.It reviews current practices and safety measures,highlighting deficiencies such as inadequate safety systems and insufficient awareness among personnel.The study emphasizes the necessity of tailored safety management systems,the integration of digital tracking technologies like Radio Frequency Identification,and enhanced safety training for staff.The proposed recommendations aim to mitigate risks and enhance laboratory safety and efficiency.In conclusion,the paper asserts that a comprehensive approach,encompassing improved management systems,technological advancements,and educational initiatives,is essential for safer chemical handling in academic research environments. 展开更多
关键词 Hazardous chemicals Laboratory safety RFID technology Safety management Chinese universities
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Optimization Analysis of Human Resource Management Strategies of Nantong University,a Local Comprehensive University in China
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作者 Fei Jin 《Proceedings of Business and Economic Studies》 2024年第2期1-7,共7页
This study analyzes the current situation and challenges of Nantong University amid the rapid development of higher education,addressing aspects such as faculty structure,administrative management efficiency,and promo... This study analyzes the current situation and challenges of Nantong University amid the rapid development of higher education,addressing aspects such as faculty structure,administrative management efficiency,and promotion mechanisms.Through questionnaire surveys and field research,coupled with SWOT analysis and various theoretical methods,a comprehensive analysis was conducted on Nantong University’s internal and external environment.The study proposes an improved comprehensive development strategy and implementation measures,which include updating management concepts,strengthening professional training,optimizing employment conditions,and improving salary systems.Ultimately,this study provides practical strategies for human resource management and the transformational development of Nantong University and other local comprehensive universities. 展开更多
关键词 Local comprehensive universities Transformation and development Human resource management SWOT
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Ruptured Ectopic Pregnancy: Epidemiology and Management in the General Surgery Department of the Ignace Deen National Hospital, Conakry University Hospital
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作者 Barry Mamadou Sakoba Barry Boubacar +2 位作者 Guirassy Mariam Touré Aboubacar Diallo Aissatou Taran 《Open Journal of Obstetrics and Gynecology》 2024年第4期503-508,共6页
Introduction: The aim of this study was to contribute to improving the quality of GEUR management in the general surgery department and in the maternity ward of the Ignace Deen national hospital, Conakry University Ho... Introduction: The aim of this study was to contribute to improving the quality of GEUR management in the general surgery department and in the maternity ward of the Ignace Deen national hospital, Conakry University Hospital. Methodology: This was a retrospective, descriptive study lasting two years (January 1, 2020 to December 31, 2022), carried out in the general surgery and gyneco-obstetrics departments of the Ignace Deen national hospital, Conakry University Hospital. We included all patients with a ruptured ectopic pregnancy who received surgical treatment during the study period. Results: We collected 13,524 cases of surgical interventions in the two services, among them, we recorded 89 cases or 0.66% GEUR. The average age of the patients was 24.26 years. Brides were the most represented with 80.96% of cases. Women practicing a liberal profession were 51.69% (n = 46) and housewives 26.97% (n = 24). Clinically, amenorrhea was noted in all patients, i.e. 100%, abdominal-pelvic pain in 95.2% (n = 85) of cases, metrorrhagia in 94.08% (n = 84), abdominal-pelvic sensitivity in 97.44% (n = 87) of cases and anemia in 85.39% of cases. The GEUR was ampullary in 69.66% (n = 62) cases. Salpingectomy was performed in 90.72% (n = 81). The surgical outcomes were satisfactory in 98.87% (n = 88) of cases. We recorded one case of surgical site infection. We have not recorded any deaths. The average length of hospitalization was 4 days. Conclusion: GEUR is relatively high in our context. A good understanding of the prognostic factors of GEUR, awareness and family planning could reduce GEUR. 展开更多
关键词 Ruptured Ectopic Pregnancy Epidemiology and management
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Blockchain and Digital Transformation of University Asset Management
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作者 Junjian Tang Xiaoqiang Li Wenqi Qu 《Open Journal of Applied Sciences》 2024年第1期85-100,共16页
As educational activities realize value transmission and value realization through a digital form, the Digital transformation of universities continues to advance. The quantity of asset data continues to grow, with in... As educational activities realize value transmission and value realization through a digital form, the Digital transformation of universities continues to advance. The quantity of asset data continues to grow, with internal value reflected in education, management, and services, while external value is reflected in policies, resources and reputation. Therefore, effective management of university assets is particularly important. Blockchain is an important infrastructure for Digital transformation, which provides a trusted environment for the occurrence of various collaborations and will reshape many collaboration mechanisms. This paper discusses the current situation and problems faced by universities in the process of Digital transformation. We analyze the development opportunities brought about by Digital transformation and the specific problems faced by physical asset management in detail. We discuss the data platform optimization, asset data application, digital asset security, planning strategy, and construction path of digital transformation involved in the physical asset management of universities. 展开更多
关键词 Blockchain Asset management Digitizatio
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The Inner Logic and Practical Path of University student Education Management from the Perspective of“One-Stop”Student Community Construction in Universities
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作者 Yutong Zhou 《Journal of Educational Theory and Management》 2024年第2期32-36,共5页
The“one-stop”student community is an important component of the education system in the new era of universities,and is an important practical base for university students to carry out practical education and moral e... The“one-stop”student community is an important component of the education system in the new era of universities,and is an important practical base for university students to carry out practical education and moral education.However,the construction of student communities still faces practical problems such as insufficient strength and lack of effective support in the current education system.Therefore,building a reasonable“one-stop”student community operation mode and exploring effective practical methods are the key to promoting student growth and development,stimulating learning willingness,and enhancing service awareness.They are also a powerful development and key force for highquality construction of student communities and the effectiveness of university education. 展开更多
关键词 “One-stop” Education management Community construction
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Collaborative Cultivation of Ideological and Political Education and Undergraduate Management in Colleges and Universities Under the Guidance of Moral Education
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作者 Jianyuan Xie 《Journal of Contemporary Educational Research》 2024年第4期221-225,共5页
Guided by moral education,improving the ideological and moral quality of college students is an important goal of college education.To achieve this goal,it is necessary to strengthen ideological and political educatio... Guided by moral education,improving the ideological and moral quality of college students is an important goal of college education.To achieve this goal,it is necessary to strengthen ideological and political education and continuously improve the level of undergraduate management.This paper outlines the feasibility of collaborative cultivation of ideological and political education and undergraduate management in colleges and universities and analyzes its significance and the specific implementation strategies,with a view to providing valuable references for relevant colleges and universities to carry out educational work. 展开更多
关键词 Moral education Colleges and universities Ideological and political education Undergraduate management
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Assessing Strategies of Obstetric Fistula Management by Nurses/Midwives of Yaoundé Central Hospital and University Teaching Hospital
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作者 Dobgima Walter Pisoh Takang William Ako +5 位作者 Bassong Yves Pierre Tah Nji Joy Mah Achuo Ascensius Mforteh Tameh Theodore Boten Bouyom Pierre Merlin Helen Kuokuo Kimbi 《Open Journal of Obstetrics and Gynecology》 2023年第7期1210-1233,共24页
Every minute, a woman dies in pregnancy, and for every woman who dies 20 - 30 others will survive with morbidity, one of which is obstetrical fistula. Women who suffer from obstetric fistula experience continuous inco... Every minute, a woman dies in pregnancy, and for every woman who dies 20 - 30 others will survive with morbidity, one of which is obstetrical fistula. Women who suffer from obstetric fistula experience continuous incontinence of urine and/or stool, stigma, social isolation and associated health problems. The World Health Organization estimates that there are currently more than 2 million women living with untreated obstetric fistula mostly in sub-Saharan Africa and South-East Asia, as well as in various other parts of the world. Caring for fistula patients and nursing them back to full physical and mental health can be one of the most challenging and also rewarding tasks undertaken by nurses. The surgery cannot succeed without proper pre-, peri- and post-operative care. The patients undoubtedly recover better with high-quality care—meaning the truly holistic, generous, and selfless care of a nurse who has the skills, understanding and determination to help these very vulnerable patients. Objective: This research seeks to assess the strategies of obstetric fistula management by nurses/midwives of Yaoundé central hospital and CHU by exploring the care they offer to clients pre-operatively, post-operatively, and when they are discharged from the hospital. Achieving Millennium Development Goal (MDG) 3 still remains a challenge to the developing countries although maternal mortality reduction is a priority agenda of each country. Methodology: This retrospective cross-sectional descriptive study design employed a sample of 100 nurses/midwives on active service, and who have at least managed a case of obstetric fistula. A quantitative questionnaire was used to collect data, which was analyzed using SPSS version 23. Results: The study proved a highly significant difference between management and qualification, with a p-value of 0.002. Also, it showed that there was a statistically significant difference between longevity of service and management with a p-value of 0.001. A majority of respondents were nurse assistants (52%), and up to 43% of respondents had 11 - 20 years of work experience. Up to 53% did not offer standard care with respect to their qualification, and up to 52% did not offer standard care with respect to their longevity in service. Conclusion: VVF is the most common type of obstetric fistula with a frequency of 6 to 10 cases, there is an overall poor management of obstetric fistula by nurses and midwives in YCH and CHU. There is an urgent need to train and retrain these health workers on the management strategies of obstetric fistula and to remind them of their personal commitment as care givers. 展开更多
关键词 Obstetric Fistula management MIDWIVES Nurses
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The Application Mode of Blockchain in University Asset Management
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作者 Junjian Tang Wenqi Qu 《Journal of Computer and Communications》 2023年第1期12-25,共14页
With the development of higher education, the scale of university assets has become more diversified, complex and decentralized. Traditional asset management is inefficient. Information is not transparent and manageme... With the development of higher education, the scale of university assets has become more diversified, complex and decentralized. Traditional asset management is inefficient. Information is not transparent and management responsibilities are unclear. This paper analyzes the difficulties in the process of asset management in universities and discusses the advantages of blockchain technology. We research on the application of blockchain technology in the process of asset management in universities and propose a framework design based on blockchain technology to standardize the asset management process. The result improves the efficiency of asset inventory and ensures the credibility of asset information. It helps to prevent asset information tampering, and improves the security of asset data. It also pushes the asset management mode from static to dynamic. 展开更多
关键词 Blockchain Asset management Higher Education
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Management of Immediate Postpartum Hemorrhage at the University Hospital Center of the Sino-Central African Friendship
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作者 Roch M’betid-Degana Gilles-Davy Kossa-Ko-Ouakoua +7 位作者 Geniva Gracelia Vanciane M’betid-Degana Gamaliel Kerebi Sandrine Sana-Ozako Durant Poutou-Piri Samuel Gondje Appolinaire Hepatraud Eugène Serdouma Antoine Doui-Doumgba 《Open Journal of Obstetrics and Gynecology》 2023年第11期1783-1790,共8页
Introduction: Immediate postpartum hemorrhages constitute a frequent maternal complication and remain at the forefront of maternal death in our countries. Objective: Contribute to improving the management of immediate... Introduction: Immediate postpartum hemorrhages constitute a frequent maternal complication and remain at the forefront of maternal death in our countries. Objective: Contribute to improving the management of immediate postpartum hemorrhage in our context with a view to reducing maternal mortality. Patients and Methods: We conducted a retrospective descriptive and analytical study over a period of 12 months from January 1<sup>st</sup> to December 31<sup>st</sup> 2020. Results: We collected a total of 109 files on a total of 4360 deliveries. The frequency of postpartum haemorrhages was of the order of 2.5%. The most represented age group was between 20 and 24 years old. Pauciparas represented the majority of our study population. 64.5% of patients were uneducated. These hemorrhages occurred in patients who often gave birth outside the department with 63.8%. The main causes of postpartum hemorrhage were cervical tears (51.2%) and partial placental retention (30.7%). The majority of these deliveries (48.8%) were carried out by midwives followed by assistant midwives (33.2%). Active management of the third period of delivery was systematic and immediate followed by the valve examination completed by the infusion of oxytocin in case of uterine atony, tranexamic acid ans misoprostol intrarectally. In the event of persistent hemorrhage, suture of the cervical lesions, ligation of the cervical vessels or even laparotomy either for the selective ligation of the blood vessels or for the hysterectomy for hemostasis were practiced. We do not have a Nalador, nor a Bakry balloon, nor an Interventional Radiology service for embolization of the uterine arteries. We deplore 1.3% of deaths from afibrinogenemia. Conclusion: The frequency of immediate postpartum hemorrhages is lower in our health facility. This is due to the rapid handling of cases. Improving the quality of services offered to women during childbirth can further help reduce the frequency of these hemorrhages. 展开更多
关键词 HAEMORRHAGE Postpartum Immediate university Hospital Center of the Sino-Central African Friendship
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Occupation-related airborne diseases: Management and prevention of tuberculosis among nurses working in Ekiti State University Teaching Hospital
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作者 Olaolorunpo OLORUNFEMI Damilola SAMUEL +2 位作者 Joseph Adekunle ADEBIYI Adewole Peter AKINDIPE Wakeel Adelani TIJANI 《Journal of Integrative Nursing》 2023年第4期280-285,共6页
Objective:More health workers die from infectious diseases such as tuberculosis(TB)than from any other infectious agent,so the current study is designed to assess TB treatment and preventive measures as they relate to... Objective:More health workers die from infectious diseases such as tuberculosis(TB)than from any other infectious agent,so the current study is designed to assess TB treatment and preventive measures as they relate to nursing care practice.Materials and Methods:A cross-sectional study was conducted among 82 nurses from December 2022 to January 2023.The data were collected through a self-developed questionnaire and analyzed by frequency table and analysis of variance(ANOVA)statistics.Results:The researchers found that nurses have sufficient knowledge on Infection Prevention and Control(IPC)policy,but not all nurses follow this management protocol,and the reason for their action is addressed in this study.The management and preventive measures used by the participants were identified as:proper cough etiquette/hygiene,working in a well-ventilated area,use of mask,appropriate disposal of used items and so on was reported.Moreover,this study also discovered that there is a positive correlation between nurses who had received training in IPC policy and their use of airborne preventive measures for TB patients(F=1.87,P=0.002)as well as a positive correlation between the availability of resources and their adherence to the proper use of airborne preventive measures when caring for TB patients(F=1.96,P˂0.001).Conclusion:We proposed infection and control training for nurses and adequate equipment supplies to the TB ward which are required in quick TB diagnosis,and must be carried out on a regular basis by health-care personnel,for efficient nursing practice.Ensuring proper safety equipment and isolation units should be available and assessable for nurses or other health workers showing sign or symptoms of TB.Similarly,it is necessary for government to put in place the control and regulations that will safeguard nurses and mandate them to adopt TB prevention protocols,which will aid in lowering the prevalence of TB among nurses. 展开更多
关键词 AIRBORNE management of TB TUBERCULOSIS TB preventive measures TUBERCULOSIS
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Problems and Countermeasures in the Informatization of Archives Management in University Library
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作者 Song Shan Weiguo Xie 《Journal of Electronic Research and Application》 2023年第2期1-6,共6页
To improve the level of informatization of university library archives management,the problems existing in the information construction of university library archives management are analyzed and some practical solutio... To improve the level of informatization of university library archives management,the problems existing in the information construction of university library archives management are analyzed and some practical solutions are proposed in this paper.These solutions can effectively reduce the investment in human resources and equipment and facilities and improve the utilization rate of resources for computer application of university library archives management. 展开更多
关键词 LIBRARY Archives management INFORMATIZATION
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Patient satisfaction and follow-up adherence to glaucoma case management clinic in China 被引量:1
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作者 Hao Lin Hu-Jie Lu +3 位作者 Wen-Zhe Zhou Shu-Shu Zuo Yan-Yan Chen Shao-Dan Zhang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第1期73-81,共9页
AIM:To assess glaucoma patient satisfaction and follow-up adherence in case management and identify associated predictors to improve healthcare quality and patient outcomes.METHODS:In this cross-sectional study,a tota... AIM:To assess glaucoma patient satisfaction and follow-up adherence in case management and identify associated predictors to improve healthcare quality and patient outcomes.METHODS:In this cross-sectional study,a total of 119 patients completed a Patient Satisfaction Questionnaire-18 and a sociodemographic questionnaire.Clinical data was obtained from the case management system.Follow-up adherence was defined as completing each follow-up within±30d of the scheduled time set by ophthalmologists during the study period.RESULTS:Average satisfaction scored 78.65±7,with an average of 4.39±0.58 across the seven dimensions.Age negatively correlated with satisfaction(P=0.008),whilst patients with follow-up duration of 2 or more years reported higher satisfaction(P=0.045).Multivariate logistics regression analysis revealed that longer follow-up durations were associated with lower follow-up adherence(OR=0.97,95%CI,0.95-1.00,P=0.044).Additionally,patients with suspected glaucoma(OR=2.72,95%CI,1.03-7.20,P=0.044)and those with an annual income over 100000 Chinese yuan demonstrated higher adherence(OR=5.57,95%CI,1.00-30.89,P=0.049).CONCLUSION:The case management model proves effective for glaucoma patients,with positive adherence rates.The implementation of this model can be optimized in the future based on the identified factors and extended to glaucoma patients in more hospitals. 展开更多
关键词 GLAUCOMA patient satisfaction follow-up adherence case management
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Overview of the immunological mechanisms in hepatitis B virus reactivation:Implications for disease progression and management strategies 被引量:1
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作者 Hui Ma Qing-Zhu Yan +2 位作者 Jing-Ru Ma Dong-Fu Li Jun-Ling Yang 《World Journal of Gastroenterology》 SCIE CAS 2024年第10期1295-1312,共18页
Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and manageme... Hepatitis B virus(HBV)reactivation is a clinically significant challenge in disease management.This review explores the immunological mechanisms underlying HBV reactivation,emphasizing disease progression and management.It delves into host immune responses and reactivation’s delicate balance,spanning innate and adaptive immunity.Viral factors’disruption of this balance,as are interac-tions between viral antigens,immune cells,cytokine networks,and immune checkpoint pathways,are examined.Notably,the roles of T cells,natural killer cells,and antigen-presenting cells are discussed,highlighting their influence on disease progression.HBV reactivation’s impact on disease severity,hepatic flares,liver fibrosis progression,and hepatocellular carcinoma is detailed.Management strategies,including anti-viral and immunomodulatory approaches,are critically analyzed.The role of prophylactic anti-viral therapy during immunosuppressive treatments is explored alongside novel immunotherapeutic interventions to restore immune control and prevent reactivation.In conclusion,this compre-hensive review furnishes a holistic view of the immunological mechanisms that propel HBV reactivation.With a dedicated focus on understanding its implic-ations for disease progression and the prospects of efficient management stra-tegies,this article contributes significantly to the knowledge base.The more profound insights into the intricate interactions between viral elements and the immune system will inform evidence-based approaches,ultimately enhancing disease management and elevating patient outcomes.The dynamic landscape of management strategies is critically scrutinized,spanning anti-viral and immunomodulatory approaches.The role of prophylactic anti-viral therapy in preventing reactivation during immunosuppressive treatments and the potential of innovative immunotherapeutic interventions to restore immune control and proactively deter reactivation. 展开更多
关键词 Hepatitis B virus reactivation Immunological mechanisms Disease progression management strategies Immune response
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Heat transfer enhanced inorganic phase change material compositing carbon nanotubes for battery thermal management and thermal runaway propagation mitigation 被引量:1
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作者 Xinyi Dai Ping Ping +4 位作者 Depeng Kong Xinzeng Gao Yue Zhang Gongquan Wang Rongqi Peng 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第2期226-238,I0006,共14页
Developing technologies that can be applied simultaneously in battery thermal management(BTM)and thermal runaway(TR)mitigation is significant to improving the safety of lithium-ion battery systems.Inorganic phase chan... Developing technologies that can be applied simultaneously in battery thermal management(BTM)and thermal runaway(TR)mitigation is significant to improving the safety of lithium-ion battery systems.Inorganic phase change material(PCM)with nonflammability has the potential to achieve this dual function.This study proposed an encapsulated inorganic phase change material(EPCM)with a heat transfer enhancement for battery systems,where Na_(2)HPO_(4)·12H_(2)O was used as the core PCM encapsulated by silica and the additive of carbon nanotube(CNT)was applied to enhance the thermal conductivity.The microstructure and thermal properties of the EPCM/CNT were analyzed by a series of characterization tests.Two different incorporating methods of CNT were compared and the proper CNT adding amount was also studied.After preparation,the battery thermal management performance and TR propagation mitigation effects of EPCM/CNT were further investigated on the battery modules.The experimental results of thermal management tests showed that EPCM/CNT not only slowed down the temperature rising of the module but also improved the temperature uniformity during normal operation.The peak battery temperature decreased from 76℃to 61.2℃at 2 C discharge rate and the temperature difference was controlled below 3℃.Moreover,the results of TR propagation tests demonstrated that nonflammable EPCM/CNT with good heat absorption could work as a TR barrier,which exhibited effective mitigation on TR and TR propagation.The trigger time of three cells was successfully delayed by 129,474 and 551 s,respectively and the propagation intervals were greatly extended as well. 展开更多
关键词 Inorganic phase change material Carbon nanotube Battery thermal management Thermal runaway propagation Fire resistance ENCAPSULATION
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Whole-process case management effects on mental state and selfcare ability in patients with liver cancer 被引量:1
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作者 Man-Di Ju Qin Qin Meng Li 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第3期833-841,共9页
BACKGROUND Regarding the incidence of malignant tumors in China,the incidence of liver cancer ranks fourth,second only to lung,gastric,and esophageal cancers.The case fatality rate ranks third after lung and cervical ... BACKGROUND Regarding the incidence of malignant tumors in China,the incidence of liver cancer ranks fourth,second only to lung,gastric,and esophageal cancers.The case fatality rate ranks third after lung and cervical cancer.In a previous study,the whole-process management model was applied to patients with breast cancer,which effectively reduced their negative emotions and improved treatment adherence and nursing satisfaction.METHODS In this single-center,randomized,controlled study,60 randomly selected patients with liver cancer who had been admitted to our hospital from January 2021 to January 2022 were randomly divided into an observation group(n=30),who received whole-process case management on the basis of routine nursing mea-sures,and a control group(n=30),who were given routine nursing measures.We compared differences between the two groups in terms of anxiety,depression,the level of hope,self-care ability,symptom distress,sleep quality,and quality of life.RESULTS Post-intervention,Hamilton anxiety scale,Hamilton depression scale,memory symptom assessment scale,and Pittsburgh sleep quality index scores in both groups were lower than those pre-intervention,and the observation group had lower scores than the control group(P<0.05).Herth hope index,self-care ability assessment scale-revision in Chinese,and quality of life measurement scale for patients with liver cancer scores in both groups were higher than those pre-intervention,with higher scores in the observation group compared with the control group(P<0.05).CONCLUSION Whole-process case management can effectively reduce anxiety and depression in patients with liver cancer,alleviate symptoms and problems,and improve the level of hope,self-care ability,sleep quality,and quality of life,as well as provide feasible nursing alternatives for patients with liver cancer. 展开更多
关键词 Liver cancer Mental state Self-care ability Whole-process case management Life quality NURSING
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Investigation of the Acceptability of Cultured Meat in University Students
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作者 Merve Kumru Hulya Demir 《Food and Nutrition Sciences》 CAS 2024年第2期151-169,共19页
Background: Over the past 20 years, cultured meat has drawn a lot of public attention as a potential solution to issues with animal husbandry, including inadequate use of natural sources, improper animal welfare pract... Background: Over the past 20 years, cultured meat has drawn a lot of public attention as a potential solution to issues with animal husbandry, including inadequate use of natural sources, improper animal welfare practices, and possible risks to public health and safety. The novel method of producing meat through culture reduces the need for animals to produce muscle fiber, thereby obviating the necessity for animal slaughter. Apart from its ethical advantages, cultured meat presents a possible way to fulfill the expanding need for food among growing populations. The purpose of this research was to find out whether Turkish students would be willing to pay for and accept cultured meat. Technique: Method: 371 university students who willingly consented to fill out a questionnaire and provide demographic data make up the research sample. Questions from previous studies on the acceptability of cultured meat were compiled to create the survey. The research’s data collection took place in March and April of 2022. The research was completed in June 2022 after the data had been processed and analyzed. Results: The results showed that the majority of participants were female and had omnivorous eating habits. Based on the results of the Bonferroni correction test, students with a higher intention to purchase and consume cultured meat were those who received economics and business education. Students with two years of university education had a higher overall survey score than those with four years of education (p < 0.05). Furthermore, it is discovered that there is a negative correlation between the participants’ ages and their Factor 2 (using cultured meat as an alternative to industrial meat) and Factor 3 (consuming and purchasing it) section points (r = -109, p = 0.036) (r = -0.121, p = 0.019). In conclusion, university students generally have a negative outlook on health-related issues, such as eating cultured meat as an alternative. 展开更多
关键词 Cultured Meat university Students
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