Listening Comprehension test of CET-6 has a great adjustment in its item types and weighting of score since December,2015, however, there have been few researches concerning the validity of newly innovated CET-6 liste...Listening Comprehension test of CET-6 has a great adjustment in its item types and weighting of score since December,2015, however, there have been few researches concerning the validity of newly innovated CET-6 listening comprehension test.This paper tries to explore the construct validity and content validity of it. Based on the comparison between the test contents of lis-tening and the test requirements in CET syllabus,it is found that CET-6 listening shows good content relevance. Structural equa-tion modeling(SEM) was used to investigate the construct validity of CET-6 listening, which demonstrates that it mainly tests stu-dents' ability to understand details and inference, while ignoring socio-linguistic competence and psych-physiological compe-tence. Therefore, certain changes are desirable to increase the validity of the listening part of CET-6.展开更多
The title compound 2-[(4-methoxy-6-methylthio-2-pyrimidinyl)aminocarbonyl- aminosulfonyl]benzoic acid methyl ester (C15H16N4O6S2, Mr = 412.44) was obtained by the reaction of (4-methoxy-6-methylthio-2-pyrimidinyl)amin...The title compound 2-[(4-methoxy-6-methylthio-2-pyrimidinyl)aminocarbonyl- aminosulfonyl]benzoic acid methyl ester (C15H16N4O6S2, Mr = 412.44) was obtained by the reaction of (4-methoxy-6-methylthio-2-pyrimidinyl)amine with 2-methoxylcarbonylbenzene-sulfonylisocya- nate. The crystal is of monoclinic, space group P21/c with a =11.169(3), b = 9.508(3), c = 17.690(5) ? b = 91.593(5), Z = 4, V = 1877.9(10) 3, Dc = 1.459 g/cm3, F(000) = 856, m(MoKa) = 0.324 mm-1, R = 0.0690 and wR = 0.1368 for 3301 observed reflections (I > 2s(I)). The N(1)H…N(3) and N(2)H…O(4) hydrogen bonds can be observed. In the molecule the phenyl plane(I), pyrimi- din-2-yl-urea bridge plane(Ⅱ) and ester plane(Ⅲ) form three conjugated systems.展开更多
Reductive debromination of anhydro-6-(R)-hydroxycthyl-6-(R) 7 by zinc in ammonium acetate gave 9 in 81% yield with high stcreosclectivity of 6-(α):6-(β)= 13: 1
Objective\ To investigate the perioperative chaneges of plasma levels of necrosis factor α(TNF α) and interleukin 6 (IL 6). Methods\ Thirty patients undergoing upper abdominal operations were randomly divied int...Objective\ To investigate the perioperative chaneges of plasma levels of necrosis factor α(TNF α) and interleukin 6 (IL 6). Methods\ Thirty patients undergoing upper abdominal operations were randomly divied into epidural blockade (EB) group and intravenous procaine balanced anesthesia (IPBA) group. The plasma levels of TNF α and IL 6 were monitored perioperatively. Results\ There were no significant changes in TNF α in both groups during or after operation. But plasma IL 6 levels on the first postoperative day were significantly higher than that before induction of anesthesia in both groups [EB:(0 39±0 07) vs (0 28±0 07) ng/ml, P<0.05; IPBA:(0 42±0 07) vs (0.27±0.08) ng/ml, P<0.05]. Conclusion\ The results suggest that IL 6 is a cytokine more active than TNF α after upper abdominal operation. Surgical stress might be a more important stimulator for IL 6 release.展开更多
Geometry optimization of p-C_(6)H_(4)-connected cyclo[20]carbon(p-C_(6)H_(4)-C_(20))was carried out at M062X/6-311G(d,p)level,three kinds of bond orders(Mayer,Laplacian,and Wiberg),electron-hole distributions,localize...Geometry optimization of p-C_(6)H_(4)-connected cyclo[20]carbon(p-C_(6)H_(4)-C_(20))was carried out at M062X/6-311G(d,p)level,three kinds of bond orders(Mayer,Laplacian,and Wiberg),electron-hole distributions,localized orbital locators(LOL),and infrared(IR)spectrum were also performed at the same level.Based on TD-DFT M062X/6-311G(d,p)method,the first 20 excited states and ultraviolet(UV)spectra of p-C_(6)H_(4)-C_(20) were calculated.Calculation results of π-electron delocalization analyses prove thatπ-electron delocalization of p-C_(6)H_(4)-C_(20) is more likely to occur on shorter C-C bonds rather than longer C-C bonds,and inside/outside of the ring plane rather than above/below the ring plane.Two absorption peaks of p-C_(6)H_(4)-C_(20) locate at about 319 nm and 236 nm,respectively.展开更多
文摘Listening Comprehension test of CET-6 has a great adjustment in its item types and weighting of score since December,2015, however, there have been few researches concerning the validity of newly innovated CET-6 listening comprehension test.This paper tries to explore the construct validity and content validity of it. Based on the comparison between the test contents of lis-tening and the test requirements in CET syllabus,it is found that CET-6 listening shows good content relevance. Structural equa-tion modeling(SEM) was used to investigate the construct validity of CET-6 listening, which demonstrates that it mainly tests stu-dents' ability to understand details and inference, while ignoring socio-linguistic competence and psych-physiological compe-tence. Therefore, certain changes are desirable to increase the validity of the listening part of CET-6.
基金The project was supported by the National Natural Science Foundation of China (20372021) and Natural Science Foundation of Hunan Province (03JJY3018)
文摘The title compound 2-[(4-methoxy-6-methylthio-2-pyrimidinyl)aminocarbonyl- aminosulfonyl]benzoic acid methyl ester (C15H16N4O6S2, Mr = 412.44) was obtained by the reaction of (4-methoxy-6-methylthio-2-pyrimidinyl)amine with 2-methoxylcarbonylbenzene-sulfonylisocya- nate. The crystal is of monoclinic, space group P21/c with a =11.169(3), b = 9.508(3), c = 17.690(5) ? b = 91.593(5), Z = 4, V = 1877.9(10) 3, Dc = 1.459 g/cm3, F(000) = 856, m(MoKa) = 0.324 mm-1, R = 0.0690 and wR = 0.1368 for 3301 observed reflections (I > 2s(I)). The N(1)H…N(3) and N(2)H…O(4) hydrogen bonds can be observed. In the molecule the phenyl plane(I), pyrimi- din-2-yl-urea bridge plane(Ⅱ) and ester plane(Ⅲ) form three conjugated systems.
文摘Reductive debromination of anhydro-6-(R)-hydroxycthyl-6-(R) 7 by zinc in ammonium acetate gave 9 in 81% yield with high stcreosclectivity of 6-(α):6-(β)= 13: 1
基金The study was supported by the National Natural Science Foundation of China.No 38970700.
文摘Objective\ To investigate the perioperative chaneges of plasma levels of necrosis factor α(TNF α) and interleukin 6 (IL 6). Methods\ Thirty patients undergoing upper abdominal operations were randomly divied into epidural blockade (EB) group and intravenous procaine balanced anesthesia (IPBA) group. The plasma levels of TNF α and IL 6 were monitored perioperatively. Results\ There were no significant changes in TNF α in both groups during or after operation. But plasma IL 6 levels on the first postoperative day were significantly higher than that before induction of anesthesia in both groups [EB:(0 39±0 07) vs (0 28±0 07) ng/ml, P<0.05; IPBA:(0 42±0 07) vs (0.27±0.08) ng/ml, P<0.05]. Conclusion\ The results suggest that IL 6 is a cytokine more active than TNF α after upper abdominal operation. Surgical stress might be a more important stimulator for IL 6 release.
文摘Geometry optimization of p-C_(6)H_(4)-connected cyclo[20]carbon(p-C_(6)H_(4)-C_(20))was carried out at M062X/6-311G(d,p)level,three kinds of bond orders(Mayer,Laplacian,and Wiberg),electron-hole distributions,localized orbital locators(LOL),and infrared(IR)spectrum were also performed at the same level.Based on TD-DFT M062X/6-311G(d,p)method,the first 20 excited states and ultraviolet(UV)spectra of p-C_(6)H_(4)-C_(20) were calculated.Calculation results of π-electron delocalization analyses prove thatπ-electron delocalization of p-C_(6)H_(4)-C_(20) is more likely to occur on shorter C-C bonds rather than longer C-C bonds,and inside/outside of the ring plane rather than above/below the ring plane.Two absorption peaks of p-C_(6)H_(4)-C_(20) locate at about 319 nm and 236 nm,respectively.
