The quantized chemical reaction resonantly driven by multiple MIR-photons:From nature to the artificial

Biochemical reactions in vivo occur at the temperature usually lower than that in vitro,however the underlying mechanism still remains a challenge.Inspired by our recent studies of adenosine triphosphate(ATP)releasing photons to resonantly drive DNA replication in a quantum way,we propose a quantized chemical reaction driven by multiple mid-infrared(MIR)photons.The space confinement effect of enzymes on a reactant molecule increases the lifetime of excitation state of its bond vibration,providing a chance for the bond to resonantly absorb multiple photons.Although the energy of each MIR photon is significantly lower than that of chemical bond,the resonant absorption of multiple photons can break the appointed bond of confined molecules.Different from the traditional thermochemistry and photochemistry,the quantized chemical reactions could have a high energy efficiency and ultrahigh selectivity.In addition,we also suggest a quantum driving source for our quantum-confined superfluid reactions proposed previously.The quantized chemical reaction resonantly driven by multiple MIR photons holds great promise to develop novel approaches for the chemical engineering in future.

3-photon fluorescence and third-harmonic generation imaging of myelin sheaths in mouse digital skin in vivo:A comparative study

Myelin sheaths wrapping axons are key structures that help maintain the propagation speed of action potentials in both central and peripheral nervous systems(CNS and PNS).However,noninvasive,deep imaging technologies visualizing myelin sheaths in the digital skin in vivo are lacking in animal models.3-photon°uorescence(3PF)imaging excited at the 1700-nm window enables deep imaging of myelin sheaths,but necessitates labeling by exogenous°uorescent dyes.Since myelin sheaths are lipid-rich structures which generate strong third-harmonic signals,in this paper,we perform a detailed comparative experimental study of both third-harmonic generation(THG)and 3PF imaging in the mouse digital skin in vivo.Our results show that THG imaging also enables visualization of myelin sheaths deep in the mouse digital skin,which shows colocalization with 3PF signals from labeled myelin sheaths.Besides its superior label-free advantage,THG does not su®er from photobleaching due to its 3PF property.

Comparison of the emission wavelengths by a single fluorescent dye on in vivo 3-photon imaging of mouse brains

Multiphoton microscopy(MPM)is a powerful imaging technology for brain research.The imaging depth in MPM is partly determined by emission wavelength of fluorescent labels.It has been demonstrated that a longer emission wavelength is favorable for signal detection as imaging depth increases.However,there has been no comparison with near-infrared(NIR)emission.In order to quantitatively analyze the effect of emission wavelength on 3-photon imaging of mouse brains in vivo,we utilize the same excitation wavelength to excite a single fluorescent dye and simultaneously collect NIR and orange-red emission fluorescence at 828 nm and 620 nm,respectively.Both experimental and simulation results show that as the imaging depth increases,NIR emission decays less than orange-red fluorescent emission.These results show that it is preferable to shift the emission wavelength to NIR to enable more e±cient signal collection deep in the brain.

Monte Carlo Simulation on Glueball Search at BESIII

The J/ψ radiative decays are suggested as promising modes for glueball search. A full Monte Carlo simulation of J/ψ →γηη and γηη, based on the design of BESIII detector, is performed to study the sensitivity of searching for a possible tensor glueball at BESIII.

EXPERIMENTAL STUDY OF 3-PHOTON ANNIHILATION OF POSITRONS AND ELECTRONS

The results of a series of experiments on 3-photon annihilation of positrons and electrons, including the energy-angular correlation, angular distribution, energy spectrum and linear polarization of the annihilation photons, the method of measuring the intensities of 3-photon annihilation, and the upper limit of axion production in the triplet positronium decay, are reported.

Zero-Absorption Isolines in a 2-Photon 2-Level Atom Model

The c-number atomic Bloch equations modelling the coupling of a 2-photon 2-1evel single atom with a non-resonant （A # O） squeezed vacuum （SV） radiation reservoir show that： （i） The quantum interference （QI） process, of parameter f O, between the 2-photon transition channels causes coupling of the atomic variables （inversion and polarisation）, and, （ii） The SV reservoir parameters （N, M） induce periodic coefficients and hence inhibited oscillatory behaviour in the atomic variables. Perturbative analytical solutions of these non-autonomous B1och equations are derived and used to calculate the absorption spectrum of a weak field probing the system. Of particular, the zero-absorption isolines in the relevant （N, f）- and （A, f ）-planes of the the largest set of points, where absorption is zero, in parameter （M） of the SV reservoir. system parameters are identified computationally. It is found that, the （A, f）-plane depends on the choice of the degree of squeezing

Excited states of coherent state and their nonclassical properties

QUANTIZED radiation fields exhibiting nonclassical properties have been of great theoretical andexperimental interest in the last two decades. It is shown that various nonclassical states suchas squeezed state and Schrodinger cat state can be generated out of coherent state in thenonlinear process of the interaction of atom and field although the radiation field in a

High-aspect-ratio nanoimprint process chains

Different methods capable of developing complex structures and building elements with high-aspect-ratio nanostructures combined with microstructures,which are of interest in nanophotonics,are presented.As originals for subsequent replication steps,two families of masters were developed:(i)3.2μm deep,180 nm wide trenches were fabricated by silicon cryo-etching and(ii)9.8μm high,350 nm wide ridges were fabricated using 2-photon polymerization direct laser writing.Both emerging technologies enable the vertical smooth sidewalls needed for a successful imprint into thin layers of polymers with aspect ratios exceeding 15.Nanoridges with high aspect ratios of up to 28 and no residual layer were produced in Ormocers using the micromoulding into capillaries(MIMIC)process with subsequent ultraviolet-curing.This work presents and balances the different fabrication routes and the subsequent generation of working tools from masters with inverted tones and the combination of hard and soft materials.This provides these techniques with a proof of concept for their compatibility with high volume manufacturing of complex micro-and nanostructures.