Objective To investigate the effective mechanism of the treatments with electroacupuncture (EA) at "BǎiHuì" (GV20) and "ShuǐGōu" acupoints for cerebral infarction. Methods Forty rats were randomly divi...Objective To investigate the effective mechanism of the treatments with electroacupuncture (EA) at "BǎiHuì" (GV20) and "ShuǐGōu" acupoints for cerebral infarction. Methods Forty rats were randomly divided into four groups as normal group (n = 10), sham-operation group (n = 10), model group (n = 10), EA group (n = 10). The acute cerebral infarction model in rats was developed by blocking the middle cerebral artery with an intraluminal thread. The contents of t-PA,PAI-1 ,D-D and Fib were estimated in each group. Results The contents of t-PA, PAI-1, D-D and Fib increased significantly (P〈0.01) in the model group as compared to the normal and sham-operation group. The contents of t-PA, PAI-1, D-D and Fib decreased significantly (P〈0.05-0.01) in the EA group as compared to the normal group. Conclusion The balance function of blood clotting and fibrinolysis were good and the cerebral abnormal blood was improved in EA group.展开更多
基金the research project item of the Department of Educationin Hubei province(No . D200516006)
文摘Objective To investigate the effective mechanism of the treatments with electroacupuncture (EA) at "BǎiHuì" (GV20) and "ShuǐGōu" acupoints for cerebral infarction. Methods Forty rats were randomly divided into four groups as normal group (n = 10), sham-operation group (n = 10), model group (n = 10), EA group (n = 10). The acute cerebral infarction model in rats was developed by blocking the middle cerebral artery with an intraluminal thread. The contents of t-PA,PAI-1 ,D-D and Fib were estimated in each group. Results The contents of t-PA, PAI-1, D-D and Fib increased significantly (P〈0.01) in the model group as compared to the normal and sham-operation group. The contents of t-PA, PAI-1, D-D and Fib decreased significantly (P〈0.05-0.01) in the EA group as compared to the normal group. Conclusion The balance function of blood clotting and fibrinolysis were good and the cerebral abnormal blood was improved in EA group.