Indanone-containing compounds are very important components of various natural products,chemical drugs,agrochemicals and functionalized material fields.1,3-Indanedione is a typical cyclic 1,3-dicarbonyl compound with ...Indanone-containing compounds are very important components of various natural products,chemical drugs,agrochemicals and functionalized material fields.1,3-Indanedione is a typical cyclic 1,3-dicarbonyl compound with three contiguous reactive electrophilic and nucleophilic sites.The easily prepared 2-arylidene-1,3-indanediones are activeα,β-unsaturated carbonyl compounds and could act as 1,3-dipolarophile,1,4-dienophile and 1-oxa-1,3-diene,etc.On the other hand,the homodimer(bindone)and cyclotrimer(truxenone)derived from basecatalyzed self-condensation of 1,3-indanedione are also reactive carbonyl compounds.Therefore,1,3-indanedione and its derivatives can be employed as key substrates in various domino and multicomponent reactions.In this review,we summarized the recent progress on the domino and multicomponent reactions of 1,3-indanedione,especially on our achievements on the synthetic applications for the complex indanone-containing carbocyclic and heterocyclic compounds.展开更多
基金supported by the National Natural Science Foundation of China(No.21871227).
文摘Indanone-containing compounds are very important components of various natural products,chemical drugs,agrochemicals and functionalized material fields.1,3-Indanedione is a typical cyclic 1,3-dicarbonyl compound with three contiguous reactive electrophilic and nucleophilic sites.The easily prepared 2-arylidene-1,3-indanediones are activeα,β-unsaturated carbonyl compounds and could act as 1,3-dipolarophile,1,4-dienophile and 1-oxa-1,3-diene,etc.On the other hand,the homodimer(bindone)and cyclotrimer(truxenone)derived from basecatalyzed self-condensation of 1,3-indanedione are also reactive carbonyl compounds.Therefore,1,3-indanedione and its derivatives can be employed as key substrates in various domino and multicomponent reactions.In this review,we summarized the recent progress on the domino and multicomponent reactions of 1,3-indanedione,especially on our achievements on the synthetic applications for the complex indanone-containing carbocyclic and heterocyclic compounds.
