Objective: To identify and isolate the chemical compounds of Phaleria macrocarpa(P.macrocarpa) fruit ethanolic extract.Methods: Dried fruit of P.macrocarpa was extracted with 90% ethanol and partitioned between n-hexa...Objective: To identify and isolate the chemical compounds of Phaleria macrocarpa(P.macrocarpa) fruit ethanolic extract.Methods: Dried fruit of P.macrocarpa was extracted with 90% ethanol and partitioned between n-hexane/H_2O and ethyl acetate/H_2O.The organic layer was fractionated by various stationary phase and identified by using combined data of 1D [(proton nuclear magnetic resonance(NMR), carbon-13 NMR)], 2D-NMR(heteronuclear multiplequantum correlation and heteronuclear multiple-bond correlation), and mass spectrum.Results: Purification of n-hexane and ethyl acetate fractions from ethanolic extract of P.macrocarpa fruit resulted in isolation of nine compounds.Conclusions: A new compound was isolated and identified as glyceryl pentacosanoate.Also, two xanthones, which are 1,7-dihydroxy-3,6-dimethoxyxanthone and 1,6,7-trihydroxy-3-methoxyxanthone, are firstly reported to be isolated from P.macrocarpa.展开更多
Objective To study the chemical constituents from the root barks of Cudrania cochinchinensis. Methods The chemical constituents were isolated and purified by silica gel column chromatography. The structures of the com...Objective To study the chemical constituents from the root barks of Cudrania cochinchinensis. Methods The chemical constituents were isolated and purified by silica gel column chromatography. The structures of the compounds were identified on the basis of spectral data(MS,1H-NMR,13C-NMR, and 2D NMR) and by the comparison of spectroscopic data with the reported values in the literatures. Results A new xanthone, 1,6,7-trihydroxy-4-(1,1-dimethylallyl)-3-methoxyxanthone(1) and a known prenylated xanthone 1,5,6-trihydroxy-4-(1,1-dimethylallyl)-3-methoxyxanthone(isocudraniaxanthone B, 2) were isolated from the root barks of C. cochinchinensis. Conclusion Compound 1 is a new prenylated xanthone. Isomers 1 and 2 are obtained from this plant for the first time.展开更多
基金Supported by PT Dexa Medica with grant number 120/IMC/DLBS/2014
文摘Objective: To identify and isolate the chemical compounds of Phaleria macrocarpa(P.macrocarpa) fruit ethanolic extract.Methods: Dried fruit of P.macrocarpa was extracted with 90% ethanol and partitioned between n-hexane/H_2O and ethyl acetate/H_2O.The organic layer was fractionated by various stationary phase and identified by using combined data of 1D [(proton nuclear magnetic resonance(NMR), carbon-13 NMR)], 2D-NMR(heteronuclear multiplequantum correlation and heteronuclear multiple-bond correlation), and mass spectrum.Results: Purification of n-hexane and ethyl acetate fractions from ethanolic extract of P.macrocarpa fruit resulted in isolation of nine compounds.Conclusions: A new compound was isolated and identified as glyceryl pentacosanoate.Also, two xanthones, which are 1,7-dihydroxy-3,6-dimethoxyxanthone and 1,6,7-trihydroxy-3-methoxyxanthone, are firstly reported to be isolated from P.macrocarpa.
基金National Natural Science Foundation of China(81060261)Guangxi Natural Science Foundation(2012GXNSFAA053021)Guangxi Teachers Education University Science Research Funds(2011-4)
文摘Objective To study the chemical constituents from the root barks of Cudrania cochinchinensis. Methods The chemical constituents were isolated and purified by silica gel column chromatography. The structures of the compounds were identified on the basis of spectral data(MS,1H-NMR,13C-NMR, and 2D NMR) and by the comparison of spectroscopic data with the reported values in the literatures. Results A new xanthone, 1,6,7-trihydroxy-4-(1,1-dimethylallyl)-3-methoxyxanthone(1) and a known prenylated xanthone 1,5,6-trihydroxy-4-(1,1-dimethylallyl)-3-methoxyxanthone(isocudraniaxanthone B, 2) were isolated from the root barks of C. cochinchinensis. Conclusion Compound 1 is a new prenylated xanthone. Isomers 1 and 2 are obtained from this plant for the first time.
