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Pulmonary Edema and Pleural Effusion Detection Using Efficient Net-V1-B4 Architecture and AdamW Optimizer from Chest X-Rays Images
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作者 Anas AbuKaraki Tawfi Alrawashdeh +4 位作者 Sumaya Abusaleh Malek Zakarya Alksasbeh Bilal Alqudah Khalid Alemerien Hamzah Alshamaseen 《Computers, Materials & Continua》 SCIE EI 2024年第7期1055-1073,共19页
This paper presents a novelmulticlass systemdesigned to detect pleural effusion and pulmonary edema on chest Xray images,addressing the critical need for early detection in healthcare.A new comprehensive dataset was f... This paper presents a novelmulticlass systemdesigned to detect pleural effusion and pulmonary edema on chest Xray images,addressing the critical need for early detection in healthcare.A new comprehensive dataset was formed by combining 28,309 samples from the ChestX-ray14,PadChest,and CheXpert databases,with 10,287,6022,and 12,000 samples representing Pleural Effusion,Pulmonary Edema,and Normal cases,respectively.Consequently,the preprocessing step involves applying the Contrast Limited Adaptive Histogram Equalization(CLAHE)method to boost the local contrast of the X-ray samples,then resizing the images to 380×380 dimensions,followed by using the data augmentation technique.The classification task employs a deep learning model based on the EfficientNet-V1-B4 architecture and is trained using the AdamW optimizer.The proposed multiclass system achieved an accuracy(ACC)of 98.3%,recall of 98.3%,precision of 98.7%,and F1-score of 98.7%.Moreover,the robustness of the model was revealed by the Receiver Operating Characteristic(ROC)analysis,which demonstrated an Area Under the Curve(AUC)of 1.00 for edema and normal cases and 0.99 for effusion.The experimental results demonstrate the superiority of the proposedmulti-class system,which has the potential to assist clinicians in timely and accurate diagnosis,leading to improved patient outcomes.Notably,ablation-CAM visualization at the last convolutional layer portrayed further enhanced diagnostic capabilities with heat maps on X-ray images,which will aid clinicians in interpreting and localizing abnormalities more effectively. 展开更多
关键词 Image classification decision support system EfficientNet-V1-B4 AdamW optimizer pulmonary edema pleural effusion chest X-rays
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干酪乳杆菌LK-1的发酵特性及其在菠萝果汁中的应用 被引量:1
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作者 杨莲 彭芍丹 +5 位作者 马俊杰 章程辉 吴广 黄晓兵 李积华 廖良坤 《食品工业科技》 CAS 北大核心 2024年第1期199-207,共9页
为利用干酪乳杆菌制备发酵菠萝果汁饮品,本研究对干酪乳杆菌LK-1(Lactobacillus casei LK-1,L. casei LK-1)的生长曲线、产酸、耐酸和耐糖等特性进行研究分析,并以活菌数和总酸为指标,通过单因素实验及响应面法考察L. casei LK-1发酵菠... 为利用干酪乳杆菌制备发酵菠萝果汁饮品,本研究对干酪乳杆菌LK-1(Lactobacillus casei LK-1,L. casei LK-1)的生长曲线、产酸、耐酸和耐糖等特性进行研究分析,并以活菌数和总酸为指标,通过单因素实验及响应面法考察L. casei LK-1发酵菠萝果汁的最佳条件。结果表明,L. casei LK-1在pH5~7和0%~10%质量分数葡萄糖环境下,具备良好的生长繁殖能力;在酸性(pH3)和高糖(40%质量分数葡萄糖)环境中培养3 h,其存活率分别为76%和71%;在MRS培养基中培养48 h,产酸量为5.35 g/kg,产酸能力良好,适用于果汁的发酵。L. casei LK-1发酵菠萝果汁的最佳条件为:初始pH6.8,发酵温度37℃,接种量1%(v/v),发酵时间30 h,此条件下制备的发酵菠萝果汁饮品活菌数为8.99±0.04 lg CFU/mL,总酸含量为7.16±0.26 g/kg,且色泽鲜亮,酸甜适口,风味较好,为L. casei LK-1在发酵食品中的进一步应用提供了理论和技术依据。 展开更多
关键词 干酪乳杆菌LK-1 菠萝果汁 发酵 工艺优化
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Optimization of Fermentation Conditions for Xylanase Production by Aspergillus niger NS-1 被引量:4
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作者 Mengting LIU Juanjuan DU +2 位作者 Yan ZHOU Jiawei HUANG Xin WANG 《Agricultural Biotechnology》 CAS 2016年第1期54-56,共3页
In this study, a xylanase-produeing Aspergillus niger strain, NS-1, was screened and isolated from agricultural and forestry wastes. Based on single-fac- tor experiments, the effects of different carbon sources, compo... In this study, a xylanase-produeing Aspergillus niger strain, NS-1, was screened and isolated from agricultural and forestry wastes. Based on single-fac- tor experiments, the effects of different carbon sources, composite carbon sources, nitrogen sources, calcium carbonate concentrations, initial pH and surfactants on xylanase production by A. niger NS-1 were investigated. The results indicated that the most appropriate carbon source was corncobs ; the best composite carbon source was corncobs + xylan, which was conducive to xylanase secretion; the most suitable nitrogen source was ammonium sulfate. Xylanase activity reached the highest in the medium added with 1.5% calcium carbonate and SDS as a surfactant with an initial pH of 5.0. This study provided the basis for the production of high-activity xylanase. 展开更多
关键词 Aspergillus niger NS-1 XYLANASE optimization Fermentation conditions
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A NEURAL-BASED NONLINEAR L_1-NORM OPTIMIZATION ALGORITHM FOR DIAGNOSIS OF NETWORKS* 被引量:8
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作者 He Yigang (Department of Electrical Engineering, Hunan University, Changsha 410082)Luo Xianjue Qiu Guanyuan(School of Electrical Engineering, Xi’an Jiaotong University, Xi’an 710049) 《Journal of Electronics(China)》 1998年第4期365-371,共7页
Based on exact penalty function, a new neural network for solving the L1-norm optimization problem is proposed. In comparison with Kennedy and Chua’s network(1988), it has better properties.Based on Bandler’s fault ... Based on exact penalty function, a new neural network for solving the L1-norm optimization problem is proposed. In comparison with Kennedy and Chua’s network(1988), it has better properties.Based on Bandler’s fault location method(1982), a new nonlinearly constrained L1-norm problem is developed. It can be solved with less computing time through only one optimization processing. The proposed neural network can be used to solve the analog diagnosis L1 problem. The validity of the proposed neural networks and the fault location L1 method are illustrated by extensive computer simulations. 展开更多
关键词 FAULT DIAGNOSIS L1-norm NEURAL optimization
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Design and optimization of purification process of sinomenine hydrochloride
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作者 Dandan Ren Shanshan Xiang +2 位作者 Yuwen Yan Ruiying Kong Xingchu Gong 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第3期63-72,共10页
Sinomenine hydrochloride is generally produced from Caulis Sinomenii. At present, the purification process in industrial production suffers from large amount of solid waste, high solvent toxicity, and low sinomenine h... Sinomenine hydrochloride is generally produced from Caulis Sinomenii. At present, the purification process in industrial production suffers from large amount of solid waste, high solvent toxicity, and low sinomenine hydrochloride yield. In this study, a new purification process for sinomenine hydrochloride was proposed by using the extract obtained from acid extraction of Caulis Sinomenii as the starting material.The process included the following steps: alkalization, extraction, water washing, acid–water stripping,drying, and crystallization. 1-Heptanol was used as the extractant. The distribution coefficients of sinomenine and sinomenine hydrochloride in 1-heptanol–water system were 27.4 and 0.0167, respectively.The dissociation constants of sinomenine hydrochloride were 8.27 and 11.24, respectively. Process parameters of the new purification process were optimized with experimental design. The extractant1-heptanol and sinomenine hydrochloride in the crystallization mother solution can be recycled in the new process. The purity of the obtained sinomenine hydrochloride crystals exceeded 85%, and the yield was about 70%. Compared with current industrial processes, safer extractant, less solid waste, and higher sinomenine hydrochloride yield can be achieved using the new purification process of sinomenine hydrochloride provided in this study. 展开更多
关键词 Sinomenine hydrochloride Process optimization EXTRACTION CRYSTALLIZATION 1-Heptanol
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A Superlinerly Convergent ODE-type Trust Region Algorithm for LC^1 Optimization Problems 被引量:5
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作者 OUYi-gui HOUDing-pi 《Chinese Quarterly Journal of Mathematics》 CSCD 2003年第2期140-145,共6页
In this paper, a new trust region algorithm for unconstrained LC1 optimization problems is given. Compare with those existing trust regiion methods, this algorithm has a different feature: it obtains a stepsize at eac... In this paper, a new trust region algorithm for unconstrained LC1 optimization problems is given. Compare with those existing trust regiion methods, this algorithm has a different feature: it obtains a stepsize at each iteration not by soloving a quadratic subproblem with a trust region bound, but by solving a system of linear equations. Thus it reduces computational complexity and improves computation efficiency. It is proven that this algorithm is globally convergent and locally superlinear under some conditions. 展开更多
关键词 LC1 optimization ODE methods trust region algorithm superlinear convergence
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A GLOBALLY AND SUPERLINEARLY CONVERGENT TRUST REGION METHOD FOR LC^1 OPTIMIZATION PROBLEMS 被引量:1
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作者 Zhang Liping Lai Yanlian Institute of Applied Mathematics,Academia Sinica,Beijing 100080. 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2001年第1期72-80,共9页
A new trust region algorithm for solving convex LC 1 optimization problem is presented.It is proved that the algorithm is globally convergent and the rate of convergence is superlinear under some reasonable assum... A new trust region algorithm for solving convex LC 1 optimization problem is presented.It is proved that the algorithm is globally convergent and the rate of convergence is superlinear under some reasonable assumptions. 展开更多
关键词 LC 1 optimization problem global and superlinear convergence trust region method.
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A SUPERLINEARLY CONVERGENT TRUST REGION ALGORITHM FOR LC^1 CONSTRAINED OPTIMIZATION PROBLEMS 被引量:3
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作者 欧宜贵 侯定丕 《Acta Mathematica Scientia》 SCIE CSCD 2005年第1期67-80,共14页
In this paper, a new trust region algorithm for nonlinear equality constrained LC1 optimization problems is given. It obtains a search direction at each iteration not by solving a quadratic programming subprobiem with... In this paper, a new trust region algorithm for nonlinear equality constrained LC1 optimization problems is given. It obtains a search direction at each iteration not by solving a quadratic programming subprobiem with a trust region bound, but by solving a system of linear equations. Since the computational complexity of a QP-Problem is in general much larger than that of a system of linear equations, this method proposed in this paper may reduce the computational complexity and hence improve computational efficiency. Furthermore, it is proved under appropriate assumptions that this algorithm is globally and super-linearly convergent to a solution of the original problem. Some numerical examples are reported, showing the proposed algorithm can be beneficial from a computational point of view. 展开更多
关键词 LC1 optimization ODE methods trust region methods superlinear convergence
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Performance Optimization of Torque Converters Based on Modified 1D Flow Model 被引量:3
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作者 吴光强 王立军 《Journal of Donghua University(English Edition)》 EI CAS 2012年第5期380-384,共5页
A methodology for performance optimization of torque converters is put forward based on the one-dimensional (1D) flow model. It is found that the inaccuracy of 1D flow model for predicting hydraulic performance at the... A methodology for performance optimization of torque converters is put forward based on the one-dimensional (1D) flow model. It is found that the inaccuracy of 1D flow model for predicting hydraulic performance at the low speed ratio is mainly caused by the separation phenomenon at the stator cascade which is induced by large flow impinging at the pressure side of the stator blades. A semi-empirical separation model is presented and incorporated to the original 1D flow model. It is illustrated that the improved model is able to predict the circumferential velocity components accurately, which can be applied to performance optimization. Then, the Pareto front is obtained by using the genetic algorithm (GA) in order to inspect the coupled relationship among stalling impeller torque capacity, stalling torque ratio and efficiency. The efficiency is maximized on the premise that a target stalling impeller torque capacity and torque ratio are achieved. Finally, the optimized result is verified by the computational fluid dynamics(CFD) simulation, which indicates that the maximal efficiency is increased by 0.96%. 展开更多
关键词 multi-objective optimization torque converter separation flow Pareto front one-dimensional 1 D) flow model
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Multisoliton Solutions of the (2+1)-Dimensional KdV Equation 被引量:1
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作者 ZHANG Jie-Fang HUANG Wen-Hua 《Communications in Theoretical Physics》 SCIE CAS CSCD 2001年第11期523-524,共2页
Using the extension homogeneous balance method,we have obtained some new special types of soliton solutions of the (2+1)-dimensional KdV equation.Starting from the homogeneous balance method,one can obtain a nonlinear... Using the extension homogeneous balance method,we have obtained some new special types of soliton solutions of the (2+1)-dimensional KdV equation.Starting from the homogeneous balance method,one can obtain a nonlinear transformation to simple (2+1)-dimensional KdV equation into a linear partial differential equation and two bilinear partial differential equations.Usually,one can obtain only a kind of soliton-like solutions.In this letter,we find further some special types of the multisoliton solutions from the linear and bilinear partial differential equations. 展开更多
关键词 multisoliton (2+1)-dimensions KdV EQUATION
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A FILTER-TRUST-REGION METHOD FOR LC^1 UNCONSTRAINED OPTIMIZATION AND ITS GLOBAL CONVERGENCE 被引量:1
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作者 ZhenghaoYang Wenyu Sun Chuangyin Dang 《Analysis in Theory and Applications》 2008年第1期55-66,共12页
In this paper we present a filter-trust-region algorithm for solving LC1 unconstrained optimization problems which uses the second Dini upper directional derivative. We establish the global convergence of the algorith... In this paper we present a filter-trust-region algorithm for solving LC1 unconstrained optimization problems which uses the second Dini upper directional derivative. We establish the global convergence of the algorithm under reasonable assumptions. 展开更多
关键词 nonsmooth optimization filter method trust region algorithm global conver- gence LC1 optimization
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乙型肝炎相关性肝硬化患者血清circMTO1表达水平及其与肝纤维化程度、预后的相关性
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作者 兰莹 何玲 +2 位作者 车茜 梁成宵 康殿巨 《广西医学》 CAS 2024年第2期255-259,共5页
目的分析乙型肝炎相关性肝硬化患者血清环状RNA线粒体tRNA翻译优化因子1(circMTO1)表达水平及其与肝纤维化程度、预后的关系。方法纳入115例乙型肝炎相关性肝硬化患者(乙肝肝硬化组)及120例慢性乙型肝炎患者(慢乙肝组)作为研究对象。根... 目的分析乙型肝炎相关性肝硬化患者血清环状RNA线粒体tRNA翻译优化因子1(circMTO1)表达水平及其与肝纤维化程度、预后的关系。方法纳入115例乙型肝炎相关性肝硬化患者(乙肝肝硬化组)及120例慢性乙型肝炎患者(慢乙肝组)作为研究对象。根据治疗后短期预后情况,将乙肝肝硬化组患者分为预后良好组(n=84)与预后不良组(n=31)。比较乙肝肝硬化组与慢乙肝组之间、预后良好组与预后不良组之间的血清circMTO1表达水平。分析乙肝肝硬化组血清circMTO1表达水平与肝纤维化分级的相关性。采用受试者工作特征曲线分析血清circMTO1表达水平对乙肝肝硬化组患者不良预后的预测价值。结果乙肝肝硬化组患者的血清circMTO1表达水平低于慢乙肝组,预后不良组患者的circMTO1表达水平低于预后良好组(P<0.05)。乙肝肝硬化组患者血清circMTO1表达水平与肝纤维化分级呈负相关(P<0.05)。血清circMTO1表达水平预测乙肝肝硬化组患者预后不良的曲线下面积为0.747,敏感度为77.40%,特异度为77.40%,最佳截断值为0.332。结论与未发生肝硬化的慢性乙型肝炎患者相比,乙型肝炎相关性肝硬化患者的血清circMTO1表达水平降低,且其与肝纤维化程度相关。circMTO1或可作为评估乙型肝炎相关性肝硬化患者预后的分子标志物。 展开更多
关键词 肝硬化 乙型肝炎 环状RNA线粒体tRNA翻译优化因子1 肝纤维化 预后
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Weed Classification Using Particle Swarm Optimization and Deep Learning Models
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作者 M.Manikandakumar P.Karthikeyan 《Computer Systems Science & Engineering》 SCIE EI 2023年第1期913-927,共15页
Weed is a plant that grows along with nearly allfield crops,including rice,wheat,cotton,millets and sugar cane,affecting crop yield and quality.Classification and accurate identification of all types of weeds is a cha... Weed is a plant that grows along with nearly allfield crops,including rice,wheat,cotton,millets and sugar cane,affecting crop yield and quality.Classification and accurate identification of all types of weeds is a challenging task for farmers in earlier stage of crop growth because of similarity.To address this issue,an efficient weed classification model is proposed with the Deep Convolutional Neural Network(CNN)that implements automatic feature extraction and performs complex feature learning for image classification.Throughout this work,weed images were trained using the proposed CNN model with evolutionary computing approach to classify the weeds based on the two publicly available weed datasets.The Tamil Nadu Agricultural University(TNAU)dataset used as afirst dataset that consists of 40 classes of weed images and the other dataset is from Indian Council of Agriculture Research–Directorate of Weed Research(ICAR-DWR)which contains 50 classes of weed images.An effective Particle Swarm Optimization(PSO)technique is applied in the proposed CNN to automa-tically evolve and improve its classification accuracy.The proposed model was evaluated and compared with pre-trained transfer learning models such as GoogLeNet,AlexNet,Residual neural Network(ResNet)and Visual Geometry Group Network(VGGNet)for weed classification.This work shows that the performance of the PSO assisted proposed CNN model is significantly improved the success rate by 98.58%for TNAU and 97.79%for ICAR-DWR weed datasets. 展开更多
关键词 Deep learning convolutional neural network weed classification transfer learning particle swarm optimization evolutionary computing Algorithm 1:Metrics Evaluation
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基于BP神经网络模型优化Fe_(1-x)O基氨合成催化剂
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作者 张书铭 刘化章 《化工进展》 EI CAS CSCD 北大核心 2024年第3期1302-1308,共7页
运用BP神经网络建立了助催化剂含量与催化剂活性之间的预测模型,对Fe_(1-x)O基氨合成催化剂的助催化剂进行优化。首先将前期实验数据整理归纳为含有3、4、5、6和7个助催化剂等5类催化剂,以助催化剂含量(体积分数)为输入变量,以425℃反... 运用BP神经网络建立了助催化剂含量与催化剂活性之间的预测模型,对Fe_(1-x)O基氨合成催化剂的助催化剂进行优化。首先将前期实验数据整理归纳为含有3、4、5、6和7个助催化剂等5类催化剂,以助催化剂含量(体积分数)为输入变量,以425℃反应器出口氨浓度(活性)为输出变量,对助催化剂进行优化。结果表明,BP神经网络预测模型拟合值均方误差最高为0.2784,预测值均方误差最高为0.1592,构建的BP神经网络模型准确度较高。在该模型的基础上,运用多种群遗传算法进行极值寻优,求解最优的催化剂配方,并进行实验验证。结果表明,根据优化结果制备5个样品的实验测定值与预测值的相对误差最高为2.88%,优化结果较为准确;含有7个助催化剂的催化剂活性最高为18.83%,比原样本的统计平均活性值(17.52%)高1.31%,相对提高7.48%,助催化剂含量优化取得满意的结果。 展开更多
关键词 Fe_(1-x)O 催化剂 助催化剂 神经网络 遗传算法 优化
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增强型群论优化算法求解折扣{0-1}背包问题
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作者 张寒崧 贺毅朝 +2 位作者 王静红 孙菲 李明亮 《计算机科学与探索》 CSCD 北大核心 2024年第6期1526-1542,共17页
群论优化算法(GTOA)是基于群论方法提出的一个离散演化算法,非常适于求解以整型向量为可行解的组合优化问题。为了进一步提高GTOA求解折扣{0-1}背包问题(D{0-1}KP)的性能,首先指出了它的随机线性组合算子(RLCO)未能充分考虑当前个体位... 群论优化算法(GTOA)是基于群论方法提出的一个离散演化算法,非常适于求解以整型向量为可行解的组合优化问题。为了进一步提高GTOA求解折扣{0-1}背包问题(D{0-1}KP)的性能,首先指出了它的随机线性组合算子(RLCO)未能充分考虑当前个体位置信息的不足,基于个体基因保留策略对其进行改进。然后,在随机反向变异算子(IRMO)中引入增强0分量变异策略,用于处理因个体0分量无法及时变异而导致的解的质量下降、种群多样性降低等问题。在改进上述两个算子的基础上,提出了增强型GTOA(EGTOA),并基于它给出求解D{0-1}KP的新方法。随后,将改进策略应用于二进制GTOA(GTOA-2),提出了增强型GTOA-2(EGTOA-2)及其求解D{0-1}KP的新方法。为了验证EGTOA和EGTOA-2的性能提高程度与优异性,分别利用它们求解四类大规模D{0-1}KP实例,通过与GTOA、GTOA-2以及求解D{0-1}KP的已有8个最先进算法的比较表明:EGTOA和EGTOA-2求得最优解的能力比GTOA和GTOA-2提高了至少1.14倍,比8个最先进算法提高了5%~60%,它们的平均性能比GTOA、GTOA-2以及8个最先进算法的性能更佳。因此,EGTOA和EGTOA-2是当前求解D{0-1}KP的最佳算法。 展开更多
关键词 群论优化算法 组合优化问题 折扣{0-1}背包问题 随机变异
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考虑源荷不确定性和N-1安全约束的电力系统优化调度
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作者 余雁琳 杨苹 +1 位作者 曾凯林 陈芯羽 《可再生能源》 CAS CSCD 北大核心 2024年第5期664-674,共11页
大规模风电并网增加了系统运行的不确定因素,文章利用快速可调资源平抑风电和负荷波动引发的功率不平衡,并考虑备用调用过程减少对系统潮流的影响。首先分析了风电和负荷预测误差的概率分布模型;然后,建立含N-1网络安全机会约束和旋转... 大规模风电并网增加了系统运行的不确定因素,文章利用快速可调资源平抑风电和负荷波动引发的功率不平衡,并考虑备用调用过程减少对系统潮流的影响。首先分析了风电和负荷预测误差的概率分布模型;然后,建立含N-1网络安全机会约束和旋转备用机会约束的电力系统优化调度模型,以系统调度总成本最小为目标优化机组出力;最后,基于起作用整数变量的识别方法的Benders分解法处理N-1网络安全约束,提高求解效率。利用修正的IEEE30节点系统,验证了所提模型能够保障系统备用可用性、经济性和安全性,充分挖掘抽水蓄能的快速可调能力。 展开更多
关键词 风电并网 N-1安全 旋转备用 优化调度
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固定化脂肪酶ANL-MARE催化酸解合成1-油酸-2-棕榈酸-3-亚油酸甘油三酯
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作者 康梦 何家强 +7 位作者 冯孔龙 黄早成 李一峰 苗建银 符姜燕 朱泽榕 刘果 曹庸 《现代食品科技》 CAS 北大核心 2024年第2期109-119,共11页
1-油酸-2-棕榈酸-3-亚油酸甘油三酯(OPL)是人乳中主要的脂质组成,为满足婴幼儿配方食品母乳化需求,该试验探究了新型固定化脂肪酶ANL-MARE催化制备OPL的方法。试验成功制备和表征了固定化酶ANLMARE,并以ANL-MARE为生物催化剂,建立了一... 1-油酸-2-棕榈酸-3-亚油酸甘油三酯(OPL)是人乳中主要的脂质组成,为满足婴幼儿配方食品母乳化需求,该试验探究了新型固定化脂肪酶ANL-MARE催化制备OPL的方法。试验成功制备和表征了固定化酶ANLMARE,并以ANL-MARE为生物催化剂,建立了一种用三棕榈酸甘油三酯(PPP)、油酸(OA)和亚油酸(LA)高效酶催化制备富含OPL结构脂的方法。经单因素和响应面试验优化,获得OPL最优合成工艺为:PPP与总脂肪酸的摩尔比1:14.27,OA与LA摩尔比为1:0.76,脂肪酶添加量12.70%,反应温度50℃,反应4 h,此条件下产物中OPL相对含量为47.93%,2位棕榈酸(sn-2 PA)占总棕榈酸(PA)的质量分数(sn-2 PA相对含量)为71.69%。此外,固定化酶ANL-MARE与商业脂肪酶相比,表现出较好的催化合成OPL的活性。综上所述,固定化酶ANL-MARE具有催化制备OPL结构脂的重大潜力,为人乳脂替代脂的高效制备提供了新策略和理论基础。 展开更多
关键词 1-油酸-2-棕榈酸-3-亚油酸甘油三酯 酶促酸解法 固定化脂肪酶 ANL-MARE 工艺优化
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LOCALIZED COHERENT STRUCTURES OF THE (2+1)-DIMENSIONAL HIGHER ORDER BROER-KAUP EQUATIONS
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作者 ZHANG Jie-fang(张解放) +1 位作者 LIU Yu-lu(刘宇陆) 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2002年第5期549-556,共8页
By using the extended homogeneous balance method, the localized coherent structures are studied. A nonlinear transformation was first established, and then the linearization form was obtained based on the extended hom... By using the extended homogeneous balance method, the localized coherent structures are studied. A nonlinear transformation was first established, and then the linearization form was obtained based on the extended homogeneous balance method for the higher order (2 + 1)-dimensional Broer-Kaup equations. Starting from this linearization form equation, a variable separation solution with the entrance of some arbitrary functions and some arbitrary parameters was constructed. The quite rich localized coherent structures were revealed. This method, which can be generalized to other (2 + I) -dimensional nonlinear evolution equation, is simple and powerful. 展开更多
关键词 higher order Broer-Kaup equation (2+1)-dimension coherent structure homogeneous balance method
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蜂毒肽Protopolybia-MPⅢ及其优化突变体对HSV-1病毒复制周期不同阶段的抑制活性研究
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作者 孙芳 邬理莉 +3 位作者 覃陈虎 罗旭东 陈宗运 叶祥东 《湖北医药学院学报》 CAS 2024年第4期343-348,共6页
目的:研究蜂毒肽Protopolybia-MPⅢ及其优化突变体MPⅢ-3/4/7/10/14在体外对Ⅰ型单纯疱疹病毒(HSV-1)复制周期不同阶段的抑制活性。方法:通过qPCR技术和多肽分阶段孵育平台,检测蜂毒肽Protopoly⁃bia-MPⅢ及5个优化突变体在Vero细胞内对H... 目的:研究蜂毒肽Protopolybia-MPⅢ及其优化突变体MPⅢ-3/4/7/10/14在体外对Ⅰ型单纯疱疹病毒(HSV-1)复制周期不同阶段的抑制活性。方法:通过qPCR技术和多肽分阶段孵育平台,检测蜂毒肽Protopoly⁃bia-MPⅢ及5个优化突变体在Vero细胞内对HSV-1感染的预防作用,以及其对HSV-1复制周期不同阶段的影响。结果:Protopolybia-MPⅢ多肽突变体MPⅢ-4/10/14预处理Vero细胞后去除上清,能限制HSV-1感染。进一步通过多肽抗病毒作用阶段分析实验,发现野生型多肽Protopolybia-MPⅢ主要作用于HSV-1复制周期的吸附阶段,而MPⅢ-3/14主要作用于病毒复制周期的进入/融合以及进入后阶段,MPⅢ-4/7主要作用于病毒复制周期的吸附以及进入/融合阶段,MPⅢ-10主要作用于病毒复制周期的吸附以及进入后阶段。结论:本工作明确了蜂毒肽Protopolybia-MPⅢ及其突变体MPⅢ-3/4/7/10/14对HSV-1复制周期不同阶段的抑制活性,初步阐明了Protopolybia-MPⅢ多肽优化突变体抗病毒活性提高的原因,为胡蜂抗病毒多肽的分子设计和药用研究奠定基础。 展开更多
关键词 胡蜂毒液多肽 优化突变体 Ⅰ型单纯疱疹病毒 复制周期
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Bifurcation of travelling wave solutions for (2+1)-dimension nonlinear dispersive long wave equation
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作者 RONG Ji-hong TANG Sheng-qiang School of Mathematics and Computing Science,Guilin University of Electronic Technology,Guilin541004,China 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2009年第3期291-297,共7页
In this paper,the bifurcation of solitary,kink,anti-kink,and periodic waves for (2+1)-dimension nonlinear dispersive long wave equation is studied by using the bifurcation theory of planar dynamical systems.Bifurca... In this paper,the bifurcation of solitary,kink,anti-kink,and periodic waves for (2+1)-dimension nonlinear dispersive long wave equation is studied by using the bifurcation theory of planar dynamical systems.Bifurcation parameter sets are shown,and under various parameter conditions,all exact explicit formulas of solitary travelling wave solutions and kink travelling wave solutions and periodic travelling wave solutions are listed. 展开更多
关键词 solitary wave kink and anti-kink wave periodic wave (2+1-dimension nonlinear dispersive long wave equation
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