Presented are new images of supernova remnants G114.3±0.3, G116.5＋1.1 and G116.9＋0.2 （CTB 1） at 408 MHz from the Canadian Galactic Plane Survey （CGPS）. We also use the 1420 MHz images from the CGPS in a stu...Presented are new images of supernova remnants G114.3±0.3, G116.5＋1.1 and G116.9＋0.2 （CTB 1） at 408 MHz from the Canadian Galactic Plane Survey （CGPS）. We also use the 1420 MHz images from the CGPS in a study of their 408-1420 MHz spectral indices. The flux densities at 408 MHz and 1420 MHz, corrected for flux densities from compact sources within the SNRs, are 12±6 Jy and 9.8±0.8 Jy for G114.3＋0.3, 15.0±1.5 Jy and 10.6±0.6 Jy for G116.5＋1.1, 15.0＋1.5 Jy and 8.1±0.4 Jy for Gl16.9＋0.2. The integrated flux density-based spectral indices （Sv∝v^-α） are α=0.16±0.41, 0.28±0.09 and 0.49±0.09 for G114.3＋0.3, G116.5＋1.1 and G116.9＋0.2, respectively. Their T-T plot-based spectral indices are 0.68±0.48, 0.28±0.15, and 0.48±0.04, in agreement with the integrated flux density-based spectral indices. New flux densities are derived at 2695 MHz which are significantly larger than previous values. The new 408, 1420 and 2695 MHz flux densities and published values at other frequencies, where images are not available, are fitted after correcting for contributions from compact sources, to derive their multi-frequency spectral indices.展开更多
Prior studies suggested sperm with damaged DNA permits fertilization but may lead to failure of embryo implantation following blastocyst formation. Quantitative correlations between DNA damage and risk of implantation...Prior studies suggested sperm with damaged DNA permits fertilization but may lead to failure of embryo implantation following blastocyst formation. Quantitative correlations between DNA damage and risk of implantation failure have, however, so far not been performed. The aim of this study was to investigate two FSHR gene polymorphisms G919A (Ala307Thr) and A2039G (Asn680Ser) in Eastern Ukrainian Caucasian men with abnormally low fertility. The molecular genetic analysis was performed by real-time PCR, with the level of DNA fragmentation measured by the sperm chromatin dispersion (SCD) method. The relationship between DNA fragmentation in sperm and these genetic polymorphisms was estimated. Compared to homozygotes, the risk of high-level DNA fragmentation (>20%) increased in men up to age 35 years 16-fold for heterozygotes GA of polymorphic variant G919A, 28-fold for homozygotes AA of polymorphic variant G919A;and 16-fold for heterozygotes GG of polymorphic variant A2039G. A statistically significant positive correlation between number of alternative alleles of the FSHR gene in genotype and degree of DNA fragmentation is proved (r<sub>s</sub> = 0.70, P < 0.01).展开更多
文摘Presented are new images of supernova remnants G114.3±0.3, G116.5＋1.1 and G116.9＋0.2 （CTB 1） at 408 MHz from the Canadian Galactic Plane Survey （CGPS）. We also use the 1420 MHz images from the CGPS in a study of their 408-1420 MHz spectral indices. The flux densities at 408 MHz and 1420 MHz, corrected for flux densities from compact sources within the SNRs, are 12±6 Jy and 9.8±0.8 Jy for G114.3＋0.3, 15.0±1.5 Jy and 10.6±0.6 Jy for G116.5＋1.1, 15.0＋1.5 Jy and 8.1±0.4 Jy for Gl16.9＋0.2. The integrated flux density-based spectral indices （Sv∝v^-α） are α=0.16±0.41, 0.28±0.09 and 0.49±0.09 for G114.3＋0.3, G116.5＋1.1 and G116.9＋0.2, respectively. Their T-T plot-based spectral indices are 0.68±0.48, 0.28±0.15, and 0.48±0.04, in agreement with the integrated flux density-based spectral indices. New flux densities are derived at 2695 MHz which are significantly larger than previous values. The new 408, 1420 and 2695 MHz flux densities and published values at other frequencies, where images are not available, are fitted after correcting for contributions from compact sources, to derive their multi-frequency spectral indices.
文摘Prior studies suggested sperm with damaged DNA permits fertilization but may lead to failure of embryo implantation following blastocyst formation. Quantitative correlations between DNA damage and risk of implantation failure have, however, so far not been performed. The aim of this study was to investigate two FSHR gene polymorphisms G919A (Ala307Thr) and A2039G (Asn680Ser) in Eastern Ukrainian Caucasian men with abnormally low fertility. The molecular genetic analysis was performed by real-time PCR, with the level of DNA fragmentation measured by the sperm chromatin dispersion (SCD) method. The relationship between DNA fragmentation in sperm and these genetic polymorphisms was estimated. Compared to homozygotes, the risk of high-level DNA fragmentation (>20%) increased in men up to age 35 years 16-fold for heterozygotes GA of polymorphic variant G919A, 28-fold for homozygotes AA of polymorphic variant G919A;and 16-fold for heterozygotes GG of polymorphic variant A2039G. A statistically significant positive correlation between number of alternative alleles of the FSHR gene in genotype and degree of DNA fragmentation is proved (r<sub>s</sub> = 0.70, P < 0.01).
