目的:探讨水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光对黄褐斑患者疗效及生活质量的影响。方法:选取2018年6月-2019年12月笔者医院收治的黄褐斑女性患者112例,根据患者治疗方案分为研究组55例和对照组57例。对照组采...目的:探讨水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光对黄褐斑患者疗效及生活质量的影响。方法:选取2018年6月-2019年12月笔者医院收治的黄褐斑女性患者112例,根据患者治疗方案分为研究组55例和对照组57例。对照组采用Q开关1064 nm激光治疗,研究组采用水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光治疗,每4周1次,疗程共6个月。比较两组疗效及1年后复发率,比较治疗3、6个月后的黄褐斑生活质量评分量表(Chinesemelasma quality of life scale,Ch-MELASQOL)评分、黄褐斑面积与严重程度指数量表(MASI)评分、满意度评分。结果:治疗6个月后,研究组总有效率为80.00%高于对照组的57.89%。随访1年,研究组无复发,对照组复发率10.53%(6/57)高于研究组(P<0.05)。治疗3、6个月后,研究组的Ch-MELASQOL评分、MASI评分均低于对照组(P<0.05)。研究组治疗后的满意度评分高于对照组(P<0.05)。结论:水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光治疗黄褐斑效果良好,可提高患者生活质量,减少复发。展开更多
Wavelength 1064 nm is one of the most widely used laser wavelengths in industries and science. The high-precision measurement of the refractive index of optical materials at 1064 nm is significant for improving the op...Wavelength 1064 nm is one of the most widely used laser wavelengths in industries and science. The high-precision measurement of the refractive index of optical materials at 1064 nm is significant for improving the optical design. We study the direct measurement of refractive index at 1064nm of lasers, including cMcium fluoride （CaF2）, fused silica and zinc selenide （ZnSe）, whose refractive indices cover a large range from 1.42847 to 2.48272. The measurement system is built based on the quasi-common-path Nd：YAG laser feedback interferometry. The thickness can be measured simultaneously with the refractive index. The results demonstrate that the system has absolute uncertainties of ~10-5 and ~10-4 mm in refractive index and thickness measurement, respectively.展开更多
文摘目的:探讨水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光对黄褐斑患者疗效及生活质量的影响。方法:选取2018年6月-2019年12月笔者医院收治的黄褐斑女性患者112例,根据患者治疗方案分为研究组55例和对照组57例。对照组采用Q开关1064 nm激光治疗,研究组采用水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光治疗,每4周1次,疗程共6个月。比较两组疗效及1年后复发率,比较治疗3、6个月后的黄褐斑生活质量评分量表(Chinesemelasma quality of life scale,Ch-MELASQOL)评分、黄褐斑面积与严重程度指数量表(MASI)评分、满意度评分。结果:治疗6个月后,研究组总有效率为80.00%高于对照组的57.89%。随访1年,研究组无复发,对照组复发率10.53%(6/57)高于研究组(P<0.05)。治疗3、6个月后,研究组的Ch-MELASQOL评分、MASI评分均低于对照组(P<0.05)。研究组治疗后的满意度评分高于对照组(P<0.05)。结论:水光注射透明质酸钠、氨甲环酸、谷胱甘肽联合Q开关1064 nm激光治疗黄褐斑效果良好,可提高患者生活质量,减少复发。
基金Supported by the National Natural Science Foundation of China under Grant No 61036016the Beijing Higher Education Young Elite Teacher Project under Grant No YETP0086
文摘Wavelength 1064 nm is one of the most widely used laser wavelengths in industries and science. The high-precision measurement of the refractive index of optical materials at 1064 nm is significant for improving the optical design. We study the direct measurement of refractive index at 1064nm of lasers, including cMcium fluoride （CaF2）, fused silica and zinc selenide （ZnSe）, whose refractive indices cover a large range from 1.42847 to 2.48272. The measurement system is built based on the quasi-common-path Nd：YAG laser feedback interferometry. The thickness can be measured simultaneously with the refractive index. The results demonstrate that the system has absolute uncertainties of ~10-5 and ~10-4 mm in refractive index and thickness measurement, respectively.
