目的:比较乙型肝炎表面抗原(hepatitis B surface antigen,HBsAg)、胆碱酯酶(cholinesterase,CHE)和吲哚氰绿15min滞留率(indocyanine green retention rate at 15min,ICGR15)在慢性乙型肝炎组、肝硬化代偿组、肝硬化失代偿组的水平,并...目的:比较乙型肝炎表面抗原(hepatitis B surface antigen,HBsAg)、胆碱酯酶(cholinesterase,CHE)和吲哚氰绿15min滞留率(indocyanine green retention rate at 15min,ICGR15)在慢性乙型肝炎组、肝硬化代偿组、肝硬化失代偿组的水平,并研究3者之间的相关性.方法:观察95例慢性乙型肝炎病毒感染患者,按病情分为慢性乙型肝炎组、肝硬化失代偿组和肝硬化代偿组3组.分别检测血清HBsAg、CHE、ICGR15,评价3组间观察指标的差异及相关性.结果:3组间HBsAg水平3.44lgIU/mL±0.55lgIU/mL、3.14lgIU/mL±0.39lgIU/mL、2.76lgIU/mL±0.55lgIU/mL有显著差异(P<0.05);慢性乙型肝炎组与肝硬化失代偿组CHE(6631.37U/L±1907.18U/Lvs4838.51U/L±2134.35U/L,P<0.05)、ICGR15(9.77%±5.57%vs27.69%±13.30%,P<0.05)有显著性差异.相关分析显示各组间CHE和ICGR15均呈负相关,r分别为-0.401、-0.625、-0.444,P<0.05;肝硬化代偿组和失代偿组HBsAg与CHE呈正相关,r分别为0.449、0.407,P<0.05;肝硬化代偿组和失代偿组HBsAg与ICGR15呈负相关,r分别为-0.498、-0.757,P<0.05.结论:随着乙型肝炎向肝硬化进展,HBsAg、CHE水平逐渐降低,ICGR15水平逐渐升高.肝硬化阶段HBsAg与ICGR15呈负相关,与CHE呈正相关,提示HBsAg可能与肝脏残余有效肝细胞量呈正比.且肝硬化阶段CHE和ICGR15呈负相关,因此一定程度上可通过HBsAg、CHE来反映肝硬化患者ICGR15水平.展开更多
Building energy analyses using forecasting optimization strategies are commonly used for predicting TES （thermal energy storage） system performance. These strategies produce perfect optimized cost savings and are no...Building energy analyses using forecasting optimization strategies are commonly used for predicting TES （thermal energy storage） system performance. These strategies produce perfect optimized cost savings and are not typically realized in the real world, unless a safety factor is applied. Rather than show how to improve the industry＇s ability to accurately model and simulate a true TES system design, this paper will show advanced building information strategies and energy management simulation techniques required to truly achieve the ideal optimized cost savings, determined from the TES energy simulation analysis. This paper uses the hospitality industry as a case study, showing the application of simulation and analytical modeling for an optimized partial TES system. As a result building energy managers can make better decisions through the entire building life cycle from the earliest concept model through operation and maintenance.展开更多
文摘目的:比较乙型肝炎表面抗原(hepatitis B surface antigen,HBsAg)、胆碱酯酶(cholinesterase,CHE)和吲哚氰绿15min滞留率(indocyanine green retention rate at 15min,ICGR15)在慢性乙型肝炎组、肝硬化代偿组、肝硬化失代偿组的水平,并研究3者之间的相关性.方法:观察95例慢性乙型肝炎病毒感染患者,按病情分为慢性乙型肝炎组、肝硬化失代偿组和肝硬化代偿组3组.分别检测血清HBsAg、CHE、ICGR15,评价3组间观察指标的差异及相关性.结果:3组间HBsAg水平3.44lgIU/mL±0.55lgIU/mL、3.14lgIU/mL±0.39lgIU/mL、2.76lgIU/mL±0.55lgIU/mL有显著差异(P<0.05);慢性乙型肝炎组与肝硬化失代偿组CHE(6631.37U/L±1907.18U/Lvs4838.51U/L±2134.35U/L,P<0.05)、ICGR15(9.77%±5.57%vs27.69%±13.30%,P<0.05)有显著性差异.相关分析显示各组间CHE和ICGR15均呈负相关,r分别为-0.401、-0.625、-0.444,P<0.05;肝硬化代偿组和失代偿组HBsAg与CHE呈正相关,r分别为0.449、0.407,P<0.05;肝硬化代偿组和失代偿组HBsAg与ICGR15呈负相关,r分别为-0.498、-0.757,P<0.05.结论:随着乙型肝炎向肝硬化进展,HBsAg、CHE水平逐渐降低,ICGR15水平逐渐升高.肝硬化阶段HBsAg与ICGR15呈负相关,与CHE呈正相关,提示HBsAg可能与肝脏残余有效肝细胞量呈正比.且肝硬化阶段CHE和ICGR15呈负相关,因此一定程度上可通过HBsAg、CHE来反映肝硬化患者ICGR15水平.
文摘Building energy analyses using forecasting optimization strategies are commonly used for predicting TES （thermal energy storage） system performance. These strategies produce perfect optimized cost savings and are not typically realized in the real world, unless a safety factor is applied. Rather than show how to improve the industry＇s ability to accurately model and simulate a true TES system design, this paper will show advanced building information strategies and energy management simulation techniques required to truly achieve the ideal optimized cost savings, determined from the TES energy simulation analysis. This paper uses the hospitality industry as a case study, showing the application of simulation and analytical modeling for an optimized partial TES system. As a result building energy managers can make better decisions through the entire building life cycle from the earliest concept model through operation and maintenance.
