2型糖尿病患者合并代谢综合征增加Framingham心血管危险评分

目的：采用Framingham心血管危险评分（FRS）探讨2型糖尿病患者合并代谢综合征对10年心血管疾病风险的影响。方法：入选1708例于2008年5月至2013年4月在浙江大学医学院附属第二医院住院治疗的2型糖尿病患者，测定人体形态学和生化指标。采用ATPm2005亚洲标准诊断代谢综合征，按不同性别分为未合并代谢综合征组和合并代谢综合征组。结果：男女性2型糖尿病合并代谢综合征组腰围、体质量、体质指数、收缩压、舒张压、空腹c肽、总胆固醇、甘油三酯和低密度脂蛋白胆固醇均高于未合并代谢综合征组（均P〈0．05），高密度脂蛋白胆固醇低于未合并代谢综合征组（P〈0．01）。合并代谢综合征组FRS男性[13．0（10．0，15．0）与11．0（9．0，13．0）]、女性[15．0（12．0，18．0）与12．0（6．0，14．8）]和10年心血管风险男性[12．0％（6．0％，20．0％）与8％（5．0％，12．0％）]、女性[3．0％（1．0％，6．0％）与1．0％（0．0％，2．8％）]均高于未合并代谢综合征组（均P〈0．01）。FRS和10年心血管风险随代谢综合征组分增加而增加。结论：2型糖尿病患者合并代谢综合征心血管危险因素增加，进一步增加FRS和10年心血管疾病风险。

2型糖尿病患者107例25羟维生素D3水平检测及相关因素分析

目的:检测2型糖尿病患者25羟维生素D3[25(OH)D3]水平营养状况,探讨25(OH)D3水平与2型糖尿病患者性别、年龄、季节、病程的关系。方法:选择2型糖尿病患者107例,比较不同性别、年龄、季节及病程组25(OH)D3营养状态差异。结果:107例患者血清25(OH)D3水平8.24±6.80ng/ml,男性患者25(OH)D3水平为9.93±8.4mmol/L,女性患者25(OH)D3水平为6.91±5.13mmol/L,女性25(OH)D3水平明显低于男性(P<0.01);不同年龄25(OH)D3水平随年龄增长呈逐渐降低趋势,但无统计学差异;冬季组受试者25(OH)D3水平显著低于春夏季组(P<0.01);不同病程组25(OH)D3水平差异无统计学意义。结论:2型糖尿病患者25(OH)D3缺乏现象普遍存在,尤其是女性患者,应重视糖尿病患者25(OH)D3的补充,特别在冬季需要加强25(OH)D3的监测和补充。

Physical activity,sedentary behaviors,physical fitness,and their relation to health outcomes in youth with type 1 and type 2 diabetes:A review of the epidemiologic literature

Diabetes is a leading chronic disease of childhood and adolescence. In addition to the well-known auto-immune, insulin-dependent diabetes mellitus （type 1 diabetes （T 1D））, the past two decades have witnessed the emergence of type 2 diabetes （T2D） in children and adolescents, which previously was only seen in middle-aged or older adults. One of the key components of diabetes management is physical activity （PA）. The beneficial effects of increased PA and decreased sedentary behavior are extremely important in youth with diabetes because of the markedly increased long-term risk of cardiovascular disease in this population compared to persons without diabetes. This review aims to comprehensively summarize the epidemiologic, observational research published and listed in PubMed between 1970 and 2012 on PA and sedentary behaviors, as well as physical fitness in children and adolescents with T1D and T2D. Additionally, we describe briefly the state of knowledge on perceived barriers of PA in persons with diabetes, with a focus on hypoglycemia. Finally, we provide an overview of the epidemiological literature pertaining to health benefits of increased PA in youth with TID and T2D and briefly discuss the topic of exercise-related hypoglycemia, Copyright ~ 2012, Shanghai University of Sport. Production and hosting by Elsevier B.V. All rights reserved.

Epidemiological Investigation and Genetic Characterization of Type 2 PCV2 （Type 2 Porcine Circovirus） in Mexican Commercial Herds

PCV2 （Porcine circovirus type 2） is considered as the essential infectious agent of PMWS （post weaning multisystemic wasting syndrome） in pigs. Serological studies have shown that the virus is ubiquitous. Currently, there are many reports about the epidemiology and genetic characteristics of this virus around the world, but in Mexico it has not been studied. More than 3,500 samples of serum, rectal swabs, tissues and semen of 34 Mexican porcine farms from 10 important producer regions were analyzed by PCR. Results show that 97% of the farms were positive. Both genotypes, PCV2a and PCV2b were detected. It also found that the most prevalent genotype in Mexico is PCV2b. Regarding to amino acid sequence; three major heterogenic regions were present in the positions 59-91,123-136 and 185-210.

2005-2009年2型糖尿病住院患者调查

目的了解2型糖尿病发病动态,为临床治疗及医疗资源合理配置提供参考依据。方法对大连市第五人民医院2005-2009年2型糖尿病数据资料进行整理、统计、分析。结果 2型糖尿病住院人数逐年增加,2型糖尿病合并并发症的患者数量逐年增加。结论医院应密切关注病房患者数量的变化,调整病房规模,合理分配医疗资源,为患者提供更高质量的医疗服务。

南京中医药大学教职工空腹血糖受损情况分析

目的分析南京中医药大学教职工的空腹血糖受损(IFG)情况,为高校教职工健康保健并采取合理措施提供依据。方法选择2010年度本校参加健康体检的925名教职工作为研究对象,测量空腹血糖,并对检测结果进行统计分析。结果 925名体检者中,空腹血糖受损检出率为9.2%,其中男性11.9%,女性7.2%,差异有统计学意义(P<0.05);且空腹血糖受损检出率随年龄增加而升高,差异有统计学意义(P<0.01)。结论教职工空腹血糖受损检出率较高,且随年龄增加而升高,提示在高校教职工中应重视IFG的防治,预防2型糖尿病发生。