In this study, the vaporization ratio of the 2-μm laser in the prostatic tissue with benign prostatic hyperplasia was examined in vitro, to explore a technique to estimate the clearance rate of prostatic tissue durin...In this study, the vaporization ratio of the 2-μm laser in the prostatic tissue with benign prostatic hyperplasia was examined in vitro, to explore a technique to estimate the clearance rate of prostatic tissue during the transurethral vaporesection of the prostate. A total of 9 fresh prostatic tissue specimens were obtained by open surgery and the wet weight of the prostatic tissue were measured immediately after the sample collection. Under the simulated conditions of transurethral vaporesection of the prostate by 2-μm laser, each prostate gland was completely vaporesected into fragments with a diameter of less than 1.0 cm in vitro tissue were collected and measured. Then After the vaporesection, the whole fragments of prostatic the lost weight of prostatic tissue, the weight of the collected prostatic tissue and the ratio of the lost weight of prostatic tissue to the wet weight of the prostate glandular organ specimen were calculated. The correlation between the weight of collected prostatic tissue and the weight of the whole glandular organ was analyzed. All the experimental procedures were carried out by one operator. Wet weight of the prostatic gland specimen and the weight of the harvested prostatic tissues after the procedure were recorded. With respect to the wet weight of prostate gland specimen, the percentage of the weight of collected prostatic tissue was （34.45±1.51） %, and the percentage of the lost weight of prostatic tissue was （65.55±1.51）%. Satisfactory linear relationship was observed between the weight of collected prostatic tissue and the wet weight of prostate gland specimen [y=3.245x=6.475 （t=15.097, P=0.000）]. It is concluded that under the simulated conditions of transurethral vaporesection of the prostate by 2-μm laser, the vaporization ratio of prostatic tissue can be calculated on the basis of the weight of collected prostatic tissue, and thereby the clearance of prostatic tissue during the formal operation by 2-μm laser could be quantitatively determined.展开更多
Highly transparent Yb,Ho doped（YLa）2O3 ceramic was fabricated by conventional ceramic processing with nanopowders.The absorption and emission spectra of the ceramic was investigated.The energy transfer mechanism bet...Highly transparent Yb,Ho doped（YLa）2O3 ceramic was fabricated by conventional ceramic processing with nanopowders.The absorption and emission spectra of the ceramic was investigated.The energy transfer mechanism between Yb3＋ and Ho3＋ was also discussed.The strong emission band around 2 μm indicated that the Yb-Ho：（Y 0.90 La 0.10）2O3 transparent ceramic is a promising gain medium for the generation of 2 μm laser emissions.The laser operation of Yb-Ho co-doped（YLa）2O3 ceramic at 2.1 μm is first reported.展开更多
目的:比较2μm激光、钬激光与经尿道膀胱肿瘤切除术(transurethral resection of the bladder tumor,TURBT)治疗非肌层浸润性膀胱癌(non-muscle invasive bladder cancer,NMIBC)的有效性和安全性。方法:2011年6月至2013年6月期间,210例...目的:比较2μm激光、钬激光与经尿道膀胱肿瘤切除术(transurethral resection of the bladder tumor,TURBT)治疗非肌层浸润性膀胱癌(non-muscle invasive bladder cancer,NMIBC)的有效性和安全性。方法:2011年6月至2013年6月期间,210例初诊为NMIBC患者被随机分到2μm激光手术组(n=70)、钬激光手术组(n=70)和TURBT手术组(n=70),记录手术时间、相关并发症、术后膀胱冲洗情况、留置导尿时间、住院时间。术后随访2年,定期行表柔比星膀胱灌注化疗和膀胱镜检查,记录膀胱肿瘤复发情况。结果:所有患者均顺利接受相应手术,2μm激光组、钬激光组和TURBT组的平均手术时间和输血率无统计学差异(P>0.05),TURBT组术中闭孔神经反射和膀胱穿孔发生率、术后需要膀胱冲洗病例、留置导尿时间、住院时间均高于2μm激光组与钬激光组,差异有统计学差异(P<0.05),且2μm激光组与钬激光组之间比较无明显差异。术后两年的随访研究中,共有24名患者失访,三组患者肿瘤复发率无统计学差异(P>0.05)。结论:2μm激光和钬激光在治疗NMIBC上优于传统的TURBT,2μm激光与钬激光两者之间临床疗效比较无明显差异。且TURBT、2μm激光和钬激光在术后肿瘤复发方面并无差异,下一步需要更多的病例数和更长的随访时间来验证本研究结果。展开更多
目的：比较经尿道2μm激光前列腺剜除术及前列腺电切术治疗大体积良性前列腺增生的疗效及安全性。方法收集2011～2013年间79例在我院手术治疗的前列腺体积＞80 m L患者的临床资料，其中经尿道2μm激光前列腺剜除术45例，前列腺电切术34...目的：比较经尿道2μm激光前列腺剜除术及前列腺电切术治疗大体积良性前列腺增生的疗效及安全性。方法收集2011～2013年间79例在我院手术治疗的前列腺体积＞80 m L患者的临床资料，其中经尿道2μm激光前列腺剜除术45例，前列腺电切术34例，比较两组病例的手术时间、切除的腺体组织重量、术中出血量、持续膀胱冲洗时间、留置尿管时间、手术并发症及手术前后最大尿流率（Qmax）、残余尿量（PVRU）、国际前列腺症状评分（IPSS）、以及生活质量评分（QOL）情况。结果79例患者均一次手术成功，两组患者手术时间、术中出血量、持续膀胱冲洗时间、留置尿管时间比较，差异具有统计学意义（P＜0．05）；两组术中所切除的前列腺体组织重量无统计学差异（P＞0．05）；两组术后发生暂时性尿失禁、泌尿系感染、二次出血的例数比较，差异具有统计学意义（P＜0．05），两组均无死亡病例；两组患者Qmax、PVRU、IPSS及QOL评分较术前均有明显改善（P＜0．05），但两组间比较差异均无统计学意义（P＞0．05）。结论对于前列腺体积＞80 mL的大体积BPH患者，在做好围手术期准备、术者经验丰富的情况下，经尿道2μm激光前列腺剜除术和T U RP均有明显的临床效果，特别是经尿道2μm激光前列腺剜除术更具有术中出血少、安全性高、并发症少等优点。展开更多
基金supported by a grant from "The 11th Five-year Plan of Scientific Research" of People’s Liberation Army of China (No. 06MA297)
文摘In this study, the vaporization ratio of the 2-μm laser in the prostatic tissue with benign prostatic hyperplasia was examined in vitro, to explore a technique to estimate the clearance rate of prostatic tissue during the transurethral vaporesection of the prostate. A total of 9 fresh prostatic tissue specimens were obtained by open surgery and the wet weight of the prostatic tissue were measured immediately after the sample collection. Under the simulated conditions of transurethral vaporesection of the prostate by 2-μm laser, each prostate gland was completely vaporesected into fragments with a diameter of less than 1.0 cm in vitro tissue were collected and measured. Then After the vaporesection, the whole fragments of prostatic the lost weight of prostatic tissue, the weight of the collected prostatic tissue and the ratio of the lost weight of prostatic tissue to the wet weight of the prostate glandular organ specimen were calculated. The correlation between the weight of collected prostatic tissue and the weight of the whole glandular organ was analyzed. All the experimental procedures were carried out by one operator. Wet weight of the prostatic gland specimen and the weight of the harvested prostatic tissues after the procedure were recorded. With respect to the wet weight of prostate gland specimen, the percentage of the weight of collected prostatic tissue was （34.45±1.51） %, and the percentage of the lost weight of prostatic tissue was （65.55±1.51）%. Satisfactory linear relationship was observed between the weight of collected prostatic tissue and the wet weight of prostate gland specimen [y=3.245x=6.475 （t=15.097, P=0.000）]. It is concluded that under the simulated conditions of transurethral vaporesection of the prostate by 2-μm laser, the vaporization ratio of prostatic tissue can be calculated on the basis of the weight of collected prostatic tissue, and thereby the clearance of prostatic tissue during the formal operation by 2-μm laser could be quantitatively determined.
基金Project supported by the National Natural Science Foundation of China (Grant No. 60578041)the Sciences and Technology Commission Foundation of Shanghai,China (Grant No. 08520707300)+1 种基金the Key Basic Research Project of Science and Technology Commission of Shanghai,China (Grant No. 09JC1406500)the Graduate Student Innovation Fund of Shanghai University,China (Grant No. SHUCX120058)
文摘Highly transparent Yb,Ho doped（YLa）2O3 ceramic was fabricated by conventional ceramic processing with nanopowders.The absorption and emission spectra of the ceramic was investigated.The energy transfer mechanism between Yb3＋ and Ho3＋ was also discussed.The strong emission band around 2 μm indicated that the Yb-Ho：（Y 0.90 La 0.10）2O3 transparent ceramic is a promising gain medium for the generation of 2 μm laser emissions.The laser operation of Yb-Ho co-doped（YLa）2O3 ceramic at 2.1 μm is first reported.
文摘目的:比较2μm激光、钬激光与经尿道膀胱肿瘤切除术(transurethral resection of the bladder tumor,TURBT)治疗非肌层浸润性膀胱癌(non-muscle invasive bladder cancer,NMIBC)的有效性和安全性。方法:2011年6月至2013年6月期间,210例初诊为NMIBC患者被随机分到2μm激光手术组(n=70)、钬激光手术组(n=70)和TURBT手术组(n=70),记录手术时间、相关并发症、术后膀胱冲洗情况、留置导尿时间、住院时间。术后随访2年,定期行表柔比星膀胱灌注化疗和膀胱镜检查,记录膀胱肿瘤复发情况。结果:所有患者均顺利接受相应手术,2μm激光组、钬激光组和TURBT组的平均手术时间和输血率无统计学差异(P>0.05),TURBT组术中闭孔神经反射和膀胱穿孔发生率、术后需要膀胱冲洗病例、留置导尿时间、住院时间均高于2μm激光组与钬激光组,差异有统计学差异(P<0.05),且2μm激光组与钬激光组之间比较无明显差异。术后两年的随访研究中,共有24名患者失访,三组患者肿瘤复发率无统计学差异(P>0.05)。结论:2μm激光和钬激光在治疗NMIBC上优于传统的TURBT,2μm激光与钬激光两者之间临床疗效比较无明显差异。且TURBT、2μm激光和钬激光在术后肿瘤复发方面并无差异,下一步需要更多的病例数和更长的随访时间来验证本研究结果。
文摘目的：比较经尿道2μm激光前列腺剜除术及前列腺电切术治疗大体积良性前列腺增生的疗效及安全性。方法收集2011～2013年间79例在我院手术治疗的前列腺体积＞80 m L患者的临床资料，其中经尿道2μm激光前列腺剜除术45例，前列腺电切术34例，比较两组病例的手术时间、切除的腺体组织重量、术中出血量、持续膀胱冲洗时间、留置尿管时间、手术并发症及手术前后最大尿流率（Qmax）、残余尿量（PVRU）、国际前列腺症状评分（IPSS）、以及生活质量评分（QOL）情况。结果79例患者均一次手术成功，两组患者手术时间、术中出血量、持续膀胱冲洗时间、留置尿管时间比较，差异具有统计学意义（P＜0．05）；两组术中所切除的前列腺体组织重量无统计学差异（P＞0．05）；两组术后发生暂时性尿失禁、泌尿系感染、二次出血的例数比较，差异具有统计学意义（P＜0．05），两组均无死亡病例；两组患者Qmax、PVRU、IPSS及QOL评分较术前均有明显改善（P＜0．05），但两组间比较差异均无统计学意义（P＞0．05）。结论对于前列腺体积＞80 mL的大体积BPH患者，在做好围手术期准备、术者经验丰富的情况下，经尿道2μm激光前列腺剜除术和T U RP均有明显的临床效果，特别是经尿道2μm激光前列腺剜除术更具有术中出血少、安全性高、并发症少等优点。
