Different effects of valproate on methamphetamine-and cocaine-induced behavioral sensitization in mice

Multiple intermittent administration of psychostimulants induces a behavioral sensitization, which is characterized by the augmentation of locomotor activity and stereotyped behavior, even after their long-term withdrawal. This kind of behavioral effects is thought to serve as a useful animal model that mimics the behavioral responses in drug craving.

中枢神经系统疾病治疗药物最新动态

FDA批准aripiprazole作为精神稳定剂的辅助药物用于治疗Ⅰ型双向情感障碍 FDA批准百时美．施贵宝和大冢制药公司的aripiprazole（Abilify）作为精神稳定剂锂或2-丙基戊酸钠的辅助药物用于维持秩疗Ⅰ型双向情感障碍。