Fourteen unreported 2-amino-4H-imidazol-4-ones 4 were rapidly synthesized by a new parallel synthetic method, which included aza-Wittig reaction of iminophosphorane 1 with phenyl isocynate to give carbodiimide 2 and s...Fourteen unreported 2-amino-4H-imidazol-4-ones 4 were rapidly synthesized by a new parallel synthetic method, which included aza-Wittig reaction of iminophosphorane 1 with phenyl isocynate to give carbodiimide 2 and subsequent reaction of 2 with various amines in a parallel fashion. The structure of compound 4 was confirmed by means of 1H NMR, MS and IR. The configuration of compound 4b was determined as in Z form since the coupling constant 3J( 13C, 1H) between the carbonyl carbon and the olefinic hydrogen was 5.6 Hz.展开更多
Six title compounds were synthesized by the reaction of salicylic acid and 4 substituted phenylenediamine in the presence of pyridine and POCl 3 by microwave irradiation.The reactions took place easily with good yields.
Fifteen substituted 2,4,5-triaryl-1H-imidazoles are synthesized by three-component and one-pot reaction of aromatic aldehydes,benzil and ammonium acetate under microwave irradiation,solvent and catalyst-free condition...Fifteen substituted 2,4,5-triaryl-1H-imidazoles are synthesized by three-component and one-pot reaction of aromatic aldehydes,benzil and ammonium acetate under microwave irradiation,solvent and catalyst-free conditions.The products are identified by IR,1HNMR,13CNMR and MS.The method is in accordance with the requirement of green chemistry.展开更多
Five 2 methyl 5 nitroimidazol derivatives were synthesized primarily from oxalaldehyde,ethanal via cyclization,nitration,esterification.The strutures of these compounds have been examined and confirmed by IR, 1H NMR,U...Five 2 methyl 5 nitroimidazol derivatives were synthesized primarily from oxalaldehyde,ethanal via cyclization,nitration,esterification.The strutures of these compounds have been examined and confirmed by IR, 1H NMR,UV spectra as well as elementary analysis.展开更多
文摘Fourteen unreported 2-amino-4H-imidazol-4-ones 4 were rapidly synthesized by a new parallel synthetic method, which included aza-Wittig reaction of iminophosphorane 1 with phenyl isocynate to give carbodiimide 2 and subsequent reaction of 2 with various amines in a parallel fashion. The structure of compound 4 was confirmed by means of 1H NMR, MS and IR. The configuration of compound 4b was determined as in Z form since the coupling constant 3J( 13C, 1H) between the carbonyl carbon and the olefinic hydrogen was 5.6 Hz.
文摘Six title compounds were synthesized by the reaction of salicylic acid and 4 substituted phenylenediamine in the presence of pyridine and POCl 3 by microwave irradiation.The reactions took place easily with good yields.
文摘Fifteen substituted 2,4,5-triaryl-1H-imidazoles are synthesized by three-component and one-pot reaction of aromatic aldehydes,benzil and ammonium acetate under microwave irradiation,solvent and catalyst-free conditions.The products are identified by IR,1HNMR,13CNMR and MS.The method is in accordance with the requirement of green chemistry.
文摘Five 2 methyl 5 nitroimidazol derivatives were synthesized primarily from oxalaldehyde,ethanal via cyclization,nitration,esterification.The strutures of these compounds have been examined and confirmed by IR, 1H NMR,UV spectra as well as elementary analysis.
