Aim To determine the effect of local simvastatin application on the mRNA expression level of transforming growth factor-β1 （TGF-β1）, bone morphogenetic protein-2 （BMP-2） and vascular endothelial growth factor （...Aim To determine the effect of local simvastatin application on the mRNA expression level of transforming growth factor-β1 （TGF-β1）, bone morphogenetic protein-2 （BMP-2） and vascular endothelial growth factor （VEGF） in the tooth sockets of rat. Methodology Forty-eight male Wistar rats were randomly divided into experimental and control groups （n=24）. Polylactic acid/polyglycolic acid copolymer carriers, with or without simvastatin, were implanted into extraction sockets of right mandibular incisors. The expression of TGF-β1, BMP-2 and VEGF mRNA was determined by in situ hybridization in the tooth extraction socket at five days, one week, two weeks and four weeks after implantation. Results The fusiform stroma cells in the tooth extraction socket began to express TGF-β1, BMP-2 and VEGF mRNA in both experimental and control groups from one week after tooth extraction until the end of experiment. The expression of TGF-131 and BMP-2 mRNA in the experimental group was significantly up-regulated after one, two and four weeks, and expression of VEGF mRNA was significantly increased after one and two weeks compared with that in the control group. Conclusion The findings indicate that local administration of simvastatin can influence alveolar bone remodeling by regulating the expression of a school of growth factors which are crucial to osteogenesis in the tooth extraction socket.展开更多
It is revealed that the dynamic stability of 2-D recursive continuous-discrete systems with interval parameters involves the problem of robust Hurwitz-Schur stability of bivariate polynomials family. It is proved that...It is revealed that the dynamic stability of 2-D recursive continuous-discrete systems with interval parameters involves the problem of robust Hurwitz-Schur stability of bivariate polynomials family. It is proved that the Hurwitz-Schur stability of the denominator polynomials of the systems is necessary and sufficient for the asymptotic stability of the 2-D hybrid systems. The 2-D hybrid transformation, i. e. 2-D Laplace-Z transformation, has been proposed to solve the stability analysis of the 2-D continuous-discrete systems, to get the 2-D hybrid transfer functions of the systems. The edge test for the Hurwitz-Schur stability of interval bivariate polynomials is introduced. The Hurwitz-Schur stability of the interval family of 2-D polynomials can be guaranteed by the stability of its finite edge polynomials of the family. An algorithm about the stability test of edge polynomials is given.展开更多
In the traditional incremental analysis update(IAU)process,all analysis increments are treated as constant forcing in a model’s prognostic equations over a certain time window.This approach effectively reduces high-f...In the traditional incremental analysis update(IAU)process,all analysis increments are treated as constant forcing in a model’s prognostic equations over a certain time window.This approach effectively reduces high-frequency oscillations introduced by data assimilation.However,as different scales of increments have unique evolutionary speeds and life histories in a numerical model,the traditional IAU scheme cannot fully meet the requirements of short-term forecasting for the damping of high-frequency noise and may even cause systematic drifts.Therefore,a multi-scale IAU scheme is proposed in this paper.Analysis increments were divided into different scale parts using a spatial filtering technique.For each scale increment,the optimal relaxation time in the IAU scheme was determined by the skill of the forecasting results.Finally,different scales of analysis increments were added to the model integration during their optimal relaxation time.The multi-scale IAU scheme can effectively reduce the noise and further improve the balance between large-scale and small-scale increments in the model initialization stage.To evaluate its performance,several numerical experiments were conducted to simulate the path and intensity of Typhoon Mangkhut(2018)and showed that:(1)the multi-scale IAU scheme had an obvious effect on noise control at the initial stage of data assimilation;(2)the optimal relaxation time for large-scale and small-scale increments was estimated as 6 h and 3 h,respectively;(3)the forecast performance of the multi-scale IAU scheme in the prediction of Typhoon Mangkhut(2018)was better than that of the traditional IAU scheme.The results demonstrate the superiority of the multi-scale IAU scheme.展开更多
Sea ice surface roughness(SIR)affects the energy transfer between the atmosphere and the ocean,and it is also an important indicator for sea ice characteristics.To obtain a small-scale SIR with high spatial resolution...Sea ice surface roughness(SIR)affects the energy transfer between the atmosphere and the ocean,and it is also an important indicator for sea ice characteristics.To obtain a small-scale SIR with high spatial resolution,a novel method is proposed to retrieve SIR from Sentinel-1 synthetic aperture radar(SAR)images,utilizing an ensemble learning method.Firstly,the two-dimensional continuous wavelet transform is applied to obtain the spatial information of sea ice,including the scale and direction of ice patterns.Secondly,a model is developed using the Adaboost Regression model to establish a relationship among SIR,radar backscatter and the spatial information of sea ice.The proposed method is validated by using the SIR retrieved from SAR images and comparing it to the measurements obtained by the Airborne Topographic Mapper(ATM)in the summer Beaufort Sea.The determination of coefficient,mean absolute error,root-mean-square error and mean absolute percentage error of the testing data are 0.91,1.71 cm,2.82 cm,and 36.37%,respectively,which are reasonable.Moreover,K-fold cross-validation and learning curves are analyzed,which also demonstrate the method’s applicability in retrieving SIR from SAR images.展开更多
This study presents a novel two-step approach to assess plate-like structural laminar damages,particularly for delamination damage detection of composite structures.Firstly,a 2-D continuous wavelet transform is employ...This study presents a novel two-step approach to assess plate-like structural laminar damages,particularly for delamination damage detection of composite structures.Firstly,a 2-D continuous wavelet transform is employed to identify the damage location and sizes from vibration curvature data.An inverse method is subsequently then used to determine the bending stiffness reduction ratio along a specified direction,enabling the quantification of the delamination severity.The method employed in this study is an extension of the one-dimensional inverse method developed in a previous work of the authors.The applicability of the two-step inverse approach is demonstrated in a simulation analysis and by an experimental study on a cantilever composite plate containing a single delamination.The inverse method is shown to have the capacity to reveal the detailed damage information of delamination within a constrained searching space and can be used to determine the effective flexural stiffness of composite plate structures,even in cases of complex delamination damage.展开更多
A 3-Dimensional computer aided garment design (CAGD) system has been developed andimplemented on a high-performance workstation. We studied various approaches to the func-tional modelling of garment designs for the sy...A 3-Dimensional computer aided garment design (CAGD) system has been developed andimplemented on a high-performance workstation. We studied various approaches to the func-tional modelling of garment designs for the system. According to the characteristic data of a hu-man body, the models of human body and the garment are displayed on the screen, then we canmodify the garment with various styles and different sizes. The system can transform the 3-Dgarment to the 2-D pieces. The system has improved design efficiency. Various potential alterna-tives and improvement of the system have also been studied and explored.展开更多
In this paper,we address the frequency estimator for 2-dimensional(2-D)complex sinusoids in the presence of white Gaussian noise.With the use of the sinc function model of the discrete Fourier transform(DFT)coefficien...In this paper,we address the frequency estimator for 2-dimensional(2-D)complex sinusoids in the presence of white Gaussian noise.With the use of the sinc function model of the discrete Fourier transform(DFT)coefficients on the input data,a fast and accurate frequency estimator is devised,where only the DFT coefficient with the highest magnitude and its four neighbors are required.Variance analysis is also included to investigate the accuracy of the proposed algorithm.Simulation results are conducted to demonstrate the superiority of the developed scheme,in terms of the estimation performance and computational complexity.展开更多
Liangyoupeijiu is a two-parental-line, and Shanyou63 is a three-parental-line hybrid rice （Oryza sativa L.）. Although both belong to the indica subspecies, they have obvious differences with respect to morphology, p...Liangyoupeijiu is a two-parental-line, and Shanyou63 is a three-parental-line hybrid rice （Oryza sativa L.）. Although both belong to the indica subspecies, they have obvious differences with respect to morphology, physiology and grain quality. Variations in endosperm protein compositions were studied by comparing the 2-D electrophoresis （2-DE） maps for these two cultivars of hybrid rice. After matrix-assisted laser desorption/ionization time of flight mass spectrometry （MALDI-TOF/MS） analysis, a 21-kDa precursor of 19- kDa globulin was identified as the major storage protein for both cultivars. Some isoforms of peroxiredoxin and seed maturation protein were found to only exist in Shanyou63, whereas aldose reductase and starch granule-bound starch synthase were only detected in Liangyoupeijiu. These data might provide a foundation for further comparative studies of these two cultivars of hybrid rice.展开更多
Implementation of efficient vibration control schemes for seismically excited structures is becoming more and more important in recent years.In this study,the influence of different control schemes on the dynamic perf...Implementation of efficient vibration control schemes for seismically excited structures is becoming more and more important in recent years.In this study,the influence of different control schemes on the dynamic performance of a frame structure excited by El Centro wave,with an emphasis on reaching law based control strategies,is examined.Reaching law refers to the reachable problem and criteria for the sliding state of a control system.Three reaching laws are designed to present different sliding mode control strategies by incorporating a state space model that describes structural dynamic characteristics of a frame structure.Both intact and damaged structures are studied by using the aforementioned control strategies.The influence of different structural damage extents,control locations and reaching law based control methods are further investigated.The results show that the structure can be well controlled using the sliding mode strategy when the induced structural damage extent does not exceed the standard percentage for considering the structure was damaged,which is 20%reduction in structure stiffness,as reported in the literature.The control effectiveness is more satisfactory if the control location is the same as the direction of external excitation.Furthermore,to study the chattering phenomenon of the sliding mode control method,approximation and detail components extracted from the phase plots of the sliding mode control system are compared via wavelet transform at different scales.The results show that for the same type of control law,the system behaves with similar chattering phenomenon.展开更多
Among existing remote sensing applications, land-based X-band radar is an effective technique to monitor the wave fields, and spatial wave information could be obtained from the radar images. Two-dimensional Fourier T...Among existing remote sensing applications, land-based X-band radar is an effective technique to monitor the wave fields, and spatial wave information could be obtained from the radar images. Two-dimensional Fourier Transform （2-D FT） is the common algorithm to derive the spectra of radar images. However, the wave field in the nearshore area is highly non-homogeneous due to wave refraction, shoaling, and other coastal mechanisms. When applied in nearshore radar images, 2-D FT would lead to ambiguity of wave characteristics in wave number domain. In this article, we introduce two-dimensional Wavelet Transform （2-D WT） to capture the non-homogeneity of wave fields from nearshore radar images. The results show that wave number spectra by 2-D WT at six parallel space locations in the given image clearly present the shoaling of nearshore waves. Wave number of the peak wave energy is increasing along the inshore direction, and dominant direction of the spectra changes from South South West （SSW） to West South West （WSW）. To verify the results of 2-D WT, wave shoaling in radar images is calculated based on dispersion relation. The theoretical calculation results agree with the results of 2-D WT on the whole. The encouraging performance of 2-D WT indicates its strong capability of revealing the non-homogeneity of wave fields in nearshore X-band radar images.展开更多
基金supported by grants from the National Nature Science foundation of China(Grant Nos.30872912 and 30830108)
文摘Aim To determine the effect of local simvastatin application on the mRNA expression level of transforming growth factor-β1 （TGF-β1）, bone morphogenetic protein-2 （BMP-2） and vascular endothelial growth factor （VEGF） in the tooth sockets of rat. Methodology Forty-eight male Wistar rats were randomly divided into experimental and control groups （n=24）. Polylactic acid/polyglycolic acid copolymer carriers, with or without simvastatin, were implanted into extraction sockets of right mandibular incisors. The expression of TGF-β1, BMP-2 and VEGF mRNA was determined by in situ hybridization in the tooth extraction socket at five days, one week, two weeks and four weeks after implantation. Results The fusiform stroma cells in the tooth extraction socket began to express TGF-β1, BMP-2 and VEGF mRNA in both experimental and control groups from one week after tooth extraction until the end of experiment. The expression of TGF-131 and BMP-2 mRNA in the experimental group was significantly up-regulated after one, two and four weeks, and expression of VEGF mRNA was significantly increased after one and two weeks compared with that in the control group. Conclusion The findings indicate that local administration of simvastatin can influence alveolar bone remodeling by regulating the expression of a school of growth factors which are crucial to osteogenesis in the tooth extraction socket.
基金This project was supported by National Natural Science Foundation of China (69971002).
文摘It is revealed that the dynamic stability of 2-D recursive continuous-discrete systems with interval parameters involves the problem of robust Hurwitz-Schur stability of bivariate polynomials family. It is proved that the Hurwitz-Schur stability of the denominator polynomials of the systems is necessary and sufficient for the asymptotic stability of the 2-D hybrid systems. The 2-D hybrid transformation, i. e. 2-D Laplace-Z transformation, has been proposed to solve the stability analysis of the 2-D continuous-discrete systems, to get the 2-D hybrid transfer functions of the systems. The edge test for the Hurwitz-Schur stability of interval bivariate polynomials is introduced. The Hurwitz-Schur stability of the interval family of 2-D polynomials can be guaranteed by the stability of its finite edge polynomials of the family. An algorithm about the stability test of edge polynomials is given.
基金jointly sponsored by the Shenzhen Science and Technology Innovation Commission (Grant No. KCXFZ20201221173610028)the key program of the National Natural Science Foundation of China (Grant No. 42130605)
文摘In the traditional incremental analysis update(IAU)process,all analysis increments are treated as constant forcing in a model’s prognostic equations over a certain time window.This approach effectively reduces high-frequency oscillations introduced by data assimilation.However,as different scales of increments have unique evolutionary speeds and life histories in a numerical model,the traditional IAU scheme cannot fully meet the requirements of short-term forecasting for the damping of high-frequency noise and may even cause systematic drifts.Therefore,a multi-scale IAU scheme is proposed in this paper.Analysis increments were divided into different scale parts using a spatial filtering technique.For each scale increment,the optimal relaxation time in the IAU scheme was determined by the skill of the forecasting results.Finally,different scales of analysis increments were added to the model integration during their optimal relaxation time.The multi-scale IAU scheme can effectively reduce the noise and further improve the balance between large-scale and small-scale increments in the model initialization stage.To evaluate its performance,several numerical experiments were conducted to simulate the path and intensity of Typhoon Mangkhut(2018)and showed that:(1)the multi-scale IAU scheme had an obvious effect on noise control at the initial stage of data assimilation;(2)the optimal relaxation time for large-scale and small-scale increments was estimated as 6 h and 3 h,respectively;(3)the forecast performance of the multi-scale IAU scheme in the prediction of Typhoon Mangkhut(2018)was better than that of the traditional IAU scheme.The results demonstrate the superiority of the multi-scale IAU scheme.
基金The National Key Research and Development Program of China under contract No.2021YFC2803301the National Natural Science Foundation of China under contract No.41977302+2 种基金the National Natural Science Youth Foundation of China under contract No.41506199the Natural Science Youth Foundation of Jiangsu Province under contrant No.BK20150905the Science and Technology Project of China Huaneng Group Co.,Ltd.under contract No.HNKJ20-H66.
文摘Sea ice surface roughness(SIR)affects the energy transfer between the atmosphere and the ocean,and it is also an important indicator for sea ice characteristics.To obtain a small-scale SIR with high spatial resolution,a novel method is proposed to retrieve SIR from Sentinel-1 synthetic aperture radar(SAR)images,utilizing an ensemble learning method.Firstly,the two-dimensional continuous wavelet transform is applied to obtain the spatial information of sea ice,including the scale and direction of ice patterns.Secondly,a model is developed using the Adaboost Regression model to establish a relationship among SIR,radar backscatter and the spatial information of sea ice.The proposed method is validated by using the SIR retrieved from SAR images and comparing it to the measurements obtained by the Airborne Topographic Mapper(ATM)in the summer Beaufort Sea.The determination of coefficient,mean absolute error,root-mean-square error and mean absolute percentage error of the testing data are 0.91,1.71 cm,2.82 cm,and 36.37%,respectively,which are reasonable.Moreover,K-fold cross-validation and learning curves are analyzed,which also demonstrate the method’s applicability in retrieving SIR from SAR images.
文摘This study presents a novel two-step approach to assess plate-like structural laminar damages,particularly for delamination damage detection of composite structures.Firstly,a 2-D continuous wavelet transform is employed to identify the damage location and sizes from vibration curvature data.An inverse method is subsequently then used to determine the bending stiffness reduction ratio along a specified direction,enabling the quantification of the delamination severity.The method employed in this study is an extension of the one-dimensional inverse method developed in a previous work of the authors.The applicability of the two-step inverse approach is demonstrated in a simulation analysis and by an experimental study on a cantilever composite plate containing a single delamination.The inverse method is shown to have the capacity to reveal the detailed damage information of delamination within a constrained searching space and can be used to determine the effective flexural stiffness of composite plate structures,even in cases of complex delamination damage.
文摘A 3-Dimensional computer aided garment design (CAGD) system has been developed andimplemented on a high-performance workstation. We studied various approaches to the func-tional modelling of garment designs for the system. According to the characteristic data of a hu-man body, the models of human body and the garment are displayed on the screen, then we canmodify the garment with various styles and different sizes. The system can transform the 3-Dgarment to the 2-D pieces. The system has improved design efficiency. Various potential alterna-tives and improvement of the system have also been studied and explored.
文摘In this paper,we address the frequency estimator for 2-dimensional(2-D)complex sinusoids in the presence of white Gaussian noise.With the use of the sinc function model of the discrete Fourier transform(DFT)coefficients on the input data,a fast and accurate frequency estimator is devised,where only the DFT coefficient with the highest magnitude and its four neighbors are required.Variance analysis is also included to investigate the accuracy of the proposed algorithm.Simulation results are conducted to demonstrate the superiority of the developed scheme,in terms of the estimation performance and computational complexity.
文摘Liangyoupeijiu is a two-parental-line, and Shanyou63 is a three-parental-line hybrid rice （Oryza sativa L.）. Although both belong to the indica subspecies, they have obvious differences with respect to morphology, physiology and grain quality. Variations in endosperm protein compositions were studied by comparing the 2-D electrophoresis （2-DE） maps for these two cultivars of hybrid rice. After matrix-assisted laser desorption/ionization time of flight mass spectrometry （MALDI-TOF/MS） analysis, a 21-kDa precursor of 19- kDa globulin was identified as the major storage protein for both cultivars. Some isoforms of peroxiredoxin and seed maturation protein were found to only exist in Shanyou63, whereas aldose reductase and starch granule-bound starch synthase were only detected in Liangyoupeijiu. These data might provide a foundation for further comparative studies of these two cultivars of hybrid rice.
文摘Implementation of efficient vibration control schemes for seismically excited structures is becoming more and more important in recent years.In this study,the influence of different control schemes on the dynamic performance of a frame structure excited by El Centro wave,with an emphasis on reaching law based control strategies,is examined.Reaching law refers to the reachable problem and criteria for the sliding state of a control system.Three reaching laws are designed to present different sliding mode control strategies by incorporating a state space model that describes structural dynamic characteristics of a frame structure.Both intact and damaged structures are studied by using the aforementioned control strategies.The influence of different structural damage extents,control locations and reaching law based control methods are further investigated.The results show that the structure can be well controlled using the sliding mode strategy when the induced structural damage extent does not exceed the standard percentage for considering the structure was damaged,which is 20%reduction in structure stiffness,as reported in the literature.The control effectiveness is more satisfactory if the control location is the same as the direction of external excitation.Furthermore,to study the chattering phenomenon of the sliding mode control method,approximation and detail components extracted from the phase plots of the sliding mode control system are compared via wavelet transform at different scales.The results show that for the same type of control law,the system behaves with similar chattering phenomenon.
基金Project supported by the Open Research Fund of State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering, Hohai University (Grant No. 2008491011)the Special Fund of State Key Laboratory of Hydrology-Water Resources and Hydraulic Engineering, Hohai University (Grant Nos. 2009585812, 2009586712)+1 种基金the Key Project of Chinese Ministry of Education (Grant No. 20100094120008)supported by the Funds for the Central Universities, Hohai University (Grant No. 2009B00214)
文摘Among existing remote sensing applications, land-based X-band radar is an effective technique to monitor the wave fields, and spatial wave information could be obtained from the radar images. Two-dimensional Fourier Transform （2-D FT） is the common algorithm to derive the spectra of radar images. However, the wave field in the nearshore area is highly non-homogeneous due to wave refraction, shoaling, and other coastal mechanisms. When applied in nearshore radar images, 2-D FT would lead to ambiguity of wave characteristics in wave number domain. In this article, we introduce two-dimensional Wavelet Transform （2-D WT） to capture the non-homogeneity of wave fields from nearshore radar images. The results show that wave number spectra by 2-D WT at six parallel space locations in the given image clearly present the shoaling of nearshore waves. Wave number of the peak wave energy is increasing along the inshore direction, and dominant direction of the spectra changes from South South West （SSW） to West South West （WSW）. To verify the results of 2-D WT, wave shoaling in radar images is calculated based on dispersion relation. The theoretical calculation results agree with the results of 2-D WT on the whole. The encouraging performance of 2-D WT indicates its strong capability of revealing the non-homogeneity of wave fields in nearshore X-band radar images.
