The Ru3(CO)12/PEDPA complex was firstly applied in the CO selective reduction of 4-propylthio-2-mitroaniline. The effects of reaction temperature, the pressure of CO and concentration of catalyst on the reduction were...The Ru3(CO)12/PEDPA complex was firstly applied in the CO selective reduction of 4-propylthio-2-mitroaniline. The effects of reaction temperature, the pressure of CO and concentration of catalyst on the reduction were investigated. Under the optimum conditions of T=140℃, Pco=5.0MPa and substrate/catalyst = 300 (molar ratio), the conversion and selectivity were 70% and 98%, respectively. After simple phase separation, the catalyst could be recycled.展开更多
A facile procedure for the synthesis of 3-（2′-amino-3′-cyano-4′-arylpyrid-6′-yl） coumarins are being reported starting from 3- acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out...A facile procedure for the synthesis of 3-（2′-amino-3′-cyano-4′-arylpyrid-6′-yl） coumarins are being reported starting from 3- acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR, ^1H NMR, and mass spectral data.展开更多
Condensation of substituted diethyl-malonates with phenylamidine hydrochloride give liquid crystals with a pyrimidine ring,which then subjeet graup transformation to give the title compound—5-cyano-2-(4-n-peatyl-4-bi...Condensation of substituted diethyl-malonates with phenylamidine hydrochloride give liquid crystals with a pyrimidine ring,which then subjeet graup transformation to give the title compound—5-cyano-2-(4-n-peatyl-4-biphenylyl) pyrimidine in high yield.展开更多
A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs...A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs F as a catalyst in the reaction of malononitrile and aryl aldehydes or isatins with 1,3-cyclohexanediones. The major advantages of this methodology are excellent yield at ambient temperature, very short reaction time（5–10 min）, and use of an inexpensive catalyst.展开更多
A novel and facile method toward a series of yellow water-borne polyurethane was developed by using an intrinsically colored diol in this paper.The yellow aqueous dispersion PCLD-HENA-PU was synthesized based on isoph...A novel and facile method toward a series of yellow water-borne polyurethane was developed by using an intrinsically colored diol in this paper.The yellow aqueous dispersion PCLD-HENA-PU was synthesized based on isophorone diisocyanate(IPDI), polycaprolactonediol(PCLD) and 2,2-dimethylol propionic acid(DMPA) using a yellow diol N,N-bis(2-hydroxyethyl)-4-nitroaniline (HENA) as a chain extender.Due to the complete reaction of OH group in colorant HENA with NCO group in diisocyanate,a series of stable yellow p...展开更多
An efficient method for the synthesis of novel benzo[b]pyrimido[4′,5′：5,4]thieno[2,3e]-[1,6]naphthyridine-8-one derivatives via Pictet-Spengler cyclization is reported. The reaction of 4-（3-aminopyrimido[4,5-d]thi...An efficient method for the synthesis of novel benzo[b]pyrimido[4′,5′：5,4]thieno[2,3e]-[1,6]naphthyridine-8-one derivatives via Pictet-Spengler cyclization is reported. The reaction of 4-（3-aminopyrimido[4,5-d]thieno-2-yl）quinoline-2-ones, which could be obtained from Thorpe-Ziegler isomerization of 4-bromomethylquinoline-2-ones and 5-cyano-1,6-dihydro-4-methyl-2-phenyl-6-thioxopyrimidine,with aromatic aldehydes in the presence of BF3·OEt2 gives pyrimidothieno[1,6]naphthyridines in good yields.展开更多
New mixed ligand chelates synthesized from di-and trivalent metal ions (Cr, Co, Ni, and Cu ions) and Schiff base (L1) resulted from the condensation of 4-dimethylaminobenzaldehyde with 2-aminophenol as primary ligand,...New mixed ligand chelates synthesized from di-and trivalent metal ions (Cr, Co, Ni, and Cu ions) and Schiff base (L1) resulted from the condensation of 4-dimethylaminobenzaldehyde with 2-aminophenol as primary ligand, whereas 2-nitroaniline (L2) represents the secondary ligand in a molar ratio of M:L1:L2 [1:1:1]. The synthesized Schiff base and chelates have been characterized by using several tools, such as, elemental analysis, molar conductivity, magnetic moment measurements, infrared and electronic spectra. The mass spectra of the ligands and Ni(II) chelate were used to justify the process of modification, as well as, the electron paramagnetic resonance spectrum which was carried out for Cu(II) chelate all in order to elucidate the chemical and geometrical structure of the chelates. On the basis of the obtained data, the geometry of the products was proposed for all the chelates.展开更多
An efficient three-component synthesis of 6-amino-4-aryl-5-cyano-3-metriyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles via a reaction between 3-methyl-1-phenyl-2-pyrazolin-5-one,aromatic aldehydes and malononitrile usi...An efficient three-component synthesis of 6-amino-4-aryl-5-cyano-3-metriyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles via a reaction between 3-methyl-1-phenyl-2-pyrazolin-5-one,aromatic aldehydes and malononitrile using tungstate sulfuric acid as a catalyst was described.Mild conditions,good to excellent yields,easily available catalyst and easy work-up are the key features of this method.展开更多
文摘The Ru3(CO)12/PEDPA complex was firstly applied in the CO selective reduction of 4-propylthio-2-mitroaniline. The effects of reaction temperature, the pressure of CO and concentration of catalyst on the reduction were investigated. Under the optimum conditions of T=140℃, Pco=5.0MPa and substrate/catalyst = 300 (molar ratio), the conversion and selectivity were 70% and 98%, respectively. After simple phase separation, the catalyst could be recycled.
基金the Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials for financial support(No.JSKC07041).
文摘A facile procedure for the synthesis of 3-（2′-amino-3′-cyano-4′-arylpyrid-6′-yl） coumarins are being reported starting from 3- acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR, ^1H NMR, and mass spectral data.
文摘Condensation of substituted diethyl-malonates with phenylamidine hydrochloride give liquid crystals with a pyrimidine ring,which then subjeet graup transformation to give the title compound—5-cyano-2-(4-n-peatyl-4-biphenylyl) pyrimidine in high yield.
基金SAIF Panjab University for providing analytical facilities for characterization of compounds
文摘A rapid, one-pot and highly efficient protocol for the synthesis of pharmaceutically interesting functionalized 2-amino-3-cyano-4H-pyran and spirooxindole derivatives has been developed using commercially available Cs F as a catalyst in the reaction of malononitrile and aryl aldehydes or isatins with 1,3-cyclohexanediones. The major advantages of this methodology are excellent yield at ambient temperature, very short reaction time（5–10 min）, and use of an inexpensive catalyst.
基金the National Natural Science Foundation of China(No.50273035)
文摘A novel and facile method toward a series of yellow water-borne polyurethane was developed by using an intrinsically colored diol in this paper.The yellow aqueous dispersion PCLD-HENA-PU was synthesized based on isophorone diisocyanate(IPDI), polycaprolactonediol(PCLD) and 2,2-dimethylol propionic acid(DMPA) using a yellow diol N,N-bis(2-hydroxyethyl)-4-nitroaniline (HENA) as a chain extender.Due to the complete reaction of OH group in colorant HENA with NCO group in diisocyanate,a series of stable yellow p...
文摘An efficient method for the synthesis of novel benzo[b]pyrimido[4′,5′：5,4]thieno[2,3e]-[1,6]naphthyridine-8-one derivatives via Pictet-Spengler cyclization is reported. The reaction of 4-（3-aminopyrimido[4,5-d]thieno-2-yl）quinoline-2-ones, which could be obtained from Thorpe-Ziegler isomerization of 4-bromomethylquinoline-2-ones and 5-cyano-1,6-dihydro-4-methyl-2-phenyl-6-thioxopyrimidine,with aromatic aldehydes in the presence of BF3·OEt2 gives pyrimidothieno[1,6]naphthyridines in good yields.
文摘New mixed ligand chelates synthesized from di-and trivalent metal ions (Cr, Co, Ni, and Cu ions) and Schiff base (L1) resulted from the condensation of 4-dimethylaminobenzaldehyde with 2-aminophenol as primary ligand, whereas 2-nitroaniline (L2) represents the secondary ligand in a molar ratio of M:L1:L2 [1:1:1]. The synthesized Schiff base and chelates have been characterized by using several tools, such as, elemental analysis, molar conductivity, magnetic moment measurements, infrared and electronic spectra. The mass spectra of the ligands and Ni(II) chelate were used to justify the process of modification, as well as, the electron paramagnetic resonance spectrum which was carried out for Cu(II) chelate all in order to elucidate the chemical and geometrical structure of the chelates. On the basis of the obtained data, the geometry of the products was proposed for all the chelates.
文摘An efficient three-component synthesis of 6-amino-4-aryl-5-cyano-3-metriyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles via a reaction between 3-methyl-1-phenyl-2-pyrazolin-5-one,aromatic aldehydes and malononitrile using tungstate sulfuric acid as a catalyst was described.Mild conditions,good to excellent yields,easily available catalyst and easy work-up are the key features of this method.
