This study examined the expression and distribution of angiopoietin-1/-2 （Ang-1/-2） in the endometrium of early pregnant mice. The expression of Ang-1/-2 was detected by immunohistochemical staining and in situ hybr...This study examined the expression and distribution of angiopoietin-1/-2 （Ang-1/-2） in the endometrium of early pregnant mice. The expression of Ang-1/-2 was detected by immunohistochemical staining and in situ hybridization respectively. Computerized image analysis system was used to measure the average optical intensity of Ang-1/-2 in endometria at different time points after gestation. Mice were randomly divided into 5 groups： control group, D2 group （2 days after pregnancy）, D4 group （4 days after pregnancy）, D6 group （6 days after pregnancy） and D8 group （8 days after pregnancy）, each containing 15 mice. The results showed that the expression of Ang-1 and Ang-2 was very different among 4 groups （P〈0.01）. Immunohistochemical staining revealed that Ang-1 was localized in the cytoplasma of stromal cells 2 days after pregnancy （day 2）, and in luminal epithelial cells on day 4. The protein of Ang-2 was mainly expressed in the cytoplasma of glandular epithelia and stromal cells. With gestation time, the positive reactions of Ang-1/-2 were stronger in the endometria of the pregnant mice （P〈0.01）. In situ hybridization showed Ang-I mRNA in stromal cells on day 2. Hybridization signal was localized in both stromal cells and vessel epithelial cells on day 4; Ang-2 mRNA was expressed in stromal cells and glandular epithelia on day 2; high mRNA levels appeared in stromal cells, glandular epithelia and vascular endothelia on day 4; an increasing in mRNA expression of Ang-1/-2 was observed on day 6 and day 8 （P〈0.01）. It is suggested that Ang-1/-2 may play an important role in the cross-talk between blastocyst and maternal endometrium during the process of embryo implantation.展开更多
We experimentally demonstrate a 4-Gb/s radio-over-fiber （RoF） system with 40-kin fiber and 2-m wireless distance downstream at 100-GHz carrier. To the best of our knowledge, this is for the first time in China to re...We experimentally demonstrate a 4-Gb/s radio-over-fiber （RoF） system with 40-kin fiber and 2-m wireless distance downstream at 100-GHz carrier. To the best of our knowledge, this is for the first time in China to realize optical wireless link at 100 GHz. In this letter, simple intensity modulator with direct detector （IM-DD） modulation is employed and optical power penalty afZer 40-kin single mode fiber （SMF）-28 and 2-m air link is 3.2 dB with bit-error-rate （BER） at 1 × 10- 9.展开更多
文摘This study examined the expression and distribution of angiopoietin-1/-2 （Ang-1/-2） in the endometrium of early pregnant mice. The expression of Ang-1/-2 was detected by immunohistochemical staining and in situ hybridization respectively. Computerized image analysis system was used to measure the average optical intensity of Ang-1/-2 in endometria at different time points after gestation. Mice were randomly divided into 5 groups： control group, D2 group （2 days after pregnancy）, D4 group （4 days after pregnancy）, D6 group （6 days after pregnancy） and D8 group （8 days after pregnancy）, each containing 15 mice. The results showed that the expression of Ang-1 and Ang-2 was very different among 4 groups （P〈0.01）. Immunohistochemical staining revealed that Ang-1 was localized in the cytoplasma of stromal cells 2 days after pregnancy （day 2）, and in luminal epithelial cells on day 4. The protein of Ang-2 was mainly expressed in the cytoplasma of glandular epithelia and stromal cells. With gestation time, the positive reactions of Ang-1/-2 were stronger in the endometria of the pregnant mice （P〈0.01）. In situ hybridization showed Ang-I mRNA in stromal cells on day 2. Hybridization signal was localized in both stromal cells and vessel epithelial cells on day 4; Ang-2 mRNA was expressed in stromal cells and glandular epithelia on day 2; high mRNA levels appeared in stromal cells, glandular epithelia and vascular endothelia on day 4; an increasing in mRNA expression of Ang-1/-2 was observed on day 6 and day 8 （P〈0.01）. It is suggested that Ang-1/-2 may play an important role in the cross-talk between blastocyst and maternal endometrium during the process of embryo implantation.
基金supported by the National "973" Program of China(No.2010CB328300)the National Natural Science Foundation of China(Nos.61107064,61177071,and 600837004)+1 种基金the Doctoral Fund of Ministry of Education,the Open Fund of State Key Lab of ASIC&System(No.11MS009)the Open Fund of State Key Lab of Information Photonics and Optical Communications
文摘We experimentally demonstrate a 4-Gb/s radio-over-fiber （RoF） system with 40-kin fiber and 2-m wireless distance downstream at 100-GHz carrier. To the best of our knowledge, this is for the first time in China to realize optical wireless link at 100 GHz. In this letter, simple intensity modulator with direct detector （IM-DD） modulation is employed and optical power penalty afZer 40-kin single mode fiber （SMF）-28 and 2-m air link is 3.2 dB with bit-error-rate （BER） at 1 × 10- 9.
