In this paper by Sobolev imbedding theorem and characterization theorem of generalized operators the existence of P(φ)2 quantum fields as generalized operators is obtained and a rigorous mathematical interpretation o...In this paper by Sobolev imbedding theorem and characterization theorem of generalized operators the existence of P(φ)2 quantum fields as generalized operators is obtained and a rigorous mathematical interpretation of renormalization procedure is given under white noise theory.展开更多
The dynamic traveling salesman problem(DTSP)is significant in logistics distribution in real-world applications in smart cities,but it is uncertain and difficult to solve.This paper proposes a scheme library-based ant...The dynamic traveling salesman problem(DTSP)is significant in logistics distribution in real-world applications in smart cities,but it is uncertain and difficult to solve.This paper proposes a scheme library-based ant colony optimization(ACO)with a two-optimization(2-opt)strategy to solve the DTSP efficiently.The work is novel and contributes to three aspects:problemmodel,optimization framework,and algorithmdesign.Firstly,in the problem model,traditional DTSP models often consider the change of travel distance between two nodes over time,while this paper focuses on a special DTSP model in that the node locations change dynamically over time.Secondly,in the optimization framework,the ACO algorithm is carried out in an offline optimization and online application framework to efficiently reuse the historical information to help fast respond to the dynamic environment.The framework of offline optimization and online application is proposed due to the fact that the environmental change inDTSPis caused by the change of node location,and therefore the newenvironment is somehowsimilar to certain previous environments.This way,in the offline optimization,the solutions for possible environmental changes are optimized in advance,and are stored in a mode scheme library.In the online application,when an environmental change is detected,the candidate solutions stored in the mode scheme library are reused via ACO to improve search efficiency and reduce computational complexity.Thirdly,in the algorithm design,the ACO cooperates with the 2-opt strategy to enhance search efficiency.To evaluate the performance of ACO with 2-opt,we design two challenging DTSP cases with up to 200 and 1379 nodes and compare them with other ACO and genetic algorithms.The experimental results show that ACO with 2-opt can solve the DTSPs effectively.展开更多
旨在研究犬腺病毒-2型(canine adenovirus type 2,CAV-2)作为溶瘤病毒的潜力并进一步探索精子黏附因子(SPAM1)协同CAV-2重塑肿瘤微环境在肿瘤免疫治疗中的应用价值。本研究以P15A-CAV-2反向遗传操作平台为基础,使用RED/ET同源重组系统...旨在研究犬腺病毒-2型(canine adenovirus type 2,CAV-2)作为溶瘤病毒的潜力并进一步探索精子黏附因子(SPAM1)协同CAV-2重塑肿瘤微环境在肿瘤免疫治疗中的应用价值。本研究以P15A-CAV-2反向遗传操作平台为基础,使用RED/ET同源重组系统构建携带SPAM1外源基因的中间载体,使用中间载体将CAV-2骨架载体E3区域缺失并替换SPAM1外源基因表达盒。再利用合成引物敲除kmccdB反向筛选表达盒构建P15A-CAV-2-mCMV-SPAM1-SV40 polyA感染性克隆质粒并在MDCK-E1A细胞系中拯救重组溶瘤病毒,对重组病毒体外溶瘤效应进行验证。根据测序与酶切验证结果证明,本研究成功构建并拯救出稳定表达外源基因SPAM1的重组溶瘤病毒1株;IFA试验证明,重组毒株能够高水平稳定表达外源基因且外源蛋白具有可弥散分布于细胞间的特点。缺失E3区域表达外源基因SPAM1的重组溶瘤病毒通过光镜观察和CCK8检测发现具有对犬癌细胞系A72强烈的杀伤效应。综上,本研究成功构建1株具有良好溶瘤效应的重组CAV-2,为后续应用于宠物肿瘤治疗奠定了基础。展开更多
The development of superconducting joining technology for reacted magnesium diboride(MgB_(2))conductors remains a critical challenge for the advancement of cryogen-free MgB_(2)-based magnets for magnetic resonance ima...The development of superconducting joining technology for reacted magnesium diboride(MgB_(2))conductors remains a critical challenge for the advancement of cryogen-free MgB_(2)-based magnets for magnetic resonance imaging(MRI).Herein,the fabrication of superconducting joints using reacted carbon-doped multifilament MgB_(2)wires for MRI magnets is reported.To achieve successful superconducting joints,the powder-in-mold method was employed,which involved tuning the filament protection mechanism,the powder compaction pressure,and the heat treatment condition.The fabricated joints demonstrated clear superconducting-to-normal transitions in self-field,with effective magnetic field screening up to 0.5 T at 20 K.To evaluate the interface between one of the MgB_(2)filaments and the MgB_(2)bulk within the joint,serial sectioning was conducted for the first time in this type of superconducting joint.The serial sectioning revealed space formation at the interface,potentially caused by the volume shrinkage associated with the MgB_(2)formation or the combined effect of the volume shrinkage and the different thermal expansion coefficients of the MgB_(2)bulk,the filament,the mold,and the sealing material.These findings are expected to be pivotal in developing MgB_(2)superconducting joining technology for MRI magnet applications through interface engineering.展开更多
Estimated ocean subsurface fields derived from satellite observations provide potential data sources for operational marine environmental monitoring and prediction systems.This study employs a statistic regression rec...Estimated ocean subsurface fields derived from satellite observations provide potential data sources for operational marine environmental monitoring and prediction systems.This study employs a statistic regression reconstruction method,in combination with domestic autonomous sea surface height and sea surface temperature observations from the Haiyang-2(HY-2)satellite fusion data,to establish an operational quasi-realtime three-dimensional(3D)temperature and salinity products over the Maritime Silk Road.These products feature a daily temporal resolution and a spatial resolution of 0.25°×0.25°and exhibit stability and continuity.We have demonstrated the accuracy of the reconstructed thermohaline fields in capturing the 3D thermohaline variations through comprehensive statistical evaluations,after comparing them against Argo observations and ocean analysis data from 2022.The results illustrate that the reconstructed fields effectively represent seasonal variations in oceanic subsurface structures,along with structural changes resulting from mesoscale processes,and the upper ocean’s responses to tropical cyclones.Furthermore,the incorporation of HY-2 satellite observations notably enhances the accuracy of temperature and salinity reconstructions in the Northwest Pacific Ocean and marginally improves salinity reconstruction accuracy in the North Indian Ocean when compared to the World Ocean Atlas 2018 monthly climatology thermohaline fields.As a result,the reconstructed product holds promise for providing quasi-real-time 3D temperature and salinity field information to facilitate fast decisionmaking during emergencies,and also offers foundational thermohaline fields for operational ocean reanalysis and forecasting systems.These contributions enhance the safety and stability of ocean subsurface activities and navigation.展开更多
We consider the quantum mechanical SU（2） transformation e^2λJzJ±e^-2λJz = e^±2λJ±as if the meaning of squeezing with e^±2λ being squeezing parameter. By studying SU（2） operators （J±,...We consider the quantum mechanical SU（2） transformation e^2λJzJ±e^-2λJz = e^±2λJ±as if the meaning of squeezing with e^±2λ being squeezing parameter. By studying SU（2） operators （J±, Jz） from the point of view of squeezing we find that （J±,Jz） can also be realized in terms of 3-mode bosonic operators. Employing this realization, we find the natural representation （the eigenvectors of J＋ or J-） of the 3-mode squeezing operator e^2λJz. The idea of considering quantum SU（2） transformation as if squeezing is liable for us to obtain the new bosonic operator realization of SU（2） and new squeezing operators.展开更多
By using the two-mode Fresnel operator we derive a multiplication rule of two-dimensional （2D） Collins diffraction formula, the inverse of 2D Collins diffraction integration can also be conveniently derived in this ...By using the two-mode Fresnel operator we derive a multiplication rule of two-dimensional （2D） Collins diffraction formula, the inverse of 2D Collins diffraction integration can also be conveniently derived in this way in the context of quantum optics theory.展开更多
In this paper,we are concerned with the existence of the positive bounded and blow-up radial solutions of the(k1,k2)-Hessian system■where G is a nonlinear operator,Ki=Ski(λ(D^(2) z_(i)))+ψ_(i)(|x|)|▽_(zi)|^(ki),i=...In this paper,we are concerned with the existence of the positive bounded and blow-up radial solutions of the(k1,k2)-Hessian system■where G is a nonlinear operator,Ki=Ski(λ(D^(2) z_(i)))+ψ_(i)(|x|)|▽_(zi)|^(ki),i=1,2.Under the appropriate conditions on gi and g2,our main results are obtained by using the monotone iterative method and the Arzela-Ascoli theorem.Furthermore,our main results also extend the previous existence results for both the single equation and systems.展开更多
1. Introduction In application of nonlinear boundary value problems, it is sometimes important to know that L~2-boundedness of a class of pseudo-differential operators with symbols whioh have nonsmooth coefficients. I...1. Introduction In application of nonlinear boundary value problems, it is sometimes important to know that L~2-boundedness of a class of pseudo-differential operators with symbols whioh have nonsmooth coefficients. In [2], Coifman and Meyer proved that the operator σ(x, D) is bounded in L~2(R~n) if its symbold (x, ξ) satisfies:展开更多
基金Project supported by NSFC (10171035) and Hubei University Youth Foundation (97A012)
文摘In this paper by Sobolev imbedding theorem and characterization theorem of generalized operators the existence of P(φ)2 quantum fields as generalized operators is obtained and a rigorous mathematical interpretation of renormalization procedure is given under white noise theory.
基金supported in part by the National Research Foundation of Korea (NRF-2021H1D3A2A01082705).
文摘The dynamic traveling salesman problem(DTSP)is significant in logistics distribution in real-world applications in smart cities,but it is uncertain and difficult to solve.This paper proposes a scheme library-based ant colony optimization(ACO)with a two-optimization(2-opt)strategy to solve the DTSP efficiently.The work is novel and contributes to three aspects:problemmodel,optimization framework,and algorithmdesign.Firstly,in the problem model,traditional DTSP models often consider the change of travel distance between two nodes over time,while this paper focuses on a special DTSP model in that the node locations change dynamically over time.Secondly,in the optimization framework,the ACO algorithm is carried out in an offline optimization and online application framework to efficiently reuse the historical information to help fast respond to the dynamic environment.The framework of offline optimization and online application is proposed due to the fact that the environmental change inDTSPis caused by the change of node location,and therefore the newenvironment is somehowsimilar to certain previous environments.This way,in the offline optimization,the solutions for possible environmental changes are optimized in advance,and are stored in a mode scheme library.In the online application,when an environmental change is detected,the candidate solutions stored in the mode scheme library are reused via ACO to improve search efficiency and reduce computational complexity.Thirdly,in the algorithm design,the ACO cooperates with the 2-opt strategy to enhance search efficiency.To evaluate the performance of ACO with 2-opt,we design two challenging DTSP cases with up to 200 and 1379 nodes and compare them with other ACO and genetic algorithms.The experimental results show that ACO with 2-opt can solve the DTSPs effectively.
文摘旨在研究犬腺病毒-2型(canine adenovirus type 2,CAV-2)作为溶瘤病毒的潜力并进一步探索精子黏附因子(SPAM1)协同CAV-2重塑肿瘤微环境在肿瘤免疫治疗中的应用价值。本研究以P15A-CAV-2反向遗传操作平台为基础,使用RED/ET同源重组系统构建携带SPAM1外源基因的中间载体,使用中间载体将CAV-2骨架载体E3区域缺失并替换SPAM1外源基因表达盒。再利用合成引物敲除kmccdB反向筛选表达盒构建P15A-CAV-2-mCMV-SPAM1-SV40 polyA感染性克隆质粒并在MDCK-E1A细胞系中拯救重组溶瘤病毒,对重组病毒体外溶瘤效应进行验证。根据测序与酶切验证结果证明,本研究成功构建并拯救出稳定表达外源基因SPAM1的重组溶瘤病毒1株;IFA试验证明,重组毒株能够高水平稳定表达外源基因且外源蛋白具有可弥散分布于细胞间的特点。缺失E3区域表达外源基因SPAM1的重组溶瘤病毒通过光镜观察和CCK8检测发现具有对犬癌细胞系A72强烈的杀伤效应。综上,本研究成功构建1株具有良好溶瘤效应的重组CAV-2,为后续应用于宠物肿瘤治疗奠定了基础。
基金the Japan Society for the Promotion of Science(JSPS)KAKENHI Grant Number JP18F18714Cryogenic Station,Research Network and Facility Services Division,National Institute for Materials Science(NIMS),Japansupported by the ARC Linkage Project(LP200200689)。
文摘The development of superconducting joining technology for reacted magnesium diboride(MgB_(2))conductors remains a critical challenge for the advancement of cryogen-free MgB_(2)-based magnets for magnetic resonance imaging(MRI).Herein,the fabrication of superconducting joints using reacted carbon-doped multifilament MgB_(2)wires for MRI magnets is reported.To achieve successful superconducting joints,the powder-in-mold method was employed,which involved tuning the filament protection mechanism,the powder compaction pressure,and the heat treatment condition.The fabricated joints demonstrated clear superconducting-to-normal transitions in self-field,with effective magnetic field screening up to 0.5 T at 20 K.To evaluate the interface between one of the MgB_(2)filaments and the MgB_(2)bulk within the joint,serial sectioning was conducted for the first time in this type of superconducting joint.The serial sectioning revealed space formation at the interface,potentially caused by the volume shrinkage associated with the MgB_(2)formation or the combined effect of the volume shrinkage and the different thermal expansion coefficients of the MgB_(2)bulk,the filament,the mold,and the sealing material.These findings are expected to be pivotal in developing MgB_(2)superconducting joining technology for MRI magnet applications through interface engineering.
基金The China-ASEAN Marine Cooperation Foundationthe Fundamental Research Funds for the Central Universities under contract No.B210203041+1 种基金the Postgraduate Research&Practice Innovation Program of Jiangsu Province under contract No.KYCX23_0657the opening project of the Key Laboratory of Marine Environmental Information Technology of Ministry of Natural Resources under contract No.521037412.
文摘Estimated ocean subsurface fields derived from satellite observations provide potential data sources for operational marine environmental monitoring and prediction systems.This study employs a statistic regression reconstruction method,in combination with domestic autonomous sea surface height and sea surface temperature observations from the Haiyang-2(HY-2)satellite fusion data,to establish an operational quasi-realtime three-dimensional(3D)temperature and salinity products over the Maritime Silk Road.These products feature a daily temporal resolution and a spatial resolution of 0.25°×0.25°and exhibit stability and continuity.We have demonstrated the accuracy of the reconstructed thermohaline fields in capturing the 3D thermohaline variations through comprehensive statistical evaluations,after comparing them against Argo observations and ocean analysis data from 2022.The results illustrate that the reconstructed fields effectively represent seasonal variations in oceanic subsurface structures,along with structural changes resulting from mesoscale processes,and the upper ocean’s responses to tropical cyclones.Furthermore,the incorporation of HY-2 satellite observations notably enhances the accuracy of temperature and salinity reconstructions in the Northwest Pacific Ocean and marginally improves salinity reconstruction accuracy in the North Indian Ocean when compared to the World Ocean Atlas 2018 monthly climatology thermohaline fields.As a result,the reconstructed product holds promise for providing quasi-real-time 3D temperature and salinity field information to facilitate fast decisionmaking during emergencies,and also offers foundational thermohaline fields for operational ocean reanalysis and forecasting systems.These contributions enhance the safety and stability of ocean subsurface activities and navigation.
基金supported by the National Natural Science Foundation of China(Grant Nos.11175113 and 11275123)the Key Project of Natural Science Fund of Anhui Province,China(Grant No.KJ2013A261)
文摘We consider the quantum mechanical SU（2） transformation e^2λJzJ±e^-2λJz = e^±2λJ±as if the meaning of squeezing with e^±2λ being squeezing parameter. By studying SU（2） operators （J±, Jz） from the point of view of squeezing we find that （J±,Jz） can also be realized in terms of 3-mode bosonic operators. Employing this realization, we find the natural representation （the eigenvectors of J＋ or J-） of the 3-mode squeezing operator e^2λJz. The idea of considering quantum SU（2） transformation as if squeezing is liable for us to obtain the new bosonic operator realization of SU（2） and new squeezing operators.
基金supported by the Doctoral Scientific Research Startup Fund of Anhui University, China (Grant No. 33190059)the National Natural Science Foundation of China (Grant No. 10874174)+1 种基金the Research Fund for the Doctoral Program of Higher Education of China (Grant No. 20113401120004)the Open Funds from National Laboratory for Infrared Physics, Chinese Academy of Sciences (Grant No. 201117)
文摘By using the two-mode Fresnel operator we derive a multiplication rule of two-dimensional （2D） Collins diffraction formula, the inverse of 2D Collins diffraction integration can also be conveniently derived in this way in the context of quantum optics theory.
基金supported by NSFC(12001344)the Graduate Education and Teaching Innovation Project of Shanxi,China(2021YJJG142)+1 种基金the Natural Science Foundation of Chongqing(cstc2020jcyj-msxmX0123)the Technology Research Foundation of Chongqing Educational Committee(KJQN201900539 and KJQN202000528)。
文摘In this paper,we are concerned with the existence of the positive bounded and blow-up radial solutions of the(k1,k2)-Hessian system■where G is a nonlinear operator,Ki=Ski(λ(D^(2) z_(i)))+ψ_(i)(|x|)|▽_(zi)|^(ki),i=1,2.Under the appropriate conditions on gi and g2,our main results are obtained by using the monotone iterative method and the Arzela-Ascoli theorem.Furthermore,our main results also extend the previous existence results for both the single equation and systems.
基金Project supported by the Science Fund of the Chinese Academy of Sciences.
文摘1. Introduction In application of nonlinear boundary value problems, it is sometimes important to know that L~2-boundedness of a class of pseudo-differential operators with symbols whioh have nonsmooth coefficients. In [2], Coifman and Meyer proved that the operator σ(x, D) is bounded in L~2(R~n) if its symbold (x, ξ) satisfies:
