BACKGROUND Extragonadal yolk sac tumors(YSTs)are rare,with only a low reported tumor occurrence outside the gonads locally and abroad.Extragonadal YSTs are usually a diagnostic challenge,because they are infrequent,bu...BACKGROUND Extragonadal yolk sac tumors(YSTs)are rare,with only a low reported tumor occurrence outside the gonads locally and abroad.Extragonadal YSTs are usually a diagnostic challenge,because they are infrequent,but also because a thoughtful and detailed differential diagnostic process must be performed.CASE SUMMARY Here we present a case of an abdominal wall YST in a 20-year-old woman admitted with a tumor in the lower abdomen close to the umbilicus.The tumorectomy was performed.The histological examination revealed characteristic findings such as Schiller-Duval bodies,loose reticular structures,papillary structures,and eosinophilic globules.According to the immunohistochemical staining,the tumor tissue was positive for broad-spectrum cytokeratin,Spalt-like transcription factor 4,glypican-3,CD117,and epithelial membrane antigen.Based on the clinical information,histological features,and immunohistochemical staining profile,the tumor was diagnosed as a YST present in the abdominal wall.CONCLUSION Based on the clinical information,histological features,and immunohistochemical staining profile described above,the tumor was diagnosed as a primary YST in the abdominal wall.展开更多
基金Supported by National Natural Science Foundation of China(Grant No.82103624 to Wang Y)Horizontal Project of Jinzhou Medical University(Grant No.STC-2S21094 to Yang J).
文摘BACKGROUND Extragonadal yolk sac tumors(YSTs)are rare,with only a low reported tumor occurrence outside the gonads locally and abroad.Extragonadal YSTs are usually a diagnostic challenge,because they are infrequent,but also because a thoughtful and detailed differential diagnostic process must be performed.CASE SUMMARY Here we present a case of an abdominal wall YST in a 20-year-old woman admitted with a tumor in the lower abdomen close to the umbilicus.The tumorectomy was performed.The histological examination revealed characteristic findings such as Schiller-Duval bodies,loose reticular structures,papillary structures,and eosinophilic globules.According to the immunohistochemical staining,the tumor tissue was positive for broad-spectrum cytokeratin,Spalt-like transcription factor 4,glypican-3,CD117,and epithelial membrane antigen.Based on the clinical information,histological features,and immunohistochemical staining profile,the tumor was diagnosed as a YST present in the abdominal wall.CONCLUSION Based on the clinical information,histological features,and immunohistochemical staining profile described above,the tumor was diagnosed as a primary YST in the abdominal wall.